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Journal of Liposome Research Volume 3, 1993 - Issue 3
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Research Article

Preclinical Studies with Doxorubicin Encapsulated in Polyethyleneglycol-Coated Liposomes

Alberto A. Gabizon Departments of Oncology and Pathology, Hadassah University Hospital, Jerusalem, 91120, Israel
,
Orit Pappo Departments of Oncology and Pathology, Hadassah University Hospital, Jerusalem, 91120, Israel
,
Dorit Goren Departments of Oncology and Pathology, Hadassah University Hospital, Jerusalem, 91120, Israel
,
Michal Chemla Departments of Oncology and Pathology, Hadassah University Hospital, Jerusalem, 91120, Israel
,
Dinah Tzemach Departments of Oncology and Pathology, Hadassah University Hospital, Jerusalem, 91120, Israel
&
Aviva T. Horowitz Departments of Oncology and Pathology, Hadassah University Hospital, Jerusalem, 91120, Israel
Pages 517-528 | Published online: 28 Sep 2008

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Alberto A. Gabizon. (2001) Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy. Cancer Investigation 19:4, pages 424-436.
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Articles from other publishers (24)

Mahsa Bagheri, Marcel H. Fens, Tony G. Kleijn, Robin B. Capomaccio, Dora Mehn, Przemek M. Krawczyk, Enzo M. Scutigliani, Andrei Gurinov, Marc Baldus, Nicky C. H. van Kronenburg, Robbert J. Kok, Michal Heger, Cornelus F. van Nostrum & Wim E. Hennink. (2021) In Vitro and In Vivo Studies on HPMA-Based Polymeric Micelles Loaded with Curcumin . Molecular Pharmaceutics 18:3, pages 1247-1263.
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Sara Zalba, Ann L. B. Seynhaeve, Jos F. Brouwers, Regine Süss, Marcel Verheij & Timo L. M. ten Hagen. (2020) Sensitization of drug resistant sarcoma tumors by membrane modulation via short chain sphingolipid-containing nanoparticles . Nanoscale 12:32, pages 16967-16979.
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Chuanqi Peng, Jing Xu, Mengxiao Yu, Xuhui Ning, Yingyu Huang, Bujie Du, Elizabeth Hernandez, Payal Kapur, Jer‐Tsong Hsieh & Jie Zheng. (2019) Tuning the In Vivo Transport of Anticancer Drugs Using Renal‐Clearable Gold Nanoparticles. Angewandte Chemie International Edition 58:25, pages 8479-8483.
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Chuanqi Peng, Jing Xu, Mengxiao Yu, Xuhui Ning, Yingyu Huang, Bujie Du, Elizabeth Hernandez, Payal Kapur, Jer‐Tsong Hsieh & Jie Zheng. (2019) Tuning the In Vivo Transport of Anticancer Drugs Using Renal‐Clearable Gold Nanoparticles. Angewandte Chemie.
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Yun Chen, Jingsheng Huang, Shiyong Zhang & Zhongwei Gu. (2017) Superamphiphile Based Cross-Linked Small-Molecule Micelles for pH-Triggered Release of Anticancer Drugs. Chemistry of Materials 29:7, pages 3083-3091.
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Gina Song, Oscar T. Suzuki, Charlene M. Santos, Andrew T. Lucas, Tim Wiltshire & William C. Zamboni. (2016) Gulp1 is associated with the pharmacokinetics of PEGylated liposomal doxorubicin (PLD) in inbred mouse strains. Nanomedicine: Nanotechnology, Biology and Medicine 12:7, pages 2007-2017.
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Torben Gjetting, Thomas Lars Andresen, Camilla Laulund Christensen, Frederik Cramer, Thomas Tuxen Poulsen & Hans Skovgaard Poulsen. (2011) A simple protocol for preparation of a liposomal vesicle with encapsulated plasmid DNA that mediate high accumulation and reporter gene activity in tumor tissue. Results in Pharma Sciences 1:1, pages 49-56.
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Rebecca Solomon & Alberto A. Gabizon. (2008) Clinical Pharmacology of Liposomal Anthracyclines: Focus on Pegylated Liposomal Doxorubicin. Clinical Lymphoma and Myeloma 8:1, pages 21-32.
