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International Journal of Radiation Biology Volume 88, 2012 - Issue 4
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P38 AND TGF-β1 IN IRRADIATED RAT ENTEROCYTES

Activation of p38 MAPK and expression of TGF-β1 in rat colon enterocytes after whole body γ-irradiation

Jaroslav PejchalCenter of Advanced Studies, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech RepublicCorrespondence[email protected]
,
Jakub NovotnýDepartment of Radiobiology, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic
,
Václav MařákDepartment of Radiobiology, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic
,
Jan ÖsterreicherDepartment of Radiobiology, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic
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Aleš TichýDepartment of Radiobiology, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic
,
Jiřina VávrováDepartment of Radiobiology, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic
,
Zuzana ŠinkorováDepartment of Radiobiology, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic
,
Lenka ZárybnickáDepartment of Radiobiology, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic
,
Eva NovotnáDepartment of Radiobiology, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic
,
Jaroslav ChládekDepartment of Farmacology, Faculty of Medicine in Hradec Králové, Charles University, Hradec Králové, Czech Republic
,
Andrea BabicováDepartment of Medical Biochemistry, Faculty of Medicine in Hradec Králové, Charles University, Hradec Králové, Czech Republic
,
Klára KubelkováCenter of Advanced Studies, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic
&
Kamil KučaCenter of Advanced Studies, Faculty of Military Health Sciences, University of Defence, Hradec Králové, Czech Republic
 show all
Pages 348-358 | Received 13 Jun 2011, Accepted 12 Dec 2011, Published online: 06 Feb 2012

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Jaroslav Pejchal, Zuzana Šinkorová, Aleš Tichý, Adéla Kmochová, Kamila Ďurišová, Klára Kubelková, Miroslav Pohanka, Jan Bureš, Ilja Tachecí, Kamil Kuča & Jiřina Vávrová. (2015) Attenuation of radiation-induced gastrointestinal damage by epidermal growth factor and bone marrow transplantation in mice. International Journal of Radiation Biology 91:9, pages 703-714.
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Articles from other publishers (18)

