Advanced search
Publication Cover
Leukemia & Lymphoma Volume 56, 2015 - Issue 3
Submit an article Journal homepage
982
Views
19
CrossRef citations to date
0
Altmetric
Original Article: Clinical

Intrathecal methotrexate prophylaxis and central nervous system relapse in patients with diffuse large B-cell lymphoma following rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone

Naoto TomitaDepartment of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, JapanCorrespondence[email protected]
,
Hirotaka TakasakiDepartment of Medical Oncology, Kanagawa Cancer Center, Yokohama, Japan
,
Yasufumi IshiyamaDepartment of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
,
Kumiko KishimotoDepartment of Hematology, Yokohama City University Medical Center, Yokohama, Japan
,
Daisuke IshibashiDepartment of Hematology, Yokosuka City Hospital, Yokosuka, Japan
,
Satoshi KoyamaDepartment of Hematology, Shizuoka Red Cross Hospital, Shizuoka, Japan
,
Yoshimi IshiiDepartment of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
,
Hiroyuki TakahashiDepartment of Medical Oncology, Kanagawa Cancer Center, Yokohama, Japan
,
Ayumi NumataDepartment of Hematology, Yokohama City University Medical Center, Yokohama, Japan
,
Reina WatanabeDepartment of Medical Oncology, Kanagawa Cancer Center, Yokohama, Japan
,
Takayoshi TachibanaDepartment of Hematology, Yokohama City University Medical Center, Yokohama, Japan
,
Rika OhshimaDepartment of Hematology/Immunology, City Hospital, Fujisawa, Japan
,
Maki HagiharaDepartment of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
,
Chizuko HashimotoDepartment of Hematology/Oncology, Yamato Municipal Hospital, Yamato, Japan
,
Sachiya TakemuraDepartment of Hematology/Immunology, City Hospital, Fujisawa, Japan
,
Jun TaguchiDepartment of Hematology, Shizuoka Red Cross Hospital, Shizuoka, Japan
,
Katsumichi FujimakiDepartment of Hematology/Immunology, City Hospital, Fujisawa, Japan
,
Rika SakaiDepartment of Medical Oncology, Kanagawa Cancer Center, Yokohama, Japan
,
Shigeki MotomuraDepartment of Medical Oncology, Kanagawa Cancer Center, Yokohama, Japan
&
Yoshiaki IshigatsuboDepartment of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
 show all
Pages 725-729 | Received 22 Nov 2013, Accepted 01 Jun 2014, Published online: 06 Aug 2014

Citations (19)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Naoto Tomita, Masahiro Yokoyama, Wataru Yamamoto, Reina Watanabe, Yutaka Shimazu, Yasufumi Masaki, Saburo Tsunoda, Chizuko Hashimoto, Kayoko Murayama, Takahiro Yano, Rumiko Okamoto, Ako Kikuchi, Kazuo Tamura, Kazuya Sato, Kazutaka Sunami, Hirohiko Shibayama, Rishu Takimoto, Rika Ohshima, Hiromichi Takahashi, Yukiyoshi Moriuchi, Tomohiro Kinoshita, Masahide Yamamoto, Ayumi Numata, Hideaki Nakajima, Ikuo Miura & Kengo Takeuchi. (2018) The standard international prognostic index for predicting the risk of CNS involvement in DLBCL without specific prophylaxis. Leukemia & Lymphoma 59:1, pages 97-104.
Read now
Nicola Lehners, Isabelle Krämer, Mark-Alexander Schwarzbich, Anthony D. Ho & Mathias Witzens-Harig. (2016) Analysis of clinical characteristics and outcome of patients with previously untreated diffuse large B-cell lymphoma and renal involvement in the rituximab era. Leukemia & Lymphoma 57:11, pages 2619-2625.
Read now

Articles from other publishers (17)

