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Journal of Dermatological Treatment Volume 23, 2012 - Issue 5
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Clinical investigations and reports

Curcuma aeruginosa, a novel botanically derived 5α-reductase inhibitor in the treatment of male-pattern baldness: a multicenter, randomized, double-blind, placebo-controlled study

Ganniga Pumthong Cosmetic and Natural Product Research Center, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand
,
Pravit Asawanonda Division of Dermatology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
,
Supenya Varothai Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
,
Vorapicha Jariyasethavong Division of Dermatology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
,
Daranporn Triwongwaranat Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
,
Puan Suthipinittharm College of Medicine and Public Health, Ubon Ratchathani University, Warin Chamrap, Thailand
,
Kornkanok Ingkaninan Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand
,
Pimporn Leelapornpisit Faculty of Pharmaceutical Sciences, Chiang Mai University, Chiang Mai, Thailand
&
Neti Waranuch Cosmetic and Natural Product Research Center, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, ThailandCorrespondence[email protected]
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Pages 385-392 | Received 08 Dec 2010, Accepted 07 Feb 2011, Published online: 14 Jul 2011

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Ajaikumar B. Kunnumakkara, Choudhary Harsha, Kishore Banik, Rajesh Vikkurthi, Bethsebie L. Sailo, Devivasha Bordoloi, Subash C. Gupta & Bharat B. Aggarwal. (2019) Is curcumin bioavailability a problem in humans: lessons from clinical trials. Expert Opinion on Drug Metabolism & Toxicology 15:9, pages 705-733.
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Articles from other publishers (26)