Jie-Fu Fan, Yang-Kai Wang, Min Liu, Guang-Sheng Liu, Tian-Jiao Min, Rui-Yong Chen & Ying He. (2023) Effect of angiotensin II on irradiation exacerbated decompression sickness. Scientific Reports 13:1.
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Natalia García-Flores, Jaime Jiménez-Suárez, Cristina Garnés-García, Diego M. Fernández-Aroca, Sebastia Sabater, Ignacio Andrés, Antonio Fernández-Aramburo, María José Ruiz-Hidalgo, Borja Belandia, Ricardo Sanchez-Prieto & Francisco J. Cimas. (2023) P38 MAPK and Radiotherapy: Foes or Friends?. Cancers 15:3, pages 861.
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Jana Zdarova Karasova, Jiri Kassa, Vendula Hepnarova, Jaroslav Pejchal, Lucie Junova, Rudolf Andrys, David Malinak, Petr Bzonek, Zuzana Kohoutova & Kamil Musilek. (2022) Toxicity, pharmacokinetics, and effectiveness of the ortho-chlorinated bispyridinium oxime, K870. Food and Chemical Toxicology 167, pages 113236.
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Jaroslav Pejchal, Ales Tichy, Adela Kmochova, Lenka Fikejzlova, Klara Kubelkova, Marcela Milanova, Anna Lierova, Alzbeta Filipova, Lubica Muckova & Jana Cizkova. (2022) Mitigation of Ionizing Radiation-Induced Gastrointestinal Damage by Insulin-Like Growth Factor-1 in Mice. Frontiers in Pharmacology 13.
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Jaroslav Pejchal, Petr Jošt, Lubica Múčková, Rudolf Andrýs, Miroslav Lísa & Jana Zdarova Karasova. (2022) A systematic evaluation of the cucurbit[7]uril pharmacokinetics and toxicity after a single dose and short-term repeated administration in mice. Archives of Toxicology 96:5, pages 1411-1421.
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Radek Sleha, Vera Radochova, Jiri Malis, Alexander Mikyska, Milan Houska, Karel Krofta, Katerina Bogdanova, Sylva Janovska, Jaroslav Pejchal, Milan Kolar, Pavel Cermak & Pavel Bostik. (2021) Strong Antimicrobial and Healing Effects of Beta-Acids from Hops in Methicillin-Resistant Staphylococcus aureus-Infected External Wounds In Vivo. Antibiotics 10:6, pages 708.
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Radek Sleha, Vera Radochova, Alexander Mikyska, Milan Houska, Radka Bolehovska, Sylva Janovska, Jaroslav Pejchal, Lubica Muckova, Pavel Cermak & Pavel Bostik. (2021) Strong Antimicrobial Effects of Xanthohumol and Beta-Acids from Hops against Clostridioides difficile Infection In Vivo. Antibiotics 10:4, pages 392.
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Jana Zdarova Karasova, Vendula Hepnarova, Rudolf Andrys, Miroslav Lisa, Petr Jost, Lubica Muckova, Jaroslav Pejchal, David Herman, Daniel Jun, Jiri Kassa & Kamil Kuca. (2020) Encapsulation of oxime K027 into cucurbit[7]uril: In vivo evaluation of safety, absorption, brain distribution and reactivation effectiveness. Toxicology Letters 320, pages 64-72.
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Vendula Hepnarova, Lubica Muckova, Avi Ring, Jaroslav Pejchal, David Herman, Jan Misik, Martina Hrabinova, Daniel Jun & Ondrej Soukup. (2019) Pharmacological and toxicological in vitro and in vivo effect of higher doses of oxime reactivators. Toxicology and Applied Pharmacology 383, pages 114776.
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Filip Caisberger, Jaroslav Pejchal, Jan Misik, Jiri Kassa, Martin Valis & Kamil Kuca. (2018) The benefit of combinations of oximes for the ability of antidotal treatment to counteract sarin-induced brain damage in rats. BMC Pharmacology and Toxicology 19:1.
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Darina Kohoutova, Jaroslav Pejchal & Jan Bures. (2018) Mitotic and apoptotic activity in colorectal neoplasia. BMC Gastroenterology 18:1.
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Jaroslav Pejchal, Jiří Kassa, Jan Misík & Jana Hatlapatková. (2017) Evaluation of soman-induced extracranial histopathology in the context of clinical biochemistry, mitotic and apoptotic activity and morphometric analysis. Journal of Applied Biomedicine 15:1, pages 23-31.
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Jaroslav Pejchal, Zuzana Sinkorova, Ales Tichy, Sarka Pruchova, Adela Kmochova, Kamila Durisova, Lucie Cechakova, Anna Lierova, Martin Ondrej, Marketa Nemcova, Klara Kubelkova, Ilona Fatorova, Jan Bures, Ilja Tacheci, Kamil Kuca & Jirina Vavrova. (2016) Epidermal Growth Factor Attenuates Delayed Ionizing Radiation-Induced Tissue Damage in Bone Marrow Transplanted Mice. Radiation Research 186:3, pages 264-274.
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Jian-Bo Lai, Chun-Fang Qiu, Chuan-Xi Chen, Min-Ying Chen, Juan Chen, Xiang-Dong Guan & Bin Ouyang. (2016) Inhibition of c-Jun N-terminal Kinase Signaling Pathway Alleviates Lipopolysaccharide-induced Acute Respiratory Distress Syndrome in Rats. Chinese Medical Journal 129:14, pages 1719-1724.
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Yanqing Zhang, Chenliang Deng, Jiang Qian, Mingui Zhang & Xiaofeng Li. (2014) Improvement of Radiotherapy-Induced Lacrimal Gland Injury by Induced Pluripotent Stem Cell-Derived Conditioned Medium via MDK and Inhibition of the p38/JNK Pathway. International Journal of Molecular Sciences 15:10, pages 18407-18421.
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Marjan Boerma, Junru Wang, Vijayalakshmi Sridharan, Jean-Marc Herbert & Martin Hauer-Jensen. (2013) Pharmacological Induction of Transforming Growth Factor-Beta1 in Rat Models Enhances Radiation Injury in the Intestine and the Heart. PLoS ONE 8:7, pages e70479.
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Miguel A. de la Cruz-Morcillo, Jesús García-Cano, Laura Arias-González, Elena García-Gil, Francisco Artacho-Cordón, Sandra Ríos-Arrabal, María L. Valero, Francisco J. Cimas, Leticia Serrano-Oviedo, María V. Villas, Jesús Romero-Fernández, María I. Núñez & Ricardo Sánchez-Prieto. (2013) Abrogation of the p38 MAPK α signaling pathway does not promote radioresistance but its activity is required for 5-Fluorouracil-associated radiosensitivity. Cancer Letters 335:1, pages 66-74.
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Jaroslav Pejchal, Jan Österreicher, Jiří Kassa, Václav Mařák, Aleš Tichý, Zuzana Šinkorová, Lenka Zárybnická, Klára Kubelková & Kamil Kuča. (2012) EFFECT OF SOMAN ON JNK AND P38 MITOGEN ACTIVATED PROTEIN KINASE (MAPK) PATHWAYS. Military Medical Science Letters 81:2, pages 68-75.
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