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Leukemia & Lymphoma Volume 36, 2000 - Issue 3-4
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Original Article

Diagnosis and Treatment of Polycythemia Vera and Possible Future Study Designs of the PVSG

J. J. Michiels Goodheart Institute, Rotterdam, The Netherlands; Dept. of Clinical Hematology, Academic Medical Center, Amsterdam, The NetherlandsCorrespondence[email protected]
,
T. Barbui Dept. of Hematology, Ospedale Riuniti, Bergamo, Italy
,
G. Finazzi Dept. of Hematology, Ospedale Riuniti, Bergamo, Italy
,
S. M. Fuchtman Bone Marrow Transplant, Mount Sinai Medical Center, New York, USA
,
J. Kutti Dept. of Hematology, Sahlgrenska University Hospital, Göteborg, Sweden
,
J. D. Rain Dept. of Nuclear Medicine, Hôpital Saint Louis, Paris, France
,
R. T. Silver Dept. of Medicine, Division of Hematology/Oncology, Cornell University, New York, USA
,
A. Tefferi Internal Medicine Division of Hematology, Mayo Clinics, Rochester, MN, USA
&
J. Thiele Institute Pathology, University of Cologne, Germany
 show all
Pages 239-253 | Received 04 Jul 1999, Published online: 01 Jul 2009

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Juergen Thiele & Hans M. Kvasnicka. (2006) A critical reappraisal of the WHO classification of the chronic myeloproliferative disorders. Leukemia & Lymphoma 47:3, pages 381-396.
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Jan Jacques Michiels, Zwi N. Berneman, Wilfried Schroyens & Huub H. D. M. Van Vliet. (2004) Review. Platelets 15:2, pages 67-84.
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Francesco Passamonti & Mario Lazzarino. (2003) Treatment of Polycythemia Vera and Essential Thrombocythemia: The Role of Pipobroman. Leukemia & Lymphoma 44:9, pages 1483-1488.
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J. Thiele & H. M. Kvasnicka. (2001) Comparative Effects of Interferon and Hydroxyurea on Bone Marrow Fibrosis in Chronic Myelogenous Leukemia. Leukemia & Lymphoma 42:5, pages 855-862.
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Articles from other publishers (29)

Manuel M. Pérez Encinas, Marta Sobas, María Teresa Gómez‐Casares, Aitor Abuin Blanco, María Soledad Noya Pereira, José María Raya, Marcio M. Andrade‐Campos, Alberto Álvarez Larrán, Krzysztof Lewandowski, Szukalski Łukasz, Juan Carlos Hernández Boluda, Francisca Ferrer‐Marín, María Laura Fox, Aleksandra Gołos, Mercedes Gasior Kabat, Elena Magro Mazo, Anna Czyż, Alejandro Martín Martín, Beatriz Bellosillo Paricio, Celsa Quinteiro García, Jesús María González Martín & Ruth Stuckey. (2020) The risk of thrombosis in essential thrombocythemia is associated with the type of CALR mutation: A multicentre collaborative study . European Journal of Haematology 106:3, pages 371-379.
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A. N. Chepurnaya, G. Sh. Safuanova, V. I. Nikulicheva, T. Y. Lekhmus & A. R. Rakhmatullina. (2020) ERYTHROCYTOSES IN PATIENTS WITH DILATED AND ISHAEMIC CARDIOMYOPATHY. Russian Clinical Laboratory Diagnostics 65:4, pages 222-227.
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Jan Jacques Michiels & Hendrik De Raeve. (2019) The PVSG/WHO versus the Rotterdam European clinical, molecular and pathological diagnostic criteria for the classification of myeloproliferative disorders and myeloproliferative neoplasms (MPD/MPN): From Dameshek to Georgii, Vainchenker and Michiels 1950-2018. International Journal of Bone Marrow Research, pages 027-050.
