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Review Article

Treatment of splenic marginal zone lymphoma: should splenectomy be abandoned?

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Pages 1463-1470 | Received 18 Jul 2013, Accepted 12 Sep 2013, Published online: 06 Nov 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Nathan M Denlinger, Narendranath Epperla & Basem M William. (2018) Management of relapsed/refractory marginal zone lymphoma: focus on ibrutinib. Cancer Management and Research 10, pages 615-624.
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Christina Kalpadakis, Gerassimos A. Pangalis, Maria K. Angelopoulou, Sotirios Sachanas & Theodoros P. Vassilakopoulos. (2016) Current and emerging treatment approaches for splenic marginal zone lymphoma. Expert Opinion on Orphan Drugs 4:9, pages 897-905.
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Ana Muntañola, María Teresa Villalobos, Sonia González‐Villambrosia, María José Rodríguez‐Salazar, Ana Jiménez‐Ubieto, Gabriela Bastidas‐Mora, Raúl Córdoba, María Infante, María Jesús Vidal, Francisco Javier Díaz, Mónica Baile, Mariana Bastos‐Oreiro, Carlos Panizo, Juan Manuel Sancho, Belén Navarro, Tomás García, Lourdes Escoda, Pau Abrisqueta, María José Terol, Raquel de Campo, Pablo Mozas, Armando López‐Guillermo, Antonio Salar & Carlos Montalbán. (2023) Low‐risk HPLLs / ABC score patients with splenic marginal zone lymphoma can be safely managed without treatment: Results from a prospective Spanish study . British Journal of Haematology 202:4, pages 776-784.
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Zhen Yang, Lianshuang Liu, Kaiming Leng & Guangjun Shi. (2023) Time Trend Analysis of Splenectomy for Splenic Marginal Zone Lymphoma: Declining Surgery, Promising Survival. Annals of Surgical Oncology.
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Q. Riller, F. Cohen-Aubart & D. Roos-Weil. (2022) Lymphomes spléniques : diagnostic et prise en charge. La Revue de Médecine Interne 43:10, pages 608-616.
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Kyle C. Roche, Peter A. DeRosa, Min-Ling Liu, Victor E. Nava & Anita Aggarwal. (2022) Refractory Splenic Marginal Zone Lymphoma Responsive to Combination Venetoclax and Bortezomib (Velcade) (V2) Therapy. Current Oncology 29:6, pages 4117-4124.
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Roberto Castelli, Monica Balzarotti, Emanuele Salvi, Roberta Simona Rossi, Giorgio Lambertenghi Deliliers, Luigi Bergamaschini & Antonio Gidaro. (2021) Risk-tailored treatment of splenic marginal zone lymphoma. Anti-Cancer Drugs 33:1, pages e36-e42.
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Prashant Sinha & H. Leon Pachter. 2022. Chassin's Operative Strategy in General Surgery. Chassin's Operative Strategy in General Surgery 795 801 .
John J. Schmieg, Jeannie M. Muir, Nadine S. Aguilera & Aaron Auerbach. (2021) CD5-Negative, CD10-Negative Low-Grade B-Cell Lymphoproliferative Disorders of the Spleen. Current Oncology 28:6, pages 5124-5147.
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Catarina Dantas Rodrigues, Rita Pinho Peixeiro, Diana Viegas, Pedro Chorão, M Eduarda Couto, Cátia Lino Gaspar, João Paulo Fernandes, Daniela Alves, Lídia Alves Ribeiro, Pedro de Vasconcelos M, Ana Luísa Tomé, Margarida Badior, Henrique Coelho, Fernando Príncipe, Sérgio Chacim, Maria Gomes da Silva & Rita Coutinho. (2021) Clinical Characteristics, Treatment and Evolution of Splenic and Nodal Marginal Zone Lymphomas—Retrospective and Multicentric Analysis of Portuguese Centers. Clinical Lymphoma Myeloma and Leukemia 21:11, pages e839-e844.
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Ramazan SARI & Mehmet Zeki BULDANLI. (2021) Lenfoproliferatif hastalıklarda splenektomi endikasyonları ve klinik sonuçlarımızSplenectomy indications and clinical results in lymphoproliferative diseases. Turkish Journal of Clinics and Laboratory 12:1, pages 102-106.
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Shiyu Zhang, Zefeng Xuan, Liang Zhang, Jiahua Lu, Penghong Song & Shusen Zheng. (2020) Splenic marginal zone lymphoma: a case report and literature review. World Journal of Surgical Oncology 18:1.
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Luís Alberto de Pádua Covas Lage, Felipe Faganelli Caboclo dos Santos, Débora Levy, Frederico Rafael Moreira, Samuel Campanelli Freitas Couto, Hebert Fabrício Culler, Renata de Oliveira Costa, Vanderson Rocha & Juliana Pereira. (2020) Risk adapted approach: How to treat splenic marginal zone lymphoma in resource-poor settings? - The real-life experience of a Brazilian cancer treatment center. BMC Cancer 20:1.
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Ю.Л. Евстахевич, В.Е. Логинский, И.И. Евстахевич, М.М. Семерак, Г.Б. Лебедь, О.А. Петрончак, М.А. Вальчук & Я.И. Выговская. (2020) Hematologic and Surgical Outcomes of Splenectomy in Patients with Lymphoma of the Splenic Marginal Zone. Гематология. Трансфузиология. Восточная Европа:3, pages 293-310.
