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Leukemia & Lymphoma Volume 53, 2012 - Issue 5
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Research Article

Association of genetic variations in mTOR with risk of childhood acute lymphoblastic leukemia in a Chinese population

Lizhen HuangDepartment of Hematology and Oncology, The Affiliated Nanjing Children's Hospital of Nanjing Medical University, Nanjing, China
,
Jie HuangDepartment of Hematology and Oncology, The Affiliated Nanjing Children's Hospital of Nanjing Medical University, Nanjing, China
,
Peng WuDepartment of Hematology and Oncology, The Affiliated Nanjing Children's Hospital of Nanjing Medical University, Nanjing, China
,
Qian LiDepartment of Hematology and Oncology, The Affiliated Nanjing Children's Hospital of Nanjing Medical University, Nanjing, China
,
Liucheng RongDepartment of Hematology and Oncology, The Affiliated Nanjing Children's Hospital of Nanjing Medical University, Nanjing, China
,
Yao XueDepartment of Hematology and Oncology, The Affiliated Nanjing Children's Hospital of Nanjing Medical University, Nanjing, China
,
Qin LuDepartment of Hematology and Oncology, The Affiliated Nanjing Children's Hospital of Nanjing Medical University, Nanjing, China
,
Jie LiDepartment of Hematology and Oncology, The Affiliated Children's Hospital of Soochow University, Soochow, China
,
Na TongDepartment of Molecular and Genetic Toxicology, Cancer Center of Nanjing Medical University, Nanjing, China
,
Meilin WangDepartment of Molecular and Genetic Toxicology, Cancer Center of Nanjing Medical University, Nanjing, China
,
Zhengdong ZhangDepartment of Molecular and Genetic Toxicology, Cancer Center of Nanjing Medical University, Nanjing, China
&
Yongjun FangDepartment of Hematology and Oncology, The Affiliated Nanjing Children's Hospital of Nanjing Medical University, Nanjing, ChinaCorrespondence[email protected]
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Pages 947-951 | Received 03 Aug 2011, Accepted 24 Sep 2011, Published online: 05 Dec 2011

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Jianping Deng, Yao Xue, Yaping Wang, Jing Chen, Jie Li, Qin Lu, Meilin Wang, Na Tong, Zhengdong Zhang & Yongjun Fang. (2015) 10p12.31-12.2 variants and risk of childhood acute lymphoblastic leukemia in a Chinese population. Leukemia & Lymphoma 56:1, pages 175-178.
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Articles from other publishers (19)

