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Leukemia & Lymphoma Volume 25, 1997 - Issue 1-2
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Original Article

Recent Progress On the Role of Axl, A Receptor Tyrosine Kinase, in Malignant Transformation of Myeloid Leukemias

Andreas Neubauer Virchow Klinikum, Medizinische Fakultät der Humboldt Universität zu Berlin, Abteilung für Innere Medizin-Hämatologie, Augustenburger Platz 1, 13353Berlin
,
Andreas Burchert Virchow Klinikum, Medizinische Fakultät der Humboldt Universität zu Berlin, Abteilung für Innere Medizin-Hämatologie, Augustenburger Platz 1, 13353Berlin
,
Carolyn Maiwald Virchow Klinikum, Medizinische Fakultät der Humboldt Universität zu Berlin, Abteilung für Innere Medizin-Hämatologie, Augustenburger Platz 1, 13353Berlin
,
Hans-JÜRgen Gruss Abteilung Angewandte Molekularbiologie, Robert Rössle Klinik, Virchow-Klinikum, Berlin-Buch
,
Stefan Serke Virchow Klinikum, Medizinische Fakultät der Humboldt Universität zu Berlin, Abteilung für Innere Medizin-Hämatologie, Augustenburger Platz 1, 13353Berlin
,
Dieter Huhn Virchow Klinikum, Medizinische Fakultät der Humboldt Universität zu Berlin, Abteilung für Innere Medizin-Hämatologie, Augustenburger Platz 1, 13353Berlin
,
Burghardt Wittig Abteilung Molekularbiologie und Bioinformatik, Freie Universität Berlin, Germany
&
Edison Liu Lineberger Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA
 show all
Pages 91-96 | Accepted 28 Apr 1996, Published online: 01 Jul 2009

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Melanie Janning, Isabel Ben-Batalla & Sonja Loges. (2015) Axl inhibition: a potential road to a novel acute myeloid leukemia therapy?. Expert Review of Hematology 8:2, pages 135-138.
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Articles from other publishers (23)

