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Original Article

Dextran sulfate triggers platelet aggregation via direct activation of PEAR1

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Pages 365-372 | Received 30 Sep 2015, Accepted 13 Oct 2015, Published online: 30 Nov 2015

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Narges Ansari, Sahar Najafi, Saied Shahrabi & Najmaldin Saki. (2020) PEAR1 polymorphisms as a prognostic factor in hemostasis and cardiovascular diseases. Journal of Thrombosis and Thrombolysis 51:1, pages 89-95.
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Joshua P. Lewis, Moeen Riaz, Sophia Xie, Galina Polekhina, Rory Wolfe, Mark Nelson, Andrew M. Tonkin, Christopher M. Reid, Anne M. Murray, John J. McNeil, Alan R. Shuldiner & Paul Lacaze. (2020) Genetic Variation in PEAR1, Cardiovascular Outcomes and Effects of Aspirin in a Healthy Elderly Population. Clinical Pharmacology & Therapeutics 108:6, pages 1289-1298.
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Benedetta Izzi, Francesco Gianfagna, Wen-Yi Yang, Katrien Cludts, Amalia De Curtis, Peter Verhamme, Augusto Di Castelnuovo, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Jan A. Staessen, Marc F. Hoylaerts & Licia Iacoviello. (2019) Variation of PEAR1 DNA methylation influences platelet and leukocyte function. Clinical Epigenetics 11:1.
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Yongjian Yue, Shengguo Liu, Xuemei Han, Minlian Wang, Yazhen Li, Qijun Huang, Bo Li, Mo Yang, Yong Dai & Yingyun Fu. (2019) iTRAQ‐based proteomic analysis of human umbilical vein endothelial cells with platelet endothelial aggregation receptor‐1 knockdown. Journal of Cellular Biochemistry 120:8, pages 12300-12310.
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Caroline Kardeby, Knut Fälker, Elizabeth J. Haining, Maarten CrielMadelene LindkvistRuben BarrosoPeter Påhlsson, Liza U. LjungbergMattias TengdeliusG. Ed RaingerStephanie WatsonJohannes A. Eble, Marc F. HoylaertsJonas Emsley, Peter KonradssonSteve P. WatsonYi SunMagnus Grenegård. (2019) Synthetic glycopolymers and natural fucoidans cause human platelet aggregation via PEAR1 and GPIbα. Blood Advances 3:3, pages 275-287.
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Alexander P. Reiner & Andrew D. Johnson. 2019. Platelets. Platelets 99 126 .
Fabian Stimpfle, Maike Bauer, Dominik Rath, Elke Schaeffeler, Matthias Schwab, Meinrad Gawaz, Stefan Winter & Tobias Geisler. (2018) Variants of PEAR1 Are Associated With Outcome in Patients With ACS and Stable CAD Undergoing PCI. Frontiers in Pharmacology 9.
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Benedetta Izzi, Fabrizia Noro, Katrien Cludts, Kathleen Freson & Marc Hoylaerts. (2018) Cell-Specific PEAR1 Methylation Studies Reveal a Locus that Coordinates Expression of Multiple Genes. International Journal of Molecular Sciences 19:4, pages 1069.
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