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Review Article

DNA methyltransferases: Mechanistic models derived from kinetic analysis

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Pages 97-193 | Received 27 Jun 2011, Accepted 02 Sep 2011, Published online: 20 Jan 2012

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Lanxuan Liu, Ting Shi, Kendall N. Houk & Yi-Lei Zhao. (2019) Understanding the R882H mutation effects of DNA methyltransferase DNMT3A: a combination of molecular dynamics simulations and QM/MM calculations. RSC Advances 9:54, pages 31425-31434.
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Mathieu Fossépré, Marie E. Trévisan, Valentine Cyriaque, Ruddy Wattiez, David Beljonne, Sébastien Richeter, Sébastien Clément & Mathieu Surin. (2019) Detection of the Enzymatic Cleavage of DNA through Supramolecular Chiral Induction to a Cationic Polythiophene. ACS Applied Bio Materials 2:5, pages 2125-2136.
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Ewa Wons, Iwona Mruk & Tadeusz Kaczorowski. (2018) Isospecific adenine DNA methyltransferases show distinct preferences towards DNA substrates. Scientific Reports 8:1.
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Gaurav Gulati & Hermine I. Brunner. (2018) Environmental triggers in systemic lupus erythematosus. Seminars in Arthritis and Rheumatism 47:5, pages 710-717.
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Yan Wang, ZhongSheng Sun & Moshe Szyf. (2017) S-adenosyl-methionine (SAM) alters the transcriptome and methylome and specifically blocks growth and invasiveness of liver cancer cells. Oncotarget 8:67, pages 111866-111881.
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Ning Ma & Arjan van der Vaart. (2017) Free Energy Coupling between DNA Bending and Base Flipping. Journal of Chemical Information and Modeling 57:8, pages 2020-2026.
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S.V. Tarlachkov, O.V. Dyachenko, A.M. Cherevatenko, N.V. Rudenko & T.V. Shevchuk. (2014) Cloning, purification and characterization of translationally fused protein DNA methyltransferase M•HhaI-EGFP. Process Biochemistry 49:12, pages 2170-2173.
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Feng-Lai Yuan, Xia Li, Rui-Sheng Xu, Dong-Lin Jiang & Xiao-Gang Zhou. (2014) DNA Methylation: Roles in Rheumatoid Arthritis. Cell Biochemistry and Biophysics 70:1, pages 77-82.
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C-G Miao, J-T Yang, Y-Y Yang, C-L Du, C Huang, Y Huang, L Zhang, X-W Lv, Y Jin & J Li. (2014) Critical role of DNA methylation in the pathogenesis of systemic lupus erythematosus: new advances and future challenges. Lupus 23:8, pages 730-742.
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Rachel M. Smith, Christian Pernstich & Stephen E. Halford. (2014) TstI, a Type II restriction–modification protein with DNA recognition, cleavage and methylation functions in a single polypeptide. Nucleic Acids Research 42:9, pages 5809-5822.
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Annika Butterer, Christian Pernstich, Rachel M. Smith, Frank Sobott, Mark D. Szczelkun & J?lia T?th. (2014) Type III restriction endonucleases are heterotrimeric: comprising one helicase?nuclease subunit and a dimeric methyltransferase that binds only one specific DNA. Nucleic Acids Research 42:8, pages 5139-5150.
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Cheng-gui Miao, Ying-ying Yang, Xu He & Jun Li. (2013) New advances of DNA methylation and histone modifications in rheumatoid arthritis, with special emphasis on MeCP2. Cellular Signalling 25:4, pages 875-882.
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O. M. Doyle, K. Tsaneva-Atansaova, J. Harte, P. A. Tiffin, P. Tino & Vanessa Diaz-Zuccarini. (2013) Bridging Paradigms: Hybrid Mechanistic-Discriminative Predictive Models. IEEE Transactions on Biomedical Engineering 60:3, pages 735-742.
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Rachel M. Smith, Alistair J. Jacklin, Jacqueline J. T. Marshall, Frank Sobott & Stephen E. Halford. (2013) Organization of the BcgI restriction–modification protein for the transfer of one methyl group to DNA. Nucleic Acids Research 41:1, pages 405-417.
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Marién Pascual & Sergio RoaMarién Pascual & Sergio Roa. 2013. Epigenetic Approaches to Allergy Research. Epigenetic Approaches to Allergy Research 23 50 .

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