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Leukemia & Lymphoma Volume 22, 1996 - Issue 1-2
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Original Article

Morphologic Evidence of Apoptosis in Childhood Acute Myeloblastic Leukemia Treated with High-Dose Methylprednisolone

Gönül Hiçsönmez Department of Pediatric Hematology Faculty of Medicine, Hacettepe University, Ankara, Turkey
,
Esra Erdemli Department of Histology and Embryology Faculty of Medicine, Ankara University, Ankara, Turkey
,
Meral Tekelioglu Department of Histology and Embryology Faculty of Medicine, Ankara University, Ankara, Turkey
,
A. Murat Tuncer Department of Pediatric Hematology Faculty of Medicine, Hacettepe University, Ankara, Turkey
,
Namik özbek Department of Pediatric Hematology Faculty of Medicine, Hacettepe University, Ankara, Turkey
,
Mualla çtin Department of Pediatric Hematology Faculty of Medicine, Hacettepe University, Ankara, Turkey
&
Thomas G. Cotter Department of Biology, Saint Patrick's College, Maynooth, Ireland
 show all
Pages 91-96 | Received 05 Oct 1995, Published online: 01 Jul 2009

Citations (21)

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Read on this site (4)

Burçin Tezcanli Kaymaz, Nur Selvi, Güray Saydam, Fahri Şahin & Buket Kosova. (2012) Methylprednisolone induces apoptosis by interacting with the JAK/STAT pathway in HL-60 and K-562 leukemic cells. Hematology 17:2, pages 93-99.
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Gönül Hiçsönmez, Mualla Çetin, Idil Yenicesu, Lale Olcay, Ahmet Koç, Dilek Aktas, Ergül Tunçbilek & Murat Tuncer. (2001) Evaluation of Children with Myelodysplastic Syndrome: Importance of Extramedullary Disease as a Presenting Symptom. Leukemia & Lymphoma 42:4, pages 665-674.
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GÖNÜL Hiçsönmez, Murat Tuncer, Hayri B. Toksoy, Idil Yenicesu & Mualla Çetin. (1999) Differentiation of Leukemic Cells Induced by Short-Course High-Dose Methylprednisolone in Children with Different Subtypes of Acute Myeloblastic Leukemia. Leukemia & Lymphoma 33:5-6, pages 573-580.
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Gönül Hiçsönmez, Mualla Çletin, Bahattin Tunç, A. Murat Tuncer, Fatma Gümrük & İdil Yenicesu. (1998) Dramatic Resolution of Pleural Effusion in Children with Chronic Myelomonocytic Leukemia Following Short-course High-dose Methylprednisolone. Leukemia & Lymphoma 29:5-6, pages 617-623.
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Articles from other publishers (17)

