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Original Article

Low platelet disaggregation predicts poor response to 150 mg clopidogrel in patients with elevated platelet reactivity

, MD, , , &
Pages 1-10 | Received 17 Sep 2009, Accepted 06 Oct 2009, Published online: 23 Nov 2009

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K. A. L. Müller, A. Karathanos, E. Tavlaki, F. Stimpfle, M. Meissner, B. Bigalke, K. Stellos, M. Schwab, E. Schaeffeler, I. I. Müller, M. Gawaz & T. Geisler. (2014) Combination of high on-treatment platelet aggregation and low deaggregation better predicts long-term cardiovascular events in PCI patients under dual antiplatelet therapy. Platelets 25:6, pages 439-446.
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Dániel Aradi & András Komócsi. (2012) Platelet function monitoring in patients on clopidogrel: What should we learn from GRAVITAS?. Platelets 23:3, pages 167-176.
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Articles from other publishers (8)

Christina C. Rolling, Julia Tomada, Andreas M. Frölich, Brigitte Holst, Katharina Holstein, Minna Voigtländer, Snjezana Janjetovic, Munif Haddad, Thomas Renné, Jens Fiehler, Carsten Bokemeyer, Thierry Rolling & Florian Langer. (2021) Comparison of acetylsalicylic acid and clopidogrel non-responsiveness assessed by light transmittance aggregometry and PFA-100 ® in patients undergoing neuroendovascular procedures . Clinical Chemistry and Laboratory Medicine (CCLM) 59:2, pages 383-392.
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Patricia P. Wadowski, Beate Eichelberger, Christoph W. Kopp, Joseph Pultar, Daniela Seidinger, Renate Koppensteiner, Irene M. Lang, Simon Panzer & Thomas Gremmel. (2017) Disaggregation Following Agonist-Induced Platelet Activation in Patients on Dual Antiplatelet Therapy. Journal of Cardiovascular Translational Research 10:4, pages 359-367.
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Christos Christopoulos, Mohamed Farag, Keith Sullivan, David Wellsted & Diana A. Gorog. (2017) Impaired thrombolytic status predicts adverse cardiac events in patients undergoing primary percutaneous coronary intervention. Thrombosis and Haemostasis 117:03, pages 457-470.
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Nazish Khan, Anthony R. Cox & James M. Cotton. (2016) Pharmacokinetics and pharmacodynamics of oral P2Y12 inhibitors during the acute phase of a myocardial infarction: A systematic review. Thrombosis Research 143, pages 141-148.
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Sarolta Leé, Katarina Vargová, István Hizoh, Zsófia Horváth, Petra Gulácsi-Bárdos, Zsófia Sztupinszki, Anna Apró, Andrea Kovács, István Préda, Emese Tóth-Zsámboki & Róbert G. Kiss. (2014) High on clopidogrel treatment platelet reactivity is frequent in acute and rare in elective stenting and can be functionally overcome by switch of therapy. Thrombosis Research 133:2, pages 257-264.
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Dániel Aradi, Orsolya Rideg, András Vorobcsuk, Tamás Magyarlaki, Balázs Magyari, Attila Kónyi, Tünde Pintér, Iván G. Horváth & András Komócsi. (2011) Justification of 150 mg clopidogrel in patients with high on‐clopidogrel platelet reactivity. European Journal of Clinical Investigation 42:4, pages 384-392.
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Nora Mallouk, Carine Labruyère, Jean-Luc Reny, Céline Chapelle, Michèle Piot, Pierre Fontana, Jean-Christophe Gris, Xavier Delavenne, Patrick Mismetti & Silvy Laporte. (2017) Prevalence of poor biological response to clopidogrel. Thrombosis and Haemostasis 107:03, pages 494-506.
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Dániel Aradi, Orsolya Rideg & András Komócsi. (2011) Platelet function monitoring in patients on clopidogrel. Interventional Medicine and Applied Science 3:1, pages 32-38.
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