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Research Article

ASXL1 mutations are infrequent in young patients with primary acute myeloid leukemia and their detection has a limited role in therapeutic risk stratification

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Pages 1326-1331 | Received 21 Jun 2013, Accepted 04 Aug 2013, Published online: 09 Oct 2013

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Read on this site (7)

Jing Xu, Zhuanghui Hao, Xian Chen, Minglin Hong, Daniel muteb Muyey, Xiuhua Chen & Hongwei Wang. (2022) The characteristics and clinical prognosis analysis of ASXL1 mutations in Chinese adult patients with primary cytogenetically normal acute myeloid leukemia by next-generation sequencing. Leukemia & Lymphoma 63:10, pages 2321-2329.
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Yun Lin, Yaping Wang, Yi Zheng, Zechuan Wang, Yanni Wang & Shaoyuan Wang. (2020) Clinical characteristics and prognostic study of adult acute myeloid leukemia patients with ASXL1 mutations. Hematology 25:1, pages 446-456.
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Katerina Kakosaiou, Fotios Panitsas, Aggeliki Daraki, Maria Pagoni, Paraskevi Apostolou, Agapi Ioannidou, Ioanna Vlachadami, Theodoros Marinakis, Chara Giatra, Diamantina Vasilatou, Constantina Sambani, Vassiliki Pappa & Kalliopi N. Manola. (2018) ASXL1 mutations in AML are associated with specific clinical and cytogenetic characteristics. Leukemia & Lymphoma 59:10, pages 2439-2446.
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Yun Lin, Yi Zheng, Ze-Chuan Wang & Shao-Yuan Wang. (2016) Prognostic significance of ASXL1 mutations in myelodysplastic syndromes and chronic myelomonocytic leukemia: A meta-analysis. Hematology 21:8, pages 454-461.
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Hsin-An Hou & Hwei-Fang Tien. (2016) Mutations in epigenetic modifiers in acute myeloid leukemia and their clinical utility. Expert Review of Hematology 9:5, pages 447-469.
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Lisa Pleyer & Richard Greil. (2015) Digging deep into “dirty” drugs – modulation of the methylation machinery. Drug Metabolism Reviews 47:2, pages 252-279.
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Articles from other publishers (5)

Fatma Al-Bulushi, Rahma Al-Riyami, Zainab Al-Housni, Bushra Al-Abri & Murtadha Al-Khabori. (2022) Impact of mutations in epigenetic modifiers in acute myeloid leukemia: A systematic review and meta-analysis. Frontiers in Oncology 12.
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Ibolya Czegle, Austin L. Gray, Minjing Wang, Yan Liu, Jun Wang & Edina A. Wappler-Guzzetta. (2021) Mitochondria and Their Relationship with Common Genetic Abnormalities in Hematologic Malignancies. Life 11:12, pages 1351.
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Bas J. Wouters & Ruud Delwel. (2016) Epigenetics and approaches to targeted epigenetic therapy in acute myeloid leukemia. Blood 127:1, pages 42-52.
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Kareem Jamani & Carolyn Owen. (2015) Update on recurrent genetic aberrations in acute myeloid leukemia. International Journal of Hematologic Oncology 4:5, pages 179-190.
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Sophia Yohe. (2015) Molecular Genetic Markers in Acute Myeloid Leukemia. Journal of Clinical Medicine 4:3, pages 460-478.
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