Pei-Ling Hsu, Jonathan Jou & Shaw-Jenq Tsai. (2019) TYRO3: A potential therapeutic target in cancer. Experimental Biology and Medicine 244:2, pages 83-99.
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Eun-Hee Lee, Eun-Mi Kim, Kon-Young Ji, A-Reum Park, Ha-Rim Choi, Hwa-Youn Lee, Su-Man Kim, Byung Yeoup Chung, Chul-Hong Park, Hyo Jin Choi, Young-Hyeh Ko, Hyoung-Woo Bai & Hyung-Sik Kang. (2017) Axl acts as a tumor suppressor by regulating LIGHT expression in T lymphoma. Oncotarget 8:13, pages 20645-20655.
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C-W Chien, P-C Hou, H-C Wu, Y-L Chang, S-C Lin, S-C Lin, B-W Lin, J-C Lee, Y-J Chang, H S Sun & S-J Tsai. (2016) Targeting TYRO3 inhibits epithelial–mesenchymal transition and increases drug sensitivity in colon cancer. Oncogene 35:45, pages 5872-5881.
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Mattia Bellan, Mario Pirisi & Pier Sainaghi. (2016) The Gas6/TAM System and Multiple Sclerosis. International Journal of Molecular Sciences 17:11, pages 1807.
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Tianfu Wu, Huihua Ding, Jie Han, Cristina Arriens, Chungwen Wei, Weilu Han, Claudia Pedroza, Shan Jiang, Jennifer Anolik, Michelle Petri, Ignacio Sanz, Ramesh Saxena & Chandra Mohan. (2016) Antibody-Array-Based Proteomic Screening of Serum Markers in Systemic Lupus Erythematosus: A Discovery Study. Journal of Proteome Research 15:7, pages 2102-2114.
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Juliano D. Paccez, Kristal Duncan, Akhona Vava, Ricardo G. Correa, Towia A. Libermann, M. Iqbal Parker & Luiz F. Zerbini. (2015) Inactivation of GSK3β and activation of NF-κB pathway via Axl represents an important mediator of tumorigenesis in esophageal squamous cell carcinoma. Molecular Biology of the Cell 26:5, pages 821-831.
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Gabriela Silva, Bruno A. Cardoso, Hélio Belo & António Medina Almeida. (2013) Vorinostat Induces Apoptosis and Differentiation in Myeloid Malignancies: Genetic and Molecular Mechanisms. PLoS ONE 8:1, pages e53766.
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S. Bavcar & D. J. Argyle. (2012) Receptor tyrosine kinase inhibitors: molecularly targeted drugs for veterinary cancer therapy. Veterinary and Comparative Oncology 10:3, pages 163-173.
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Thomas Schmidt, Isabel Ben-Batalla, Alexander Schultze & Sonja Loges. (2011) Macrophage–tumor crosstalk: role of TAMR tyrosine kinase receptors and of their ligands. Cellular and Molecular Life Sciences 69:9, pages 1391-1414.
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Maeva Dufies, Arnaud Jacquel, Nathalie Belhacene, Guillaume Robert, Thomas Cluzeau, Fréderic Luciano, Jill Patrice Cassuto, Sophie Raynaud & Patrick Auberger. (2011) Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells. Oncotarget 2:11, pages 874-885.
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Cheryl A. London. (2009) Tyrosine Kinase Inhibitors in Veterinary Medicine. Topics in Companion Animal Medicine 24:3, pages 106-112.
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Cheryl A. London. (2007) The Role of Small Molecule Inhibitors for Veterinary Patients. Veterinary Clinics of North America: Small Animal Practice 37:6, pages 1121-1136.
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Sassan Hafizi, Anna Gustafsson, Jonas Stenhoff & Björn Dahlbäck. (2005) The Ran binding protein RanBPM interacts with Axl and Sky receptor tyrosine kinases. The International Journal of Biochemistry & Cell Biology 37:11, pages 2344-2356.
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Z. Ju, M. Kapoor, K. Newton, K. Cheon, A. Ramaswamy, R. Lotan, L. C. Strong & J. S. Koo. (2005) Global detection of molecular changes reveals concurrent alteration of several biological pathways in nonsmall cell lung cancer cells. Molecular Genetics and Genomics 274:2, pages 141-154.
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Paul W. FISHERMichael BRIGHAM-BURKESheng-Jiun WUJinquan LUOJill CARTONKim STAQUETWei GAOSheila JACKSONDeidra BETHEACailin CHENBing HUJill GILES-KOMARJing YANG. (2005) A novel site contributing to growth-arrest-specific gene 6 binding to its receptors as revealed by a human monoclonal antibody. Biochemical Journal 387:3, pages 727-735.
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Karl D. Mack, Melissa Von Goetz, Monica Lin, Marina Venegas, Jerry Barnhart, Yan Lu, Betty Lamar, Robert Stull, Christopher Silvin, Pamela Owings, Fong-Yih Bih & Arie Abo. (2005) Functional identification of kinases essential for T-cell activation through a genetic suppression screen. Immunology Letters 96:1, pages 129-145.
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C. London. (2004) Kinase inhibitors in cancer therapy. Veterinary and Comparative Oncology 2:4, pages 177-193.
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Greg Lemke & Qingxian Lu. (2003) Macrophage regulation by Tyro 3 family receptors. Current Opinion in Immunology 15:1, pages 31-36.
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Sassan Hafizi, Filiz Alindri, Roger Karlsson & Björn Dahlbäck. (2002) Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology to tensin. Biochemical and Biophysical Research Communications 299:5, pages 793-800.
Crossref
Rajeev Gupta, Caroline L. Knight & Barbara J. Bain. (2002) Receptor tyrosine kinase mutations in myeloid neoplasms. British Journal of Haematology 117:3, pages 489-508.
Crossref
Qingxian LuGreg Lemke. (2001) Homeostatic Regulation of the Immune System by Receptor Tyrosine Kinases of the Tyro 3 Family. Science 293:5528, pages 306-311.
Crossref
A Wimmel, D Glitz, A Kraus, J Roeder & M Schuermann. (2001) Axl receptor tyrosine kinase expression in human lung cancer cell lines correlates with cellular adhesion. European Journal of Cancer 37:17, pages 2264-2274.
Crossref
Dan R Robinson, Yi-Mi Wu & Su-Fang Lin. (2000) The protein tyrosine kinase family of the human genome. Oncogene 19:49, pages 5548-5557.
Crossref

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