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Research Article

On the Role of DNA Double-Strand Breaks in Toxicity and Carcinogenesis

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Pages 155-174 | Published online: 25 Sep 2008

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Annie Tremblay, Maria Jasin & Pierre Chartrand. (2000) A Double-Strand Break in a Chromosomal LINE Element Can Be Repaired by Gene Conversion with Various Endogenous LINE Elements in Mouse Cells. Molecular and Cellular Biology 20:1, pages 54-60.
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Ping XiongRong ZhengLi-E WangMelissa L. BondyHongbing ShenMary M. BorerQingyi WeiErich M. Sturgis. (2005) A Pilot Case-Control Study of Gamma-Radiation Sensitivity and Risk of Papillary Thyroid Cancer. Thyroid 15:2, pages 94-99.
Crossref
Takehiko Nohmi & Ken-ichi Masumura. (2005) Molecular nature of intrachromosomal deletions and base substitutions induced by environmental mutagens. Environmental and Molecular Mutagenesis 45:2-3, pages 150-161.
Crossref
Chi-Hao Wu & Gow-Chin Yen. (2004) Antigenotoxic properties of Cassia tea (Cassia tora L.): Mechanism of action and the influence of roasting process. Life Sciences 76:1, pages 85-101.
Crossref
Ramesh Raghupathi. (2006) Cell Death Mechanisms Following Traumatic Brain Injury. Brain Pathology 14:2, pages 215-222.
Crossref
Rong Zheng, Li‐E Wang, Melissa L. Bondy, Qingyi Wei & Erich M. Sturgis. (2004) Gamma radiation sensitivity and risk of malignant and benign salivary gland tumors. Cancer 100:3, pages 561-567.
Crossref
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Crossref
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Crossref
A. Lazo, J. Tassello, V. Jayarama, A. Ohagen, V. Gibaja, E. Kramer, A. Marmorato, D. Billia-Shaveet, A. Purmal, F. Brown & J. Chapman. (2002) Broad-spectrum virus reduction in red cell concentrates using INACTINE™ PEN110 chemistry. Vox Sanguinis 83:4, pages 313-323.
Crossref
Ayfer Akköse, Beyhan Ömer, Günnur Deniz & Emin Darendeliler. (2006) Detection of DNA single‐strand breaks and glutathione in mononuclear blood cells of radiotherapy technicians. Addiction Biology 7:4, pages 409-414.
Crossref
Loren D. Fast, Gilbert DiLeone, Clark M. Edson & Andrei Purmal. (2002) PEN110 treatment functionally inactivates the PBMNCs present in RBC units: comparison to the effects of exposure to gamma irradiation. Transfusion 42:10, pages 1318-1325.
Crossref
Mathilde Fréchet, Yvan Canitrot, Anne Bieth, Eugenia Dogliotti, Christophe Cazaux & Jean-Sébastien Hoffmann. (2002) Deregulated DNA polymerase β strengthens ionizing radiation-induced nucleotidic and chromosomal instabilities. Oncogene 21:15, pages 2320-2327.
Crossref
Young Chul Kim, Jeong Tae Koh, Boo Ahn Shin, Kyu Youn Ahn, Bong Kyu Choi, Chang Guhn Kim & Kyung Keun Kim. (2002) An Antisense Construct of Full-Length Human RAD50 cDNA Confers Sensitivity to Ionizing Radiation and Alkylating Agents on Human Cell Lines . Radiation Research 157:1, pages 19-25.
Crossref
G.N Ray, M Shahid & S.A Husain. (2001) Status of chromosome breaks and gaps in breast cancer. Cancer Genetics and Cytogenetics 130:2, pages 155-159.
Crossref
Yunfu Lin & Alan S Waldman. (2001) Capture of DNA Sequences at Double-Strand Breaks in Mammalian Chromosomes. Genetics 158:4, pages 1665-1674.
Crossref
P J E Quintana, Efrem A H Neuwirth & Andrew J Grosovsky. (2001) Interchromosomal Gene Conversion at an Endogenous Human Cell Locus. Genetics 158:2, pages 757-767.
Crossref
Chi-Hao Wu, Chiu-Lan Hsieh, Tuzz-Ying Song & Gow-Chin Yen. (2001) Inhibitory Effects of Cassia tora L. on Benzo[ a ]pyrene-Mediated DNA Damage toward HepG2 Cells . Journal of Agricultural and Food Chemistry 49:5, pages 2579-2586.
