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Thalidomide and lenalidomide as new therapeutics for the treatment of chronic lymphocytic leukemia

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Pages 27-38 | Received 03 Aug 2009, Accepted 19 Sep 2009, Published online: 07 Jan 2010

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Andrea Acebes-Huerta, Leticia Huergo-Zapico, Ana Pilar Gonzalez-Rodriguez, Azahara Fernandez-Guizan, Angel R. Payer, Alejandro L?pez-Soto & Segundo Gonzalez. (2014) Lenalidomide Induces Immunomodulation in Chronic Lymphocytic Leukemia and Enhances Antitumor Immune Responses Mediated by NK and CD4 T Cells. BioMed Research International 2014, pages 1-11.
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Domenico Ribatti. (2013) Angiogenesis as a treatment target in leukemia. International Journal of Hematologic Oncology 2:3, pages 229-242.
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Yi Xia, Rui-Nan Lu & Jianyong Li. (2012) Angiogenic factors in chronic lymphocytic leukemia. Leukemia Research 36:10, pages 1211-1217.
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Nianhang Chen, Lian Wen, Henry Lau, Sekhar Surapaneni & Gondi Kumar. (2011) Pharmacokinetics, metabolism and excretion of [14C]-lenalidomide following oral administration in healthy male subjects. Cancer Chemotherapy and Pharmacology 69:3, pages 789-797.
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Jessica M. McDaniel, Javier Pinilla-Ibarz & P. K. Epling-Burnette. (2012) Molecular Action of Lenalidomide in Lymphocytes and Hematologic Malignancies. Advances in Hematology 2012, pages 1-9.
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Tamara Miner Haygood, Edith M. Marom & Donna M. Weber. 2012. Oncologic Imaging: A Multidisciplinary Approach. Oncologic Imaging: A Multidisciplinary Approach 509 529 .
Arvind Arumainathan, Nagesh Kalakonda & Andrew R. Pettitt. (2011) Lenalidomide can be highly effective in chronic lymphocytic leukaemia despite T-cell depletion and deletion of chromosome 17p. European Journal of Haematology 87:4, pages 372-375.
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C. Patrick Reynolds, Min H. Kang, Stephen T. Keir, Richard Gorlick, E. Anders Kolb, Richard Lock, John M. Maris, Hernan Carol, Christopher L. Morton, Catherine A. Billups, Malcolm A. Smith & Peter J. Houghton. (2011) Initial testing of lenalidomide by the pediatric preclinical testing program. Pediatric Blood & Cancer 57:4, pages 606-611.
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Andrea Schnaiter & Stephan Stilgenbauer. (2011) Novel targeted treatment strategies for refractory chronic lymphocytic leukaemia. Therapeutic Advances in Hematology 2:4, pages 249-265.
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Sarah E. M. HermanRosa LapalombellaAmber L. GordonAsha RamanunniKristie A. BlumJeffrey JonesXiaoli ZhangBrian J. Lannutti, Kamal D. Puri, Natarajan MuthusamyJohn C. Byrd & Amy J. Johnson. (2011) The role of phosphatidylinositol 3-kinase-δ in the immunomodulatory effects of lenalidomide in chronic lymphocytic leukemia. Blood 117:16, pages 4323-4327.
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