Citations (127)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (9)
Josephine Kugler, Bettina Huhse, Tewes Tralau & Andreas Luch. (2017) Embryonic stem cells and the next generation of developmental toxicity testing. Expert Opinion on Drug Metabolism & Toxicology 13:8, pages 833-841.
Read now
Read now
H.-Y. Ho, M.-L. Cheng & D. T.-Y. Chiu. (2014) Glucose-6-phosphate dehydrogenase – beyond the realm of red cell biology. Free Radical Research 48:9, pages 1028-1048.
Read now
Read now
Md.
Saydur Rahman, Izhar
A. Khan & Peter Thomas. (2011) Tryptophan Hydroxylase: A Target for Neuroendocrine Disruption. Journal of Toxicology and Environmental Health, Part B 14:5-7, pages 473-494.
Read now
Read now
Hung-yao Ho, Mei-ling Cheng & Daniel Tsun-yee Chiu. (2007) Glucose-6-phosphate dehydrogenase – from oxidative stress to cellular functions and degenerative diseases. Redox Report 12:3, pages 109-118.
Read now
Read now
M. R. Loeken. (2004) Free radicals and birth defects. The Journal of Maternal-Fetal & Neonatal Medicine 15:1, pages 6-14.
Read now
Read now
Torbjörn Tomson. (2001) Teratogenesis with antiepileptic drugs: practical management of young women with epilepsy. Expert Review of Neurotherapeutics 1:2, pages 192-198.
Read now
Read now
Kimberly P. Miller & Kenneth S. Ramos. (2001) IMPACT OF CELLULAR METABOLISM ON THE BIOLOGICAL EFFECTS OF BENZO[A]PYRENE AND RELATED HYDROCARBONS†. Drug Metabolism Reviews 33:1, pages 1-35.
Read now
Read now
Mont R. Juchau, Hélène Boutelet-Bochan & Ying Huang. (1998) Cytochrome-P450-Dependent Biotransformation of Xenobiotics in Human and Rodent Embryonic Tissues. Drug Metabolism Reviews 30:3, pages 541-568.
Read now
Read now
Jukka Hakkola, Olavi Pelkonen, Markku Pasanen & Hannu Raunio. (1998) Xenobiotic-Metabolizing Cytochrome P450 Enzymes in the Human Feto-Placental Unit: Role in Intrauterine Toxicity. Critical Reviews in Toxicology 28:1, pages 35-72.
Read now
Read now
Articles from other publishers (118)
Joseph V. Madrid, Madeline K. M. Vera-Colón & Nicole I. zur Nieden. (2023) Perturbations in Osteogenic Cell Fate Following Exposure to Constituents Present in Tobacco: A Combinatorial Study. Toxics 11:12, pages 998.
Crossref
Crossref
Laken Kruger, Samantha Lapehn, Alison Paquette, Dilip Kumar Singh, James MacDonald, Theo K. Bammler, Daniel A. Enquobahrie, Qi Zhao, Khyobeni Mozhui, Sheela Sathyanarayana & Bhagwat Prasad. (2023) Characterization of Xenobiotic and Steroid Disposition Potential of Human Placental Tissue and Cell Lines (BeWo, JEG-3, JAR, and HTR-8/SVneo) by Quantitative Proteomics. Drug Metabolism and Disposition 51:8, pages 1053-1063.
Crossref
Crossref
Albert E. Chudley. 2023. Development of the Cerebellum from Molecular Aspects to Diseases. Development of the Cerebellum from Molecular Aspects to Diseases
363
388
.
Huajun Feng, Liyang Xu, Ruya Chen, Xiangjuan Ma, Hua Qiao, Nannan Zhao, Yangcheng Ding & Di Wu. (2022) Detoxification mechanisms of electroactive microorganisms under toxicity stress: A review. Frontiers in Microbiology 13.
Crossref
Crossref
Yusuke Marikawa. (2022) Toward better assessments of developmental toxicity using stem cell‐based in vitro embryogenesis models. Birth Defects Research 114:16, pages 972-982.
Crossref
Crossref
Jennifer J Adibi, Alexander J Layden, Rahel L Birru, Alexandra Miragaia, Xiaoshuang Xun, Megan C Smith, Qing Yin, Marisa E Millenson, Thomas G O’Connor, Emily S Barrett, Nathaniel W Snyder, Shyamal Peddada & Rod T Mitchell. (2021) First trimester mechanisms of gestational sac placental and foetal teratogenicity: a framework for birth cohort studies. Human Reproduction Update 27:4, pages 747-770.
Crossref
Crossref
Donald J. AbrahamDeepak K. Dalvie & Bernard Testa. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery
1
139
.
