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Original Article

Interleukin-6 in Multiple Myeloma: Correlation with Disease Activity and Ki-67 Proliferation Index

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Pages 265-271 | Received 31 Dec 1992, Published online: 01 Jul 2009

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Richard L. Soutar, John M. Dillon, Domenyk Brown & Stuart H. Ralston. (1996) Cytokine Expression in Multiple Myeloma and Monoclonal Gammopathy: Analysis by Reverse Transcription/Polymerase Chain Reaction and Quantitative PCR. Leukemia & Lymphoma 24:1-2, pages 111-120.
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J. T. Whicher & R. E. Banks. (1995) Cytokines as tumour markers. Scandinavian Journal of Clinical and Laboratory Investigation 55:sup221, pages 122-144.
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Michael G. Alexandrakis, Parascevi Roussou, Constantina A. Pappa, Ippokratis Messaritakis, Athina Xekalou, Nektaria Goulidaki, Anna Boula & George Tsirakis. (2013) Relationship between Circulating BAFF Serum Levels with Proliferating Markers in Patients with Multiple Myeloma. BioMed Research International 2013, pages 1-6.
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Zeinab H. El-badawi, Amal N.E. Ahmed, Medhat M. Ali & Abd-El-Rahman H. Khalifa. (2012) Correlation of CD74 expression with the Ki-67-labeling index and CD138 in multiple myeloma. Egyptian Journal of Pathology 32:2, pages 198-203.
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G. Tsirakis, C.A. Pappa, M. Spanoudakis, D. Chochlakis, A. Alegakis, F.E. Psarakis, M. Stratinaki, E.N. Stathopoulos & M.G. Alexandrakis. (2012) Clinical significance of sCD105 in angiogenesis and disease activity in multiple myeloma. European Journal of Internal Medicine 23:4, pages 368-373.
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Flavia Regina P. Barbosa, Leonardo Vieira Neto, Giovanna Aparecida B. Lima, Luiz Eduardo Wildemberg, Rodrigo Portugal & Monica R. Gadelha. (2009) Hematologic neoplasias and acromegaly. Pituitary 14:4, pages 377-381.
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Wiltrud Lederle, Sofia Depner, Sabine Schnur, Eva Obermueller, Nicola Catone, Alexandra Just, Norbert E. Fusenig & Margareta M. Mueller. (2011) IL-6 promotes malignant growth of skin SCCs by regulating a network of autocrine and paracrine cytokines. International Journal of Cancer 128:12, pages 2803-2814.
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Miguel Lemaire, Sarah Deleu, Elke De Bruyne, Els Van Valckenborgh, Eline Menu & Karin Vanderkerken. 2011. 19 42 .
Michael G. Alexandrakis, Freda H. Passam, Despina S. Kyriakou, Konstantina Dambaki, Maria Niniraki & Efstathios Stathopoulos. (2004) Ki-67 Proliferation Index. American Journal of Clinical Oncology 27:1, pages 8-13.
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M.G. Alexandrakis, F.H. Passam, C.A. Pappa, C. Dambaki, G. Sfakiotaki, A.K. Alegakis, D.S. Kyriakou & E. Stathopoulos. (2016) Expression of Proliferating Cell Nuclear Antigen (PCNA) in Multiple Myeloma: Its Relationship to Bone Marrow Microvessel Density and other Factors of Disease Activity. International Journal of Immunopathology and Pharmacology 17:1, pages 49-56.
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Nie-Lin GeStuart Rudikoff. (2000) Insulin-like growth factor I is a dual effector of multiple myeloma cell growth. Blood 96:8, pages 2856-2861.
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Nie-Lin GeStuart Rudikoff. (2000) Insulin-like growth factor I is a dual effector of multiple myeloma cell growth. Blood 96:8, pages 2856-2861.
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Schaar, Kaiser, Snijder, Ong, Hermans, Franck & Kluin‐Nelemans. (2008) Serum interleukin‐6 has no discriminatory role in paraproteinaemia nor a prognostic role in multiple myeloma. British Journal of Haematology 107:1, pages 132-138.
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Lidia Usnarska-Zubkiewicz. (1999) Cytomorphology and proliferating cell nuclear antigen in myeloma plasma cells correlate with serum Il-6 and sIl-6R concentrations in multiple myeloma. European Journal of Internal Medicine 10:2, pages 101-105.
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Agnieszka Wierzbowska, Halina Urbańska‐Ryś & Tadeusz Robak. (2005) Circulating IL‐6‐type cytokines and sIL‐6R in patients with multiple myeloma. British Journal of Haematology 105:2, pages 412-419.
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Michael HallekP. Leif BergsagelKenneth C. Anderson. (1998) Multiple Myeloma: Increasing Evidence for a Multistep Transformation Process. Blood 91:1, pages 3-21.
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Michael HallekP. Leif BergsagelKenneth C. Anderson. (1998) Multiple Myeloma: Increasing Evidence for a Multistep Transformation Process. Blood 91:1, pages 3-21.
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Andreas Villunger, Alexander Egle, Marion Kos, Anton Hittmair, Karl Maly & Richard Greil. (1996) Constituents of autocrine IL-6 loops in myeloma cell lines and their targeting for suppression of neoplastic growth by antibody strategies. International Journal of Cancer 65:4, pages 498-505.
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Martin Lotz. 1996. Cytokines: Interleukins and Their Receptors. Cytokines: Interleukins and Their Receptors 209 233 .

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