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Review: GnRH Antagonist and IVF in PCO Patients

Effectiveness of GnRH antagonist in the treatment of patients with polycystic ovary syndrome undergoing IVF: a systematic review and meta analysis

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Pages 187-191 | Received 14 Aug 2012, Accepted 14 Sep 2012, Published online: 30 Nov 2012

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Jie Li, Yan Sun, Sien Mo, Shujia Wang & Weiwei Luo. (2021) Effects of oral contraceptive for different responder women before GnRH antagonists: a systematic review and meta-analysis. Gynecological Endocrinology 37:11, pages 977-986.
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Wan Yang, Rui Yang, Shuo Yang, Jia Li, Binbin Tu, Chang Gao & Ying Wang. (2018) Infertile polycystic ovary syndrome patients undergoing in vitro fertilization with the gonadotropin-releasing hormone-antagonist protocol: role of hyperandrogenism. Gynecological Endocrinology 34:8, pages 715-718.
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Boriana Benbassat, Konstantin Mitov, Alexandra Savova, Konstantin Tachkov & Guenka Petrova. (2017) Cost-effectiveness of different types of COH protocols for in vitro fertilization at national level. Biotechnology & Biotechnological Equipment 31:1, pages 206-214.
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Morena Luigia Rocca, Roberta Venturella, Rita Mocciaro, Annalisa Di Cello, Angela Sacchinelli, Valentina Russo, Simona Trapasso, Fulvio Zullo & Michele Morelli. (2015) Polycystic ovary syndrome: chemical pharmacotherapy. Expert Opinion on Pharmacotherapy 16:9, pages 1369-1393.
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Jun-xia Liang, Yu Zhang, Chun-hui Xiao, Shan Cao, Ying Tian, Na-na Wang & Chong Liu. (2023) Application value of tumor necrosis factor inhibitors in in vitro fertilization-embryo transfer in infertile women with polycystic ovary syndrome. BMC Pregnancy and Childbirth 23:1.
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Rui Gao, Xin Liao, Wanrong Huang, Rujun Zeng, Lang Qin & Peng Bai. (2022) Follicular-Phase GnRH Agonist Protocol Is Another Choice for Polycystic Ovary Syndrome Patients With Lower LH/FSH and Lower AMH Levels Without Increasing Severe OHSS Risk. Frontiers in Endocrinology 13.
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Sally Kadoura, Marwan Alhalabi & Abdul Hakim Nattouf. (2022) Conventional GnRH antagonist protocols versus long GnRH agonist protocol in IVF/ICSI cycles of polycystic ovary syndrome women: a systematic review and meta-analysis. Scientific Reports 12:1.
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Jingwei Yang, Xiaodong Zhang, Xiaoyan Ding, Yuting Wang, Guoning Huang & Hong Ye. (2021) Cumulative live birth rates between GnRH-agonist long and GnRH-antagonist protocol in one ART cycle when all embryos transferred: real-word data of 18,853 women from China. Reproductive Biology and Endocrinology 19:1.
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Mei Dong, Li Sun, Li Huang, Fang Wang, Xiqian Zhang & Fenghua Liu. (2021) Fixed Gonadotropin-Releasing Hormone Antagonist Protocol Versus Flexible Progestin-Primed Ovarian Stimulation Protocol in Patients With Asynchronous Follicular Development During Controlled Ovulation Stimulation: A Retrospective Study. Frontiers in Endocrinology 12.
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Muhjah Falah Hassan, Pallav Sengupta & Sulagna Dutta. (2021) Assisted Reproductive Technologies for Women with Polycystic Ovarian Syndrome. Biomedical and Pharmacology Journal 14:3, pages 1305-1308.
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Wanlin Zhang, Duo Xie, Hengde Zhang, Jianlei Huang, Xifeng Xiao, Binrong Wang, Yafei Tong, Ye Miao & Xiaohong Wang. (2020) Cumulative Live Birth Rates After the First ART Cycle Using Flexible GnRH Antagonist Protocol vs. Standard Long GnRH Agonist Protocol: A Retrospective Cohort Study in Women of Different Ages and Various Ovarian Reserve. Frontiers in Endocrinology 11.
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Wan Yang, Rui Yang, Mingmei Lin, Yan Yang, Xueling Song, Jiajia Zhang, Shuo Yang, Ying Song, Jia Li, Tianshu Pang, Feng Deng, Hua Zhang, Ying Wang, Rong Li & Jie Jiao. (2018) Body mass index and basal androstenedione are independent risk factors for miscarriage in polycystic ovary syndrome. Reproductive Biology and Endocrinology 16:1.
