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Research Article

Antioxidant Defense Mechanisms in Parasitic Protozoa

Pages 295-314 | Published online: 25 Sep 2008

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Keivan Adinehbeigi, Mohammad Hossein Razi Jalali, Ali Shahriari & Somayeh Bahrami. (2017) In vitro antileishmanial activity of fisetin flavonoid via inhibition of glutathione biosynthesis and arginase activity in Leishmania infantum. Pathogens and Global Health 111:4, pages 176-185.
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Michael P Barrett, Mireille Basselin & Graham H Coombs. (1998) Emerging therapeutic targets in parasitic protozoa. Emerging Therapeutic Targets 2:2, pages 57-85.
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V Udaya kumar, Muhammed Favas KT, Ayush Sharma, Priya Bisht, Sameer Dhingra, V. Ravichandiran, M. Ramesh & Krishna Murti. (2022) The Possible Role of Selected Vitamins and Minerals in the Therapeutic Outcomes of Leishmaniasis. Biological Trace Element Research 201:4, pages 1672-1688.
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Yasmin Pedra-Rezende, Ana Cristina Souza Bombaça & Rubem Figueiredo Sadok Menna-Barreto. (2022) Is the mitochondrion a promising drug target in trypanosomatids?. Memórias do Instituto Oswaldo Cruz 117.
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Manish T. Shrivastav, Zainab Malik & Somlata. (2021) Revisiting Drug Development Against the Neglected Tropical Disease, Amebiasis. Frontiers in Cellular and Infection Microbiology 10.
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Eva Horáková, Drahomíra Faktorová, Natalia Kraeva, Binnypreet Kaur, Jan Van Den Abbeele, Vyacheslav Yurchenko & Julius Lukeš. (2019) Catalase compromises the development of the insect and mammalian stages of Trypanosoma brucei . The FEBS Journal 287:5, pages 964-977.
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Laís Pessanha de Carvalho, Jana Held & Edésio José Tenório de Melo. (2020) Essential and nonessential metal effects on extracellular Leishmania amazonensis in vitro. Experimental Parasitology 209, pages 107826.
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Poonam Kumari, Mrigya Babuta, Alok Bhattacharya & Samudrala Gourinath. (2019) Structural and functional characterisation of phosphoserine phosphatase, that plays critical role in the oxidative stress response in the parasite Entamoeba histolytica. Journal of Structural Biology 206:2, pages 254-266.
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Farshid Yeganeh, Fereidoun Mahboudi, Nasser Gholijani, Farzaneh Barkhordari, Ghader Khalili & Eskandar Kamali-Sarvestani. (2019) Superoxide Dismutase B1, an Exacerbatory Antigen Elicits Interleukin-10 Production in Murine Leishmania major Infection. Archives of Clinical Infectious Diseases In Press:In Press.
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Somasri Dam, Pinaki Biswas & Raktim Ghosh. 2019. Oxidative Stress in Microbial Diseases. Oxidative Stress in Microbial Diseases 257 280 .
Ghulam Jeelani & Tomoyoshi Nozaki. 2019. Oxidative Stress in Microbial Diseases. Oxidative Stress in Microbial Diseases 209 227 .
Kristína Urbanová, Inmaculada Ramírez-Macías, Rubén Martín-Escolano, María Rosales, Olaf Cussó, Joan Serrano, Anna Company, Manuel Sánchez-Moreno, Miquel Costas, Xavi Ribas & Clotilde Marín. (2018) Effective Tetradentate Compound Complexes against Leishmania spp. that Act on Critical Enzymatic Pathways of These Parasites. Molecules 24:1, pages 134.
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Anshul Mishra, Mohd. Imran Khan, Pravin K. Jha, Ajay Kumar, Sushmita Das, Prolay Das, Pradeep Das & Kislay K. Sinha. (2018) Oxidative Stress-Mediated Overexpression of Uracil DNA Glycosylase in Leishmania donovani Confers Tolerance against Antileishmanial Drugs . Oxidative Medicine and Cellular Longevity 2018, pages 1-21.
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Liliana Soto-Castro, Laura Yuliana Plata-Guzmán, Elisa Elvira Figueroa-Angulo, Jaeson Santos Calla-Choque, Magda Reyes-López, Mireya de la Garza, Nidia León-Sicairos, José Antonio Garzón-Tiznado, Rossana Arroyo & Claudia León-Sicairos. (2017) Iron responsive-like elements in the parasite Entamoeba histolytica. Microbiology 163:9, pages 1329-1342.
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Angel H. Romero & Simón E. López. (2017) In silico molecular docking studies of new potential 4-phthalazinyl-hydrazones on selected Trypanosoma cruzi and Leishmania enzyme targets. Journal of Molecular Graphics and Modelling 76, pages 313-329.
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Alberto Guevara-Flores, José Martínez-González, Juan Rendón & Irene del Arenal. (2017) The Architecture of Thiol Antioxidant Systems among Invertebrate Parasites. Molecules 22:2, pages 259.
