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Original Article

Design and Baseline Data of a Randomized Trial to Evaluate Coverage and Frequency of Mass Treatment with Azithromycin: The Partnership for Rapid Elimination of Trachoma (PRET) in Tanzania and The Gambia

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Pages 20-29 | Received 07 Apr 2010, Accepted 24 Nov 2010, Published online: 28 Jan 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Abdou Amza, Boubacar Kadri, Beido Nassirou, Sun Y Cotter, Nicole E. Stoller, Sheila K West, Robin L. Bailey, Travis C. Porco, Jeremy D. Keenan, Thomas M. Lietman & Catherine E. Oldenburg. (2019) Community-level Association between Clinical Trachoma and Ocular Chlamydia Infection after MASS Azithromycin Distribution in a Mesoendemic Region of Niger. Ophthalmic Epidemiology 26:4, pages 231-237.
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Ann-Margret Ervin, Harran Mkocha, Beatriz Munoz, Kurt Dreger, Laura Dize, Charlotte Gaydos, Thomas C. Quinn & Sheila K. West. (2016) Surveillance and Azithromycin Treatment for Newcomers and Travelers Evaluation (ASANTE) Trial: Design and Baseline Characteristics. Ophthalmic Epidemiology 23:6, pages 347-353.
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Sheila K. West, Beatriz E. Munoz, Harran Mkocha, Charlotte Gaydos & Thomas Quinn. (2015) Risk of Infection with Chlamydia trachomatis from Migrants to Communities Undergoing Mass Drug Administration for Trachoma Control. Ophthalmic Epidemiology 22:3, pages 170-175.
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Sheila K West & Harran Mkocha. (2013) Azithromycin use for trachoma control: lessons learned from Tanzania. Expert Review of Ophthalmology 8:3, pages 245-253.
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Articles from other publishers (57)

Daniel Milad, Fares Antaki, Marie-Claude Robert & Renaud Duval. (2023) Development and deployment of a smartphone application for diagnosing trachoma: Leveraging code-free deep learning and edge artificial intelligence. Saudi Journal of Ophthalmology 37:3, pages 200.
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Ehsan Ghasemian, Aleksandra Inic-Kanada, Astrid Collingro, Lamiss Mejdoubi, Hadeel Alchalabi, Darja Keše, Balgesa Elkheir Elshafie, Jaouad Hammou & Talin Barisani-Asenbauer. (2021) Comparison of genovars and Chlamydia trachomatis infection loads in ocular samples from children in two distinct cohorts in Sudan and Morocco. PLOS Neglected Tropical Diseases 15:8, pages e0009655.
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Rebecca A. Gladstone, Ebrima Bojang, John Hart, Emma M. Harding-Esch, David Mabey, Ansumana Sillah, Robin L. Bailey, Sarah E. Burr, Anna Roca, Stephen D. Bentley & Martin J. Holland. (2021) Mass drug administration with azithromycin for trachoma elimination and the population structure of Streptococcus pneumoniae in the nasopharynx. Clinical Microbiology and Infection 27:6, pages 864-870.
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John M. NesemannMichael I. SeiderBlake M. SnyderRobi N. MaamariDaniel A. FletcherBerhan A. HaileZerihun TadesseNicole E. VarnadoSun Y. CotterElizabeth Kelly CallahanPaul M. EmersonTodd P. MargolisThomas M. LietmanJeremy D. Keenan. (2020) Comparison of Smartphone Photography, Single-Lens Reflex Photography, and Field-Grading for Trachoma. The American Journal of Tropical Medicine and Hygiene 103:6, pages 2488-2491.
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Kieran S O’Brien, Abdou Amza, Boubacar Kadri, Beido Nassirou, Sun Y Cotter, Nicole E Stoller, Sheila K West, Robin L Bailey, Travis C Porco, Jeremy D Keenan, Thomas M Lietman & Catherine E Oldenburg. (2019) Comparison of anthropometric indicators to predict mortality in a population-based prospective study of children under 5 years in Niger. Public Health Nutrition, pages 1-6.
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Kieran S. O’Brien, Sun Y. Cotter, Abdou Amza, Boubacar Kadri, Beido Nassirou, Nicole E. Stoller, Zhaoxia Zhou, Sheila K. West, Robin L. Bailey, Jeremy D. Keenan, Travis C. Porco & Thomas M. Lietman. (2018) Childhood Mortality After Mass Distribution of Azithromycin. Pediatric Infectious Disease Journal 37:11, pages 1082-1086.