Crossref
Rupesh P. Amin & Gisela Witz. (2022) DNA-Protein Crosslink and DNA Strand Break Formation in HL-60 Cells Treated with Trans,trans -Muconaldehyde, Hydroquinone and Their Mixtures . International Journal of Toxicology 20:2, pages 69-80.
Crossref
Kum Kum Khanna & Stephen P. Jackson. (2001) DNA double-strand breaks: signaling, repair and the cancer connection. Nature Genetics 27:3, pages 247-254.
Crossref
Ram Parshad & Katherine K. Sanford. (2001) Radiation-induced chromatid breaks and deficient DNA repair in cancer predisposition. Critical Reviews in Oncology/Hematology 37:2, pages 87-96.
Crossref
Fermín A. Goytisolo, Enrique Samper, Juan Martín-Caballero, Paul Finnon, Eloísa Herrera, Juana M. Flores, Simon D. Bouffler & María A. Blasco. (2000) Short Telomeres Result in Organismal Hypersensitivity to Ionizing Radiation in Mammals. The Journal of Experimental Medicine 192:11, pages 1625-1636.
Crossref
RAMESH RAGHUPATHI, DAVID I. GRAHAM & TRACY K. McINTOSH. (2000) Apoptosis After Traumatic Brain Injury. Journal of Neurotrauma 17:10, pages 927-938.
Crossref
Min Chen & Anna von Mikecz. (2000) Specific Inhibition of rRNA Transcription and Dynamic Relocation of Fibrillarin Induced by Mercury. Experimental Cell Research 259:1, pages 225-238.
Crossref
Ayda Trisnawaty Yusuf, Laurence Vian, Robert Sabatier & Jean-Paul Cano. (2000) In vitro detection of indirect-acting genotoxins in the comet assay using Hep G2 cells. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 468:2, pages 227-234.
Crossref
Ethel Moustacchi. (2000) DNA damage and repair: consequences on dose-responses. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 464:1, pages 35-40.
Crossref
Susan E Ingraham, Roy A Lynch, Sekar Kathiresan, Alan J Buckler & Anil G Menon. (1999) hREC2, a RAD51-like Gene, is Disrupted by t(12;14)(q15;q24.1) in a Uterine Leiomyoma. Cancer Genetics and Cytogenetics 115:1, pages 56-61.
Crossref
Steven J Robles, Paul W Buehler, Adam Negrusz & Guy R Adami. (1999) Permanent cell cycle arrest in asynchronously proliferating normal human fibroblasts treated with doxorubicin or etoposide but not camptothecin. Biochemical Pharmacology 58:4, pages 675-685.
Crossref
Abdellah Mansouri, Isabelle Gaou, Caroline de Kerguenec, Sabine Amsellem, Delphine Haouzi, Alain Berson, Alain Moreau, Gérard Feldmann, Philippe Lettéron, Dominique Pessayre & Bernard Fromenty. (1999) An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice. Gastroenterology 117:1, pages 181-190.
Crossref
Kevin D Mills, David A Sinclair & Leonard Guarente. (1999) MEC1-Dependent Redistribution of the Sir3 Silencing Protein from Telomeres to DNA Double-Strand Breaks. Cell 97:5, pages 609-620.
Crossref
E.H Vock, W.K Lutz, O Ilinskaya & S Vamvakas. (1999) Discrimination between genotoxicity and cytotoxicity for the induction of DNA double-strand breaks in cells treated with aldehydes and diepoxides. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 441:1, pages 85-93.
Crossref
Kunlin Jin, Jun Chen, Tetsuya Nagayama, Minzhi Chen, Jennifer Sinclair, Steven H. Graham & Roger P. Simon. (2008) In Situ Detection of Neuronal DNA Strand Breaks Using the Klenow Fragment of DNA Polymerase I Reveals Different Mechanisims of Neuron Death After Global Cerebral Ischemia. Journal of Neurochemistry 72:3, pages 1204-1214.
Crossref
E.H Vock, W.K Lutz, P Hormes, H.D Hoffmann & S Vamvakasa. (1998) Discrimination between genotoxicity and cytotoxicity in the induction of DNA double-strand breaks in cells treated with etoposide, melphalan, cisplatin, potassium cyanide, Triton X-100, and γ-irradiation. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 413:1, pages 83-94.
Crossref

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