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Original Article

Expression of Glycosyl-Phosphatidylinositol-Linked Glycoproteins in Blood Cells from Paroxysmal Nocturnal Haemoglobinuria Patients a Flow Cytometry Study using CD55, CD58 and CD59 Monoclonal Antibodies

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Pages 143-151 | Received 15 May 1995, Published online: 01 Jul 2009

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Margarida Lima. (2020) Laboratory studies for paroxysmal nocturnal hemoglobinuria, with emphasis on flow cytometry. Practical Laboratory Medicine 20, pages e00158.
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Johanna Blaha, Klaus Schwarz, Claudia Fischer, Peter Schauwecker, Britta Höchsmann, Hubert Schrezenmeier & Markus Anliker. (2018) The Monoclonal Anti-CD157 Antibody Clone SY11B5, Used for High Sensitivity Detection of PNH Clones on WBCs, Fails to Detect a Common Polymorphic Variant Encoded by BST-1 . Cytometry Part B: Clinical Cytometry 94:4, pages 652-659.
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Stephen J. Richards. 2012. Laboratory Hematology Practice. Laboratory Hematology Practice 399 405 .
Hubert Schrezenmeier, Peter Bettelheim, Jens Panse, Jörg Schubert, Britta Höchsmann, Alexander Röth & Thomas Nebe. (2011) Empfehlungen zur Diagnostik der Paroxysmalen nächtlichen Hämoglobinurie: deutsch – österreichischer Konsensus/Recommendations for the diagnosis of paroxysmal nocturnal hemoglobinuria: a German-Austrian consensus. LaboratoriumsMedizin 35:6, pages 315-327.
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Michael J. Borowitz, Fiona E. Craig, Joseph A. DiGiuseppe, Andrea J. Illingworth, Wendell Rosse, D. Robert Sutherland, Carl T. Wittwer & Stephen J. Richards. (2010) Guidelines for the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria and related disorders by flow cytometry. Cytometry Part B: Clinical Cytometry 78B:4, pages 211-230.
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P. Moncharmont, F. Barraco, J. Bernaud, A. Raffin, M. Michallet & D. Rigal. (2009) Suivi biologique des patients atteints d?h?moglobinurie paroxystique nocturne et trait?s par eculizumab. Immuno-analyse & Biologie Sp?cialis?e 24:2, pages 86-91.
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Jrg Schubert, Peter Hillmen, Alexander Rth, Neal S. Young, Modupe O. Elebute, Jeffrey Szer, Giacomo Gianfaldoni, Grard Soci, Paul Browne, Robert Geller, Russell P. Rother & Petra Muus. (2008) Eculizumab, a terminal complement inhibitor, improves anaemia in patients with paroxysmal nocturnal haemoglobinuria. British Journal of Haematology 142:2, pages 263-272.
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Stephen J. Richards & David Barnett. (2007) The Role of Flow Cytometry in the Diagnosis of Paroxysmal Nocturnal Hemoglobinuria in the Clinical Laboratory. Clinics in Laboratory Medicine 27:3, pages 577-590.
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Stephen J. Richards, Anita Hill & Peter Hillmen. (2007) Recent advances in the diagnosis, monitoring, and management of patients with paroxysmal nocturnal hemoglobinuria. Cytometry Part B: Clinical Cytometry 72B:5, pages 291-298.
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Jean-Pierre Louboutin, Jean-Marc Navenot, Karl Rouger & Dominique Blanchard. (2003) S-protein is expressed in necrotic fibers in Duchenne muscular dystrophy and polymyositis. Muscle & Nerve 27:5, pages 575-581.
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T. Nebe, J. Schubert, K. Gutensohn & H. Schrezenmeier. (2003) Flow Cytometric Analysis of GPI-deficient Cells for the Diagnosis of Paroxysmal Nocturnal Hemoglobinuria (PNH)/Durchflußzytometrische Analyse GPI-defizienter Zellen zur Diagnose der paroxysmalen nächtlichen Hämoglobinurie (PNH). LaboratoriumsMedizin 27:7/8, pages 257-265.