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Francesco Bertoni, Davide Rossi, Markus Raderer & Emanuele Zucca. (2020) Marginal Zone Lymphomas. The Cancer Journal 26:4, pages 336-347.
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Ryota Koyama, Nozomi Minagawa, Yoshiaki Maeda, Toshiki Shinohara & Tomonori Hamada. (2019) Splenic marginal zone lymphoma treated with laparoscopic splenectomy: A case report. International Journal of Surgery Case Reports 65, pages 288-291.
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Christina KalpadakisGerassimos A. PangalisSotirios SachanasPantelis TsirkinidisFlora N. KontopidouMaria MoschogiannisXanthi YiakoumisEfstathios KoulierisMaria N. DimopoulouStella I. KokkorisMarie-Christine KyrtsonisMarina P. Siakantaris, Gerassimos TsourouflisPenelope Korkolopoulou, Dimitra Rontogianni, Panagiotis TsaftaridisEleni PlataHelen A. PapadakiPanagiotis PanagiotidisMaria K. AngelopoulouTheodoros P. Vassilakopoulos. (2018) Rituximab monotherapy in splenic marginal zone lymphoma: prolonged responses and potential benefit from maintenance. Blood 132:6, pages 666-670.
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N. D. Kennedy, G. N. Lê, M. E. Kelly, T. Harding, K. Fadalla & D. C. Winter. (2017) Surgical management of splenic marginal zone lymphoma. Irish Journal of Medical Science (1971 -) 187:2, pages 343-347.
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Christina Kalpadakis, Gerassimos A. Pangalis, Maria K. Angelopoulou, Sotirios Sachanas & Theodoros P. Vassilakopoulos. (2018) Should rituximab replace splenectomy in the management of splenic marginal zone lymphoma?. Best Practice & Research Clinical Haematology 31:1, pages 65-72.
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Kazuya SASAKI, Toshiki SAKAMOTO, So MATSUI & Misao SAITO. (2018) A Growing Asymptomatic Splenic Marginal Zone Lymphoma Treated by Splenectomy—A Case Report—増大傾向を示し脾摘術を行った無症候性脾辺縁帯リンパ腫の1例. Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 79:10, pages 2175-2181.
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. 2018. Diagnostic Pathology: Blood and Bone Marrow. Diagnostic Pathology: Blood and Bone Marrow 774 779 .
Carlos A. Ramos. 2018. Hematology. Hematology 1277 1287.e6 .
Giacomo Pata, Michele Bartoli, Enrico Damiani, Stefano Solari, Antonella Anastasia, Chiara Pagani & Alessandra Tucci. (2017) Still a role for surgery as first-line therapy of splenic marginal zone lymphoma? Results of a prospective observational study. International Journal of Surgery 41, pages 143-149.
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Tayse Silva dos Santos, Renato Sampaio Tavares & Danielle Leão Cordeiro de Farias. (2017) Splenic marginal zone lymphoma: a literature review of diagnostic and therapeutic challenges. Revista Brasileira de Hematologia e Hemoterapia 39:2, pages 146-154.
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Christina Kalpadakis, Gerassimos A. Pangalis, Maria K. Angelopoulou & Theodoros P. Vassilakopoulos. (2017) Treatment of splenic marginal zone lymphoma. Best Practice & Research Clinical Haematology 30:1-2, pages 139-148.
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Yukiko Komeno, Naoki Shibuya, Hideki Uryu, Haruki Yamada, Takeo Toda, Masayuki Shibasaki, Shinji Kunishima, Kuniko Iihara & Tomiko Ryu. (2017) Splenic Marginal Zone Lymphoma with Acquired von Willebrand Syndrome Diagnosed via Splenic Bleeding. Internal Medicine 56:5, pages 557-562.
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Luca Arcaini, Davide Rossi & Marco Paulli. (2016) Splenic marginal zone lymphoma: from genetics to management. Blood 127:17, pages 2072-2081.
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Masanori AKADA, Michinaga TAKAHASHI, Kazumasa SEIJI, Tatsuya UENO, Sinji GOTO & Hiroo NAITO. (2016) A Case of a Massively Enlarged Spleen (Maximum Diameter 40 cm) Treated by Splenectomy following Splenic Arterial Embolization. Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 77:7, pages 1802-1807.
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Jessica Schering & Vijayalakshmi Donthireddy. (2016) Paraneoplastic Syndrome in Splenic Marginal Zone Lymphoma: A Rare Phenomenon of Paraplegia as an Atypical Presenting Manifestation. Case Reports in Hematology 2016, pages 1-3.
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Katharine H. Xing, Amrit Kahlon, Brian F. Skinnider, Joseph M. Connors, Randy D. Gascoyne, Laurie H. Sehn, Kerry J. Savage, Graham W. Slack, Tamara N. Shenkier, Richard Klasa, Alina S. Gerrie & Diego Villa. (2015) Outcomes in splenic marginal zone lymphoma: analysis of 107 patients treated in British Columbia. British Journal of Haematology 169:4, pages 520-527.
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Barbara Vannata, Anastasios Stathis & Emanuele Zucca. 2015. Non-Hodgkin Lymphoma. Non-Hodgkin Lymphoma 227 249 .
Amir BehdadNathanael G. Bailey. (2014) Diagnosis of Splenic B-Cell Lymphomas in the Bone Marrow: A Review of Histopathologic, Immunophenotypic, and Genetic Findings. Archives of Pathology & Laboratory Medicine 138:10, pages 1295-1301.
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