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International Journal of Radiation Biology Volume 86, 2010 - Issue 2
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RNA Interference of KU70 to Enhance Radiosensitivity

Lentivirus-mediated RNA interference of Ku70 to enhance radiosensitivity of human mammary epithelial cells

Veerle VandersickelDepartment of Basic Medical Sciences, Ghent University, Gent, Belgium
,
Monica ManciniDepartment of Structural and Functional Biology, Laboratory of Toxicology and Pharmacology, Università degli Studi dell’ Insubria, Busto Arsizio, Italy
,
Emanuela MarrasDepartment of Structural and Functional Biology, Laboratory of Toxicology and Pharmacology, Università degli Studi dell’ Insubria, Busto Arsizio, Italy
,
Petra WillemsDepartment of Basic Medical Sciences, Ghent University, Gent, Belgium
,
Jacobus SlabbertiThemba LABS, Somerset West, South Africa
,
Jan PhilippéDepartment of Clinical Biology, Microbiology and Immunology
,
Ellen DeschepperBiostatistics Unit, Ghent University, Gent, Belgium
,
Hubert ThierensDepartment of Basic Medical Sciences, Ghent University, Gent, Belgium
,
Gianpoalo PerlettiDepartment of Structural and Functional Biology, Laboratory of Toxicology and Pharmacology, Università degli Studi dell’ Insubria, Busto Arsizio, Italy
&
Anne VralDepartment of Basic Medical Sciences, Ghent University, Gent, BelgiumCorrespondence[email protected]
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Pages 114-124 | Received 11 Dec 2008, Accepted 09 Sep 2009, Published online: 11 Feb 2010

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Shaobin Wu, Xianwei Wang, Jin-Xiang Chen & Yuxiang Chen. (2014) Predictive factors for the sensitivity of radiotherapy and prognosis of esophageal squamous cell carcinoma. International Journal of Radiation Biology 90:5, pages 407-413.
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Articles from other publishers (10)

Miaomiao Zhang, Xiaopeng Guo, Yue Gao, Dong Lu & Wenjian Li. (2018) Tumor Cell–Accelerated Senescence Is Associated With DNA-PKcs Status and Telomere Dysfunction Induced by Radiation. Dose-Response 16:2, pages 155932581877152.
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Emad A. Ahmed, Eukene Vélaz, Michael Rosemann, Klaus-P. Gilbertz & Harry Scherthan. (2016) DNA repair kinetics in SCID mice Sertoli cells and DNA-PKcs-deficient mouse embryonic fibroblasts. Chromosoma 126:2, pages 287-298.
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HEPING ZHANG, JIANCHENG LI, WENFANG CHENG, DI LIU, CHENG CHEN, XIAOYING WANG, XUJING LU & XIFA ZHOU. (2015) RNA interference for epidermal growth factor receptor enhances the radiosensitivity of esophageal squamous cell carcinoma cell line Eca109. Oncology Letters 10:3, pages 1495-1500.
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Feng Ren, Zhu-lin Yang, Xingguo Tan, Dongcai Liu, Qiong Zou, Yuan Yuan, Jinghe Li, Lufeng Liang, Guixiang Zeng & Senlin Chen. (2014) DNA-PKcs and Ku70 are Predictive Markers for Poor Prognosis of Patients With Gall Bladder Malignancies. Applied Immunohistochemistry & Molecular Morphology 22:10, pages 741-747.
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Yuanyuan Wang, Xiaonan Chen, Xuanyu Hu, Ren Zhang, Yuwen Du, Wenqiao Zang, Ziming Dong & Guoqiang Zhao. (2014) Enhancement of silencing DNA polymerase β on the radiotherapeutic sensitivity of human esophageal carcinoma cell lines. Tumor Biology 35:10, pages 10067-10074.
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Jung Hun Oh, Harry P. Wong, Xiaowei Wang & Joseph O. Deasy. (2012) A Bioinformatics Filtering Strategy for Identifying Radiation Response Biomarker Candidates. PLoS ONE 7:6, pages e38870.
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Hideaki Ogiwara & Takashi Kohno. (2011) Essential Factors for Incompatible DNA End Joining at Chromosomal DNA Double Strand Breaks In Vivo. PLoS ONE 6:12, pages e28756.
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Veerle Vandersickel, Jacobus Slabbert, Hubert Thierens & Anne Vral. (2011) Comparison of the colony formation and crystal violet cell proliferation assays to determine cellular radiosensitivity in a repair-deficient MCF10A cell line. Radiation Measurements 46:1, pages 72-75.
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Veerle Vandersickel, Monica Mancini, Jacobus Slabbert, Emanuela Marras, Hubert Thierens, Gianpaolo Perletti & Anne Vral. (2010) The radiosensitizing effect of Ku70/80 knockdown in MCF10A cells irradiated with X-rays and p(66)+Be(40) neutrons. Radiation Oncology 5:1.
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Veerle VANDERSICKEL, Julie DEPUYDT, Bram VAN BOCKSTAELE, Gianpaolo PERLETTI, Jan PHILIPPE, Hubert THIERENS & Anne VRAL. (2010) Early Increase of Radiation-induced γH2AX Foci in a Human Ku70/80 Knockdown Cell Line Characterized by an Enhanced Radiosensitivity. Journal of Radiation Research 51:6, pages 633-641.
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