María José Marín Castro & Andrés Eduardo Marín Castro. (2020) Microcefalia antes de la llegada del virus Zika: una revisión de tema. Medicina UPB 39:1, pages 42-48.
Crossref
Crossref
Jada Bittle, Edenia C Menezes, Michael L McCormick, Douglas R Spitz, Michael Dailey & Hanna E Stevens. (2019) The Role of Redox Dysregulation in the Effects of Prenatal Stress on Embryonic Interneuron Migration. Cerebral Cortex 29:12, pages 5116-5130.
Crossref
Crossref
Haixing Li & Jed N. Lampe. (2019) Neonatal cytochrome P450 CYP3A7: A comprehensive review of its role in development, disease, and xenobiotic metabolism. Archives of Biochemistry and Biophysics 673, pages 108078.
Crossref
Crossref
Dong‑Ho Bak, Jungtae Na, Mi Choi, Byung Lee, Chang Oh, Jeom‑Yong Kim, Hae Han, Moo Kim, Tae Kim & Beom Kim. (2018) Anti‑apoptotic effects of human placental hydrolysate against hepatocyte toxicity in�vivo and in�vitro. International Journal of Molecular Medicine.
Crossref
Crossref
P.G. Wells & L.M. Winn. 2018. Comprehensive Toxicology. Comprehensive Toxicology
63
85
.
Peter G. Alexander, Ricardo Londono, Thomas P. Lozito & Rocky S. Tuan. 2018. The Genetics and Development of Scoliosis. The Genetics and Development of Scoliosis
31
61
.
Милютина, Yuliya Milyutina, Пустыгина, Antonina Pustygina, Щербицкая, Anastasiya Shcherbitskaya, Залозняя, Irina Zaloznyaya, Арутюнян & Aleksandr Arutyunyan. (2017) THE COMPARISON OF OXIDATIVE STRESS PROFILES IN RAT BLOOD SERUM IN DIFFERENT EXPERIMENTAL MODELS OF HYPERHOMOCYSTEINEMIA. Бюллетень Восточно-Сибирского научного центра Сибирского отделения Российской академии медицинских наук 1:3, pages 120-123.
Crossref
Crossref
Erica L. L. Warkus & Yusuke Marikawa. (2017) Exposure-Based Validation of an In Vitro Gastrulation Model for Developmental Toxicity Assays. Toxicological Sciences 157:1, pages 235-245.
Crossref
Crossref
Albert E. Chudley. 2017. Development of the Cerebellum from Molecular Aspects to Diseases. Development of the Cerebellum from Molecular Aspects to Diseases
275
300
.
Ean-Jeong Seo & Thomas Efferth. 2017. Toxicology of Herbal Products. Toxicology of Herbal Products
217
235
.
Larissa M. Williams, Briony A. Lago, Andrew G. McArthur, Amogelang R. Raphenya, Nicholas Pray, Nabil Saleem, Sophia Salas, Katherine Paulson, Roshni S. Mangar, Yang Liu, Andy H. Vo & Jordan A. Shavit. (2016) The transcription factor, Nuclear factor, erythroid 2 (Nfe2), is a regulator of the oxidative stress response during Danio rerio development. Aquatic Toxicology 180, pages 141-154.
Crossref
Crossref
Mark E. Hahn, Alicia R. Timme-Laragy, Sibel I. Karchner & John J. Stegeman. (2015) Nrf2 and Nrf2-related proteins in development and developmental toxicity: Insights from studies in zebrafish (Danio rerio). Free Radical Biology and Medicine 88, pages 275-289.
Crossref
Crossref
Sabine Schnell, Kafilat Bawa-Allah, Adebayo Otitoloju, Christer Hogstrand, Thomas H. Miller, Leon P. Barron & Nic R. Bury. (2015) Environmental monitoring of urban streams using a primary fish gill cell culture system (FIGCS). Ecotoxicology and Environmental Safety 120, pages 279-285.
Crossref
Crossref
Hanna Kim, Brittany M. Miller, Dokyong Kim, Betty J. Herring, Amanda L. Logsdon, Jarrett E. Lockard, Xuan T. Lam, Kyle K. Wells, Ronald D. Hood & Melissa M. Bailey. (2015) Investigations into Concurrent Exposure to Green Tea Extract and Phenytoin on the Incidence of Cleft Palate in CD-1 Mice. Transactions of the Kansas Academy of Science 118:1 & 2, pages 97-104.
