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Original Article

Simultaneous Detection of BCL-2 Protein, Trisomy 12, Retinoblastoma and P53 Monoallelic Gene Deletions in B-Cell Chronic Lymphocytic Leukemia by Fluorescence in Situ Hybridization (FISH): Relation to Disease Status

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Pages 503-512 | Received 05 Jul 1999, Published online: 01 Jul 2009

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Viralkumar Patel, Lisa S. Chen, William G. Wierda, Kumudha Balakrishnan & Varsha Gandhi. (2014) Impact of bone marrow stromal cells on Bcl-2 family members in chronic lymphocytic leukemia. Leukemia & Lymphoma 55:4, pages 899-910.
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Amani Khorchid & Pierre Beauparlant. (2004) Bcl-2-targeted cancer therapeutics. Expert Opinion on Therapeutic Patents 14:6, pages 805-818.
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Articles from other publishers (15)

Hiwa K. Saaed, Matin A. Mahmood & Najmaddin Khoshnaw. (2017) Quantitative real time PCR analysis of apoptotic gene expression in chronic lymphocytic leukemia patients and their relationships with chemosensitivity. Applied Cancer Research 37:1.
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Ahmad Baraka, Shereen El Shorbagy, Ola M. Elfarargy, Rasha Haggag, Lobna A. Abdelaziz, Salah F. Elsayed & Khaled A. Elbana. (2017) Prognostic Significance of Apoptosis Regulators in B-Cell Chronic Lymphocytic Leukemia. Journal of Cancer Therapy 08:04, pages 360-385.
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Viralkumar Patel, Kumudha Balakrishnan & Varsha Gandhi. 2015. Multi-Targeted Approach to Treatment of Cancer. Multi-Targeted Approach to Treatment of Cancer 73 98 .
Flora Tzifi, Christina Economopoulou, Dimitrios Gourgiotis, Alexandros Ardavanis, Sotirios Papageorgiou & Andreas Scorilas. (2012) The Role of BCL2 Family of Apoptosis Regulator Proteins in Acute and Chronic Leukemias. Advances in Hematology 2012, pages 1-15.
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K‐John J. Cheung, Douglas E. Horsman & Randy D. Gascoyne. (2009) The significance of TP53 in lymphoid malignancies: mutation prevalence, regulation, prognostic impact and potential as a therapeutic target . British Journal of Haematology 146:3, pages 257-269.
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Fang Jia, Said Daibes Figueroa, Fabio Gallazzi, Baghavathy S. Balaji, Mark Hannink, Susan Z. Lever, Timothy J. Hoffman & Michael R. Lewis. (2008) Molecular Imaging of bcl-2 Expression in Small Lymphocytic Lymphoma Using 111 In-Labeled PNA–Peptide Conjugates . Journal of Nuclear Medicine 49:3, pages 430-438.
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Susan M. O'Brien, Charles C. Cunningham, Anatoliy K. Golenkov, Anna G. Turkina, Steven C. Novick & Kanti R. Rai. (2005) Phase I to II Multicenter Study of Oblimersen Sodium, a Bcl-2 Antisense Oligonucleotide, in Patients With Advanced Chronic Lymphocytic Leukemia. Journal of Clinical Oncology 23:30, pages 7697-7702.
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Lenka Šindelářová, Kyra Michalová, Zuzana Zemanová, Šárka Ransdorfová, Jana Březinová, Soňa Peková, Jiří Schwarz, Josef Karban & Eduard Cmunt. (2005) Incidence of chromosomal anomalies detected with FISH and their clinical correlations in B-chronic lymphocytic leukemia. Cancer Genetics and Cytogenetics 160:1, pages 27-34.
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Pierre Beauparlant & Gordon C. Shore. 2004. Cell Engineering. Cell Engineering 223 237 .
Shoshana Peller & Varda Rotter. (2003) TP53 in hematological cancer: Low incidence of mutations with significant clinical relevance. Human Mutation 21:3, pages 277-284.
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Richard J. KlasaAmanda M. Gillum, Robert E. Klem & Stanley R. Frankel. (2002) Oblimersen Bcl-2 Antisense: Facilitating Apoptosis in Anticancer Treatment. Antisense and Nucleic Acid Drug Development 12:3, pages 193-213.
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Utz Krug, Arnold Ganser & H Phillip Koeffler. (2002) Tumor suppressor genes in normal and malignant hematopoiesis. Oncogene 21:21, pages 3475-3495.
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Gislaine B. Oliveira, Fernanda G. Pereira, Konradin Metze & Irene Lorand‐Metze. (2002) Spontaneous apoptosis in chronic lymphocytic leukemia and its relationship to clinical and cell kinetic parameters. Cytometry 46:6, pages 329-335.
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John L. Frater, Karen F. McCarron, Jeffrey P. Hammel, Joel L. Shapiro, Michael L. Miller, Raymond R. Tubbs, James Pettay & Eric D. Hsi. (2001) Typical and Atypical Chronic Lymphocytic Leukemia Differ Clinically and Immunophenotypically. American Journal of Clinical Pathology 116:5, pages 655-664.
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Kunihiko Yoshioka & So Nakamura. (2001) Chromosome 9 and 17 Aberrations and p53 Gene Deletion Detected by Fluorescence in Situ Hybridization in Renal-Cell Carcinoma . Molecular Urology 5:1, pages 11-17.
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