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Robin L. BaileySheila K. WestNicole E. StollerCatherine E. Oldenburg, Sun Y. CotterThomas M. LietmanBaido NassirouBruce D. GaynorBoubacar KadriTravis C. PorcoAbdou AmzaKieran S. O’Brien. (2018) Anthropometry and Malaria among Children in Niger: A Cross-Sectional Study. The American Journal of Tropical Medicine and Hygiene 99:3, pages 665-669.
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Catherine E. Oldenburg, Abdou Amza, Boubacar Kadri, Beido Nassirou, Sun Y. Cotter, Nicole E. Stoller, Sheila K. West, Robin L. Bailey, Travis C. Porco, Jeremy D. Keenan, Thomas M. Lietman & Bruce D. Gaynor. (2018) Annual Versus Biannual Mass Azithromycin Distribution and Malaria Parasitemia During the Peak Transmission Season Among Children in Niger. Pediatric Infectious Disease Journal 37:6, pages 506-510.
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Abdou Amza, Boubacar Kadri, Beido Nassirou, Sun Y Cotter, Nicole E Stoller, Sheila K West, Robin L Bailey, Travis C Porco, Bruce D Gaynor, Jeremy D Keenan, Thomas M Lietman & Catherine E Oldenburg. (2018) Effectiveness of expanding annual mass azithromycin distribution treatment coverage for trachoma in Niger: a cluster randomised trial. British Journal of Ophthalmology 102:5, pages 680-686.
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Jeremy D Keenan, Stephanie A Chin, Abdou Amza, Boubacar Kadri, Baido Nassirou, Vicky Cevallos, Sun Y Cotter, Zhaoxia Zhou, Sheila K West, Robin L Bailey, Travis C Porco & Thomas M Lietman. (2018) The Effect of Antibiotic Selection Pressure on the Nasopharyngeal Macrolide Resistome: A Cluster-randomized Trial. Clinical Infectious Diseases.
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Rabia Karani, Meraf Wolle, Harran Mkocha, Beatriz Muñoz & Sheila K West. (2018) Risk factors for incidence of trachomatous scarring in a cohort of women in low endemic district. British Journal of Ophthalmology 102:4, pages 419-423.
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Catherine E. OldenburgAbdou AmzaBoubacar KadriBeido NassirouSun Y. CotterNicole E. StollerSheila K. WestRobin L. BaileyTravis C. Porco, Bruce D. GaynorJeremy D. Keenan & Thomas M. Lietman. (2018) Comparison of Mass Azithromycin Coverage Targets of Children in Niger: A Cluster-Randomized Trachoma Trial. The American Journal of Tropical Medicine and Hygiene 98:2, pages 389-395.
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Jacob T. Cox, Harran Mkocha, Beatriz Munoz & Sheila K. West. (2017) Trachomatous scarring among children in a formerly hyper-endemic district of Tanzania. PLOS Neglected Tropical Diseases 11:12, pages e0006085.
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Ebrima Bojang, James Jafali, Vincent Perreten, John Hart, Emma M. Harding-Esch, Ansumana Sillah, David C. W. Mabey, Martin J. Holland, Robin L. Bailey, Anna Roca & Sarah E. Burr. (2017) Short-term increase in prevalence of nasopharyngeal carriage of macrolide-resistant Staphylococcus aureus following mass drug administration with azithromycin for trachoma control. BMC Microbiology 17:1.
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Kieran S. O'BrienSun Y. CotterAbdou AmzaBoubacar KadriBaido NassirouNicole E. StollerZhaoxia ZhouChris CotterSheila K. WestRobin L. BaileyPhilip J. RosenthalBruce D. GaynorTravis C. PorcoThomas M. Lietman. (2017) Mass Azithromycin and Malaria Parasitemia in Niger: Results from a Community-Randomized Trial. The American Journal of Tropical Medicine and Hygiene 97:3, pages 696-701.
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Anna Last, Sarah Burr, Neal Alexander, Emma Harding-Esch, Chrissy H. Roberts, Meno Nabicassa, Eunice Teixeira da Silva Cassama, David Mabey, Martin Holland & Robin Bailey. (2017) Spatial clustering of high load ocular Chlamydia trachomatis infection in trachoma: a cross-sectional population-based study. Pathogens and Disease 75:5.
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Sheila K. West, Beatriz Munoz, Harran Mkocha, Laura Dize, Charlotte A. Gaydos, Bonnie Swenor, Ann-Margret Ervin & Thomas C. Quinn. (2017) Treating village newcomers and travelers for trachoma: Results from ASANTE cluster randomized trial. PLOS ONE 12:6, pages e0178595.