Crossref
Crossref
Mark E. Hahn, Andrew G. McArthur, Sibel I. Karchner, Diana G. Franks, Matthew J. Jenny, Alicia R. Timme-Laragy, John J. Stegeman, Bruce R. Woodin, Michael J. Cipriano & Elwood Linney. (2014) The Transcriptional Response to Oxidative Stress during Vertebrate Development: Effects of tert-Butylhydroquinone and 2,3,7,8-Tetrachlorodibenzo-p-Dioxin. PLoS ONE 9:11, pages e113158.
Crossref
Crossref
Marleen M.H.J. van Gelder, Iris A.L.M. van Rooij, Lolkje T.W. de Jong-van den Berg & Nel Roeleveld. (2014) Teratogenic Mechanisms Associated with Prenatal Medication Exposure. Therapies 69:1, pages 13-24.
Crossref
Crossref
Christoph Ufer, Hartmut Kuehn, Tang Ling Yin & Chi Chiu Wang. 2014. Systems Biology of Free Radicals and Antioxidants. Systems Biology of Free Radicals and Antioxidants
537
565
.
Annmarie Ramkissoon, Aaron M. Shapiro, Margaret M. Loniewska & Peter G. Wells. 2013. Molecular Basis of Oxidative Stress. Molecular Basis of Oxidative Stress
237
310
.
Jianling Sun, Qiu Zhang, Zhiping Wang & Bing Yan. (2013) Effects of Nanotoxicity on Female Reproductivity and Fetal Development in Animal Models. International Journal of Molecular Sciences 14:5, pages 9319-9337.
Crossref
Crossref
Krystyna Sitarek, Jolanta Gromadzińska, Piotr Lutz, Jan Stetkiewicz, Radosław Świercz & Wojciech Wąsowicz. (2012) Fertility and developmental toxicity studies of diethylene glycol monobutyl ether (DGBE) in rats. International Journal of Occupational Medicine and Environmental Health 25:4.
Crossref
Crossref
Patricia S. Brocardo, Joana Gil-Mohapel & Brian R. Christie. (2011) The role of oxidative stress in fetal alcohol spectrum disorders. Brain Research Reviews 67:1-2, pages 209-225.
Crossref
Crossref
Takumi Ito, Hideki Ando & Hiroshi Handa. (2011) Teratogenic effects of thalidomide: molecular mechanisms. Cellular and Molecular Life Sciences 68:9, pages 1569-1579.
Crossref
Crossref
Winnie Jeng, Annmarie Ramkissoon & Peter G. Wells. (2011) Reduced DNA oxidation in aged prostaglandin H synthase-1 knockout mice. Free Radical Biology and Medicine 50:4, pages 550-556.
Crossref
Crossref
Torbjörn Tomson & Dina Battino. 2011. Pediatric Clinical Pharmacology. Pediatric Clinical Pharmacology
295
315
.
Christoph UferChi Chiu WangAstrid BorchertDagmar HeydeckHartmut Kuhn. (2010) Redox Control in Mammalian Embryo Development. Antioxidants & Redox Signaling 13:6, pages 833-875.
Crossref
Crossref
Robert G. Ellis-Hutchings & Edward W. Carney. (2010) Whole embryo culture: a “New” technique that enabled decades of mechanistic discoveries. Birth Defects Research Part B: Developmental and Reproductive Toxicology 89:4, pages 304-312.
Crossref
Crossref
M. M. H. J. van Gelder, I. A. L. M. van Rooij, R. K. Miller, G. A. Zielhuis, L. T. W. de Jong-van den Berg & N. Roeleveld. (2010) Teratogenic mechanisms of medical drugs. Human Reproduction Update 16:4, pages 378-394.
Crossref
Crossref
Sema T. Koz, Nevhayat T. Gouwy, Nevgul Demir, Viktor S. Nedzvetsky, Ebru Etem & Giyasettin Baydas. (2010) Effects of maternal hyperhomocysteinemia induced by methionine intake on oxidative stress and apoptosis in pup rat brain. International Journal of Developmental Neuroscience 28:4, pages 325-329.
Crossref
Crossref
Peter G. Alexander & Rocky S. Tuan. (2010) Role of environmental factors in axial skeletal dysmorphogenesis. Birth Defects Research Part C: Embryo Today: Reviews 90:2, pages 118-132.
Crossref
Crossref
Donald J. AbrahamBernard Testa. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery
403
454
.
Michal Dubovický. (2010) Neurobehavioral manifestations of developmental impairment of the brain. Interdisciplinary Toxicology 3:2.
Crossref
Crossref
P.G. Wells & L.M. Winn. 2010. Comprehensive Toxicology. Comprehensive Toxicology
95
115
.
