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International Review of Psychiatry Volume 25, 2013 - Issue 5: Future roles of pharmacogenomic testing and Biomarkers in Psychiatry. GUEST EDITORS: Daniel J. Müller, James L. Kennedy and Hubertus Himmerich
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Research Article

The value of drug and metabolite concentration in blood as a biomarker of psychopharmacological therapy

Gudrun HefnerDepartment of Psychiatry and Psychotherapy, University Medical Centre Mainz, Germany
,
A. Kathrin LaibDepartment of Psychiatry and Psychotherapy, University Medical Centre Mainz, Germany
,
Hilmar SigurdssonDepartment of Psychiatry and Psychotherapy, University Medical Centre Mainz, Germany
,
Matthias HohnerDepartment of Psychiatry and Psychotherapy, University Medical Centre Mainz, Germany
&
Christoph HiemkeDepartment of Psychiatry and Psychotherapy, University Medical Centre Mainz, GermanyCorrespondence[email protected]
Pages 494-508 | Received 24 May 2013, Accepted 16 Aug 2013, Published online: 23 Oct 2013

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Edoardo Spina, Christoph Hiemke & Jose de Leon. (2016) Assessing drug-drug interactions through therapeutic drug monitoring when administering oral second-generation antipsychotics. Expert Opinion on Drug Metabolism & Toxicology 12:4, pages 407-422.
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Articles from other publishers (16)

Cleo S. M. Funk, Xenia M. Hart, Gerhard Gründer, Christoph Hiemke, Björn Elsner, Reinhold Kreutz & Thomas G. Riemer. (2022) Is Therapeutic Drug Monitoring Relevant for Antidepressant Drug Therapy? Implications From a Systematic Review and Meta-Analysis With Focus on Moderating Factors. Frontiers in Psychiatry 13.
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Antonio F. Pardiñas, Michael J. Owen & James T.R. Walters. (2021) Pharmacogenomics: A road ahead for precision medicine in psychiatry. Neuron 109:24, pages 3914-3929.
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Yuan-Yuan Zhang, Xie-Hai Zhou, Feng Shan & Jun Liang. (2021) Infection is associated with elevated serum concentrations of antipsychotic drugs. International Clinical Psychopharmacology 36:5, pages 264-267.
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Lennart Kyllesø, Robert Løvsletten Smith, Øystein Karlstad, Ole A. Andreassen & Espen Molden. (2021) Absolute and Dose-Adjusted Serum Concentrations of Clozapine in Patients Switching vs. Maintaining Treatment: An Observational Study of 1979 Patients. CNS Drugs 35:9, pages 999-1008.
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Nicole Moschny, Gudrun Hefner, Renate Grohmann, Gabriel Eckermann, Hannah B Maier, Johanna Seifert, Johannes Heck, Flverly Francis, Stefan Bleich, Sermin Toto & Catharina Meissner. (2021) Therapeutic Drug Monitoring of Second- and Third-Generation Antipsychotic Drugs—Influence of Smoking Behavior and Inflammation on Pharmacokinetics. Pharmaceuticals 14:6, pages 514.
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Sermin Toto, Gudrun Hefner, Martina Hahn, Christoph Hiemke, Sibylle C. Roll, Jan Wolff & Ansgar Klimke. (2021) Current use of anticholinergic medications in a large naturalistic sample of psychiatric patients. Journal of Neural Transmission 128:2, pages 263-272.
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Gudrun Hefner, Martina Hahn, Christoph Hiemke, Sermin Toto, Jan Wolff, Sibylle C. Roll & Ansgar Klimke. (2021) Pharmacodynamic Drug–Drug interactions of QT-prolonging drugs in hospitalized psychiatric patients. Journal of Neural Transmission 128:2, pages 243-252.
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Michel Bourin. 2021. Psychiatry and Neuroscience Update. Psychiatry and Neuroscience Update 647 660 .
Jin H. Han, Alex Chen, Eduard E. Vasilevskis, John F. Schnelle, E. Wesley Ely, Rameela Chandrasekhar, Ryan D. Morrison, Timothy P. Ryan, J. Scott Daniels, Jeff J. Sutherland & Sandra F. Simmons. (2019) Supratherapeutic Psychotropic Drug Levels in the Emergency Department and Their Association with Delirium Duration: A Preliminary Study. Journal of the American Geriatrics Society 67:11, pages 2387-2392.
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Timothy P. Ryan, Ryan D. Morrison, Jeffrey J. Sutherland, Stephen B. Milne, Kendall A. Ryan, J. Scott Daniels, Anita Misra-Hebert, J. Kevin Hicks, Eric Vogan, Kathryn Teng & Thomas M. Daly. (2017) Medication adherence, medical record accuracy, and medication exposure in real-world patients using comprehensive medication monitoring. PLOS ONE 12:9, pages e0185471.
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Christoph Hiemke & Gudrun Hefner. 2017. Altersdepression. Altersdepression 121 139 .
Gudrun Hefner, Mohamed E. E. Shams, Stefan Unterecker, Tanja Falter & Christoph Hiemke. (2015) Inflammation and psychotropic drugs: the relationship between C-reactive protein and antipsychotic drug levels. Psychopharmacology 233:9, pages 1695-1705.
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Christoph Hiemke & Ekkehard Haen. 2016. Pharmacovigilance in Psychiatry. Pharmacovigilance in Psychiatry 95 119 .
Jin Lu, Lili Wan, Yuan Zhong, Qi Yu, Yonglong Han, Pengguo Chen, Beiyun Wang, Wei Li, Ya Miao & Cheng Guo. (2015) Stereoselective metabolism of donepezil and steady-state plasma concentrations of S-donepezil based on CYP2D6 polymorphisms in the therapeutic responses of Han Chinese patients with Alzheimer's disease. Journal of Pharmacological Sciences 129:3, pages 188-195.
Crossref
Christoph Hiemke. 2010. Encyclopedia of Psychopharmacology. Encyclopedia of Psychopharmacology 1 11 .
Martijn Arns & Sebastian Olbrich. 2014. Electrophysiology and Psychophysiology in Psychiatry and Psychopharmacology. Electrophysiology and Psychophysiology in Psychiatry and Psychopharmacology 345 370 .

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