Jillian Simard & Mark Roschewski. (2022) SOHO State of the Art Updates and Next Questions: Prophylaxis and Management of Secondary CNS Lymphoma. Clinical Lymphoma Myeloma and Leukemia 22:10, pages 709-717.
Crossref
Yu Fang, Ning Su, Shuyun Ma, Jun Cai, Liye Zhong, Wenyu Li, Huiqiang Huang, Zhiming Li, He Huang, Yi Xia, Panpan Liu, Linlang Guo, Zhihua Li, Yudan Wu, Xiaopeng Tian, Jinni Wang, Yuchen Zhang & Qingqing Cai. (2022) Optimization of high-dose methotrexate prophylaxis for central nervous system relapse in diffuse large B-cell lymphoma: a multicenter analysis. Annals of Hematology 101:3, pages 595-605.
Crossref
Shin Yeu Ong, Sanjay de Mel, Nicholas Francis Grigoropoulos, Yunxin Chen, Yan Chin Tan, Melinda Si Yun Tan, Lawrence Cheng Kiat Ng, Yuh Shan Lee, Colin Phipps, Yeow Tee Goh, Kar Ying Yong, Xin Liu, Wee Joo Chng, Soon Thye Lim & Chandramouli Nagarajan. (2021) High-dose methotrexate is effective for prevention of isolated CNS relapse in diffuse large B cell lymphoma. Blood Cancer Journal 11:8.
Crossref
S. Bernard, L. Hachon, J. F. Diasonama, C. Madaoui, L. Aguinaga, E. Miekoutima, H. Moatti, Emeline Perrial, I. Madelaine, P. Brice & Catherine Thieblemont. (2021) Ambulatory high-dose methotrexate administration as central nervous system prophylaxis in patients with aggressive lymphoma. Annals of Hematology 100:4, pages 979-986.
Crossref
John Xie, Albert Jang, Motohide Uemura, Shigeaki Nakazawa, Teresa Calimeri, Andres JM Ferreri, Shuang R. Chen, Janet L. Schmid, Theresa C. Brown, Francisco Socola, Hana Safah & Nakhle S. Saba. (2021) Systemic vs. intrathecal central nervous system prophylaxis in primary adrenal/renal diffuse large b-cell Lymphoma: A multi-institution retrospective analysis and systematic review. Leukemia Research Reports 16, pages 100263.
Crossref
Teresa Calimeri & Andrés J.M. Ferreri. (2020) Prevention of CNS relapse in diffuse large B‐cell lymphoma: common sense prevails where science fails. British Journal of Haematology 190:5, pages 645-647.
Crossref
Sara Alonso-Álvarez, Miguel Alcoceba, María García-Álvarez, Oscar Blanco, Marta Rodríguez, Mónica Baile, Juan Carlos Caballero, Julio Dávila, María Belén Vidriales, Carmen Esteban, Piedad Arias, Luis G. Díaz, Pilar Tamayo, María Dolores Caballero, Norma C. Gutiérrez, Marcos González & Alejandro Martín. (2020) Biological Features and Prognostic Impact of Bone Marrow Infiltration in Patients with Diffuse Large B-cell Lymphoma. Cancers 12:2, pages 474.
Crossref
Melissa J. Garwood, Eliza A. Hawkes, Leonid Churilov & Geoffrey Chong. (2019) Patient selection and tolerability of high-dose methotrexate as central nervous system prophylaxis in diffuse large B-cell lymphoma. Cancer Chemotherapy and Pharmacology 85:1, pages 133-140.
Crossref
Sinan DEMIRCIOGLU, Ufuk TELCI, Mahsun OZCELIK, Ali DOGAN & İrfan BAYRAM. (2019) Renal involvement in diffuse large B-cell lymphoma: A case report. Marmara Medical Journal 32:3, pages 144-146.
Crossref
Toby A. Eyre, Amy A. Kirkwood, Julia Wolf, Catherine Hildyard, Carolyn Mercer, Hannah Plaschkes, John Griffith, Paul Fields, Arief Gunawan, Rebecca Oliver, Stephen Booth, Nicolas Martinez‐Calle, Andrew McMillan, Mark Bishton, Christopher P. Fox, Graham P. Collins & Chris S. R. Hatton. (2019) Stand‐alone intrathecal central nervous system (CNS) prophylaxis provide unclear benefit in reducing CNS relapse risk in elderly DLBCL patients treated with R‐CHOP and is associated increased infection‐related toxicity. British Journal of Haematology 187:2, pages 185-194.
Crossref
A U Magomedova, A E Misyurina, J K Mangasarova, L G Gorenkova, O V Margolin, E A Fastova & S K Kravchenko. (2019) CNS involvement and the feasibility of intratecal chemotherapy administration in patients with a nodal form of diffuse large B-cell lymphoma not otherwise specified. Data of prospective study. Terapevticheskii arkhiv 91:7, pages 35-40.
Crossref
M. Hutchings, M. Ladetto, C. Buske, P. de Nully Brown, A.J.M. Ferreri, M. Pfreundschuh, N. Schmitz, A. Sureda Balari, G. van Imhoff & J. Walewski. (2018) ESMO Consensus Conference on malignant lymphoma: management of ‘ultra-high-risk’ patients. Annals of Oncology 29:8, pages 1687-1700.
Crossref
A.J.M. Ferreri. (2017) Secondary CNS lymphoma: the poisoned needle in the haystack. Annals of Oncology 28:10, pages 2335-2337.
Crossref
Kalliopi Pitarokoili, Felix Kohle, Jeremias Motte, Oluwaseun Fatoba, Xiomara Pedreiturria, Ralf Gold & Min-Suk Yoon. (2017) Anti-inflammatory and immunomodulatory potential of human immunoglobulin applied intrathecally in Lewis rat experimental autoimmune neuritis. Journal of Neuroimmunology 309, pages 58-67.
Crossref
Qing-Qing Cai, Li-Yang Hu, Qi-Rong Geng, Jie Chen, Zhen-Hai Lu, Hui-Lan Rao, Qing Liu, Wen-Qi Jiang, Hui-Qiang Huang, Tong-Yu Lin & Zhong-Jun Xia. (2016) New risk factors and new tendency for central nervous system relapse in patients with diffuse large B-cell lymphoma: a retrospective study. Chinese Journal of Cancer 35:1.
Crossref
Yusuke Kanemasa, Tatsu Shimoyama, Yuki Sasaki, Miho Tamura, Takeshi Sawada, Yasushi Omuro, Tsunekazu Hishima & Yoshiharu Maeda. (2016) Central nervous system relapse in patients with diffuse large B cell lymphoma: analysis of the risk factors and proposal of a new prognostic model. Annals of Hematology 95:10, pages 1661-1669.
Crossref
Abhimanyu Ghose. (2016) CNS Prophylaxis in Diffuse Large B cell Lymphoma. Journal of Cancer Prevention & Current Research 5:5.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.