W. Y. Chan, T. B. Ng, Joyce S. Y. Lam, Jack H. Wong, K. T. Chu, P. H. K. Ngai, S. K. Lam & H. X. Wang. (2009) The mushroom ribosome-inactivating protein lyophyllin exerts deleterious effects on mouse embryonic development in vitro. Applied Microbiology and Biotechnology 85:4, pages 985-993.
Crossref
Crossref
Peter G. Wells, Crystal J. J. Lee, Gordon P. McCallum, Julia Perstin & Patricia A. Harper. 2010. Adverse Drug Reactions. Adverse Drug Reactions
131
162
.
Peter G. Alexander & Rocky S. Tuan. 2010. The Genetics and Development of Scoliosis. The Genetics and Development of Scoliosis
47
72
.
Bernard Testa & Stefanie D. Krämer. (2009) The Biochemistry of Drug Metabolism – An Introduction. Chemistry & Biodiversity 6:5, pages 591-684.
Crossref
Crossref
Mojmír Mach, Michal Dubovický, Jana Navarová, Ingrid Brucknerová & Eduard Ujházy. (2009) Experimental modeling of hypoxia in pregnancy and early postnatal life. Interdisciplinary Toxicology 2:1, pages 28-32.
Crossref
Crossref
Peter G. Wells, Gordon P. McCallum, Connie S. Chen, Jeffrey T. Henderson, Crystal J. J. Lee, Julia Perstin, Thomas J. Preston, Michael J. Wiley & Andrea W. Wong. (2009) Oxidative Stress in Developmental Origins of Disease: Teratogenesis, Neurodevelopmental Deficits, and Cancer. Toxicological Sciences 108:1, pages 4-18.
Crossref
Crossref
Andrea W. Wong, Gordon P. McCallum, Winnie Jeng & Peter G. Wells. (2008) Oxoguanine Glycosylase 1 Protects Against Methamphetamine-Enhanced Fetal Brain Oxidative DNA Damage and Neurodevelopmental Deficits. The Journal of Neuroscience 28:36, pages 9047-9054.
Crossref
Crossref
Hayat Z. Elbashir, AbdelMoniem .I. Mustafa, Abdullahi H. El-Tinay & Elfadil E. Babiker. (2008) Biochemical Characteristics of Sorghum (Sorghum bicolor L. Moench) Flour Supplemented with Cluster Bean (Cyamopsis tetragonolaba L.): Influence of Fermentation and/or Cooking. Journal of Biological Sciences 8:4, pages 722-729.
Crossref
Crossref
Giyasettin Baydas, Sema T. Koz, Mehmet Tuzcu, Ebru Etem & Viktor S. Nedzvetsky. (2007) Melatonin inhibits oxidative stress and apoptosis in fetal brains of hyperhomocysteinemic rat dams. Journal of Pineal Research 43:3, pages 225-231.
Crossref
Crossref
Asher Ornoy. (2007) Embryonic oxidative stress as a mechanism of teratogenesis with special emphasis on diabetic embryopathy. Reproductive Toxicology 24:1, pages 31-41.
Crossref
Crossref
Sophie Petropoulos, Grazyna M. Kalabis, William Gibb & Stephen G. Matthews. (2007) Functional Changes of Mouse Placental Multidrug Resistance Phosphoglycoprotein (ABCB1) With Advancing Gestation and Regulation by Progesterone. Reproductive Sciences 14:4, pages 321-328.
Crossref
Crossref
Elena Menegola, Francesca Di Renzo, Maria Luisa Broccia & Erminio Giavini. (2006) Inhibition of histone deacetylase as a new mechanism of teratogenesis. Birth Defects Research Part C: Embryo Today: Reviews 78:4, pages 345-353.
Crossref
Crossref
Joanne Wan & Louise M. Winn. (2006) In utero–initiated cancer: The role of reactive oxygen species. Birth Defects Research Part C: Embryo Today: Reviews 78:4, pages 326-332.
Crossref
Crossref
Yadvinder Bhuller, Winnie Jeng & Peter G. Wells. (2006) Variable In Vivo Embryoprotective Role for Ataxia-Telangiectasia–Mutated against Constitutive and Phenytoin-Enhanced Oxidative Stress in Atm Knockout Mice. Toxicological Sciences 93:1, pages 146-155.
Crossref
Crossref
Faezeh Fatemi, Abdolamir Allameh, Abolfazl Dadkhah, Mehdi Forouzandeh, Somayeh Kazemnejad & Roya Sharifi. (2006) Changes in hepatic cytosolic glutathione S-transferase activity and expression of its class-P during prenatal and postnatal period in rats treated with aflatoxin B1. Archives of Toxicology 80:9, pages 572-579.
Crossref
Crossref
Connie S. Chen & Peter G. Wells. (2006) Enhanced tumorigenesis in p53 knockout mice exposed in utero to high-dose vitamin E. Carcinogenesis 27:7, pages 1358-1368.