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Michiels Jan Jacques. (2019) European Clinical Laboratory, Molecular and Pathological (ECMP) criteria for prefibrotic JAK2V617F-Thrombocythemia and Polycythemia Vera versus MPL515- and CALR-Thrombocythemia and Myelofibrosis: From Dameshek to Michiels 1950-2018. International Journal of Bone Marrow Research 2:1, pages 001-017.
Crossref
M Nakatake, B Monte-Mor, N Debili, N Casadevall, V Ribrag, E Solary, W Vainchenker & I Plo. (2011) JAK2V617F negatively regulates p53 stabilization by enhancing MDM2 via La expression in myeloproliferative neoplasms. Oncogene 31:10, pages 1323-1333.
Crossref
Kamal S. Saini, Mrinal M. Patnaik & Ayalew Tefferi. (2010) Polycythemia vera‐associated pruritus and its management. European Journal of Clinical Investigation 40:9, pages 828-834.
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Francesco PassamontiFrancisco CervantesAlessandro Maria VannucchiEnrica Morra, Elisa RumiArturo PereiraPaola GuglielmelliEster Pungolino, Marianna Caramella, Margherita MaffioliCristiana PascuttoMario LazzarinoMario CazzolaAyalew Tefferi. (2010) A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment). Blood 115:9, pages 1703-1708.
Crossref
Samuel J. Lin & Peirong Yu. (2009) Free Tissue Transfer in a Head and Neck Cancer Patient with Polycythemia Vera. Plastic and Reconstructive Surgery 124:1, pages 169e-170e.
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Isabelle PloMayuka NakatakeLaurent Malivert, Jean-Pierre de Villartay, Stéphane GiraudierJean-Luc VillevalLisa Wiesmuller & William Vainchenker. (2008) JAK2 stimulates homologous recombination and genetic instability: potential implication in the heterogeneity of myeloproliferative disorders. Blood 112:4, pages 1402-1412.
Crossref
Kentaro Yoshinaga, Naoki Mori, Yan-hua Wang, Kaori Tomita, Masayuki Shiseki & Toshiko Motoji. (2008) JAK2 V617F mutation is rare in idiopathic erythrocytosis: a difference from polycythemia vera. International Journal of Hematology 88:1, pages 82-87.
Crossref
T Ishii, Y Zhao, J Shi, S Sozer, R Hoffman & M Xu. (2007) T cells from patients with polycythemia vera elaborate growth factors which contribute to endogenous erythroid and megakaryocyte colony formation. Leukemia 21:12, pages 2433-2441.
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David Dingli & Ayalew Tefferi. (2006) Hydroxyurea: The drug of choice for polycythemia vera and essential thrombocythemia. Current Hematologic Malignancy Reports 1:2, pages 69-74.
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S Aksu, Y Beyazit, IC Haznedaroglu, M Kekilli, H Canpinar, M Misirlioğlu, A Uner, S Tuncer, N Sayinalp, Y Büyükasik, H Goker & OI Ozcebe. (2016) Enhanced Expression of the Local Haematopoietic Bone Marrow Renin-Angiotensin System in Polycythemia Rubra Vera. Journal of International Medical Research 33:6, pages 661-667.
Crossref
Isabelle Corre-Buscail, Danielle Pineau, Marjorie Boissinot & Sylvie Hermouet. (2005) Erythropoietin-independent erythroid colony formation by bone marrow progenitors exposed to interleukin-11 and interleukin-8. Experimental Hematology 33:11, pages 1299-1308.
Crossref
ULRICH STEIDL, THOMAS SCHROEDER, CHRISTIAN STEIDL, GUIDO KOBBE, THORSTEN GRAEF, SIMONE BORK, SABRINA PECHTEL, SLAWOMIR KLISZEWSKI, ANDREA KUENDGEN, ULRICH P. ROHR, ROLAND FENK, MICHAEL SCHROEDER, DETLEF HAASE, RAINER HAAS & RALF KRONENWETT. (2005) Distinct Gene Expression Pattern of Malignant Hematopoietic Stem and Progenitor Cells in Polycythemia Vera. Annals of the New York Academy of Sciences 1044:1, pages 94-108.