Şinasi Özsoylu & Sevgi Yetgin. (2007) About Megadose Methylprednisolone. Journal of Pediatric Hematology/Oncology 29:12, pages 864-865.
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Sevgi Yetgin & Şinasi Özsoylu. (2007) Comparison of Megadose Methylprednisolone Versus Conventional Dose Prednisolone in Hematologic Disorders. Journal of Pediatric Hematology/Oncology 29:4, pages 253-259.
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Gönül Hiçsönmez. (2006) The effect of steroid on myeloid leukemic cells: The potential of short-course high-dose methylprednisolone treatment in inducing differentiation, apoptosis and in stimulating myelopoiesis. Leukemia Research 30:1, pages 60-68.
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Gönül Hiçsönmez, Mualla Çetin, A.Murat Tuncer, İdil Yenicesu, Deniz Aslan, Emel Özyürek & Selma Ünal. (2004) Children with acute myeloblastic leukemia presenting with extramedullary infiltration: the effects of high-dose steroid treatment. Leukemia Research 28:1, pages 25-34.
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Bahattin Tunç, Ahmet F Öner & Gönül Hiçsönmez. (2003) The effect of short-course high-dose methylprednisolone on peripheral blood lymphocyte subsets in children with acute leukemia during remission induction treatment. Leukemia Research 27:1, pages 19-21.
Crossref
Safak Yuksel, Guray Saydam, Ruchan Uslu, Ulus Ali Sanli, Ender Terzioglu, Filiz Buyukececi & Serdar Bedii Omay. (2002) Arsenic trioxide and methylprednisolone use different signal transduction pathways in leukemic differentiation. Leukemia Research 26:4, pages 391-398.
Crossref
Yoko Shimohakamada, Kenji Shinohara & Naofumi Fukuda. (2018) Remission of Acute Myeloblastic Leukemia After Severe Pneumonia Treated With High-Dose Methylprednisolone. International Journal of Hematology 74:2, pages 173-177.
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Øystein Bruserud, Bjørn Tore Gjertsen & Tien-sheng Huang. (2000) Induction of Differentiation and Apoptosis— A Possible Strategy in the Treatment of Adult Acute Myelogenous Leukemia. The Oncologist 5:6, pages 454-462.
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H.H. Aydin, N. Selvi, G. Saydam, M. Tobu, S. Uzunoglu, R. Uslu, F. Buyukkececi & S.B. Omay. (2000) Up-regulation of serine/threonine protein phosphatase type 2A regulatory subunits during methylprednisolone-induced differentiation of leukaemic HL-60 cells. Clinical & Laboratory Haematology 22:5, pages 271-274.
Crossref
Øystein Bruserud & Bjørn Tore Gjertsen. (2009) New Strategies for the Treatment of Acute Myelogenous Leukemia: Differentiation Induction—Present Use and Future Possibilities. STEM CELLS 18:3, pages 157-165.
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Selim Uzunoglu, Ruchan Uslu, Mahmut Tobu, Guray Saydam, Ender Terzioglu, Filiz Buyukkececi & Serdar Bedii Omay. (1999) Augmentation of methylprednisolone-induced differentiation of myeloid leukemia cells by serine/threonine protein phosphatase inhibitors. Leukemia Research 23:5, pages 507-512.
Crossref
Nam?k �zbek, Esra Erdemli, G�n�l Hi�s�nmez, Hamza Okur & Meral Tekelio?lu. (1999) Effects of methylprednisolone on human myeloid leukemic cells in vitro. American Journal of Hematology 60:4, pages 255-259.
Crossref
Allen F. Pyesmany, Lynne M. Ball, Margaret Yhap, M. Henry, Krista Laybolt, D. Christie Riddell & Dick van Velzen. 1999. Drug Resistance in Leukemia and Lymphoma III. Drug Resistance in Leukemia and Lymphoma III 305 312 .
Lynne M. Ball, Allen F. Pyesmany, Margaret Yhap, Christopher L. Lannon, M. Henry, Krista Laybolt, D. Christie Riddell & Dick van Velzen. 1999. Drug Resistance in Leukemia and Lymphoma III. Drug Resistance in Leukemia and Lymphoma III 297 303 .
Lynne M. Ball, Christopher L. Lannon, Margaret Yhap, Allen F. Pyesmany, M. Henry, Krista Laybolt, D. Christie Riddell & Dick van Velzen. 1999. Drug Resistance in Leukemia and Lymphoma III. Drug Resistance in Leukemia and Lymphoma III 289 296 .
Allen F. Pyesmany, Lynne M. Ball, Margaret Yhap, M. Henry, Krista Laybolt, D. Christie Riddell & Dick van Velzen. 1999. Drug Resistance in Leukemia and Lymphoma III. Drug Resistance in Leukemia and Lymphoma III 281 287 .
G. HiçsÖnmez, F. Gümrük, P. V. Zamani, M. A. Tuncer, S. Yetgin, A. Gürgey, L. Atahan & S. Özsoylu. (2009) High‐dose methylprednisolone for children with acute lymphoblastic leukemia and unfavorable presenting features. European Journal of Haematology 58:1, pages 26-31.
Crossref

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