Crossref
Crossref
Ericka N. Defoort, Perry M. Kim & Louise M. Winn. (2006) Valproic Acid Increases Conservative Homologous Recombination Frequency and Reactive Oxygen Species Formation: A Potential Mechanism for Valproic Acid-Induced Neural Tube Defects. Molecular Pharmacology 69:4, pages 1304-1310.
Crossref
Crossref
Winnie Jeng, Annmarie Ramkissoon, Toufan Parman & Peter G. Wells. (2006)
Prostaglandin H synthase‐catalyzed bioactivation of amphetamines to free radical intermediates that cause CNS regional DNA oxidation and nerve terminal degeneration
1
. The FASEB Journal 20:6, pages 638-650.
Crossref
Crossref
Mary R. Loeken. (2016) Advances in Understanding the Molecular Causes of Diabetes-Induced Birth Defects. Journal of the Society for Gynecologic Investigation 13:1, pages 2-10.
Crossref
Crossref
. 2006. Molekulare Pharmakologie und Toxikologie. Molekulare Pharmakologie und Toxikologie
153
259
.
Jana Navarová, Eduard Ujházy, Michal Dubovický & Mojmír Mach. (2005) Phenytoin induced oxidative stress in pre- and postnatal rat development - effect of vitamin E on selective biochemical variables. Biomedical Papers 149:2, pages 325-328.
Crossref
Crossref
Grazyna M. Kalabis, Alice Kostaki, Marcus H. Andrews, Sophie Petropoulos, William Gibb & Stephen G. Matthews. (2005) Multidrug Resistance Phosphoglycoprotein (ABCB1) in the Mouse Placenta: Fetal Protection1. Biology of Reproduction 73:4, pages 591-597.
Crossref
Crossref
Arun Kulkarni. 2005. Developmental and Reproductive Toxicology. Developmental and Reproductive Toxicology
525
570
.
Winnie Jeng, Andrea W. Wong, Ryan Ting-A-Kee & Peter G. Wells. (2005) Methamphetamine-enhanced embryonic oxidative DNA damage and neurodevelopmental deficits. Free Radical Biology and Medicine 39:3, pages 317-326.
Crossref
Crossref
Enrica Biagiotti, Paola Ferri, Ralf Dringen, Paolo Del Grande & Paolino Ninfali. (2005) Glucose‐6‐phosphate dehydrogenase and NADPH‐consuming enzymes in the rat olfactory bulb. Journal of Neuroscience Research 80:3, pages 434-441.
Crossref
Crossref
Paola Ferri, Enrica Biagiotti, Patrizia Ambrogini, Spartaco Santi, Paolo Del Grande & Paolino Ninfali. (2005) NADPH-consuming enzymes correlate with glucose-6-phosphate dehydrogenase in Purkinje cells: an immunohistochemical and enzyme histochemical study of the rat cerebellar cortex. Neuroscience Research 51:2, pages 185-197.
Crossref
Crossref
Lewis B. Holmes, Brent A. Coull, Jon Dorfman & Peter B. Rosenberger. (2005) The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs. The Journal of Pediatrics 146:1, pages 118-122.
Crossref
Crossref
. 2005. Epilepsie, Schwangerschaft und Fertilität. Epilepsie, Schwangerschaft und Fertilität
79
101
.
Sonja Kasapinovic, Gordon P. McCallum, Michael J. Wiley & Peter G. Wells. (2004) The peroxynitrite pathway in development: Phenytoin and benzo[a]pyrene embryopathies in inducible nitric oxide synthase knockout mice. Free Radical Biology and Medicine 37:11, pages 1703-1711.
Crossref
Crossref
Amanda K. Shaw, Claire Infante-Rivard & Howard I. Morrison. (2004) Use of medication during pregnancy and risk of childhood leukemia (Canada). Cancer Causes and Control 15:9, pages 931-937.
Crossref
Crossref
Tami L. Thomae, Edward Glover & Christopher A. Bradfield. (2004) A Maternal Ahr Null Genotype Sensitizes Embryos to Chemical Teratogenesis. Journal of Biological Chemistry 279:29, pages 30189-30194.
Crossref
Crossref
J.Steven Leeder. (2004) Translating pharmacogenetics and pharmacogenomics into drug development for clinical pediatrics and beyond. Drug Discovery Today 9:13, pages 567-573.
