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Review Article

Understanding the biology of 16 kDa antigen of Mycobacterium tuberculosis: Scope in diagnosis, vaccine design and therapy

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Pages 349-357 | Received 12 Apr 2011, Accepted 15 Jul 2011, Published online: 15 Sep 2011

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Read on this site (2)

Babban Jee, Sanjay Kumar, Renu Yadav, Yogesh Singh, Anuj Kumar & Naveen Sharma. (2018) Ursolic acid and carvacrol may be potential inhibitors of dormancy protein small heat shock protein16.3 of Mycobacterium tuberculosis. Journal of Biomolecular Structure and Dynamics 36:13, pages 3434-3443.
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Hongmei Kong, Chunsheng Dong & Sidong Xiong. (2014) A novel vaccine p846 encoding Rv3615c, Mtb10.4, and Rv2660c elicits robust immune response and alleviates lung injury induced by Mycobacterium infection. Human Vaccines & Immunotherapeutics 10:2, pages 378-390.
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Articles from other publishers (14)

Min Han Lew, Mohd Nor Norazmi, Fazlina Nordin & Gee Jun Tye. (2022) A novel peptide vaccination augments cytotoxic CD8+ T-cell responses against Mycobacterium tuberculosis HspX antigen. Immunobiology 227:3, pages 152201.
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Sadhana Sundararajan & Rajiniraja Muniyan. (2021) Latent tuberculosis: interaction of virulence factors in Mycobacterium tuberculosis. Molecular Biology Reports 48:8, pages 6181-6196.
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Sylvia Annabel Dass, Mohd Nor Norazmi, Armando Acosta, Maria E. Sarmiento & Gee Jun Tye. (2020) TCR-like domain antibody against Mycobacterium tuberculosis (Mtb) heat shock protein antigen presented by HLA-A*11 and HLA-A*24. International Journal of Biological Macromolecules 155, pages 305-314.
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Min Han Lew, Mohd Nor Norazmi & Gee Jun Tye. (2020) Enhancement of immune response against Mycobacterium tuberculosis HspX antigen by incorporation of combined molecular adjuvant (CASAC). Molecular Immunology 117, pages 54-64.
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Nida Mubin, Susanta Pahari, Mohammad Owais & Swaleha Zubair. (2018) Mycobacterium tuberculosis host cell interaction: Role of latency associated protein Acr-1 in differential modulation of macrophages. PLOS ONE 13:11, pages e0206459.
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Sylvia Annabel Dass, Mohd Nor Norazmi, Armando Acosta Dominguez, Maria Elena Sarmiento Garcia San Miguel & Gee Jun Tye. (2018) Generation of a T cell receptor (TCR)-like single domain antibody (sDAb) against a Mycobacterium Tuberculosis (Mtb) heat shock protein (HSP) 16kDa antigen presented by Human Leukocyte Antigen (HLA)-A*02. Molecular Immunology 101, pages 189-196.
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Mohammed Amir, Mohammad Aqdas, Sajid Nadeem, Kaneez F. Siddiqui, Nargis Khan, Javaid A. Sheikh & Javed N. Agrewala. (2017) Diametric Role of the Latency-Associated Protein Acr1 of Mycobacterium tuberculosis in Modulating the Functionality of Pre- and Post-maturational Stages of Dendritic Cells. Frontiers in Immunology 8.
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Santhi Devasundaram, Akilandeswari Gopalan, Sulochana D. Das & Alamelu Raja. (2016) Proteomics Analysis of Three Different Strains of Mycobacterium tuberculosis under In vitro Hypoxia and Evaluation of Hypoxia Associated Antigen’s Specific Memory T Cells in Healthy Household Contacts. Frontiers in Microbiology 7.
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Tao Chen, Jinfei Lin, Wei Wang, Joy Fleming, Liang Chen, Yunxia Wang, Haicheng Li, Huixin Guo, Jie Zhou, Xunxun Chen, Yuhui Chen, Qinghua Liao, Yang Shu, Yaoju Tan, Meiling Yu, Guozhou Li, Lin Zhou, Qiu Zhong, Lijun Bi, Lina Guo & Meigui Zhao. (2015) Cytokine and Antibody Based Diagnostic Algorithms for Sputum Culture-Positive Pulmonary Tuberculosis. PLOS ONE 10:12, pages e0144705.
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K F Siddiqui, M Amir, N Khan, G Rama Krishna, J A Sheikh, K Rajagopal & J N Agrewala. (2015) Prime-boost vaccination strategy with bacillus Calmette–Guérin (BCG) and liposomized alpha-crystalline protein 1 reinvigorates BCG potency. Clinical and Experimental Immunology 181:2, pages 286-296.
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Monalisa Martins Trentini, Fábio Muniz de Oliveira, Marilisa Pedroso Nogueira Gaeti, Aline Carvalho Batista, Eliana Martins Lima, André Kipnis & Ana Paula Junqueira-Kipnis. (2014) Microstructured liposome subunit vaccines reduce lung inflammation and bacterial load after Mycobacterium tuberculosis infection. Vaccine 32:34, pages 4324-4332.
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Kaneez F. Siddiqui, Mohammed Amir, Rama Krishna Gurram, Nargis Khan, Ashish Arora, Kammara Rajagopal & Javed N. Agrewala. (2014) Latency-Associated Protein Acr1 Impairs Dendritic Cell Maturation and Functionality: A Possible Mechanism of Immune Evasion by Mycobacterium tuberculosis. The Journal of Infectious Diseases 209:9, pages 1436-1445.
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Ana Paula Junqueira-Kipnis, Fábio Muniz de Oliveira, Monalisa Martins Trentini, Sangeeta Tiwari, Bing Chen, Danilo Pires Resende, Bruna D. S. Silva, Mei Chen, Lydia Tesfa, William R. Jacobs & André Kipnis. (2013) Prime–Boost with Mycobacterium smegmatis Recombinant Vaccine Improves Protection in Mice Infected with Mycobacterium tuberculosis. PLoS ONE 8:11, pages e78639.
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Laura Marongiu, Marta Donini, Lara Toffali, Elena Zenaro & Stefano Dusi. (2013) ESAT-6 and HspX Improve the Effectiveness of BCG to Induce Human Dendritic Cells-Dependent Th1 and NK Cells Activation. PLoS ONE 8:10, pages e75684.
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