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Leukemia & Lymphoma Volume 37, 2000 - Issue 1-2
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Original Article

Minimally Differentiated Acute Myeloid Leukemia (AML M0): Clinico-Biological Findings of 29 Cases

Nicola Cascavilla Department of Hematology, I.R.C.C.S.—“Casa Sollievo Della Sofferenza”, Hospital,—San Giovanni Rotondo, ItalyCorrespondence[email protected]
,
Lorella Melillo Department of Hematology, I.R.C.C.S.—“Casa Sollievo Della Sofferenza”, Hospital,—San Giovanni Rotondo, Italy
,
Giovanni D'arena Department of Hematology, I.R.C.C.S.—“Casa Sollievo Della Sofferenza”, Hospital,—San Giovanni Rotondo, Italy
,
Michele Mario Greco Department of Hematology, I.R.C.C.S.—“Casa Sollievo Della Sofferenza”, Hospital,—San Giovanni Rotondo, Italy
,
Angelo Michele Carella Department of Hematology, I.R.C.C.S.—“Casa Sollievo Della Sofferenza”, Hospital,—San Giovanni Rotondo, Italy
,
Maria Rosaria Sajeva Department of Hematology, I.R.C.C.S.—“Casa Sollievo Della Sofferenza”, Hospital,—San Giovanni Rotondo, Italy
,
Giovanni Perla Department of Hematology, I.R.C.C.S.—“Casa Sollievo Della Sofferenza”, Hospital,—San Giovanni Rotondo, Italy
,
Rosella Matera Department of Hematology, I.R.C.C.S.—“Casa Sollievo Della Sofferenza”, Hospital,—San Giovanni Rotondo, Italy
,
Maria Marta Minervini Department of Hematology, I.R.C.C.S.—“Casa Sollievo Della Sofferenza”, Hospital,—San Giovanni Rotondo, Italy
&
Mario Carotenuto Department of Hematology, I.R.C.C.S.—“Casa Sollievo Della Sofferenza”, Hospital,—San Giovanni Rotondo, Italy
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Pages 105-113 | Received 22 Aug 1999, Published online: 01 Jul 2009

