Advanced search
Publication Cover
Leukemia & Lymphoma Volume 56, 2015 - Issue 1
Submit an article Journal homepage
416
Views
25
CrossRef citations to date
0
Altmetric
Original Article: Clinical

Phase 1/2 Study of Ocaratuzumab, an Fc-Engineered Humanized Anti-CD20 Monoclonal Antibody, in Low-Affinity FcγRIIIa Patients with Previously Treated Follicular Lymphoma

Kristen N. GanjooStanford Cancer Center, Stanford, CA, USACorrespondence[email protected]
,
Sven de VosDavid Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA
,
Brad L. PohlmanCleveland Clinic – Taussig Cancer Institute, Cleveland, OH, USA
,
Ian W. FlinnSarah Cannon Research Institute, Nashville, TN, USA
,
Andres Forero-TorresUniversity of Alabama at Birmingham, Birmingham, AL, USA
,
Nathan H. EnasEli Lilly and Company, Indianapolis, IN, USA
,
Damien M. CronierEli Lilly and Company, Windlesham, United Kingdom
,
Nam H. DangDivision of Hematology/Oncology, University of Florida, Gainesville, FL, USA
,
Kenneth A. FoonCelgene Corporation, Summit, NJ, USA
,
Susan P. CarpenterApplied Molecular Evolution, San Diego, CA, USA
,
Christopher A. SlapakEli Lilly and Company, Indianapolis, IN, USA
,
Brian K. LinkHolden Comprehensive Cancer Center at University of Iowa, Iowa City, IA, USA
,
Mitchell R. SmithCleveland Clinic – Taussig Cancer Institute, Cleveland, OH, USA
,
Markus Y. MaparaColumbia University Medical Center, New York, NY, USA
&
James E. WooldridgeEli Lilly and Company, Indianapolis, IN, USA
 show all
Pages 42-48 | Received 18 Oct 2013, Accepted 30 Mar 2014, Published online: 14 Jul 2014

Citations (25)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Wade Chun-Wai Suen, Wayne Yuk-Wai Lee, Kam-Tong Leung, Xiao-Hua Pan & Gang Li. (2018) Natural Killer Cell-Based Cancer Immunotherapy: A Review on 10 Years Completed Clinical Trials. Cancer Investigation 36:8, pages 431-457.
Read now
Piotr Smolewski & Tadeusz Robak. (2015) The preclinical discovery of rituximab for the treatment of non-Hodgkin’s lymphoma. Expert Opinion on Drug Discovery 10:7, pages 791-808.
Read now
Anne-Laure Gagez & Guillaume Cartron. (2015) New anti-CD20 monoclonal antibodies: which is the best?. Leukemia & Lymphoma 56:1, pages 1-2.
Read now

Articles from other publishers (22)