Kelly O’Connor & Lynne J. Goldberg. 2024. Procedures in Cosmetic Dermatology: Hair Restoration. Procedures in Cosmetic Dermatology: Hair Restoration 45 60 .
Peter R. Feldman, Pietro Gentile, Charles Piwko, Hendrik M. Motswaledi, Samantha Gorun, Jacob Pesachov, Michael Markel, Maxwell I. Silver, Megan Brenkel, Oriel J. Feldman, Corey L. Kamen, Elizabeth Uleryk, Jaime Guevara-Aguirre & Klaus M. Fiebig. (2023) Hair regrowth treatment efficacy and resistance in androgenetic alopecia: A systematic review and continuous Bayesian network meta-analysis. Frontiers in Medicine 9.
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Aditya K. Gupta, Tong Wang, Mary A. Bamimore, Shruthi Polla Ravi & Mesbah Talukder. (2023) Relative Effects of Minoxidil 5%, Platelet-Rich Plasma, and Microneedling in Pattern Hair Loss: A Systematic Review and Network Meta-Analysis. Skin Appendage Disorders 9:6, pages 397-406.
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Alaa YoussefDalia A. Al-MahdyRabab H. SayedMouchira A. ChoucryHesham El-Askary. (2022) A Comprehensive Review of Natural Alternatives for Treatment of Alopecia with an Overview of Market Products. Journal of Medicinal Food 25:9, pages 869-881.
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Chandramohan MarimuthuJaya Ganesh MuruganSruthi SukumarPriya Rajendran. (2022) Effects on Oral Supplementation of Nutraceuticals formulations - Trichovitals® in young adults for healthy maintenance of hair growth. Research Journal of Topical and Cosmetic Sciences, pages 1-8.
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Konstantinos AnastassakisKonstantinos Anastassakis. 2022. Androgenetic Alopecia From A to Z. Androgenetic Alopecia From A to Z 507 519 .
SANG-HWAN DO, RYUN-SUP AHN, MYUNG-SUK NA & HYUNG-RUEL JU. (2021) IMPROVEMENT OF ALOPECIA AND DECREASES IN HAIR CORTISOL AND DIHYDROTESTOSTERONE CONCENTRATIONS AFTER THE TOPICAL USE OF PLANT EXTRACTS IN MEN WITH ANDROGENETIC ALOPECIA. Asian Journal of Pharmaceutical and Clinical Research, pages 71-79.
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Sanusi Umar & Marissa J. Carter. (2021) A Multimodal Hair-Loss Treatment Strategy Using a New Topical Phytoactive Formulation: A Report of Five Cases. Case Reports in Dermatological Medicine 2021, pages 1-12.
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Sarana Rose Sommano & Tibet Tangpao. 2021. Aromatic Herbs in Food. Aromatic Herbs in Food 123 165 .
Giorgio Dell’Acqua, Aleksander Richards & M. Julie Thornton. (2020) The Potential Role of Nutraceuticals as an Adjuvant in Breast Cancer Patients to Prevent Hair Loss Induced by Endocrine Therapy. Nutrients 12:11, pages 3537.
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Ana Zgonc Škulj, Nina Poljšak, Nina Kočevar Glavač & Samo Kreft. (2019) Herbal preparations for the treatment of hair loss. Archives of Dermatological Research 312:6, pages 395-406.
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Aditya K. Gupta, Rachel R. Mays, Sarah G. Versteeg, Neil H. Shear, Vincent Piguet & Bianca Maria Piraccini. (2019) Efficacy of Off-Label Topical Treatments for the Management of Androgenetic Alopecia: A Review. Clinical Drug Investigation 39:3, pages 233-239.
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Nicholas John Sadgrove. (2018) The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-reductase inhibition, reversal of secondary microinflammation and improving insulin resistance. Journal of Ethnopharmacology 227, pages 206-236.
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Noura Dosoky & William Setzer. (2018) Chemical Composition and Biological Activities of Essential Oils of Curcuma Species. Nutrients 10:9, pages 1196.
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Jukkarin Srivilai, Neti Waranuch, Anothai Tangsumranjit, Nantaka Khorana & Kornkanok Ingkaninan. (2017) Germacrone and sesquiterpene-enriched extracts from Curcuma aeruginosa Roxb. increase skin penetration of minoxidil, a hair growth promoter. Drug Delivery and Translational Research 8:1, pages 140-149.
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Jukkarin Srivilai, Kanjana  Nontakhot, Thanawan Nutuan, Neti Waranuch, Nantaka Khorana, Wudtichai Wisuthiprot, C. Norman Scholfield, Katechan Champachaisri & Kornkanok Ingkaninan. (2018) Sesquiterpene-Enriched Extract of <b><i>Curcuma aeruginosa</i></b> Roxb. Retards Axillary Hair Growth: A Randomised, Placebo-Controlled, Double-Blind Study. Skin Pharmacology and Physiology 31:2, pages 99-106.
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V. Kanti, A. Messenger, G. Dobos, P. Reygagne, A. Finner, A. Blumeyer, M. Trakatelli, A. Tosti, V. del Marmol, B.M. Piraccini, A. Nast & U. Blume‐Peytavi. (2017) Evidence‐based (S3) guideline for the treatment of androgenetic alopecia in women and in men – short version. Journal of the European Academy of Dermatology and Venereology 32:1, pages 11-22.
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Anna Herman & Andrzej P. Herman. (2017) Topically used herbal products for the treatment of hair loss: preclinical and clinical studies. Archives of Dermatological Research 309:8, pages 595-610.
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Gurkan Yardimci. 2017. Hair and Scalp Disorders. Hair and Scalp Disorders.
Jukkarin Srivilai, Preeyawass Phimnuan, Jiraporn Jaisabai, Nantakarn Luangtoomma, Neti Waranuch, Nantaka Khorana, Wudtichai Wisuitiprot, C. Norman Scholfield, Katechan Champachaisri & Kornkanok Ingkaninan. (2017) Curcuma aeruginosa Roxb. essential oil slows hair-growth and lightens skin in axillae; a randomised, double blinded trial. Phytomedicine 25, pages 29-38.
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Jukkarin Srivilai, Nantaka Khorana, Neti Waranuch, Wudtichai Wisuitiprot, Nungruthai Suphrom, Apichart Suksamrarn & Kornkanok Ingkaninan. (2016) Germacrene Analogs are Anti-androgenic on Androgen-dependent Cells. Natural Product Communications 11:9, pages 1934578X1601100.
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Alexandra R. Vaughn, Amy Branum & Raja K. Sivamani. (2016) Effects of Turmeric ( Curcuma longa ) on Skin Health: A Systematic Review of the Clinical Evidence . Phytotherapy Research 30:8, pages 1243-1264.
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Seeun Park, Sedef Erdogan, Dahyun Hwang, Seonwook Hwang, Eun Hye HanYoung-Hee Lim. (2016) Bee Venom Promotes Hair Growth in Association with Inhibiting 5α-Reductase Expression. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 39:6, pages 1060-1068.
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Nungruthai Suphrom, Jukkarin Srivilai, Ganniga Pumthong, Nantaka Khorana, Neti Waranuch, Nanteetip Limpeanchob & Kornkanok Ingkaninan. (2014) Stability studies of antiandrogenic compounds in Curcuma aeruginosa  Roxb. extract . Journal of Pharmacy and Pharmacology 66:9, pages 1282-1293.
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Jukkarin Srivilai, Nantaka Khorana, Neti Waranuch, Nungruthai Suphrom & Kornkanok Ingkaninan. (2014) Conformational analysis of an anti-androgenic, (E,E)-8-hydroxygermacrene B, using NOESY and dynamic NMR spectroscopy. Bioorganic & Medicinal Chemistry Letters 24:15, pages 3526-3529.
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Supenya Varothai & Wilma F. Bergfeld. (2014) Androgenetic Alopecia: An Evidence-Based Treatment Update. American Journal of Clinical Dermatology 15:3, pages 217-230.
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