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Research Article

Long-term cognitive effects of human stem cell transplantation in the irradiated brain

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Pages 816-820 | Received 10 Mar 2014, Accepted 21 May 2014, Published online: 25 Jun 2014

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Ron J. Leavitt, Charles L. Limoli & Janet E. Baulch. (2019) miRNA-based therapeutic potential of stem cell-derived extracellular vesicles: a safe cell-free treatment to ameliorate radiation-induced brain injury. International Journal of Radiation Biology 95:4, pages 427-435.
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Dana Greene-Schloessor & Jacqueline P. Williams. (2014) Introduction to Michael E. Robbins Memorial Issue. International Journal of Radiation Biology 90:9, pages 729-730.
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Articles from other publishers (19)

Richard A. Britten & Charles L. Limoli. (2023) New Radiobiological Principles for the CNS Arising from Space Radiation Research. Life 13:6, pages 1293.
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Charles Limoli. (2020) Can a comparison of clinical and deep space irradiation scenarios shed light on the radiation response of the brain?. The British Journal of Radiology 93:1115, pages 20200245.
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Ron J. Leavitt, Munjal M. Acharya, Janet E. Baulch & Charles L. Limoli. (2020) Extracellular Vesicle–Derived miR-124 Resolves Radiation-Induced Brain Injury. Cancer Research 80:19, pages 4266-4277.
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Chengyan Chu, Yue Gao, Xiaoyan Lan, Jianwen Lin, Aline M. Thomas & Shen Li. (2020) Stem-Cell Therapy as a Potential Strategy for Radiation-Induced Brain Injury. Stem Cell Reviews and Reports 16:4, pages 639-649.
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Sarah M. Smith, Erich Giedzinski, Maria C. Angulo, Tiffany Lui, Celine Lu, Audrey L. Park, Sharon Tang, Vahan Martirosian, Ning Ru, Nicole N. Chmielewski, Yaxuan Liang, Janet E. Baulch, Munjal M. Acharya & Charles L. Limoli. (2020) Functional equivalence of stem cell and stem cell-derived extracellular vesicle transplantation to repair the irradiated brain. Stem Cells Translational Medicine 9:1, pages 93-105.
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Qixian Zhang, Xue Zhong, Jie Zhang, Hao Zhu, Shang Cai, Junjun Zhang, Yi Cao & Ye Tian. (2019) Integration of Neurons Derived from Transplanted BDNF-Overexpressing Neural Stem Cells into Circuit of the Irradiated Hippocampus. Radiation Research 192:3, pages 345.
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He Zuo & Huaidong Cheng. (2019) Research on the Mechanism of Radiation-Related Cognitive Impairment—A Review. Journal of Cancer Therapy 10:02, pages 188-196.
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Charles P. Hinzman, Janet E. Baulch, Khyati Y. Mehta, Kirandeep Gill, Charles L. Limoli & Amrita K. Cheema. (2018) Exposure to Ionizing Radiation Causes Endoplasmic Reticulum Stress in the Mouse Hippocampus. Radiation Research 190:5, pages 483.
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Sarah M. Smith & Charles L. Limoli. (2017) Stem Cell Therapies for the Resolution of Radiation Injury to the Brain. Current Stem Cell Reports 3:4, pages 342-347.
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Carmen Rios, Jean-René Jourdain & Andrea L. DiCarlo. (2017) Cellular Therapies for Treatment of Radiation Injury after a Mass Casualty Incident. Radiation Research 188:2, pages 242-245.
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Andrea L. DiCarlo, Radia Tamarat, Carmen I. Rios, Marc Benderitter, Christine W. Czarniecki, Theresa C. Allio, Francesca Macchiarini, Bert W. Maidment & Jean-Rene Jourdain. (2017) Cellular Therapies for Treatment of Radiation Injury: Report from a NIH/NIAID and IRSN Workshop. Radiation Research 188:2, pages e54-e75.
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Ethel Ngen & Dmitri Artemov. (2017) Advances in Monitoring Cell-Based Therapies with Magnetic Resonance Imaging: Future Perspectives. International Journal of Molecular Sciences 18:1, pages 198.
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Munjal M. Acharya, Kim N. Green, Barrett D. Allen, Allison R. Najafi, Amber Syage, Harutyun Minasyan, Mi T. Le, Takumi Kawashita, Erich Giedzinski, Vipan K. Parihar, Brian L. West, Janet E. Baulch & Charles L. Limoli. (2016) Elimination of microglia improves cognitive function following cranial irradiation. Scientific Reports 6:1.
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Munjal M. Acharya, Janet E. Baulch, Theresa A. Lusardi, Barrett. D. Allen, Nicole N. Chmielewski, Al Anoud D. Baddour, Charles L. Limoli & Detlev Boison. (2016) Adenosine Kinase Inhibition Protects against Cranial Radiation-Induced Cognitive Dysfunction. Frontiers in Molecular Neuroscience 9.
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Ethel J. Ngen, Lee Wang, Nishant Gandhi, Yoshinori Kato, Michael Armour, Wenlian Zhu, John Wong, Kathleen L. Gabrielson & Dmitri Artemov. (2016) A preclinical murine model for the early detection of radiation-induced brain injury using magnetic resonance imaging and behavioral tests for learning and memory: with applications for the evaluation of possible stem cell imaging agents and therapies. Journal of Neuro-Oncology 128:2, pages 225-233.
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Janet E. Baulch, Munjal M. Acharya, Barrett D. Allen, Ning Ru, Nicole N. Chmielewski, Vahan Martirosian, Erich Giedzinski, Amber Syage, Audrey L. Park, Sarah N. Benke, Vipan K. Parihar & Charles L. Limoli. (2016) Cranial grafting of stem cell-derived microvesicles improves cognition and reduces neuropathology in the irradiated brain. Proceedings of the National Academy of Sciences 113:17, pages 4836-4841.
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Gui-Hua Wang, Yang Liu, Xiao-Bing Wu, Ying Lu, Jin Liu, Ya-Ru Qin, Tong Li & Hai-Feng Duan. (2016) Neuroprotective effects of human umbilical cord–derived mesenchymal stromal cells combined with nimodipine against radiation-induced brain injury through inhibition of apoptosis. Cytotherapy 18:1, pages 53-64.
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Munjal M. Acharya, Susanna Rosi, Timothy Jopson & Charles L. Limoli. (2015) Human Neural Stem Cell Transplantation Provides Long-Term Restoration of Neuronal Plasticity in the Irradiated Hippocampus. Cell Transplantation 24:4, pages 691-702.
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Jae Ho KimKenneth A. JenrowStephen L. Brown. (2014) Mechanisms of radiation-induced normal tissue toxicity and implications for future clinical trials. Radiation Oncology Journal 32:3, pages 103.
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