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Lionel Carbillon, Heloise Gronier, Isabelle Cedrin-Durnerin, Isabelle Pharisien, Minh T. Nguyen, Paul Valensi & Emmanuel Cosson. (2017) The impact of ovulation induction and ovarian stimulation on the risk of pregnancy-induced hypertension and on neonatal outcomes: A case/control study. European Journal of Obstetrics & Gynecology and Reproductive Biology 217, pages 137-143.
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Shutian Jiang & Yanping Kuang. (2017) Clomiphene citrate is associated with favorable cycle characteristics but impaired outcomes of obese women with polycystic ovarian syndrome undergoing ovarian stimulation for in vitro fertilization. Medicine 96:32, pages e7540.
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Xiang-Hong Zhai, Ping Zhang, Feng-Xia Wu, An-Cong Wang & Pei-Shu Liu. (2017) GnRH antagonist for patients with polycystic ovary syndrome undergoing controlled ovarian hyperstimulation for in vitro fertilization and embryo transfer in fresh cycles. Experimental and Therapeutic Medicine 13:6, pages 3097-3102.
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Annick Delvigne. 2017. Complications and Outcomes of Assisted Reproduction. Complications and Outcomes of Assisted Reproduction 124 140 .
Weijie Xing, Haiyan Lin & Qingxue Zhang. (2017) GnRH Antagonist Protocol: Is It Optimal for All Patients of Different Ages Undergoing <i>In Vitro</i> Fertilization and Embryo Transfer?. Advances in Sexual Medicine 07:04, pages 153-160.
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Byung-Chul Jee. 2017. Development of In Vitro Maturation for Human Oocytes. Development of In Vitro Maturation for Human Oocytes 175 184 .
Samantha Pfeifer, Samantha Butts, Daniel Dumesic, Gregory Fossum, Clarisa Gracia, Andrew La Barbera, Jennifer Mersereau, Randall Odem, Richard Paulson, Alan Penzias, Margareta Pisarska, Robert Rebar, Richard Reindollar, Mitchell Rosen, Jay Sandlow, Michael Vernon & Eric Widra. (2016) Prevention and treatment of moderate and severe ovarian hyperstimulation syndrome: a guideline. Fertility and Sterility 106:7, pages 1634-1647.
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M. Kollmann, W. P. Martins, M. L. S. Lima, L. Craciunas, C. O. Nastri, A. Richardson & N. Raine-Fenning. (2016) Strategies for improving outcome of assisted reproduction in women with polycystic ovary syndrome: systematic review and meta-analysis. Ultrasound in Obstetrics & Gynecology 48:6, pages 709-718.
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. (2016) Fresh versus Frozen Embryos in Polycystic Ovary Syndrome. New England Journal of Medicine 375:20, pages e42.
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Anderson Sanches Melo, Rui Alberto Ferriani & Paula Andrea Navarro. (2015) Treatment of infertility in women with polycystic ovary syndrome: approach to clinical practice. Clinics 70:11, pages 765-769.
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Samer Tannus, Yechiel Z Burke & Shahar Kol. (2015) Treatment Strategies for the Infertile Polycystic Ovary Syndrome Patient. Women's Health 11:6, pages 901-912.
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B. Özmen, Y.E. Şükür, M.M. Seval, C. Ateş, C.S. Atabekoğlu, M. Sönmezer & B. Berker. (2014) Dual suppression with oral contraceptive pills in GnRH antagonist cycles for patients with polycystic ovary syndrome undergoing intracytoplasmic sperm injection. European Journal of Obstetrics & Gynecology and Reproductive Biology 183, pages 137-140.
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Jin-song Xiao, Cun-mei Su & Xian-tao Zeng. (2014) Comparisons of GnRH Antagonist versus GnRH Agonist Protocol in Supposed Normal Ovarian Responders Undergoing IVF: A Systematic Review and Meta-Analysis. PLoS ONE 9:9, pages e106854.
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Haiyan Lin, Yu Li, Lin Li, Wenjun Wang, Dongzi Yang & Qingxue Zhang. (2014) Is a GnRH Antagonist Protocol Better in PCOS Patients? A Meta-Analysis of RCTs. PLoS ONE 9:3, pages e91796.
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Paul R. Brezina, Virginia Mensah, Adam Balen, Milton Leong, Ariel Weissman, Yulian Zhao & Zeev Shoham. (2013) Fertility management in the PCOS population: results of a web-based survey at IVF-worldwide.com. Journal of Assisted Reproduction and Genetics 30:9, pages 1169-1174.
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