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Research Article

Development and validation of a production process of platelet lysate for autologous use

, , , PhD, &
Pages 204-209 | Received 16 Jun 2010, Accepted 08 Oct 2010, Published online: 15 Dec 2010

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Natalie Fekete, Mélanie Gadelorge, Daniel Fürst, Caroline Maurer, Julia Dausend, Sandrine Fleury-Cappellesso, Volker Mailänder, Ramin Lotfi, Anita Ignatius, Luc Sensebé, Philippe Bourin, Hubert Schrezenmeier & Markus Thomas Rojewski. (2012) Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: production process, content and identification of active components. Cytotherapy 14:5, pages 540-554.
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Articles from other publishers (19)

Ying-Hao Wen, Chen-Fang Lee, Yu-Ju Chen, Gwo-Jyh Chang & Kowit-Yu Chong. (2022) Risks in Induction of Platelet Aggregation and Enhanced Blood Clot Formation in Platelet Lysate Therapy: A Pilot Study. Journal of Clinical Medicine 11:14, pages 3972.
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Luciana Y. Daikuara, Xifang Chen, Zhilian Yue, Danielle Skropeta, Fiona M. Wood, Mark W. Fear & Gordon G. Wallace. (2021) 3D Bioprinting Constructs to Facilitate Skin Regeneration. Advanced Functional Materials 32:3, pages 2105080.
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Luciana Y. Daikuara, Zhilian Yue, Danielle Skropeta & Gordon G. Wallace. (2021) In vitro characterisation of 3D printed platelet lysate-based bioink for potential application in skin tissue engineering. Acta Biomaterialia 123, pages 286-297.
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Alejandra E. Rodríguez & Jorge L. Alió. 2019. Corneal Regeneration. Corneal Regeneration 317 345 .
Ioanna Christou, Panagiotis Mallis, Efstathios Michalopoulos, Theofanis Chatzistamatiou, George Mermelekas, Jerome Zoidakis, Antonia Vlahou & Catherine Stavropoulos-Giokas. (2018) Evaluation of Peripheral Blood and Cord Blood Platelet Lysates in Isolation and Expansion of Multipotent Mesenchymal Stromal Cells. Bioengineering 5:1, pages 19.
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Scarlett M. Sumner, Maria C. Naskou, Merrilee Thoresen, Ian Copland & John F. Peroni. (2017) Platelet lysate obtained via plateletpheresis performed in standing and awake equine donors. Transfusion 57:7, pages 1755-1762.
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Antonio Barile, Alice La Marra, Francesco Arrigoni, Silvia Mariani, Luigi Zugaro, Alessandra Splendiani, Ernesto Di Cesare, Alfonso Reginelli, Marcello Zappia, Luca Brunese, Ejona Duka, Giampaolo Carrafiello & Carlo Masciocchi. (2016) Anaesthetics, steroids and platelet-rich plasma (PRP) in ultrasound-guided musculoskeletal procedures. The British Journal of Radiology 89:1065, pages 20150355.
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Chengbo Tan, Hideo Shichinohe, Zifeng Wang, Shuji Hamauchi, Takeo Abumiya, Naoki Nakayama, Ken Kazumata, Tsuneo Ito, Kohsuke Kudo, Shigeru Takamoto & Kiyohiro Houkin. (2016) Feasibility and Efficiency of Human Bone Marrow Stromal Cell Culture with Allogeneic Platelet Lysate-Supplementation for Cell Therapy against Stroke. Stem Cells International 2016, pages 1-11.
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John Peroni & Lindsey Boone. 2015. Stem Cells in Regenerative Medicine. Stem Cells in Regenerative Medicine 257 274 .
F. Hildner, M. J. Eder, K. Hofer, J. Aberl, H. Redl, M. van Griensven, C. Gabriel & A. Peterbauer-Scherb. (2015) Human platelet lysate successfully promotes proliferation and subsequent chondrogenic differentiation of adipose-derived stem cells: a comparison with articular chondrocytes. Journal of Tissue Engineering and Regenerative Medicine 9:7, pages 808-818.
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Pablo Hofbauer, Sabrina Riedl, Karin Witzeneder, Florian Hildner, Susanne Wolbank, Marion Groeger, Christian Gabriel, Heinz Redl & Wolfgang Holnthoner. (2014) Human platelet lysate is a feasible candidate to replace fetal calf serum as medium supplement for blood vascular and lymphatic endothelial cells. Cytotherapy 16:9, pages 1238-1244.
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C. Gabriel. (2014) How to establish and run a cell therapy unit in a blood bank. ISBT Science Series 9:1, pages 155-159.
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Javier Ramos-Torrecillas, Elvira de Luna-Bertos, Francisco J. Manzano-Moreno, Olga García-Martínez & Concepción Ruiz. (2014) Human Fibroblast–Like Cultures in the Presence of Platelet-Rich Plasma as a Single Growth Factor Source. Advances in Skin & Wound Care 27:3, pages 114-120.
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Javier Ramos-Torrecillas, E. De Luna-Bertos, O. García-Martínez, L. Díaz-Rodríguez & C. Ruiz. (2013) Use of Platelet-Rich Plasma to Treat Pressure Ulcers. Journal of Wound, Ostomy & Continence Nursing 40:2, pages 198-202.
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Patrick H. Warnke, Andreas Humpe, Dirk Strunk, Sebastien Stephens, Frauke Warnke, Joerg Wiltfang, Katharina Schallmoser, Mohammad Alamein, Robert Bourke, Peter Heiner & Qin Liu. (2013) A clinically-feasible protocol for using human platelet lysate and mesenchymal stem cells in regenerative therapies. Journal of Cranio-Maxillofacial Surgery 41:2, pages 153-161.
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Karin Witzeneder, Andrea Lindenmair, Christian Gabriel, Katharina Höller, Denise Theiß, Heinz Redl & Simone Hennerbichler. (2013) Human-Derived Alternatives to Fetal Bovine Serum in Cell Culture. Transfusion Medicine and Hemotherapy 40:6, pages 417-423.
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B. DUNKEL, D. M. BOLT, R. K. SMITH & F. M. CUNNINGHAM. (2012) Stimulus-dependent release of tissue-regenerating factors by equine platelets. Equine Veterinary Journal 44:3, pages 346-354.
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B. A. Naaijkens, H. W. M. Niessen, H-J. Prins, P. A. J. Krijnen, T. J. A. Kokhuis, N. de Jong, V. W. M. van Hinsbergh, O. Kamp, M. N. Helder, R. J. P. Musters, A. van Dijk & L. J. M. Juffermans. (2012) Human platelet lysate as a fetal bovine serum substitute improves human adipose-derived stromal cell culture for future cardiac repair applications. Cell and Tissue Research 348:1, pages 119-130.
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Li-Cheng Wei, Shu-Guang Gao, Mai Xu, Wei Jiang, Jian Tian & Guang-Hua Lei. (2012) A novel hypothesis: The application of platelet-rich plasma can promote the clinical healing of white-white meniscal tears. Medical Science Monitor 18:8, pages HY47-HY50.
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