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Leukemia & Lymphoma Volume 55, 2014 - Issue 3
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Letter

DNMT3A mutations at R882 hotspot are only found in major clones of acute myeloid leukemia

Kathrin E. BislingBrighton and Sussex Medical School, University of Sussex, Brighton, UK;Faculty of Medicine, Ludwig Maximilian University, Munich, Germany
,
John N. BrewinBrighton and Sussex Medical School, University of Sussex, Brighton, UK
,
Andrew P. McGovernBrighton and Sussex Medical School, University of Sussex, Brighton, UK
,
Gillian A. HorneBrighton and Sussex Medical School, University of Sussex, Brighton, UK
,
Tom RiderBrighton and Sussex Medical School, University of Sussex, Brighton, UK
,
Helen J. StewartBrighton and Sussex Medical School, University of Sussex, Brighton, UK
,
Bernard H. RamsahoyeInstitute of Genetics and Molecular Medicine, University of Edinburgh, UK
&
Timothy J. ChevassutBrighton and Sussex Medical School, University of Sussex, Brighton, UK;Department of Haematology, Royal Sussex County Hospital, Brighton, UKCorrespondence[email protected]
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Pages 711-714 | Received 12 Mar 2013, Accepted 31 May 2013, Published online: 25 Jul 2013

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Helen J. S. Stewart, Ella Shalit, Loryn Halliday, Dominic Morey & Timothy J. Chevassut. (2015) Acute myeloid leukemia cells exhibit selective down-regulation of DNMT3A isoform 2. Leukemia & Lymphoma 56:12, pages 3445-3448.
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Articles from other publishers (3)

John S. Welch. (2014) Mutation Position Within Evolutionary Subclonal Architecture in AML. Seminars in Hematology 51:4, pages 273-281.
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Velizar Shivarov, Milena Ivanova & Elissaveta Naumova. (2014) Rapid Detection of DNMT3A R882 Mutations in Hematologic Malignancies Using a Novel Bead-Based Suspension Assay with BNA(NC) Probes. PLoS ONE 9:6, pages e99769.
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Helen Jayne Susan Stewart, Gillian Abigail Horne, Sarah Bastow & Timothy James Telfer Chevassut. (2013) BRD 4 associates with p53 in DNMT 3A‐mutated leukemia cells and is implicated in apoptosis by the bromodomain inhibitor JQ 1 . Cancer Medicine 2:6, pages 826-835.
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