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Journal of Drug Targeting Volume 18, 2010 - Issue 9
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Original Article

Targeting of the B-lineage leukemia stem cells and their progeny with norcantharidin encapsulated liposomes modified with a novel CD19 monoclonal antibody 2E8 in vitro

Jingying ZhangDivision of Hematology-Oncology, Zhejiang Key Laboratory for Neonatal Diseases, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou 310003, People’s Republic of China
,
Yongmin TangDivision of Hematology-Oncology, Zhejiang Key Laboratory for Neonatal Diseases, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou 310003, People’s Republic of ChinaCorrespondence[email protected]
,
Sisi LiDivision of Hematology-Oncology, Zhejiang Key Laboratory for Neonatal Diseases, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou 310003, People’s Republic of China
,
Chan LiaoDivision of Hematology-Oncology, Zhejiang Key Laboratory for Neonatal Diseases, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou 310003, People’s Republic of China
&
Xiaoping GuoDivision of Hematology-Oncology, Zhejiang Key Laboratory for Neonatal Diseases, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou 310003, People’s Republic of China
Pages 675-687 | Received 15 Oct 2009, Accepted 25 Jan 2010, Published online: 12 Mar 2010

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Jingying Zhang, Diying Shen, Min Jia, Haizhao Zhao & Yongmin Tang. (2018) The targeting effect of Hm2E8b–NCTD–liposomes on B-lineage leukaemia stem cells is associated with the HLF–SLUG axis. Journal of Drug Targeting 26:1, pages 55-65.
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Xiao-Jun Xu, Yong-Min Tang, Hai-Zhao Zhao, Li Guo & Zhu-Jun Wang. (2014) ZCH-2B8a, an antibody targeting actin-binding protein coronin-1a, is a potential therapeutic agent for B-lineage malignancies. Journal of Drug Targeting 22:6, pages 488-497.
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Articles from other publishers (15)

Guang-Gui Zeng, Jing Zhou, Wan-Li Jiang, Jiang Yu, Gui-Ying Nie, Jing Li, Shi-Qian Zhang & Chao-Ke Tang. (2024) A Potential Role of NFIL3 in Atherosclerosis. Current Problems in Cardiology 49:1, pages 102096.
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Qian Liu, Henglai Sun, Xinyu Li, Huagang Sheng & Liqiao Zhu. (2022) Strategies for Solubility and Bioavailability Enhancement and Toxicity Reduction of Norcantharidin. Molecules 27:22, pages 7740.
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Ying Jiang, Xiaolin Liu, Xinyi Tan, Ye Hou, Wanxiao Sun, Jingxin Gou, Tian Yin, Haibing He, Yu Zhang & Xing Tang. (2020) In Vitro and In Vivo Evaluation of SP94 Modified Liposomes Loaded with N-14NCTDA, a Norcantharimide Derivative for Hepatocellular Carcinoma-Targeting. AAPS PharmSciTech 21:7.
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Mohammad Houshmand, Francesca Garello, Paola Circosta, Rachele Stefania, Silvio Aime, Giuseppe Saglio & Claudia Giachino. (2020) Nanocarriers as Magic Bullets in the Treatment of Leukemia. Nanomaterials 10:2, pages 276.
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Jie Wang, Ying Zhang, Jing Xia, Tingting Cai, Jiawei Du, Jinpeng Chen, Ping Li, Yuqing Shen, Aifeng Zhang, Bo Fu, Xueren Gao, Fenqin Miao, Jianqiong Zhang & Gaojun Teng. (2018) Neuronal PirB Upregulated in Cerebral Ischemia Acts as an Attractive Theranostic Target for Ischemic Stroke. Journal of the American Heart Association 7:3.
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Xiaolin Liu, Xiaoguang Tao, Qi Zheng, Hang Xu, Yu Zhang, Tian Lei, Tian Yin, Haibing He & Xing Tang. (2017) Development and validation of an LC-ESI-MS/MS approach to determine a highly hydrophobic drug, norcantharidin palmitate, and apply to a preliminary pharmacokinetic study in rats. Biomedical Chromatography 31:12, pages e4010.
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Xiaolin Liu, Mengting Han, Jiawen Xu, Sicong Geng, Yu Zhang, Xaohui Ye, Jingxin Gou, Tian Yin, Haibing He & Xing Tang. (2017) Asialoglycoprotein receptor-targeted liposomes loaded with a norcantharimide derivative for hepatocyte-selective targeting. International Journal of Pharmaceutics 520:1-2, pages 98-110.
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Jie Gao, Wei Li, Yajun Guo & Si-Shen Feng. (2016) Nanomedicine strategies for sustained, controlled and targeted treatment of cancer stem cells. Nanomedicine 11:24, pages 3261-3282.
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Breanne Landry, Juliana Valencia-Serna, Hilal Gul-Uludag, Xiaoyan Jiang, Anna Janowska-Wieczorek, Joseph Brandwein & Hasan Uludag. (2015) Progress in RNAi-mediated Molecular Therapy of Acute and Chronic Myeloid Leukemia. Molecular Therapy - Nucleic Acids 4, pages e240.
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Diying ShenYongmin TangSisi LiWeiqun XuLingyan Zhang. (2014) Successful Construction and Massive Expression of a Novel Anti-CD19 Human-Mouse Chimeric Antibody Hm2E8b. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 33:4, pages 215-220.
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Jie Zheng, Wei Du, Lai-jun Song, Rui Zhang, Lai-guang Sun, Feng-guo Chen & Xin-ting Wei. (2014) Norcantharidin induces growth inhibition and apoptosis of glioma cells by blocking the Raf/MEK/ERK pathway. World Journal of Surgical Oncology 12:1, pages 207.
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Vinu Krishnan, Xian Xu, Sonali P. Barwe, Xiaowei Yang, Kirk Czymmek, Scott A. Waldman, Robert W. Mason, Xinqiao Jia & Ayyappan K. Rajasekaran. (2012) Dexamethasone-Loaded Block Copolymer Nanoparticles Induce Leukemia Cell Death and Enhance Therapeutic Efficacy: A Novel Application in Pediatric Nanomedicine. Molecular Pharmaceutics 10:6, pages 2199-2210.
Crossref
Chen-Hsi Hsieh, K. S. Clifford Chao, Hui-Fen Liao & Yu-Jen Chen. (2013) Norcantharidin, Derivative of Cantharidin, for Cancer Stem Cells. Evidence-Based Complementary and Alternative Medicine 2013, pages 1-11.
Crossref
Manuela Calin. 2012. Antibody-Mediated Drug Delivery Systems. Antibody-Mediated Drug Delivery Systems 229 266 .
Kedong Lu, Mingzhuo Cao, Weiwei Mao, Xuanrong Sun, Jianbin Tang, Youqing Shen & Meihua Sui. (2012) Targeted acid-labile conjugates of norcantharidin for cancer chemotherapy. Journal of Materials Chemistry 22:31, pages 15804.
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