Crossref
Crossref
Peter G. Wells, Peter I. Mackenzie, Jayanta Roy Chowdhury, Chantal Guillemette, Philip A. Gregory, Yuji Ishii, Antony J. Hansen, Fay K. Kessler, Perry M. Kim, Namita Roy Chowdhury & Joseph K. Ritter. (2004) GLUCURONIDATION AND THE UDP-GLUCURONOSYLTRANSFERASES IN HEALTH AND DISEASE. Drug Metabolism and Disposition 32:3, pages 281-290.
Crossref
Crossref
Jae-Hyug YangYon-Ju KimJin-Hoon ChungMoon-Young KimHyun-Mee RyuHyun-Kyong AhnJung-Yul HanSoon-Ha YangAhm KimHyun-Se KimPyo-Jong LeeSung-Soo KimYoung-Ju KimKyung-Sim KohJong-Chul ShinYong-Kun ChoBo-Hyun Yoon. (2004) A Multi-center Study for Birth Defect Monitoring Systems in Korea. Journal of Korean Medical Science 19:4, pages 509.
Crossref
Crossref
Gian Mario Tiboni, Franca Giampietro, Stefania Angelucci, Pasquale Moio, Umberto Bellati & Carmine Di Ilio. (2003) Additional investigation on the potentiation of phenytoin teratogenicity by fluconazole. Toxicology Letters 145:3, pages 219-229.
Crossref
Crossref
Helen M. Lyon, Lewis B. Holmes & Taosheng Huang. (2003) Multiple congenital anomalies associated with in utero exposure of phenytoin: Possible hypoxic ischemic mechanism?. Birth Defects Research Part A: Clinical and Molecular Teratology 67:12, pages 993-996.
Crossref
Crossref
James L Gardner, Adriana M Doi, Robert T Pham, Christiaan M Huisden & Evan P Gallagher. (2003) Ontogenic differences in human liver 4-hydroxynonenal detoxification are associated with in vitro injury to fetal hematopoietic stem cells. Toxicology and Applied Pharmacology 191:2, pages 95-106.
Crossref
Crossref
Rebecca R. Laposa, Jeffrey T. Henderson & Peter G. Wells. (2003)
Tetracycline‐dependent regulation of
formamidopyrimidine DNA glycosylase
in transgenic mice conditionally reduces oxidative DNA damage
in vivo
. The FASEB Journal 17:10, pages 1343-1345.
Crossref
Crossref
J Steven Leeder. (2003) Developmental and pediatric pharmacogenomics. Pharmacogenomics 4:3, pages 331-341.
Crossref
Crossref
T. I. Chang, M. Horal, S. K. Jain, F. Wang, R. Patel & M. R. Loeken. (2003) Oxidant regulation of gene expression and neural tube development: Insights gained from diabetic pregnancy on molecular causes of neural tube defects. Diabetologia 46:4, pages 538-545.
Crossref
Crossref
Lan Na, Maria Wartenberg, Heinz Nau, Jürgen Hescheler & Heinrich Sauer. (2003) Anticonvulsant valproic acid inhibits cardiomyocyte differentiation of embryonic stem cells by increasing intracellular levels of reactive oxygen species. Birth Defects Research Part A: Clinical and Molecular Teratology 67:3, pages 174-180.
Crossref
Crossref
HI OrupJrJr, LB Holmes, DA Keith & BA Coull. (2003)
Craniofacial skeletal deviations following
in utero
exposure to the anticonvulsant phenytoin: monotherapy and polytherapy
. Orthodontics & Craniofacial Research 6:1, pages 2-19.
Crossref
Crossref
Camilla Barrett & Alan Richens. (2003) Epilepsy and pregnancy: Report of an Epilepsy Research Foundation Workshop. Epilepsy Research 52:3, pages 147-187.
Crossref
Crossref
Antonio F Machado, William J. Scott & Michael D. Collins. 2003. Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles. Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles
379
406
.
TOUFAN PARMAN & PETER G. WELLS. (2002)
Embryonic prostaglandin H synthase‐2 (PHS‐2) expression and benzo[
α
]pyrene teratogenicity in PHS‐2 knockout mice
1
. The FASEB Journal 16:9, pages 1001-1009.
Crossref
Crossref
Shin-Ichi Togashi, Noriko Takahashi, Masanori Iwama, Satoshi Watanabe, Kayoko Tamagawa & Tetsuya Fukui. (2002) Antioxidative Collagen-Derived Peptides In Human-Placenta Extract. Placenta 23:6, pages 497-502.
Crossref
Crossref
Aqiba Bokhari, Brent A. Coull & Lewis B. Holmes. (2002) Effect of prenatal exposure to anticonvulsant drugs on dermal ridge patterns of fingers. Teratology 66:1, pages 19-23.