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Angelo Michele Carella, Nicola Cascavilla, Michele Mario Greco, Lorella Melillo, Maria Rosaria Sajeva, Saverio Ladogana, Giovanni D'arena, Gianni Perla & Mario Carotenuto. (2001) Treatment of “Poor Risk” Acute Myeloid Leukemia with Fludarabine, Cytarabine and G-CSF (Flag Regimen): A Single Center Study. Leukemia & Lymphoma 40:3-4, pages 295-303.
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Swati Garg, Chandrakala Shanmukhaiah, Supreet Marathe, Prashant Mishra, Vunditi Babu Rao, Kanjaksha Ghosh & Manisha Madkaikar. (2016) Differential antigen expression and aberrant signaling via PI3/AKT, MAP/ERK, JAK/STAT, and Wnt/ β catenin pathways in Lin−/CD38−/CD34+ cells in acute myeloid leukemia . European Journal of Haematology 96:3, pages 309-317.
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Hsiao-Wen Kao, Der-Cherng Liang, Jin-Hou Wu, Ming-Chung Kuo, Po-Nan Wang, Chao-Ping Yang, Yu-Shu Shih, Tung-Huei Lin, Yu-Hui Huang & Lee-Yung Shih. (2014) Gene Mutation Patterns in Patients with Minimally Differentiated Acute Myeloid Leukemia. Neoplasia 16:6, pages 481-488.
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Alice Gougounon, Halima Abahssain, Lauren Rigollet, Mohamed Elhamri, Isabelle Tigaud, Youcef Chelghoum, Adriana Plesa, Charles Dumontet, Mauricette Michallet & Xavier Thomas. (2011) Minimally differentiated acute myeloid leukemia (FAB AML-M0): Prognostic factors and treatment effects on survival—A retrospective study of 42 adult cases. Leukemia Research 35:8, pages 1027-1031.
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Faramarz Naeim & P. Nagesh Rao. 2008. Hematopathology. Hematopathology 207 255 .
Mohamed Abdelhaleem. (2007) Frequent but nonrandom expression of lymphoid markers on de novo childhood acute myeloid leukemia. Experimental and Molecular Pathology 83:2, pages 259-263.
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Mohamed Abdelhaleem, Mary Shago, Ebrahim Sayeh & Oussama Abla. (2007) Childhood myeloid/natural killer precursor acute leukemia with novel chromosomal aberrations der(5)t(4;5)(q31;q31.3) and t(14;17)(q32;q23). Cancer Genetics and Cytogenetics 178:2, pages 141-143.
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Draga BarbaricTodd A. AlonzoRobert B. GerbingSoheil MeshinchiNyla A. HeeremaDorothy R. BarnardBeverly J. LangeWilliam G. WoodsRobert J. ArceciFranklin O. Smith. (2006) Minimally differentiated acute myeloid leukemia (FAB AML-M0) is associated with an adverse outcome in children: a report from the Children's Oncology Group, studies CCG-2891 and CCG-2961. Blood 109:6, pages 2314-2321.
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Morito Kurata, Maki Hasegawa, Yasunori Nakagawa, Shinya Abe, Kouhei Yamamoto, Kenshi Suzuki & Masanobu Kitagawa. (2006) Expression dynamics of drug resistance genes, multidrug resistance 1 (MDR1) and lung resistance protein (LRP) during the evolution of overt leukemia in myelodysplastic syndromes. Experimental and Molecular Pathology 81:3, pages 249-254.
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Fred G. Behm. 2010. Childhood Leukemias. Childhood Leukemias 150 209 .
Ulrike Bacher, Wolfgang Kern, Susanne Schnittger, Wolfgang Hiddemann, Claudia Schoch & Torsten Haferlach. (2005) Further correlations of morphology according to FAB and WHO classification to cytogenetics in de novo acute myeloid leukemia: a study on 2,235 patients. Annals of Hematology 84:12, pages 785-791.
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Mirjam Klaus, Torsten Haferlach, Susanne Schnittger, Wolfgang Kern, Wolfgang Hiddemann & Claudia Schoch. (2004) Cytogenetic profile in de novo acute myeloid leukemia with FAB subtypes M0, M1, and M2: a study based on 652 cases analyzed with morphology, cytogenetics, and fluorescence in situ hybridization. Cancer Genetics and Cytogenetics 155:1, pages 47-56.
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H.T Hassan. (2004) Ajoene (natural garlic compound): a new anti-leukaemia agent for AML therapy. Leukemia Research 28:7, pages 667-671.
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Juan Ramón González Garcı́a, Stefan K. Bohlander, Melva Gutiérrez Angulo, Marı́a Amparo Esparza Flores, Verónica Judith Picos Cárdenas, Juan Pablo Meza Espinoza, Marı́a de la Luz Ayala Madrigal & Horacio Rivera. (2004) A t(1;9)(q23.3∼q25;q34) affecting the ABL1 gene in a biphenotypic leukemia. Cancer Genetics and Cytogenetics 152:1, pages 81-83.
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E Paietta, D Neuberg, J M Bennett, G Dewald, J M Rowe, P A Cassileth, L Cripe, M S Tallman & P H Wiernik. (2003) Low expression of the myeloid differentiation antigen CD65s, a feature of poorly differentiated AML in older adults: study of 711 patients enrolled in ECOG trials. Leukemia 17:8, pages 1544-1550.
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Ritsuro Suzuki, Makoto Murata, Masahiro Kami, Shigeki Ohtake, Norio Asou, Yoshihisa Kodera, Masao Tomonaga, Yasufumi Masaki, Shuya Kusumoto, Jin Takeuchi, Shin Matsuda, Hisamaru Hirai, Seiichi Yorimitsu, Nobuyuki Hamajima, Masao Seto, Masanori Shimoyama, Ryuzo Ohno, Yasuo Morishima & Shigeo Nakamura. (2003) Prognostic Significance of CD7+CD56+ Phenotype and Chromosome 5 Abnormalities for Acute Myeloid Leukemia M0. International Journal of Hematology 77:5, pages 482-489.
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