Umesh Panwar, Mohammad Aqueel Khan, Chandrabose Selvaraj & Sanjeev Kumar Singh. 2024. Resistance to Anti-Cd20 Antibodies and Approaches for their Reversal. Resistance to Anti-Cd20 Antibodies and Approaches for their Reversal 3 29 .
Lu Tang, Zhongpei Huang, Heng Mei & Yu Hu. (2023) Immunotherapy in hematologic malignancies: achievements, challenges and future prospects. Signal Transduction and Targeted Therapy 8:1.
Crossref
Juan J. Mata-Molanes, Joseba Rebollo-Liceaga, Elena Mª Martínez-Navarro, Ramón González Manzano, Antonio Brugarolas, Manel Juan & Manuel Sureda. (2022) Relevance of Fc Gamma Receptor Polymorphisms in Cancer Therapy With Monoclonal Antibodies. Frontiers in Oncology 12.
Crossref
Tristan M. Sissung & William D. Figg. (2022) Pharmacogenomics Testing in Phase I Oncology Clinical Trials: Constructive Criticism Is Warranted. Cancers 14:5, pages 1131.
Crossref
Aleksandra Kusowska, Matylda Kubacz, Marta Krawczyk, Aleksander Slusarczyk, Magdalena Winiarska & Malgorzata Bobrowicz. (2022) Molecular Aspects of Resistance to Immunotherapies—Advances in Understanding and Management of Diffuse Large B-Cell Lymphoma. International Journal of Molecular Sciences 23:3, pages 1501.
Crossref
Laura Kiekens, Wouter Van Loocke, Sylvie Taveirne, Sigrid Wahlen, Eva Persyn, Els Van Ammel, Zenzi De Vos, Patrick Matthys, Filip Van Nieuwerburgh, Tom Taghon, Pieter Van Vlierberghe, Bart Vandekerckhove & Georges Leclercq. (2021) T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells. Frontiers in Immunology 12.
Crossref
Ashley Y. Choi, Miriam Manook, Danae Olaso, Brian Ezekian, Jaeberm Park, Kyle Freischlag, Annette Jackson, Stuart Knechtle & Jean Kwun. (2021) Emerging New Approaches in Desensitization: Targeted Therapies for HLA Sensitization. Frontiers in Immunology 12.
Crossref
Hilma J. van der Horst, Inger S. Nijhof, Tuna Mutis & Martine E. D. Chamuleau. (2020) Fc-Engineered Antibodies with Enhanced Fc-Effector Function for the Treatment of B-Cell Malignancies. Cancers 12:10, pages 3041.
Crossref
Stefania Crisci, Raffaele Di Francia, Sara Mele, Pasquale Vitale, Giuseppina Ronga, Rosaria De Filippi, Massimiliano Berretta, Paola Rossi & Antonio Pinto. (2019) Overview of Targeted Drugs for Mature B-Cell Non-hodgkin Lymphomas. Frontiers in Oncology 9.
Crossref
Grerk Sutamtewagul & Brian K. Link. (2019) Novel treatment approaches and future perspectives in follicular lymphoma. Therapeutic Advances in Hematology 10, pages 204062071882051.
Crossref
Martin Dalziel, Stephen A Beers, Mark S Cragg & Max Crispin. (2018) Through the barricades: overcoming the barriers to effective antibody-based cancer therapeutics. Glycobiology 28:9, pages 697-712.
Crossref
Aaron Galaznik, Rachel Huelin, Michael Stokes, Yelan Guo, Meredith Hoog, Tarun Bhagnani, Jill Bell & Yaping Shou. (2018) Systematic review of therapy used in relapsed or refractory diffuse large B-cell lymphoma and follicular lymphoma. Future Science OA 4:7, pages FSO322.
Crossref
Marie Viala, Marie Vinches, Marie Alexandre, Caroline Mollevi, Anna Durigova, Nadia Hayaoui, Krisztian Homicsko, Alice Cuenant, Céline Gongora, Luca Gianni & Diego Tosi. (2018) Strategies for clinical development of monoclonal antibodies beyond first-in-human trials: tested doses and rationale for dose selection. British Journal of Cancer 118:5, pages 679-697.
Crossref
L.A. Butler, C.S. Tam & J.F. Seymour. (2017) Dancing partners at the ball: Rational selection of next generation anti-CD20 antibodies for combination therapy of chronic lymphocytic leukemia in the novel agents era. Blood Reviews 31:5, pages 318-327.
Crossref
Maria Carmen Ochoa, Luna Minute, Inmaculada Rodriguez, Saray Garasa, Elisabeth Perez‐Ruiz, Susana Inogés, Ignacio Melero & Pedro Berraondo. (2017) Antibody‐dependent cell cytotoxicity: immunotherapy strategies enhancing effector NK cells. Immunology & Cell Biology 95:4, pages 347-355.
Crossref
Laurie H. Sehn. (2016) Novel agents in follicular lymphoma: choosing the best target. Hematology 2016:1, pages 284-292.
Crossref
Yaghoub Safdari, Vahideh Ahmadzadeh & Safar Farajnia. (2016) CD20-targeting in B-cell malignancies: novel prospects for antibodies and combination therapies. Investigational New Drugs 34:4, pages 497-512.
Crossref
Nitin Jain & Susan O'Brien. (2016) Targeted therapies for CLL: Practical issues with the changing treatment paradigm. Blood Reviews 30:3, pages 233-244.
Crossref
Tadeusz Robak, Jerzy Z. Blonski & Pawel Robak. (2016) Antibody therapy alone and in combination with targeted drugs in chronic lymphocytic leukemia. Seminars in Oncology 43:2, pages 280-290.
Crossref
Antonio Giovanni Solimando, Domenico Ribatti, Angelo Vacca & Hermann Einsele. (2016) Targeting B-cell non Hodgkin lymphoma: New and old tricks. Leukemia Research 42, pages 93-104.
Crossref
Carin I. M. Dahlberg, Dhifaf Sarhan, Michael Chrobok, Adil D. Duru & Evren Alici. (2015) Natural Killer Cell-Based Therapies Targeting Cancer: Possible Strategies to Gain and Sustain Anti-Tumor Activity. Frontiers in Immunology 6.
Crossref
Jon E. Arnason & Jennifer R. Brown. (2015) Targeted Therapy for Chronic Lymphocytic Leukemia: Current Status and Future Directions. Drugs 75:2, pages 143-155.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.