Crossref
Crossref
Evan P. Gallagher & James L. Gardner. (2002) Comparative expression of two alpha class glutathione S-transferases in human adult and prenatal liver tissues. Biochemical Pharmacology 63:11, pages 2025-2036.
Crossref
Crossref
Adriana M. Doi, Paula E. Patterson & Evan P. Gallagher. (2002) Variability in Aflatoxin B1–Macromolecular Binding and Relationship to Biotransformation Enzyme Expression in Human Prenatal and Adult Liver. Toxicology and Applied Pharmacology 181:1, pages 48-59.
Crossref
Crossref
David J. Hoffman. (2002) Role of selenium toxicity and oxidative stress in aquatic birds. Aquatic Toxicology 57:1-2, pages 11-26.
Crossref
Crossref
YILDIZ DINCER, ZEYNEP ALADEMIR, VEDAT HAMURYUDAN, IZZET FRESKO & TULAY AKCAY. (2002) Superoxide Dismutase Activity and Glutathione System in Erythrocytes of Men with Behchet's Disease.. The Tohoku Journal of Experimental Medicine 198:3, pages 191-195.
Crossref
Crossref
Masaaki Miyata, Etsuko Tamura & Yasushi Yamazoe. (2002) Development of an In Vitro System Detecting Pro-embryotoxin. Japanese Journal of Pharmacology 89:3, pages 320-323.
Crossref
Crossref
M. J. Beck, C. McLellan, R. L.-F. Lightle, M. A. Philbert & C. Harris. (2001) Spatial Glutathione and Cysteine Distribution and Chemical Modulation in the Early Organogenesis-Stage Rat Conceptus in Utero. Toxicological Sciences 62:1, pages 92-102.
Crossref
Crossref
Lewis B. Holmes, Elizabeth A. Harvey, Brent A. Coull, Kelly B. Huntington, Shahram Khoshbin, Ailish M. Hayes & Louise M. Ryan. (2001) The Teratogenicity of Anticonvulsant Drugs. New England Journal of Medicine 344:15, pages 1132-1138.
Crossref
Crossref
Christian Meierhofer, Stefan Dunzendorfer & Christian J. Wiedermann. (2001) Theoretical Basis for the Activity of Thalidomide. BioDrugs 15:10, pages 681-703.
Crossref
Crossref
John M. DeSesso, Catherine F. Jacobson, Anthony R. Scialli & Gerald C. Goeringer. (2000) Hydroxylamine moiety of developmental toxicants is associated with early cell death: A structure-activity analysis. Teratology 62:5, pages 346-355.
Crossref
Crossref
Fernanda Amicarelli, Gian Mario Tiboni, Sabrina Colafarina, Antonella Bonfigli, Elisabetta Iammarrone, Michele Miranda & Carmine Di Ilio. (2000) Antioxidant and GSH-related enzyme response to a single teratogenic exposure to the anticonvulsant phenytoin: Temporospatial evaluation. Teratology 62:2, pages 100-107.
Crossref
Crossref
N.D. Madhavan & K.A. Naidu. (2000) Purification and Partial Characterization of Peroxidase from Human Term Placenta of Non-smokers: Metabolism of Benzo(a)pyrene-7,8-dihydrodiol. Placenta 21:5-6, pages 501-509.
Crossref
Crossref
Don C Van Dyke, Vicki L Ellingrod, Mary J Berg, Jennifer R Niebyl, Andrea L Sherbondy & Dimitri G Trembath. (2016) Pharmacogenetic Screening for Susceptibility to Fetal Malformations in Women. Annals of Pharmacotherapy 34:5, pages 639-645.
Crossref
Crossref
Mark C.K. Lu, Mary D. Sammel, Robert H. Cleveland, Louise M. Ryan & Lewis B. Holmes. (2000) Digit effects produced by prenatal exposure to antiepileptic drugs. Teratology 61:4, pages 277-283.
Crossref
Crossref
CHRISTOPHER J. NICOL, JULIAN ZIELENSKI, LAP‐CHEE TSUI & PETER G. WELLS. (2000) An embryoprotective role for glucose‐6‐phosphate dehydrogenase in developmental oxidative stress and chemical teratogenesis. The FASEB Journal 14:1, pages 111-127.
Crossref
Crossref
Jason M Hansen, Edward W Carney & Craig Harris. (1999) Differential alteration by thalidomide of the glutathione content of rat vs. rabbit conceptuses in vitro. Reproductive Toxicology 13:6, pages 547-554.
Crossref
Crossref
G. Tscheudschilsuren, S. Hombach-Klonisch, A. Küchenhoff, B. Fischer & T. Klonisch. (1999) Expression of the Arylhydrocarbon Receptor and the Arylhydrocarbon Receptor Nuclear Translocator during Early Gestation in the Rabbit Uterus. Toxicology and Applied Pharmacology 160:3, pages 231-237.
