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Original Article

Histological Methods to Determine Blood Flow Distribution with Fluorescent Microspheres

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Pages 291-309 | Received 06 Oct 1997, Accepted 09 Jun 1998, Published online: 12 Jul 2009

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Tongalp H. Tezel, Ewa Bodek, Kenan Sönmez, Sankar Kaliappan, Henry J. Kaplan, Zhiwei Hu & Alan Garen. (2007) Targeting Tissue Factor for Immunotherapy of Choroidal Neovascularization by Intravitreal Delivery of Factor VII-Fc Chimeric Antibody. Ocular Immunology and Inflammation 15:1, pages 3-10.
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Tobias Könemann, Nicole J. Savage, J. Alex Huffman & Christopher Pöhlker. (2018) Characterization of steady-state fluorescence properties of polystyrene latex spheres using off- and online spectroscopic methods. Atmospheric Measurement Techniques 11:7, pages 3987-4003.
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Isaac P. Pinar & Heather D. Jones. (2018) Novel imaging approaches for small animal models of lung disease (2017 Grover Conference series). Pulmonary Circulation 8:2, pages 1-9.
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Xiaoyu Ma, Taoran Wang, Donghui Song, Derek Hargrove, Qiuchen Dong, Zhu Luo, Jun Chen, Xiuling Lu, Yangchao Luo, Tai-Hsi Fan & Yu Lei. (2016) Protein Microspheres with Unique Green and Red Autofluorescence for Noninvasively Tracking and Modeling Their in Vivo Biodegradation. ACS Biomaterials Science & Engineering 2:6, pages 954-962.
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Gabor Patonay, Garfield Beckford & Pekka Hänninen. 2014. Handbook of Spectroscopy. Handbook of Spectroscopy 999 1036 .
Brendan A.S. McIntyre, Cantas Alev, Rami Mechael, Kyle R. Salci, Jung Bok Lee, Aline Fiebig-Comyn, Borhane Guezguez, Yuping Wu, Guojun Sheng & Mickie Bhatia. (2014) Expansive Generation of Functional Airway Epithelium From Human Embryonic Stem Cells. Stem Cells Translational Medicine 3:1, pages 7-17.
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Rickson C. Mesquita, Angela D’Souza, Thomas V. Bilfinger, Robert M. Galler, Asher Emanuel, Steven S. Schenkel, Arjun G. Yodh & Thomas F. Floyd. (2013) Optical Monitoring and Detection of Spinal Cord Ischemia. PLoS ONE 8:12, pages e83370.
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Melissa A. KruegerSabine S. HukeRobb W. Glenny. (2013) Visualizing Regional Myocardial Blood Flow in the Mouse. Circulation Research 112:9.
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Susan R. Hopkins & G. Kim Prisk. (2010) Lung perfusion measured using magnetic resonance imaging: New tools for physiological insights into the pulmonary circulation. Journal of Magnetic Resonance Imaging 32:6, pages 1287-1301.
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Stephanie A. Eucker, Brenton D. Hoffman, Rahul Natesh, Jill Ralston, William M. Armstead & Susan S. Margulies. (2010) Development of a fluorescent microsphere technique for rapid histological determination of cerebral blood flow. Brain Research 1326, pages 128-134.
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S.G. Emeigh Hart. 2010. Comprehensive Toxicology. Comprehensive Toxicology 263 303 .
W. Wei, L.-Y. Wang, L. Yuan, Q. Wei, X.-D. Yang, Z.-G. Su & G.-H. Ma. (2007) Preparation and Application of Novel Microspheres Possessing Autofluorescent Properties. Advanced Functional Materials 17:16, pages 3153-3158.
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Dino J. Ravnic, Yu‐Zhong Zhang, Aslihan Turhan, Akira Tsuda, Juan P. Pratt, Harold T. Huss & Steven J. Mentzer. (2007) Biological and Optical Properties of Fluorescent Nanoparticles Developed for Intravascular Imaging. Microscopy Research and Technique 70:9, pages 776-781.
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Robb W. Glenny, Susan L. Bernard, Daniel L. Luchtel, Blazej Neradilek & Nayak L. Polissar. (2007) The spatial-temporal redistribution of pulmonary blood flow with postnatal growth. Journal of Applied Physiology 102:3, pages 1281-1288.
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G De Visscher, M Haseldonckx & W Flameng. (2006) Fluorescent microsphere technique to measure cerebral blood flow in the rat. Nature Protocols 1:4, pages 2162-2170.
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Dino J. Ravnic, Yu-Zhong Zhang, Akira Tsuda, Juan P. Pratt, Harold T. Huss & Steven J. Mentzer. (2006) Multi-image particle tracking velocimetry of the microcirculation using fluorescent nanoparticles. Microvascular Research 72:1-2, pages 27-33.
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Gaspard Montandon, Richard Kinkead, Anne-Marie Lomenech, Aïda Bairam & Hervé Guénard. (2006) Heterogeneity of brainstem blood flow response to hypoxia in the anesthetized rat. Respiratory Physiology & Neurobiology 150:2-3, pages 301-306.
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M Marxen, C Paget, L X Yu & R M Henkelman. (2006) Estimating perfusion using microCT to locate microspheres. Physics in Medicine and Biology 51:1, pages N9-N16.
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Tirath Y. Patel, David M. Hovsepian & James R. Duncan. (2006) Measurement of Blood Flow Before and After Embolization with Use of Fluorescent Microspheres in an Animal Model. Journal of Vascular and Interventional Radiology 17:1, pages 103-111.
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Gaspard Montandon, Richard Kinkead, Anne-Marie Lomenech, Aïda Bairam & Hervé Guénard. (2005) Heterogeneity of brainstem blood flow response to hypoxia in the anesthetized rat. Respiratory Physiology & Neurobiology 147:1, pages 117-122.
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David A. Brown, Yu Fen Chou, Ramin E. Beygui, James C.Y. Dunn & Benjamin M. Wu. (2005) Gelatin-embedded cell-polymer constructs for histological cryosectioning. Journal of Biomedical Materials Research 72B:1, pages 79-85.
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J Hamoir, A Nemmar, D Halloy, D Wirth, G Vincke, A Vanderplasschen, B Nemery & P Gustin. (2003) Effect of polystyrene particles on lung microvascular permeability in isolated perfused rabbit lungs: role of size and surface properties. Toxicology and Applied Pharmacology 190:3, pages 278-285.
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Elizabeth M. Wagner & Robert H. Brown. (2002) Blood flow distribution within the airway wall. Journal of Applied Physiology 92:5, pages 1964-1969.
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Robb W. Glenny, Susan L. Bernard & Wayne J. Lamm. (2000) Hemodynamic effects of 15-μm-diameter microspheres on the rat pulmonary circulation. Journal of Applied Physiology 89:2, pages 499-504.
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Nayak L. Polissar, Derek C. Stanford & Robb W. Glenny. (2000) The 400 microsphere per piece “rule” does not apply to all blood flow studies. American Journal of Physiology-Heart and Circulatory Physiology 278:1, pages H16-H25.
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