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Masahiro YamauchiKyoko TsutsumiMasayuki AbeYoichi UosakiMasashi NakakuraNoboru Aoki. (2007) Release of Drugs from Liposomes Varies with Particle Size. Biological and Pharmaceutical Bulletin 30:5, pages 963-966.
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Alberto A. Gabizon, Dinah Tzemach, Aviva T. Horowitz, Hilary Shmeeda, Jerry Yeh & Samuel Zalipsky. (2006) Reduced Toxicity and Superior Therapeutic Activity of a Mitomycin C Lipid-Based Prodrug Incorporated in Pegylated Liposomes. Clinical Cancer Research 12:6, pages 1913-1920.
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Howard D. Homesley, John A. Blessing, Joel Sorosky, Gary Reid & Katherine Y. Look. (2005) Phase II trial of liposomal doxorubicin at 40 mg/m2 every 4 weeks in endometrial carcinoma: A Gynecologic Oncology Group Study. Gynecologic Oncology 98:2, pages 294-298.
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Noa STETTNER, Ori BRENNER, Raya EILAM & Alon HARMELIN. (2005) Pegylated Liposomal Doxorubicin as a Chemotherapeutic Agent for Treatment of Canine Transmissible Venereal Tumor in Murine Models. Journal of Veterinary Medical Science 67:11, pages 1133-1139.
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David S. Alberts, Franco M. Muggia, James Carmichael, Eric P. Winer, Mohammad Jahanzeb, Alan P. Venook, Keith M. Skubitz, Edgardo Rivera, Joseph A. Sparano, Nicholas J. Dibella, Simon J. Stewart, John J. Kavanagh & Alberto A. Gabizon. (2004) Efficacy and safety of liposomal anthracyclines in Phase I/II clinical trials. Seminars in Oncology 31, pages 53-90.
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Alberto Gabizon, Hilary Shmeeda & Yechezkel Barenholz. (2003) Pharmacokinetics of Pegylated Liposomal Doxorubicin. Clinical Pharmacokinetics 42:5, pages 419-436.
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Christien Oussoren, Gert Storm, Daan Crommelin & Judy Senior. 2000. Sustained-Release Injectable Products. Sustained-Release Injectable Products 137 180 .
Farida Kadir, Christien Oussoren & Daan Crommelin. 1999. Injectable Drug Development. Injectable Drug Development 337 354 .
C. Oussoren, W.M.C. Eling, D.J.A. Crommelin, G. Storm & J. Zuidema. (1998) The influence of the route of administration and liposome composition on the potential of liposomes to protect tissue against local toxicity of two antitumor drugs. Biochimica et Biophysica Acta (BBA) - Biomembranes 1369:1, pages 159-172.
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DORIT GOREN & ALBERTO GABIZON. 1998. Medical Applications of Liposomes. Medical Applications of Liposomes 259 274 .
Alberto A. Gabizon & Franco M. Muggia. 1998. Long Circulating Liposomes: Old Drugs, New Therapeutics. Long Circulating Liposomes: Old Drugs, New Therapeutics 165 174 .
Dorit Goren, Samuel Zalipsky, Aviva T. Horowitz & Alberto Gabizon. 1998. Targeting of Drugs 6. Targeting of Drugs 6 77 85 .
Alberto Gabizon, Dorit Goren, Aviva T. Horowitz, Dinah Tzemach, Alexander Lossos & Tali Siegal. (1997) Long-circulating liposomes for drug delivery in cancer therapy: a review of biodistribution studies in tumor-bearing animals. Advanced Drug Delivery Reviews 24:2-3, pages 337-344.
Crossref
Tali Siegal, Aviva Horowitz & Alberto Gabizon. (1995) Doxorubicin encapsulated in sterically stabilized liposomes for the treatment of a brain tumor model: biodistribution and therapeutic efficacy. Journal of Neurosurgery 83:6, pages 1029-1037.
Crossref
Alberto A. Gabizon. (1995) Liposome circulation time and tumor targeting: implications for cancer chemotherapy. Advanced Drug Delivery Reviews 16:2-3, pages 285-294.
Crossref
Martin C. Woodle. (1995) Sterically stabilized liposome therapeutics. Advanced Drug Delivery Reviews 16:2-3, pages 249-265.
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