Crossref
Juergen Thiele, Hans Michael Kvasnicka & Volker Diehl. (2005) Bone marrow features of diagnostic impact in erythrocytosis. Annals of Hematology 84:6, pages 362-367.
Crossref
Chunhua Dai, Ik-Joo Chung & Sanford B. Krantz. (2005) Increased erythropoiesis in polycythemia vera is associated with increased erythroid progenitor proliferation and increased phosphorylation of Akt/PKB. Experimental Hematology 33:2, pages 152-158.
Crossref
Jürgen Thiele, Hans Michael Kvasnicka & Volker Diehl. (2005) Initial (Latent) Polycythemia vera with Thrombocytosis Mimicking Essential Thrombocythemia. Acta Haematologica 113:4, pages 213-219.
Crossref
Jorge Cortes & Hagop Kantarjian. (2004) Beyond chronic myelogenous leukemia. Cancer 100:10, pages 2064-2078.
Crossref
Enli LiuJaroslav JelinekYves D. PastoreYongli GuanJaroslav F. PrchalJosef T. Prchal. (2003) Discrimination of polycythemias and thrombocytoses by novel, simple, accurate clonality assays and comparison with PRV-1 expression and BFU-E response to erythropoietin. Blood 101:8, pages 3294-3301.
Crossref
J. J. Michiels, Z. Berneman, W. Schroyens & H. van Urk. (2003) Aspirin-responsive painful red, blue, black toe, or finger syndrome in polycythemia vera associated with thrombocythemia. Annals of Hematology 82:3, pages 153-159.
Crossref
Thomas Bachleitner-Hofmann, Elke Grumbeck & Heinz Gisslinger. (2003) Oral anticoagulants as secondary prophylaxis of thrombosis in patients with polycythemia vera: a retrospective analysis of 15 patients. Thrombosis Research 112:4, pages 229-232.
Crossref
Sylvie Hermouet, Anne Godard, Danielle Pineau, Isabelle Corre, Sylvie Raher, Eric Lippert & Yannick Jacques. (2002) ABNORMAL PRODUCTION OF INTERLEUKIN (IL)-11 AND IL-8 IN POLYCYTHAEMIA VERA. Cytokine 20:4, pages 178-183.
Crossref
Jan Jacques Michiels & Juergen Thiele. (2002) Clinical and Pathological Criteria for the Diagnosis of Essential Thrombocythemia, Polycythemia Vera, and Idiopathic Myelofibrosis (Agnogenic Myeloid Metaplasia). International Journal of Hematology 76:2, pages 133-145.
Crossref
Giuseppe Torgano, Clara Mandelli, Paolo Massaro, Carla Abbiati, Antonio Ponzetto, Giovanni Bertinieri, Stefano Ferrero Bogetto, Elisabetta Terruzzi & Roberto De Franchis. (2002) Gastroduodenal lesions in polycythaemia vera: frequency and role of Helicobacter pylori . British Journal of Haematology 117:1, pages 198-202.
Crossref
P. Michl, G. Spoettl, D. Engelhardt & M.M. Weber. (2001) Alterations of the insulin-like growth factor system in patients with polycythemia vera. Molecular and Cellular Endocrinology 181:1-2, pages 189-197.
Crossref
Chunhua DaiSanford B. Krantz. (2001) Increased expression of the INK4a/ARF locus in polycythemia vera. Blood 97:11, pages 3424-3432.
Crossref
J. Thiele, H.M. Kvasnicka, K. Muehlhausen, S. Walter, R. Zankovich & V. Diehl. (2001) Polycythemia rubra vera versus Secondary Polycythemias. A Clinicopathological Evaluation of Distinctive Features in 199 Patients. Pathology - Research and Practice 197:2, pages 77-84.
Crossref
D. de Miguel Llorente, J. García Suárez, M. López Rubio & C. Burgaleta Alonso de Ozalla. (2001) Síndromes mieloproliferativos crónicos no leucémicos (I). Medicine - Programa de Formación Médica Continuada Acreditado 8:52, pages 2764-2769.
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