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Rosa Núñez-López, Luis Escribano, Gerit-Holger Schernthaner, Aránzazu Prados, Ramón Rodríguez-González, Beatriz Díaz-Agustín, Antonio López, Alexander Hauswirth, Peter Valent, Julia Almeida, Pilar Bravo & Alberto Orfao. (2003) Overexpression of complement receptors and related antigens on the surface of bone marrow mast cells in patients with systemic mastocytosis. British Journal of Haematology 120:2, pages 257-265.
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M. Nelson. 2003. Advanced Flow Cytometry: Applications in Biological Research. Advanced Flow Cytometry: Applications in Biological Research 19 25 .
Stephen J. Richards & Peter Hillmen. (2002) Immunophenotypic Analysis of PNH Cells. Current Protocols in Cytometry 20:1.
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Stephen J. Richards & Peter Hillmen. (2001) Advances in the laboratory diagnosis of paroxysmal nocturnal hemoglobinuria. Clinical and Applied Immunology Reviews 1:6, pages 315-330.
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U. Oelschlaegel, I. Besson, C. Arnoulet, D. Sainty, R. Nowak, R. Naumann, Y. Bux & G. Ehninger. (2001) A standardized flow cytometric method for screening paroxysmal nocturnal haemoglobinuria (PNH) measuring CD55 and CD59 expression on erythrocytes and granulocytes. Clinical & Laboratory Haematology 23:2, pages 81-90.
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Stephen J. RichardsGareth J. MorganPeter Hillmen. (2000) Immunophenotypic analysis of B cells in PNH: insights into the generation of circulating naive and memory B cells. Blood 96:10, pages 3522-3528.
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Stephen J. Richards, Andrew C. Rawstron & Peter Hillmen. (2000) Application of flow cytometry to the diagnosis of paroxysmal nocturnal hemoglobinuria. Cytometry 42:4, pages 223-233.
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Helmut Schenkel-BrunnerHelmut Schenkel-Brunner. 2000. Human Blood Groups. Human Blood Groups 30 53 .
Stephen J. RichardsGareth J. MorganPeter Hillmen. (1999) Analysis of T Cells in Paroxysmal Nocturnal Hemoglobinuria Provides Direct Evidence That Thymic T-Cell Production Declines With Age. Blood 94:8, pages 2790-2799.
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H. Min, SD. Thirumala & M.E Reid. (1999) Laboratory diagnosis of paroxysmal nocturnal hemoglobinura: a review. Immunohematology 15:4, pages 144-149.
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Stephen. J. RichardsDerek. R. NorfolkDavid M. SwirskyPeter Hillmen. (1998) Lymphocyte Subset Analysis and Glycosylphosphatidylinositol Phenotype in Patients With Paroxysmal Nocturnal Hemoglobinuria. Blood 92:5, pages 1799-1806.
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J. M. Navenot, J. Y. Muller & D. Blanchard. (2002) Investigation of the survival of paroxysmal nocturnal hemoglobinuria red cells through the immunophenotyping of reticulocytes. Transfusion 38:4, pages 337-342.
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J.‐M. Navenot, J.‐Y. Mullet & D. Blanchard. (2003) Expression of blood group i antigen and fetal hemoglobin in paroxysmal nocturnal hemoglobinuria. Transfusion 37:3, pages 291-297.
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D. Blanchard, Y. Petit-Le Roux, C. Willem & M.J. Loirat. (1997) Flow cytometry and immunoblotting analysis of monoclonal antibodies directed to CD-related antigens. Transfusion Clinique et Biologique 4:1, pages 153-156.
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D. Blanchard, J.M. Navenot, Y. Petit-Le Roux, C. Willem & M.J. Loirat. (1997) Flow cytometry and immunoblotting analysis of monoclonal antibodies directed to complement regulatory proteins. Transfusion Clinique et Biologique 4:1, pages 131-134.
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Jean-Marc Navenot, Marcello Villanova, Brigitte Lucas-H�ron, Alessandro Malandrini, Dominique Blanchard & Jean-Pierre Louboutin. (1997) Expression of CD59, a regulator of the membrane attack complex of complement, on human skeletal muscle fibers. Muscle & Nerve 20:1, pages 92-96.
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