Crossref
Crossref
Toufan Parman, Michael J. Wiley & Peter G. Wells. (1999) Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity. Nature Medicine 5:5, pages 582-585.
Crossref
Crossref
Sean Ekins, Jukka Maenpää & Steven Wrighton. 1999. Handbook of Drug Metabolism. Handbook of Drug Metabolism
363
399
.
Louise M Winn & Peter G Wells. (1999) Maternal administration of superoxide dismutase and catalase in phenytoin teratogenicity1. Free Radical Biology and Medicine 26:3-4, pages 266-274.
Crossref
Crossref
Gian Mario Tiboni, Elisabetta Iammarrone, Franca Giampietro, Debora Lamonaca, Umberto Bellati & Carmine Di Ilio. (1999) Teratological interaction between the bis-triazole antifungal agent fluconazole and the anticonvulsant drug phenytoin. Teratology 59:2, pages 81-87.
Crossref
Crossref
F Amicarelli, A.M Ragnelli, P Aimola, A Bonfigli, S Colafarina, C Di Ilio & M Miranda. (1999) Age-dependent ultrastructural alterations and biochemical response of rat skeletal muscle after hypoxic or hyperoxic treatments. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1453:1, pages 105-114.
Crossref
Crossref
Matthias Radatz & Heinz Nau. 1999. Valproate. Valproate
91
128
.
Janee Gelineau-Van Waes, Gregory D. Bennett & Richard H. Finnell. (1999) Phenytoin-induced alterations in craniofacial gene expression. Teratology 59:1, pages 23-34.
Crossref
Crossref
Toufan Parman, Guoman Chen & Peter G. Wells. (1998) Free Radical Intermediates of Phenytoin and Related Teratogens. Journal of Biological Chemistry 273:39, pages 25079-25088.
Crossref
Crossref
Nira Ben-Jonathan & Rosemary Steinmetz. (1998) Xenoestrogens: The Emerging Story of Bisphenol A. Trends in Endocrinology & Metabolism 9:3, pages 124-128.
Crossref
Crossref
K JENSEN & S CATALANO. 1998. Handbook of Developmental Neurotoxicology. Handbook of Developmental Neurotoxicology
3
41
.
Mont R. Juchau & Hao Chen. 1998. Handbook of Developmental Neurotoxicology. Handbook of Developmental Neurotoxicology
321
337
.
Peter G Wells, Perry M Kim, Rebecca R Laposa, Christopher J Nicol, Toufan Parmana & Louise M Winn. (1997) Oxidative damage in chemical teratogenesis. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 396:1-2, pages 65-78.
Crossref
Crossref
Perry M. Kim, Umberto Deboni & Peter G. Wells. (1997) Peroxidase-Dependent Bioactivation and Oxidation of DNA and Protein in Benzo[a]Pyrene-Initiated Micronucleus Formation. Free Radical Biology and Medicine 23:4, pages 579-596.
Crossref
Crossref
Louise M. Winn & Peter G. Wells. (1997) Evidence for embryonic prostaglandin H synthase-catalyzed bioactivation and reactive oxygen species-mediated oxidation of cellular macromolecules in phenytoin and benzo[a]pyrene teratogenesis11Preliminary reports of this research were presented at the 33rd, 34th, and 35th Annual Meetings of the Society of Toxicology, Dallas, Texas, March 1994 (Toxicologist 14:164; 1994); Baltimore, Maryland, March 1995 (Toxicologist 15:276; 1995); and Anaheim, California, March 1996 (Fundam. Appl. Toxicol. 30(Suppl. No. 1, Part 2: The Toxicologist):244; 1996); and at the 27th Annual Symposium of the Society of Toxicology of Canada, Montreal, December 1994 (Proceedings, p. 77; 1994).. Free Radical Biology and Medicine 22:4, pages 607-621.
Crossref
Crossref
P. G. Wells, P. M. Kim, C. J. Nicol, T. Parman & L. M. Winn. 1997. Drug Toxicity in Embryonic Development I. Drug Toxicity in Embryonic Development I
453
518
.
Richard M. Eglen, Mont R. Juchau, Gillian Edwards, Arthur H. Weston, Helen Wise, M. D. Murray, D. Craig Brater, Olivier Valdenaire, Philippe Vernier & Annemarie PolakMont R. Juchau. 1997. Progress in Drug Research/Fortschritte der Arzneimittelforschung/Progrès des recherches pharmaceutiques. Progress in Drug Research/Fortschritte der Arzneimittelforschung/Progrès des recherches pharmaceutiques
25
92
.