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Leukemia & Lymphoma Volume 51, 2010 - Issue 3
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Original Articles: Clinical

A phase II study of alemtuzumab, fludarabine, cyclophosphamide, and doxorubicin (Campath-FCD) in peripheral T-cell lymphomas

Eckhart WeidmannKlinik für Onkologie und Hämatologie, Krankenhaus Nordwest, Frankfurt am Main, GermanyCorrespondence[email protected]
,
Georg HessDepartment of Hematology/Oncology, Johannes Gutenberg-University, Mainz, Germany
,
Kai U. ChowMedical Practice Center, Frankfurt am Main, Germany
,
Stefan W. KrauseDepartment of Hematology/Oncology, University Hospital Regensburg, Regensburg, Germany
,
Marion SubkleweCharité, Universitätsmedizin Berlin, Campus Virchow, Med. Klinik m. S. Hämatologie/Onkologie, Berlin, Germany
,
Judith KruseKlinik für Onkologie und Hämatologie, Krankenhaus Nordwest, Frankfurt am Main, Germany
,
Katja C. WeiselUniversity of Tübingen Medical Center, Department of Hematology, Oncology, and Immunology, Tübingen, Germany
,
Martin SoeklerUniversity of Tübingen Medical Center, Department of Hematology, Oncology, and Immunology, Tübingen, Germany
,
Soo-Zin KimDepartment of Internal Medicine II, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany
,
Simone NapieralskiKlinik für Hämatologie, Onkologie und Immunologie, Philipps-Universität, Marburg, Germany
,
Jürgen RechMedical Clinic 3 and Department of Clinical Immunology, University of Erlangen-Nuremberg, Germany
,
Martin DreylingDepartment of Internal Medicine III, Grosshadern Hospital, Ludwig-Maximilians-University, Munich, Germany
,
Elke JägerKlinik für Onkologie und Hämatologie, Krankenhaus Nordwest, Frankfurt am Main, Germany
&
Paris S. MitrouDepartment of Internal Medicine II, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany
 show all
Pages 447-455 | Received 02 Oct 2009, Accepted 22 Dec 2009, Published online: 08 Feb 2010

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Avyakta Kallam & James O. Armitage. (2020) Contemporary strategies to improve outcomes for peripheral T-cell lymphoma patients following the failure of first-line therapy. Expert Review of Hematology 13:7, pages 745-753.
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Natali Pflug, Paula Cramer, Sandra Robrecht, Jasmin Bahlo, Anne Westermann, Anna-Maria Fink, Alexandra Schrader, Petra Mayer, Sebastian Oberbeck, Till Seiler, Thorsten Zenz, Jan Dürig, Karl-Anton Kreuzer, Stephan Stilgenbauer, Barbara Eichhorst, Michael Hallek, Marco Herling & Georg Hopfinger. (2019) New lessons learned in T-PLL: results from a prospective phase-II trial with fludarabine–mitoxantrone–cyclophosphamide–alemtuzumab induction followed by alemtuzumab maintenance . Leukemia & Lymphoma 60:3, pages 649-657.
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Silvana Novelli, Pilar García-Muret, Jorge Sierra & Javier Briones. (2016) Alemtuzumab treatment for Sézary syndrome: A single-center experience. Journal of Dermatological Treatment 27:2, pages 179-181.
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Pier Luigi Zinzani, Paolo Corradini, Andrea Gallamini, Alberto Grossi, Mario Lazzarino, Monia Marchetti, Maurizio Martelli, Giuseppe Rossi & Umberto Vitolo. (2012) Overview of alemtuzumab therapy for the treatment of T-cell lymphomas. Leukemia & Lymphoma 53:5, pages 789-795.
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Ahmad S Halwani & Brian K Link. (2011) Chemotherapy and antibody combinations for relapsed/refractory non-Hodgkin’s lymphoma. Expert Review of Anticancer Therapy 11:3, pages 443-455.
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Articles from other publishers (23)