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Athumani M. Ramadhani, Tamsyn Derrick, David Macleod, Martin J. Holland & Matthew J. Burton. (2016) The Relationship between Active Trachoma and Ocular Chlamydia trachomatis Infection before and after Mass Antibiotic Treatment. PLOS Neglected Tropical Diseases 10:10, pages e0005080.
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Bidya P Prasad, Ramesh C Bhatta, JSP Chaudhary, Shekhar Sharma, Sailesh Mishra, Puja A Cuddapah, Nicole E Stoller, Sun N Yu, Salman A Rahman, Michael Deiner, Jeremy D Keenan & Bruce D Gaynor. (2016) Agreement between novice and experienced trachoma graders improves after a single day of didactic training. British Journal of Ophthalmology 100:6, pages 762-765.
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Manoj Gambhir & Amy Pinsent. (2015) Possible changes in the transmissibility of trachoma following MDA and transmission reduction: implications for the GET2020 goals. Parasites & Vectors 8:1.
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Elizabeth N. Ssemanda, Harran Mkocha, Joshua Levens, Beatriz Munoz & Sheila K. West. (2015) Community mass treatment with azithromycin for trachoma: Factors associated with change in participation of children from the first to the second round. Clinical Epidemiology and Global Health 3:1, pages 37-43.
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Violeta Jimenez, Huub C. Gelderblom, Rebecca Mann Flueckiger, Paul M. Emerson & Danny Haddad. (2015) Mass Drug Administration for Trachoma: How Long Is Not Long Enough?. PLOS Neglected Tropical Diseases 9:3, pages e0003610.
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L. Dize, C. A. Gaydos, T. C. Quinn & S. K. West. (2015) Stability of Chlamydia trachomatis on Storage of Dry Swabs for Accurate Detection by Nucleic Acid Amplification Tests. Journal of Clinical Microbiology 53:3, pages 1046-1047.
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Sarah E Burr, John Hart, Tansy Edwards, Emma M Harding-Esch, Martin J Holland, David C W Mabey, Ansumana Sillah & Robin L Bailey. (2014) Anthropometric indices of Gambian children after one or three annual rounds of mass drug administration with azithromycin for trachoma control. BMC Public Health 14:1.
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Alexander Jenson, Catherine Gracewello, Harran Mkocha, Debra Roter, Beatriz Munoz & Sheila West. (2014) Gender and performance of community treatment assistants in Tanzania. International Journal for Quality in Health Care 26:5, pages 524-529.
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Jessica C Seidman, Christian L Coles, Ellen K Silbergeld, Joshua Levens, Harran Mkocha, Lashaunda B Johnson, Beatriz Muñoz & Sheila K West. (2014) Increased carriage of macrolide-resistant fecal E. coli following mass distribution of azithromycin for trachoma control . International Journal of Epidemiology 43:4, pages 1105-1113.
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Sarah E BurrSally MilneJames JafaliEbrima BojangMegha RajasekharJohn HartEmma M Harding-EschMartin J HollandDavid CW MabeyAnsumana SillahRobin L BaileyAnna Roca. (2014) Mass administration of azithromycin and Streptococcus pneumoniae carriage: cross-sectional surveys in the Gambia . Bulletin of the World Health Organization 92:7, pages 490-498.
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S. K. West, J. Moncada, B. Munoz, H. Mkocha, P. Storey, J. Hardick, C. A. Gaydos, T. C. Quinn & J. Schachter. (2014) Is There Evidence for Resistance of Ocular Chlamydia trachomatis to Azithromycin After Mass Treatment for Trachoma Control?. Journal of Infectious Diseases 210:1, pages 65-71.
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Anna R. Last, Sarah E. Burr, Helen A. Weiss, Emma M. Harding-Esch, Eunice Cassama, Meno Nabicassa, David C. Mabey, Martin J. Holland & Robin L. Bailey. (2014) Risk Factors for Active Trachoma and Ocular Chlamydia trachomatis Infection in Treatment-Naïve Trachoma-Hyperendemic Communities of the Bijagós Archipelago, Guinea Bissau. PLoS Neglected Tropical Diseases 8:6, pages e2900.
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Laura Dize, Sheila West, Thomas C. Quinn & Charlotte A. Gaydos. (2013) Pooling ocular swab specimens from Tanzania for testing by Roche Amplicor and Aptima Combo 2 assays for the detection of Chlamydia trachomatis: accuracy and cost-savings. Diagnostic Microbiology and Infectious Disease 77:4, pages 289-291.
