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Leukemia & Lymphoma Volume 53, 2012 - Issue 12
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Research Article

Chronic myeloid leukemia stem cells display alterations in expression of genes involved in oxidative phosphorylation

Krzysztof FlisDepartment of Microbiology and Immunology, Temple University, School of Medicine, Philadelphia, PA, USA;Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland
,
David IrvinePaul O'Gorman Leukemia Research Centre, University of Glasgow, Glasgow, UK
,
Mhairi CoplandPaul O'Gorman Leukemia Research Centre, University of Glasgow, Glasgow, UK
,
Ravi BhatiaDivision of Hematopoietic Stem Cell and Leukemia Research, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA, USA
&
Tomasz SkorskiDepartment of Microbiology and Immunology, Temple University, School of Medicine, Philadelphia, PA, USACorrespondence[email protected]
Pages 2474-2478 | Received 19 Apr 2012, Accepted 19 May 2012, Published online: 18 Jun 2012

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Elias J. Jabbour, Timothy P. Hughes, Jorge E. Cortés, Hagop M. Kantarjian & Andreas Hochhaus. (2014) Potential mechanisms of disease progression and management of advanced-phase chronic myeloid leukemia. Leukemia & Lymphoma 55:7, pages 1451-1462.
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Fangfang Cai, Bibao Li, Jiang Li, Yong Ding, Dandan Xu & Fei Huang. (2023) Myricetin is effective and selective in inhibiting imatinib-resistant chronic myeloid leukemia stem and differentiated cells through targeting eIF4E. Anti-Cancer Drugs 34:5, pages 620-626.
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John Joson Ng & S. Tiong Ong. (2022) Therapy Resistance and Disease Progression in CML: Mechanistic Links and Therapeutic Strategies. Current Hematologic Malignancy Reports 17:6, pages 181-197.
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Sweta B. Patel, Travis Nemkov, Angelo D’Alessandro & Robert S. Welner. (2022) Deciphering Metabolic Adaptability of Leukemic Stem Cells. Frontiers in Oncology 12.
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Jayastu Senapati & Koji Sasaki. (2022) Chromosomal Instability in Chronic Myeloid Leukemia: Mechanistic Insights and Effects. Cancers 14:10, pages 2533.
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Annemarie Schwarz, Ingo Roeder & Michael Seifert. (2022) Comparative Gene Expression Analysis Reveals Similarities and Differences of Chronic Myeloid Leukemia Phases. Cancers 14:1, pages 256.
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Simone Mirabilii, Maria Rosaria Ricciardi & Agostino Tafuri. (2020) mTOR Regulation of Metabolism in Hematologic Malignancies. Cells 9:2, pages 404.
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Sylwia Flis, Ewelina Bratek, Tomasz Chojnacki, Marlena Piskorek & Tomasz Skorski. (2019) Simultaneous Inhibition of BCR-ABL1 Tyrosine Kinase and PAK1/2 Serine/Threonine Kinase Exerts Synergistic Effect against Chronic Myeloid Leukemia Cells. Cancers 11:10, pages 1544.
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Jennifer Fraszczak, Charles Vadnais, Marissa Rashkovan, Julie Ross, Hugues Beauchemin, Riyan Chen, Damien Grapton, Cyrus Khandanpour & Tarik Möröy. (2018) Reduced expression but not deficiency of GFI1 causes a fatal myeloproliferative disease in mice. Leukemia 33:1, pages 110-121.
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Rodrigo Prieto-Bermejo, Marta Romo-González, Alejandro Pérez-Fernández, Carla Ijurko & Ángel Hernández-Hernández. (2018) Reactive oxygen species in haematopoiesis: leukaemic cells take a walk on the wild side. Journal of Experimental & Clinical Cancer Research 37:1.
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Kamilla M.E. Laidlaw, Samuel Berhan, Suhu Liu, Giovannino Silvestri, Tessa L. Holyoake, David A. Frank, Bharat Aggarwal, Michael Y. Bonner, Danilo Perrotti, Heather G. Jørgensen & Jack L. Arbiser. (2016) Cooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia. Oncotarget 7:32, pages 51651-51664.
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Philippa C. May, Jamshid S. Khorashad, Mary Alikian, Danilo Perrotti & Alistair G. Reid. 2016. The Genetic Basis of Haematological Cancers. The Genetic Basis of Haematological Cancers 312 358 .
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Elzbieta Pawlowska & Janusz Blasiak. (2015) DNA Repair—A Double-Edged Sword in the Genomic Stability of Cancer Cells—The Case of Chronic Myeloid Leukemia. International Journal of Molecular Sciences 16:11, pages 27535-27549.
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Mary E. Irwin, Blake P. Johnson, Roxsan Manshouri, Hesham M. Amin & Joya Chandra. (2015) A NOX2/Egr-1/Fyn pathway delineates new targets for TKI-resistant malignancies. Oncotarget 6:27, pages 23631-23646.
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Marta E. Capala, Henny Maat, Francesco Bonardi, Vincent van den Boom, Jeroen Kuipers, Edo Vellenga, Ben N. G. Giepmans & Jan Jacob Schuringa. (2015) Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2. PLOS ONE 10:5, pages e0128585.
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L Truitt, C Hutchinson, J F DeCoteau & C R Geyer. (2014) Chaetocin antileukemia activity against chronic myelogenous leukemia cells is potentiated by bone marrow stromal factors and overcomes innate imatinib resistance. Oncogenesis 3:10, pages e122-e122.
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Emmanuelle Charafe-Jauffret, Christophe Ginestier, François Bertucci, Olivier Cabaud, Julien Wicinski, Pascal Finetti, Emmanuelle Josselin, José Adelaide, Tien-Tuan Nguyen, Florence Monville, Jocelyne Jacquemier, Jeanne Thomassin-Piana, Guillaume Pinna, Aurélie Jalaguier, Eric Lambaudie, Gilles Houvenaeghel, Luc Xerri, Annick Harel-Bellan, Max Chaffanet, Patrice Viens & Daniel Birnbaum. (2013) ALDH1-Positive Cancer Stem Cells Predict Engraftment of Primary Breast Tumors and Are Governed by a Common Stem Cell Program. Cancer Research 73:24, pages 7290-7300.
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Jonathan M. Gerber, Jessica L. Gucwa, David Esopi, Meltem Gurel, Michael C. Haffner, Milada Vala, William G. Nelson, Richard J. Jones & Srinivasan Yegnasubramanian. (2013) Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations. Oncotarget 4:5, pages 715-728.
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Ross Kinstrie & Mhairi Copland. (2012) Targeting Chronic Myeloid Leukemia Stem Cells. Current Hematologic Malignancy Reports 8:1, pages 14-21.
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