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E. C. Palmer‐Young, B. M. Sadd & L. S. Adler. (2016) Evolution of resistance to single and combined floral phytochemicals by a bumble bee parasite. Journal of Evolutionary Biology 30:2, pages 300-312.
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Narges Khabazzadeh Tehrani, Mehdi Mahdavi, Fatemeh Maleki, Somayeh Zarrati & Fatemeh Tabatabaie. (2014) The role of Montanide ISA 70 as an adjuvant in immune responses against Leishmania major induced by thiol-specific antioxidant-based protein vaccine. Journal of Parasitic Diseases 40:3, pages 760-767.
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Ghulam Jeelani & Tomoyoshi Nozaki. (2016) Entamoeba thiol-based redox metabolism: A potential target for drug development. Molecular and Biochemical Parasitology 206:1-2, pages 39-45.
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Pedro Morgado, Dipak Manna & Upinder Singh. (2016) Recent advances in Entamoeba biology: RNA interference, drug discovery, and gut microbiome. F1000Research 5, pages 2578.
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Raquel García-Hernández, Verónica Gómez-Pérez, Santiago Castanys & Francisco Gamarro. (2015) Fitness of Leishmania donovani Parasites Resistant to Drug Combinations. PLOS Neglected Tropical Diseases 9:4, pages e0003704.
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Vladimir F Niculescu. (2015) The stem cell biology of the protist pathogen entamoeba invadens in the context of eukaryotic stem cell evolution. Stem Cell Biology and Research 2:1, pages 2.
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Ghulam Jeelani, Dan Sato & Tomoyoshi Nozaki. 2015. Amebiasis. Amebiasis 331 349 .
Ghulam Jeelani, Dan Sato, Tomoyoshi Soga, Haruo Watanabe & Tomoyoshi Nozaki. (2014) Mass Spectrometric Analysis of l -Cysteine Metabolism: Physiological Role and Fate of l -Cysteine in the Enteric Protozoan Parasite Entamoeba histolytica . mBio 5:6.
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Khaja Faisal Tarique, Syed Arif Abdul Rehman & S. Gourinath. (2014) Structural elucidation of a dual-activity PAP phosphatase-1 from Entamoeba histolytica capable of hydrolysing both 3′-phosphoadenosine 5′-phosphate and inositol 1,4-bisphosphate . Acta Crystallographica Section D Biological Crystallography 70:7, pages 2019-2031.
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J.-M. KANG, H.-L. JU, W.-M. SOHN & B.-K. NA. (2013) Characterization of biochemical properties of a selenium-independent glutathione peroxidase of Cryptosporidium parvum . Parasitology 141:4, pages 570-578.
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F. Olmo, M. P. Clares, C. Marín, J. González, M. Inclán, C. Soriano, K. Urbanová, R. Tejero, M. J. Rosales, R. L. Krauth-Siegel, M. Sánchez-Moreno & E. García-España. (2014) Synthetic single and double aza-scorpiand macrocycles acting as inhibitors of the antioxidant enzymes iron superoxide dismutase and trypanothione reductase in Trypanosoma cruzi with promising results in a murine model. RSC Adv. 4:110, pages 65108-65120.
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Francisco Olmo, Clotilde Marín, M. Paz Clares, Salvador Blasco, M. Teresa Albelda, Conxa Soriano, Ramón Gutiérrez-Sánchez, Francisco Arrebola-Vargas, Enrique García-España & Manuel Sánchez-Moreno. (2013) Scorpiand-like azamacrocycles prevent the chronic establishment of Trypanosoma cruzi in a murine model. European Journal of Medicinal Chemistry 70, pages 189-198.
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Manuel Sánchez-Moreno, Fernando Gómez-Contreras, Pilar Navarro, Clotilde Marín, Francisco Olmo, María J. R. Yunta, Ana María Sanz, María José Rosales, Carmen Cano & Lucrecia Campayo. (2012) Phthalazine Derivatives Containing Imidazole Rings Behave as Fe-SOD Inhibitors and Show Remarkable Anti- T. cruzi Activity in Immunodeficient-Mouse Mode of Infection . Journal of Medicinal Chemistry 55:22, pages 9900-9913.
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Laura-Isobel McCall & Greg Matlashewski. (2012) Involvement of the Leishmania donovani virulence factor A2 in protection against heat and oxidative stress. Experimental Parasitology 132:2, pages 109-115.
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Guillermo Ortíz-Estrada, Sarahí Luna-Castro, Carolina Piña-Vázquez, Luisa Samaniego-Barrón, Nidia León-Sicairos, Jesús Serrano-Luna & Mireya de la Garza. (2012) Iron-saturated lactoferrin and pathogenic protozoa: could this protein be an iron source for their parasitic style of life?. Future Microbiology 7:1, pages 149-164.
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Afzal Husain, Ghulam Jeelani, Dan Sato & Tomoyoshi Nozaki. (2011) Global analysis of gene expression in response to L-Cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica. BMC Genomics 12:1.
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