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Fengchen Liu, Travis C. Porco, Kathryn J. Ray, Robin L. Bailey, Harran Mkocha, Beatriz Mu?oz, Thomas C. Quinn, Thomas M. Lietman & Sheila K. West. (2013) Assessment of Transmission in Trachoma Programs over Time Suggests No Short-Term Loss of Immunity. PLoS Neglected Tropical Diseases 7:7, pages e2303.
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Chrissy h. Roberts, Anna Last, Sandra Molina-Gonzalez, Eunice Cassama, Robert Butcher, Meno Nabicassa, Elizabeth McCarthy, Sarah E. Burr, David C. Mabey, Robin L. Bailey & Martin J. Holland. (2013) Development and Evaluation of a Next-Generation Digital PCR Diagnostic Assay for Ocular Chlamydia trachomatis Infections. Journal of Clinical Microbiology 51:7, pages 2195-2203.
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Emma M. Harding-Esch, Ansumana Sillah, Tansy Edwards, Sarah E. Burr, John D. Hart, Hassan Joof, Mass Laye, Pateh Makalo, Ahmed Manjang, Sandra Molina, Isatou Sarr-Sissoho, Thomas C. Quinn, Tom Lietman, Martin J. Holland, David Mabey, Sheila K. West & Robin Bailey. (2013) Mass Treatment with Azithromycin for Trachoma: When Is One Round Enough? Results from the PRET Trial in The Gambia. PLoS Neglected Tropical Diseases 7:6, pages e2115.
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Laura Dize, Sheila West, James A. Williams, Barbara Van Der Pol, Thomas C. Quinn & Charlotte A. Gaydos. (2013) Comparison of the Abbott m 2000 RealTi m e CT Assay and the Cepheid GeneXpert CT/NG Assay to the Roche Amplicor CT Assay for Detection of Chlamydia trachomatis in Ocular Samples from Tanzania . Journal of Clinical Microbiology 51:5, pages 1611-1613.
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Abdou Amza, Boubacar Kadri, Baido Nassirou, Sun N. Yu, Nicole E. Stoller, Satasuk J. Bhosai, Zhaoxia Zhou, Charles E. McCulloch, Sheila K. West, Robin L. Bailey, Jeremy D. Keenan, Thomas M. Lietman & Bruce D. Gaynor. (2013) The Easiest Children to Reach Are Most Likely to Be Infected with Ocular Chlamydia trachomatis in Trachoma Endemic Areas of Niger. PLoS Neglected Tropical Diseases 7:1, pages e1983.
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Abdou Amza, Boubacar Kadri, Baido Nassirou, Nicole E. Stoller, Sun N. Yu, Zhaoxia Zhou, Sheila K. West, David C. W. Mabey, Robin L. Bailey, Jeremy D. Keenan, Travis C. Porco, Thomas M. Lietman & Bruce D. Gaynor. (2013) A Cluster-Randomized Controlled Trial Evaluating the Effects of Mass Azithromycin Treatment on Growth and Nutrition in Niger. The American Journal of Tropical Medicine and Hygiene 88:1, pages 138-143.
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E. Brook Goodhew, Jeffrey W. Priest, Delynn M. Moss, Guangming Zhong, Beatriz Munoz, Harran Mkocha, Diana L. Martin, Sheila K. West, Charlotte Gaydos & Patrick J. Lammie. (2012) CT694 and pgp3 as Serological Tools for Monitoring Trachoma Programs. PLoS Neglected Tropical Diseases 6:11, pages e1873.
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. (2012) Current World Literature. Current Opinion in Ophthalmology 23:4, pages 330-335.
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Abdou Amza, Boubacar Kadri, Baido Nassirou, Nicole E. Stoller, Sun N. Yu, Zhaoxia Zhou, Stephanie Chin, Sheila K. West, Robin L. Bailey, David C. W. Mabey, Jeremy D. Keenan, Travis C. Porco, Thomas M. Lietman & Bruce D. Gaynor. (2012) Community Risk Factors for Ocular Chlamydia Infection in Niger: Pre-Treatment Results from a Cluster-Randomized Trachoma Trial. PLoS Neglected Tropical Diseases 6:4, pages e1586.
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Elizabeth N. Ssemanda, Joshua Levens, Harran Mkocha, Beatriz Munoz & Sheila K. West. (2012) Azithromycin Mass Treatment for Trachoma Control: Risk Factors for Non-Participation of Children in Two Treatment Rounds. PLoS Neglected Tropical Diseases 6:3, pages e1576.
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