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Leukemia & Lymphoma Volume 55, 2014 - Issue 6
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Research Article

Phase I study of GTI-2040, a ribonucleotide reductase antisense, with high dose cytarabine in patients with relapsed/refractory acute myeloid leukemia

Rebecca B. KlisovicDivision of Hematology, Department of Medicine
,
William BlumDivision of Hematology, Department of Medicine;The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA
,
Zhongfa LiuDivision of Pharmaceutics, College of Pharmacy
,
Zhiliang XieDivision of Pharmaceutics, College of Pharmacy
,
Cheryl KefauverThe Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA
,
Lenguyen HuynhDivision of Hematology, Department of Medicine
,
James A. ZwiebelNational Cancer Institute, Bethesda, MD, USA
,
Steven M. DevineDivision of Hematology, Department of Medicine;The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA
,
John C. ByrdDivision of Hematology, Department of Medicine;The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA
,
Michael R. GreverDivision of Hematology, Department of Medicine;The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA
,
Kenneth K. ChanDivision of Pharmaceutics, College of Pharmacy;The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA
&
Guido MarcucciDivision of Hematology, Department of Medicine;The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USACorrespondence[email protected]
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Pages 1332-1336 | Received 22 May 2013, Accepted 23 Aug 2013, Published online: 01 Nov 2013

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Mark H. Kirschbaum, Paul Frankel, Timothy W. Synold, Zhiliang Xie, Yun Yen, Leslie Popplewell, Robert Chen, Omar Aljitawi, Joseph M. Tuscano, Kenneth K. Chan & Edward M. Newman. (2016) A phase I pharmacodynamic study of GTI-2040, an antisense oligonucleotide against ribonuclotide reductase, in acute leukemias: a California Cancer Consortium study. Leukemia & Lymphoma 57:10, pages 2307-2314.
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Articles from other publishers (5)

Prithi Raguraman, Akilandeswari Ashwini Balachandran, Suxiang Chen, Sarah D. Diermeier & Rakesh N. Veedu. (2021) Antisense Oligonucleotide-Mediated Splice Switching: Potential Therapeutic Approach for Cancer Mitigation. Cancers 13:21, pages 5555.
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Yaqiong Zhan, Lushun Jiang, Xuehang Jin, Shuaibing Ying, Zhe Wu, Li Wang, Wei Yu, Jiepeng Tong, Li Zhang, Yan Lou & Yunqing Qiu. (2021) Inhibiting RRM2 to enhance the anticancer activity of chemotherapy. Biomedicine & Pharmacotherapy 133, pages 110996.
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Thomas Briot, Emilie Roger, Sylvain Thépot & Frederic Lagarce. (2018) Advances in treatment formulations for acute myeloid leukemia. Drug Discovery Today 23:12, pages 1936-1949.
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Abdullah Al Hasan & A.T.M. Zafrul Azam. 2018. Design of Nanostructures for Theranostics Applications. Design of Nanostructures for Theranostics Applications 341 436 .
Pedro Barata, Anil K. Sood & David S. Hong. (2016) RNA-targeted therapeutics in cancer clinical trials: Current status and future directions. Cancer Treatment Reviews 50, pages 35-47.
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