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Asparaginase revisited

Pages 168-178 | Received 10 Jun 2010, Accepted 02 Nov 2010, Published online: 01 Feb 2011

Keep up to date with the latest research on this topic with citation updates for this article.

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Katrina Farrell, Andrew Fyfe, Jonathan Allan, R. Campbell Tait & Mike Leach. (2016) An antithrombin replacement strategy during asparaginase therapy for acute lymphoblastic leukemia is associated with a reduction in thrombotic events. Leukemia & Lymphoma 57:11, pages 2568-2574.
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Mabel Guzmán-Rodríguez, María Guadalupe Serna-Domínguez & Leticia Santos. (2014) Identification, heterologous expression and detection of enzymatic activity of an asparaginase from the archaeon Thermoplasma acidophilum. Biocatalysis and Biotransformation 32:5-6, pages 295-301.
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Wendy Stock, Dan Douer, Daniel J. DeAngelo, Martha Arellano, Anjali Advani, Lloyd Damon, Tibor Kovacsovics, Mark Litzow, Michael Rytting, Gautam Borthakur & Archie Bleyer. (2011) Prevention and management of asparaginase/pegasparaginase-associated toxicities in adults and older adolescents: recommendations of an expert panel. Leukemia & Lymphoma 52:12, pages 2237-2253.
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Judit Müller, Petra Egyed, Daniel Erdelyi, Krisztian Kovacs, Katalin Mudra, Sandor Szabo, Balint Egyed & Kovacs Gabor. (2023) Our Experiences with Asparaginase Activity Measurements in Children with Lymphoblastic Diseases. Children 10:7, pages 1160.
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Karen Dos Santos, Gildas Bertho, Cédric Caradeuc, Véronique Baud, Aurélie Montagne, Daniel Abergel, Nicolas Giraud & Mathieu Baudin. (2023) A Toolbox for Glutamine Use in Dissolution Dynamic Nuclear Polarization: from Enzymatic Reaction Monitoring to the Study of Cellular Metabolic Pathways and Imaging. ChemPhysChem 24:12.
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Line Stensig Lynggaard, Cecilie U Rank, Bodil Als-Nielsen, Sofie G Hoejfeldt, Mats Heyman, Kjeld Schmiegelow & Birgitte K Albertsen. (2023) PEG-asparaginase treatment regimens for acute lymphoblastic leukaemia in children: a network meta-analysis. Cochrane Database of Systematic Reviews 2023:5.
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Sanyukta Darnal, Vijeta Patial, Virender Kumar, Subhash Kumar, Vijay Kumar, Yogendra S. Padwad & Dharam Singh. (2023) Biochemical characterization of extremozyme L-asparaginase from Pseudomonas sp. PCH199 for therapeutics. AMB Express 13:1.
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S. S. Alexandrova, Y. A. Gladilina, M. V. Pokrovskaya, N. N. Sokolov & D. D. Zhdanov. (2022) Mechanisms of Development of Side Effects and Drug Resistance to Asparaginase and Ways to Overcome Them. Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry 16:3, pages 175-186.
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Luke Maese & Rachel E. Rau. (2022) Current Use of Asparaginase in Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma. Frontiers in Pediatrics 10.
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Sama J. AL-zuwaini, Faramarz Mehrnejad, Zahra Lotfi-Sousefi, Ali Hossein Rezayan & Mohammad Barshan-tashnizi. (2022) The process of L-asparaginase encapsulation by poly (lactic-co-glycolic acid) and methoxy poly (ethylene glycol): A molecular dynamics simulation study. Materials Today Communications 31, pages 103435.
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S.S. Alexandrova, Y.A. Gladilina, M.V. Pokrovskaya, N.N. Sokolov & D.D. Zhdanov. (2022) Mechanisms of development of side effects and drug resistance to asparaginase and ways to overcome them. Biomeditsinskaya Khimiya 68:2, pages 104-116.
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Amalia Papanikolopoulou, Nikolaos Syrigos, Louisa Vini, Maria Papasavva, Georgios Lazopoulos, Stelios Kteniadakis, Demetrios Spandidos, Adrianni Charpidou & Nikolaos Drakoulis. (2021) Use of oral glutamine in radiation‑induced adverse effects in patients with thoracic and upper aerodigestive malignancies: Results of a prospective observational study. Oncology Letters 23:1.
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Jacek Lubkowski & Alexander Wlodawer. (2021) Structural and biochemical properties of L‐asparaginase. The FEBS Journal 288:14, pages 4183-4209.
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Line Stensig Lynggaard, Cecilie U Rank, Bodil Als-Nielsen, Sofie G Hoejfeldt, Mats Heyman, Kjeld Schmiegelow & Birgitte K Albertsen. (2021) PEG-asparaginase treatment for acute lymphoblastic leukaemia in children: a network meta-analysis. Cochrane Database of Systematic Reviews 2021:6.
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V. I. Timofeev, N. E. Zhukhlistova & I. P. Kuranova. (2020) Molecular Packing of a Mutant of L-Asparaginase from Wolinella succinigenes in Two Crystal Modifications. Crystallography Reports 65:4, pages 586-592.
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V. I. Timofeev, N. E. Zhukhlistova & I. P. Kuranova. (2020) Features of the Three Dimensional Structure of the Mutant Form of Wolinella succinogenes L-Asparaginase in Complexes with L-Aspartic and L-Glutamic Acids. Russian Journal of Bioorganic Chemistry 46:2, pages 171-180.
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Agnes Magri, Thainá Pecorari, Matheus M. Pereira, Eduardo M. Cilli, Tamar L. Greaves & Jorge F. B. Pereira. (2019) Enhancing the Biocatalytic Activity of l -Asparaginase Using Aqueous Solutions of Cholinium-Based Ionic Liquids . ACS Sustainable Chemistry & Engineering 7:24, pages 19720-19731.
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Rajesh Kumar Kante, Silpa Somavarapu, Sandeep Vemula, Chandrika Kethineni, Maheshwara Reddy Mallu & Srinivasa Reddy Ronda. (2019) Production of Recombinant Human Asparaginase from Escherichia coli under Optimized Fermentation Conditions: Effect of Physicochemical Properties on Enzyme Activity. Biotechnology and Bioprocess Engineering 24:5, pages 824-832.
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Jen-Hsuan Chang, Kurt Yun Mou & Chung-Yuan Mou. (2019) Sleeping Beauty Transposon-Mediated Asparaginase Gene Delivery by a Nanoparticle Platform. Scientific Reports 9:1.
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Virender Kumar, Subhash Kumar, Sanyukta Darnal, Vijeta Patial, Anju Singh, Vikas Thakur, Sanjay Kumar & Dharam Singh. (2019) Optimized chromogenic dyes-based identification and quantitative evaluation of bacterial l-asparaginase with low/no glutaminase activity bioprospected from pristine niches in Indian trans-Himalaya. 3 Biotech 9:7.
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