Sean Harrop, Chathuri Abeyakoon, Carrie Van Der Weyden & H. Miles Prince. (2021) Targeted Approaches to T-Cell Lymphoma. Journal of Personalized Medicine 11:6, pages 481.
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Caiqin Xie, Xian Li, Hui Zeng & Wenbin Qian. (2020) Molecular insights into pathogenesis and targeted therapy of peripheral T cell lymphoma. Experimental Hematology & Oncology 9:1.
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Jarosław Czyż. (2019) Postępowanie w chłoniakach z obwodowych limfocytów T i NK. Acta Haematologica Polonica 50:2, pages 57-64.
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Haley M. Simpson, Aki Furusawa, Kavitha Sadashivaiah, Curt I. Civin & Arnob Banerjee. (2018) STAT5 inhibition induces TRAIL/DR4 dependent apoptosis in peripheral T-cell lymphoma. Oncotarget 9:24, pages 16792-16806.
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Jun Ho Yi, Seok Jin Kim & Won Seog Kim. (2017) Recent advances in understanding and managing T-cell lymphoma. F1000Research 6, pages 2123.
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Yaping Zhang, Wei Xu, Hong Liu & Jianyong Li. (2016) Therapeutic options in peripheral T cell lymphoma. Journal of Hematology & Oncology 9:1.
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Pier Luigi Zinzani, Vijayveer Bonthapally, Dirk Huebner, Richard Lutes, Andy Chi & Stefano Pileri. (2016) Panoptic clinical review of the current and future treatment of relapsed/refractory T-cell lymphomas: Peripheral T-cell lymphomas. Critical Reviews in Oncology/Hematology 99, pages 214-227.
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Rena Buckstein, Graeme Fraser, Matthew Cheung, Vishal Kukreti, John Kuruvilla, Kevin Imrie, Eugenia Piliotis, Gregory Pond, Jolanta Windsor, Zeina Ghorab, Kevin Shuoprasad, Ruth Turner, Ralph M. Meyer, Kathy Pritchard, Scott Walker, Mark Levine & Michael Crump. (2016) Alemtuzumab and CHOP Chemotherapy for the Treatment of Aggressive Histology Peripheral T Cell Lymphomas: A Multi-Center Phase I Study. Clinical Lymphoma Myeloma and Leukemia 16:1, pages 18-28.e4.
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Anna Czyż. (2015) Postępy w leczeniu agresywnych chłoniaków z obwodowych komórek T. Acta Haematologica Polonica 46:2, pages 94-99.
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Peter Reimer. (2014) Treatment options for patients with relapsing and refractory peripheral T-cell lymphoma. International Journal of Hematologic Oncology 3:5, pages 343-352.
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Mehdi Hamadani, Sarah M. Abu Kar, Saad Z. Usmani, Bipin N. Savani, Ernesto Ayala & Mohamed A. Kharfan-Dabaja. (2014) Management of Relapses After Hematopoietic Cell Transplantation in T-Cell Non-Hodgkin Lymphomas. Seminars in Hematology 51:1, pages 73-86.
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C. Binder, M. Ziepert, M. Pfreundschuh, U. Dührsen, H. Eimermacher, A. Aldaoud, A. Rosenwald, M. Loeffler, N. Schmitz & L. Truemper. (2013) CHO(E)P-14 followed by alemtuzumab consolidation in untreated peripheral T cell lymphomas: final analysis of a prospective phase II trial. Annals of Hematology 92:11, pages 1521-1528.
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Georg Hopfinger, Raymonde Busch, Natali Pflug, Nicole Weit, Anne Westermann, Anna‐Maria Fink, Paula Cramer, Nina Reinart, Dirk Winkler, Günter Fingerle‐Rowson, Stephan Stilgenbauer, Hartmut Döhner, Gabriele Kandler, Barbara Eichhorst, Michael Hallek & Marco Herling. (2013) Sequential chemoimmunotherapy of fludarabine, mitoxantrone, and cyclophosphamide induction followed by alemtuzumab consolidation is effective in T‐cell prolymphocytic leukemia. Cancer 119:12, pages 2258-2267.
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Lapo Alinari, Pierluigi Porcu & Bertrand Coiffier. 2013. T-Cell Lymphomas. T-Cell Lymphomas 243 261 .
Rabah Al Mahmoud, Sheila Weitzman, Tal Schechter, Bo Ngan, Mohammed Abdelhaleem & Sarah Alexander. (2012) Peripheral T-cell Lymphoma in Children and Adolescents. Journal of Pediatric Hematology/Oncology 34:8, pages 611-616.
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Maher Abdul-Hay & Jasmine Zain. (2012) Peripheral T-cell lymphoma: pharmacotherapy overview. Clinical Investigation 2:4, pages 403-416.
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Kerry J. Savage. (2011) Therapies for Peripheral T-Cell Lymphomas. Hematology 2011:1, pages 515-524.
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Abeer N. AbouYabis, Pareen J. Shenoy, Rajni Sinha, Christopher R. Flowers & Mary Jo Lechowicz. (2011) A Systematic Review and Meta-Analysis of Front-line Anthracycline-Based Chemotherapy Regimens for Peripheral T-Cell Lymphoma. ISRN Hematology 2011, pages 1-14.
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Claire E. Dearden, Rod Johnson, Ruth Pettengell, Stephen Devereux, Kate Cwynarski, Sean Whittaker & Andrew McMillan. (2011) Guidelines for the management of mature T‐cell and NK‐cell neoplasms (excluding cutaneous T‐cell lymphoma). British Journal of Haematology 153:4, pages 451-485.
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Kieron Dunleavy, Richard L. Piekarz, Jasmine Zain, John E. Janik, Wyndham H. Wilson, Owen A. O'Connor & Susan E. Bates. (2010) New Strategies in Peripheral T-Cell Lymphoma: Understanding Tumor Biology and Developing Novel Therapies. Clinical Cancer Research 16:23, pages 5608-5617.
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Niels Murawski & Michael Pfreundschuh. (2010) New drugs for aggressive B-cell and T-cell lymphomas. The Lancet Oncology 11:11, pages 1074-1085.
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Margaret T. Kasner. (2010) Novel Targets for Treatment of Adult Acute Lymphocytic Leukemia. Current Hematologic Malignancy Reports 5:4, pages 207-212.
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Peter Reimer. (2010) Impact of Autologous and Allogeneic Stem Cell Transplantation in Peripheral T-Cell Lymphomas. Advances in Hematology 2010, pages 1-12.
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