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Leukemia & Lymphoma Volume 53, 2012 - Issue 12
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Research Article

Synergistic/additive interaction of valproic acid with bortezomib on proliferation and apoptosis of acute myeloid leukemia cells

Danian NieDepartment of Hematology, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China
,
Kezhi HuangDepartment of Hematology, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China
,
Songmei YinDepartment of Hematology, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, ChinaCorrespondence[email protected] [email protected]
,
Yiqing LiDepartment of Hematology, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, ChinaCorrespondence[email protected] [email protected]
,
Shuangfeng XieDepartment of Hematology, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China
,
Liping MaDepartment of Hematology, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China
,
Xiuju WangDepartment of Hematology, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China
,
Yudan WuDepartment of Hematology, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China
&
Jie XiaoDepartment of Hematology, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China
 show all
Pages 2487-2495 | Received 20 Mar 2012, Accepted 23 May 2012, Published online: 18 Jun 2012

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Muneera Al-Hussaini & John F DiPersio. (2014) Small molecule inhibitors in acute myeloid leukemia: from the bench to the clinic. Expert Review of Hematology 7:4, pages 439-464.
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Denise Niewerth, Ilse Dingjan, Jacqueline Cloos, Gerrit Jansen & Gertjan Kaspers. (2013) Proteasome inhibitors in acute leukemia. Expert Review of Anticancer Therapy 13:3, pages 327-337.
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Articles from other publishers (16)

Øystein Bruserud, Galina Tsykunova, Maria Hernandez-Valladares, Hakon Reikvam & Tor Henrik Anderson Tvedt. (2021) Therapeutic Use of Valproic Acid and All-Trans Retinoic Acid in Acute Myeloid Leukemia—Literature Review and Discussion of Possible Use in Relapse after Allogeneic Stem Cell Transplantation. Pharmaceuticals 14:5, pages 423.
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San José-Enériz, Gimenez-Camino, Agirre & Prosper. (2019) HDAC Inhibitors in Acute Myeloid Leukemia. Cancers 11:11, pages 1794.
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Yun Liu, Wen-Jing Huang, Min-Ting Lin, Jia-Jun Li & Jian-Ye Zhang. 2019. Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy. Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy 207 228 .
Danian Nie, Kezhi Huang, Songmei Yin, Yiqing Li, Shuangfeng Xie, Liping Ma, Xiuju Wang, Yudan Wu, Jie Xiao, Jieyu Wang, Wenjuan Yang & Hongyun Liu. (2018) KPT-330 inhibition of chromosome region maintenance 1 is cytotoxic and sensitizes chronic myeloid leukemia to Imatinib. Cell Death Discovery 4:1.
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Subbroto Saha, Yingfu Yin, Kyeongseok Kim, Gwang-Mo Yang, Ahmed Dayem, Hye Choi & Ssang-Goo Cho. (2017) Valproic Acid Induces Endocytosis-Mediated Doxorubicin Internalization and Shows Synergistic Cytotoxic Effects in Hepatocellular Carcinoma Cells. International Journal of Molecular Sciences 18:5, pages 1048.
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Alice Bertaina, Luciana Vinti, Luisa Strocchio, Stefania Gaspari, Roberta Caruso, Mattia Algeri, Valentina Coletti, Carmelo Gurnari, Mariateresa Romano, Maria Giuseppina Cefalo, Katia Girardi, Valentina Trevisan, Valentina Bertaina, Pietro Merli & Franco Locatelli. (2017) The combination of bortezomib with chemotherapy to treat relapsed/refractory acute lymphoblastic leukaemia of childhood. British Journal of Haematology 176:4, pages 629-636.
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C M Csizmar, D-H Kim & Z Sachs. (2016) The role of the proteasome in AML. Blood Cancer Journal 6:12, pages e503-e503.
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Maryam Moradi Binabaj, Seyed Ahmad Hosseini, Alireza Khoshbin Khoshnazar & Jahanbakhsh Asadi. (2015) The Simultaneous Effect of Valproic Acid and Gamma Radiation on Telomerase Activity and Bax and Bcl-2 Protein Levels in MCF-7 Breast Cancer Cell Line. Jundishapur Journal of Natural Pharmaceutical Products 10:3.
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Leila Haery, Ryan C. Thompson & Thomas D. Gilmore. (2015) Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy. Genes & Cancer 6:5-6, pages 184-213.
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QITIAN MU, QIULING MA, SHASHA LU, TING ZHANG, MENGXIA YU, XIN HUANG, JIAN CHEN & JIE JIN. (2014) 10058-F4, a c-Myc inhibitor, markedly increases valproic acid-induced cell death in Jurkat and CCRF-CEM T-lymphoblastic leukemia cells. Oncology Letters 8:3, pages 1355-1359.
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Mohamed-Salah Abaza, Abdul-Majeed Bahman & Raja'a Al-Attiyah. (2014) Valproic acid, an anti-epileptic drug and a histone deacetylase inhibitor, in combination with proteasome inhibitors exerts antiproliferative, pro-apoptotic and chemosensitizing effects in human colorectal cancer cells: Underlying molecular mechanisms. International Journal of Molecular Medicine.
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Jacqueline Cloos, Denise Niewerth & Gerrit Jansen. 2014. Resistance to Proteasome Inhibitors in Cancer. Resistance to Proteasome Inhibitors in Cancer 181 204 .
Hanne Fredly, Bjørn Tore Gjertsen & Øystein Bruserud. (2013) Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agents. Clinical Epigenetics 5:1.
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HUI CAO, YIZHI CHENG, LIANGSHUN YOU, JIEJING QIAN & WENBIN QIAN. (2013) Homoharringtonine and SAHA synergistically enhance apoptosis in human acute myeloid leukemia cells through upregulation of TRAIL and death receptors. Molecular Medicine Reports 7:6, pages 1838-1844.
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Xiaofei Li, Yanshuang Zhu, Huabin He, Lianqing Lou, Weiwei Ye, Yongxin Chen & Jinghe Wang. (2013) Synergistically killing activity of aspirin and histone deacetylase inhibitor valproic acid (VPA) on hepatocellular cancer cells. Biochemical and Biophysical Research Communications 436:2, pages 259-264.
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Xiao-Li Du & Qi Chen. (2013) Recent Advancements of Bortezomib in Acute Lymphocytic Leukemia Treatment. Acta Haematologica 129:4, pages 207-214.
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