Zhichao Min, Yuanyuan Mi, Zhiwei Lv, Yangyang Sun, Bowen Tang, Hao Wu, Ze Zhang, Hong Pan, Yujuan Zhang, Chao Lu, Li Zuo & Lifeng Zhang. (2022) Associations of Genetic Polymorphisms of mTOR rs2295080 T/G and rs1883965 G/A with Susceptibility of Urinary System Cancers. Disease Markers 2022, pages 1-16.
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Xiaoling Lu, Meitong Liu, Yuxiao Liao, Chao Huang, Longlong Chai, Yuchen Jin, Qiantao Xiong & Bifeng Chen. (2022) Meta-analysis of the association between mTORC1-related genes polymorphisms and cancer risk. Pathology - Research and Practice 229, pages 153696.
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Rostam Maruei‐Milan, Mohsen Saravani, Zahra Heidari, Mina Asadi‐Tarani & Saeedeh Salimi. (2020) Effects of the MTOR and AKT1 genes polymorphisms on papillary thyroid cancer development . IUBMB Life 72:12, pages 2601-2610.
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Guang-Hui Qi, Chun-Hui Wang, Hong-Ge Zhang, Jian-Guo Yu, Fei Ding, Zhi-Chao Song & Qing-Hua Xia. (2020) Comprehensive analysis of the effect of rs2295080 and rs2536 polymorphisms within the mTOR gene on cancer risk . Bioscience Reports 40:7.
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Qiuchen Chen, Xiaolan Deng, Xiaoyun Hu, Shu Guan, Miao He, Yilin Wang, Binbin Wei, Jing Zhang, Haishan Zhao, Weifan Yao, Feng Jin, Yong Liu, Jianjun Chen, Olufunmilayo I. Olapade, Huizhe Wu & Minjie Wei. (2019) Breast Cancer Risk–Associated SNPs in the mTOR Promoter Form De Novo KLF5- and ZEB1-Binding Sites that Influence the Cellular Response to Paclitaxel . Molecular Cancer Research 17:11, pages 2244-2256.
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Peri Husen, Katja Straub, Katharina Willuweit, Anna Hagemann, Heiner Wedemeyer, Hagen S. Bachmann & Kerstin Herzer. (2019) SNPs Within the MTOR Gene Are Associated With an Increased Risk of Developing De Novo Diabetes Mellitus Following the Administration of Everolimus in Liver Transplant Recipients. Transplantation Proceedings 51:6, pages 1962-1971.
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Jie Shi & Ying Luo. (2019) Effects of RHD gene polymorphisms on distinguishing weak D or DEL from RhD− in blood donation in a Chinese population . Molecular Genetics & Genomic Medicine, pages e00681.
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Zhen Zhang, Qiuchen Chen, Jing Zhang, Yilin Wang, Xiaoyun Hu, Sainan Yin, Miao He, Shu Guan, Wenyan Qin, Qinghuan Xiao, Haishan Zhao, Weifan Yao, Huizhe Wu & Minjie Wei. (2017) Associations of genetic polymorphisms in pTEN/AKT/mTOR signaling pathway genes with cancer risk: A meta-analysis in Asian population. Scientific Reports 7:1.
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Terri N. Iwata, Julita A. Ram?rez-Komo, Heon Park & Brian M. Iritani. (2017) Control of B lymphocyte development and functions by the mTOR signaling pathways. Cytokine & Growth Factor Reviews 35, pages 47-62.
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Wei Jiang, Wenjue Zhang, Lihong Wu, Lipin Liu, Yu Men, Jingbo Wang, Jun Liang, Zhouguang Hui, Zongmei Zhou, Nan Bi & Luhua Wang. (2017) MicroRNA-Related Polymorphisms in PI3K/Akt/mTOR Pathway Genes Are Predictive of Limited-Disease Small Cell Lung Cancer Treatment Outcomes. BioMed Research International 2017, pages 1-10.
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Jin Zining, Xu Lu, He Caiyun & Yuan Yuan. (2016) Genetic polymorphisms of mTOR and cancer risk: a systematic review and updated meta-analysis . Oncotarget 7:35, pages 57464-57480.
Crossref
Jinhong Zhu, Mengyun Wang, Jing He, Meiling Zhu, Jiu‐Cun Wang, Li Jin, Xiao‐Feng Wang, Ya‐Jun Yang, Jia‐Qing Xiang & Qingyi Wei. (2016) Polymorphisms in the AKT 1 and AKT 2 genes and oesophageal squamous cell carcinoma risk in an Eastern Chinese population . Journal of Cellular and Molecular Medicine 20:4, pages 666-677.
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Lucie Pouché, Jana Stojanova, Pierre Marquet & Nicolas Picard. (2016) New challenges and promises in solid organ transplantation pharmacogenetics: the genetic variability of proteins involved in the pharmacodynamics of immunosuppressive drugs. Pharmacogenomics 17:3, pages 277-296.
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Jinhong Zhu, Mengyun Wang, Meiling Zhu, Jin He, Jiu-Cun Wang, Li Jin, Xiao-Feng Wang, Jia-Qing Xiang & Qingyi Wei. (2015) Associations of PI3KR1 and mTOR Polymorphisms with Esophageal Squamous Cell Carcinoma Risk and Gene-Environment Interactions in Eastern Chinese Populations. Scientific Reports 5:1.
Crossref
Jianbo Shao, Ying Li, Peiwei Zhao, Xin Yue, Jun Jiang, Xiaohui Liang & Xuelian He. (2014) Association of mTOR Polymorphisms with Cancer Risk and Clinical Outcomes: A Meta-Analysis. PLoS ONE 9:5, pages e97085.
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Jing He, Meng-Yun Wang, Li-Xin Qiu, Mei-Ling Zhu, Ting-Yan Shi, Xiao-Yan Zhou, Meng-Hong Sun, Ya-Jun Yang, Jiu-Cun Wang, Li Jin, Ya-Nong Wang, Jin Li, Hong-Ping Yu & Qing-Yi Wei. (2013) Genetic variations of mTORC1 genes and risk of gastric cancer in an eastern chinese population. Molecular Carcinogenesis 52:S1, pages 70-79.
Crossref
Qiaoxin Li, Chengyuan Gu, Yao Zhu, Mengyun Wang, Yajun Yang, Jiucun Wang, Li Jin, Mei-Ling Zhu, Ting-Yan Shi, Jing He, Xiaoyan Zhou, Ding-wei Ye & Qingyi Wei. (2013) Polymorphisms in the mTOR Gene and Risk of Sporadic Prostate Cancer in an Eastern Chinese Population. PLoS ONE 8:8, pages e71968.
Crossref
Mei-Ling Zhu, Hongping Yu, Ting-Yan Shi, Jing He, Meng-Yun Wang, Qiao-Xin Li, Meng-Hong Sun, Li Jin, Ya-Jun Yang, Jiu-Cun Wang, Jia-Qing Xiang & Qing-Yi Wei. (2013) Polymorphisms in mTORC1 Genes Modulate Risk of Esophageal Squamous Cell Carcinoma in Eastern Chinese Populations. Journal of Thoracic Oncology 8:6, pages 788-795.
Crossref
Ming Xu, Guoquan Tao, Meiyun Kang, Yan Gao, Haixia Zhu, Weida Gong, Meilin Wang, Dongmei Wu, Zhengdong Zhang & Qinghong Zhao. (2013) A Polymorphism (rs2295080) in mTOR Promoter Region and Its Association with Gastric Cancer in a Chinese Population. PLoS ONE 8:3, pages e60080.
Crossref

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