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Leukemia & Lymphoma Volume 56, 2015 - Issue 11
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Original Articles: Clinical

Isolated MYC cytogenetic abnormalities in diffuse large B-cell lymphoma do not predict an adverse clinical outcome

Gabriel C. CaponettiDepartment of Pathology, Creighton University Medical Center, Omaha, NE, USA
,
Bhavana J. DaveHuman Genetics Laboratory, Munroe Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, NE, USA
,
Anamarija M. PerryDepartment of Pathology, University of Manitoba, Winnipeg, Manitoba, Canada
,
Lynette M. SmithDepartment of Biostatistics, University of Nebraska Medical Center, Omaha, NE, USA
,
Smrati JainHuman Genetics Laboratory, Munroe Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, NE, USA
,
Paul N. MeyerSouthern Arizona Veterans Administration Health Care, Tucson, AZ
,
Martin BastInternal Medicine, University of Nebraska Medical Center, Omaha, NE, USA
,
Philip J. BiermanInternal Medicine, University of Nebraska Medical Center, Omaha, NE, USA
,
Robert G. BociekInternal Medicine, University of Nebraska Medical Center, Omaha, NE, USA
,
Julie M. VoseInternal Medicine, University of Nebraska Medical Center, Omaha, NE, USA
,
James O. ArmitageInternal Medicine, University of Nebraska Medical Center, Omaha, NE, USA
,
Patricia AounDepartment of Pathology, City of Hope National Medical Center, Duarte, CA, USA
,
Kai FuPathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA
,
Timothy C. GreinerPathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA
,
Wing C. ChanDepartment of Pathology, City of Hope National Medical Center, Duarte, CA, USA
,
Warren G. SangerHuman Genetics Laboratory, Munroe Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, NE, USA
&
Dennis D. WeisenburgerDepartment of Pathology, City of Hope National Medical Center, Duarte, CA, USACorrespondence[email protected]
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Pages 3082-3089 | Received 14 Nov 2014, Accepted 21 Mar 2015, Published online: 12 May 2015

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Hiromichi Takahashi, Katsuhiro Miura, Masaru Nakagawa, Masahiko Sugitani, Yusuke Amano, Daisuke Kurita, Masashi Sakagami, Shimon Ohtake, Yoshihito Uchino, Hitomi Kodaira, Noriyoshi Iriyama, Sumiko Kobayashi, Atsuko Hojo, Yujin Kobayashi, Yukio Hirabayashi, Machiko Kusuda, Yoshihiro Hatta, Tomohiro Nakayama & Masami Takei. (2016) Negative impact of concurrent overexpression of MYC and BCL2 in patients with advanced diffuse large B-cell lymphoma treated with dose-intensified immunochemotherapy. Leukemia & Lymphoma 57:12, pages 2784-2790.
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Katsuhiro Miura, Hiromichi Takahashi, Masaru Nakagawa, Asami Izu, Masahiko Sugitani, Daisuke Kurita, Masashi Sakagami, Shimon Ohtake, Yoshihito Uchino, Atsuko Hojo, Hitomi Kodaira, Mai Yagi, Yujin Kobayashi, Noriyoshi Iriyama, Sumiko Kobayashi, Satomi Kiso, Yukio Hirabayashi, Yoshihiro Hatta & Masami Takei. (2016) Clinical significance of co-expression of MYC and BCL2 protein in aggressive B-cell lymphomas treated with a second line immunochemotherapy. Leukemia & Lymphoma 57:6, pages 1335-1341.
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Marie José Kersten & Jeroen E. J. Guikema. (2015) MYC in diffuse large B-cell lymphoma: always the bad guy?. Leukemia & Lymphoma 56:11, pages 3003-3004.
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Articles from other publishers (10)

Dongfeng Zeng, Aakash Desai, Fangfang Yan, Tiejun Gong, Haige Ye, Makhdum Ahmed, Krystle Nomie, Jorge Romaguera, Richard Champlin, Shaoying Li & Michael Wang. (2019) Challenges and Opportunities for High-grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangement (Double-hit Lymphoma). American Journal of Clinical Oncology 42:3, pages 304-316.
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Erika M. Moore, Nidhi Aggarwal, Urvashi Surti & Steven H. Swerdlow. (2017) Further Exploration of the Complexities of Large B-Cell Lymphomas With MYC Abnormalities and the Importance of a Blastoid Morphology. American Journal of Surgical Pathology 41:9, pages 1155-1166.
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Pierre Sesques & Nathalie A. Johnson. (2017) Approach to the diagnosis and treatment of high-grade B-cell lymphomas with MYC and BCL2 and/or BCL6 rearrangements. Blood 129:3, pages 280-288.
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Alex F. HerreraMatthew MeiLawrence LowHaesook T. KimGabriel K. GriffinJoo Y. SongReid W. MerrymanVictoria BedellChristine PakHeather SunTanya ParisTracey StillerJennifer R. BrownLihua E. BuddeWing C. ChanRobert ChenMatthew S. DavidsArnold S. FreedmanDavid C. FisherEric D. JacobsenCaron A. JacobsonAnn S. LaCasceJoyce Murata-CollinsAuayporn P. NademaneeJoycelynne M. PalmerGerman A. PihanRaju PillaiLeslie PopplewellTanya SiddiqiAliyah R. SohaniJasmine ZainSteven T. RosenLarry W. KwakDavid M. WeinstockStephen J. FormanDennis D. WeisenburgerYoung KimScott J. RodigAmrita KrishnanPhilippe Armand. (2017) Relapsed or Refractory Double-Expressor and Double-Hit Lymphomas Have Inferior Progression-Free Survival After Autologous Stem-Cell Transplantation. Journal of Clinical Oncology 35:1, pages 24-31.
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Joo Y. Song & Dennis D. Weisenburger. 2017. Management of Lymphomas: A Case-Based Approach. Management of Lymphomas: A Case-Based Approach 33 44 .
Bertrand Coiffier & Clémentine Sarkozy. (2016) Diffuse large B-cell lymphoma: R-CHOP failure—what to do?. Hematology 2016:1, pages 366-378.
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Daniel J. Landsburg, Marissa K. Falkiewicz, Adam M. Petrich, Benjamin A. Chu, Amir Behdad, Shaoying Li, L. Jeffrey Medeiros, Ryan D. Cassaday, Nishitha M. Reddy, Martin A. Bast, Julie M. Vose, Kimberly R. Kruczek, Scott E. Smith, Priyank Patel, Francisco Hernandez-Ilizaliturri, Reem Karmali, Saurabh Rajguru, David T. Yang, Joseph J. Maly, Kristie A. Blum, Weiqiang Zhao, Charles Vanslambrouck & Chadi Nabhan. (2016) Sole rearrangement but not amplification of MYC is associated with a poor prognosis in patients with diffuse large B cell lymphoma and B cell lymphoma unclassifiable . British Journal of Haematology 175:4, pages 631-640.
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Penelope Korkolopoulou, Theodoros Vassilakopoulos, Vassilios Milionis & Maria Ioannou. (2016) Recent Advances in Aggressive Large B-cell Lymphomas: A Comprehensive Review. Advances in Anatomic Pathology 23:4, pages 202-243.
Crossref
Daniel J. Landsburg. (2016) Management of Patients with MYC-Altered Lymphomas. Current Hematologic Malignancy Reports 11:3, pages 208-217.
Crossref
J. Han van Krieken. (2015) New developments in the pathology of malignant lymphoma: a review of literature published from January 2015 to April 2015. Journal of Hematopathology 8:2, pages 71-79.
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