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Leukemia & Lymphoma Volume 54, 2013 - Issue 11
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Research Article

Cytarabine, aclarubicin and granulocyte colony-stimulating factor regimen represents an effective and safe salvage regimen for patients with acute myeloid leukemia refractory to first course of induction chemotherapy

Hong-Hu ZhuPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China
,
Hao JiangPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China
,
Bin JiangPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China
,
Jin LuPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China
,
Qian JiangPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China
,
Li BaoPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China
,
Xiao-Hui ZhangPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China
,
Ya-Zhen QinPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China
&
Xiao-Jun HuangPeking University People's Hospital, Peking University Institute of Hematology, Beijing, ChinaCorrespondence[email protected]
 show all
Pages 2452-2457 | Received 28 Oct 2012, Accepted 11 Feb 2013, Published online: 02 Apr 2013

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Limin Li, Xiaoqian Zhang, Hongjuan Yu, Mingwen Zhang, Mengyuan Xu, Jie Liu, Yueyue Fu, Hongbin Meng, Chengfang Lyu, Xiaoxia Li & Jin Zhou. (2018) Low-dose hypomethylating agent decitabine in combination with aclacinomycin and cytarabine achieves a better outcome than standard FLAG chemotherapy in refractory/relapsed acute myeloid leukemia patients with poor-risk cytogenetics and mutations. OncoTargets and Therapy 11, pages 6863-6870.
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Yao-jia Shen, Yi Zhang, Jie Chang, Hua-feng Wang, Xing-nong Ye, Li Zhu, Jie Jin & Hong-hu Zhu. (2023) CAG (cytarabine, aclarubicin and granulocyte colony-stimulating factor) regimen for core binding factor acute myeloid leukaemia with measurable residual disease. Annals of Hematology 102:7, pages 1731-1738.
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Sining Liu, Qingya Cui, Haiping Dai, Baoquan Song, Wei Cui, Shengli Xue, Huiying Qiu, Miao Miao, Zhengming Jin, Caixia Li, Chengcheng Fu, Ying Wang, Aining Sun, Suning Chen, Xiaming Zhu, Depei Wu & Xiaowen Tang. (2021) Early T-Cell Precursor Acute Lymphoblastic Leukemia and T/Myeloid Mixed Phenotype Acute Leukemia Possess Overlapping Characteristics and Both Benefit From CAG-Like Regimens and Allogeneic Hematopoietic Stem Cell Transplantation. Transplantation and Cellular Therapy 27:6, pages 481.e1-481.e7.
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J. Y. Zhang, L. Li, W. Liu, Y. Jin, M. Zhao, Y. Zhou & Z. Fan. (2020) Comparison of efficacy of HCAG and CAG re-induction chemotherapy in elderly low- and intermediate-risk group patients diagnosed with acute myeloid leukemia. Clinical and Translational Oncology 23:1, pages 48-57.
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Meiqing Lei, Limin Liu & Depei Wu. (2019) Priming with GM-CSF instead of G-CSF enhances CAG-induced apoptosis of acute monocytic leukemia cells in vitro. Cancer Chemotherapy and Pharmacology 84:2, pages 265-273.
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Huasheng Liu, Xiaoning Wang, Hailing Zhang, Jincheng Wang, Ying Chen, Tiantian Ma, Jing Shi, Ya Kang, Jieying Xi, Mengchang Wang & Mei Zhang. (2019) Dynamic changes in the level of WT1 as an MRD marker to predict the therapeutic outcome of patients with AML with and without allogeneic stem cell transplantation. Molecular Medicine Reports.
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Meiqing Lei, Limin Liu, Zhiming Wang & Depei Wu. (2019) Efficacy of high-dose cytarabine and aclarubicin in combination with G-CSF regimen compared to intermediate/high-dose cytarabine and standard-dose cytarabine induction regimen for non-remission acute myeloid leukemia. Indian Journal of Cancer 56:2, pages 167.
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Daisuke Minakata, Shin-ichiro Fujiwara, Takashi Ikeda, Yumiko Toda, Shoko Ito, Kiyomi Mashima, Kento Umino, Hirofumi Nakano, Ryoko Yamasaki, Kaoru Morita, Yasufumi Kawasaki, Miyuki Sugimoto, Chihiro Yamamoto, Masahiro Ashizawa, Kaoru Hatano, Kazuya Sato, Iekuni Oh, Ken Ohmine, Kazuo Muroi & Yoshinobu Kanda. (2017) Relationship between white blood cell count elevation and clinical response after G-CSF priming chemotherapy for acute myeloid leukemia. International Journal of Hematology 106:3, pages 411-417.
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Qi Qu, Limin Liu, Yanming Zhang, Xiaoli Li & Depei Wu. (2015) Increasing aclarubicin dosage of the conventional CAG (low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor) regimen is more efficacious as a salvage therapy than CAG for relapsed/refractory acute myeloid leukemia. Leukemia Research 39:12, pages 1353-1359.
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Xiaoli Li, Limin Liu, Yanming Zhang, Qi Qu, Yao Yao, Tong Wang, Wenjing Jiao & Depei Wu. (2015) Efficacy of cytarabine, aclarubicin and granulocyte colony-stimulating factor (CAG) regimen compared to FLAG regimen for adult patients with relapsed/refractory Philadelphia chromosome-negative acute lymphoblastic leukemia. Leukemia Research 39:11, pages 1201-1206.
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Aneta Rogalska, Marzena Szwed & Błażej Rychlik. (2014) The Connection between the Toxicity of Anthracyclines and Their Ability to Modulate the P-Glycoprotein-Mediated Transport in A549, HepG2, and MCF-7 Cells. The Scientific World Journal 2014, pages 1-10.
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