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Research Article

Dissolving microneedles to obtain rapid local anesthetic effect of lidocaine at skin tissue

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Pages 770-775 | Received 08 Mar 2013, Accepted 31 May 2013, Published online: 01 Jul 2013

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Read on this site (4)

Chuanyu Chen & Peijun You. (2017) A novel local anesthetic system: transcriptional transactivator peptide-decorated nanocarriers for skin delivery of ropivacaine. Drug Design, Development and Therapy 11, pages 1941-1949.
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Yukako Ito, Shinji Kobuchi, Genta Inoue, Eisaku Kakumu, Miki Aoki, Toshiyuki Sakaeda & Kanji Takada. (2017) Dissolving microneedles for enhanced local delivery of capsaicin to rat skin tissue. Journal of Drug Targeting 25:5, pages 420-424.
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Atul Nayak, Hiten Babla, Tao Han & Diganta Bhusan Das. (2016) Lidocaine carboxymethylcellulose with gelatine co-polymer hydrogel delivery by combined microneedle and ultrasound. Drug Delivery 23:2, pages 658-669.
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N. Sanoj Rejinold, Ju-Hyung Shin, Hae Yong Seok & Yeu-Chun Kim. (2016) Biomedical applications of microneedles in therapeutics: recent advancements and implications in drug delivery. Expert Opinion on Drug Delivery 13:1, pages 109-131.
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Articles from other publishers (15)

Vineet Kumar Rai, Ivy Saha, Mahboob Alam, Kumar Nishchaya, Goutam Ghosh & Goutam Rath. (2023) Microneedle arrays for cutaneous and transcutaneous drug delivery, disease diagnosis, and cosmetic aid. Journal of Drug Delivery Science and Technology 79, pages 104058.
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Tânia M. T. Guimarães, Tânia Moniz, Cláudia Nunes, Maya Margaritova Zaharieva, Mila Kaleva, Krassimira Yoncheva, Hristo Najdenski, Sofia A. Costa Lima & Salette Reis. (2022) Polymeric Microneedles for Transdermal Delivery of Rivastigmine: Design and Application in Skin Mimetic Model. Pharmaceutics 14:4, pages 752.
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Tingting Zhu, Xixi Yu, Xin Yi, Xiaoli Guo, Longhao Li, Yuanping Hao & Wanchun Wang. (2022) Lidocaine-Loaded Hyaluronic Acid Adhesive Microneedle Patch for Oral Mucosal Topical Anesthesia. Pharmaceutics 14:4, pages 686.
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Chisong Lee, Jinkyung Kim, Daniel Junmin Um, Youseong Kim, Hye Su Min, Jiwoo Shin, Jee Hye Nam, Geonwoo Kang, Mingyu Jang, Huisuk Yang & Hyungil Jung. (2021) Optimization of Layered Dissolving Microneedle for Sustained Drug Delivery Using Heat-Melted Poly(Lactic-Co-glycolic Acid). Pharmaceutics 13:7, pages 1058.
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Huisuk Yang, Geonwoo Kang, Mingyu Jang, Daniel Junmin Um, Jiwoo Shin, Hyeonjun Kim, Jintae Hong, Hyunji Jung, Hyemyoung Ahn, Seongdae Gong, Chisong Lee, Ui-Won Jung & Hyungil Jung. (2020) Development of Lidocaine-Loaded Dissolving Microneedle for Rapid and Efficient Local Anesthesia. Pharmaceutics 12:11, pages 1067.
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O. Olatunji & D.B. Das. 2019. Comprehensive Biotechnology. Comprehensive Biotechnology 594 614 .
Jaspreet Singh Kochhar, Justin J. Y. Tan, Yee Chin Kwang & Lifeng KangJaspreet Singh Kochhar, Justin J. Y. Tan, Yee Chin Kwang & Lifeng Kang. 2019. Microneedles for Transdermal Drug Delivery. Microneedles for Transdermal Drug Delivery 95 144 .
Qi Lei Wang, Jia Wei Ren, Bo Zhi Chen, Xuan Jin, Can Yang Zhang & Xin Dong Guo. (2018) Effect of humidity on mechanical properties of dissolving microneedles for transdermal drug delivery. Journal of Industrial and Engineering Chemistry 59, pages 251-258.
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Hyesun Jun, Myun-Hwan Ahn, In-Jeong Choi, Seung-Ki Baek, Jung-Hwan Park & Seong-O Choi. (2018) Immediate separation of microneedle tips from base array during skin insertion for instantaneous drug delivery. RSC Advances 8:32, pages 17786-17796.
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Cetin Tas, Jessica C. Joyce, Hiep X. Nguyen, Padmanabhan Eangoor, Jennifer S. Knaack, Ajay K. Banga & Mark R. Prausnitz. (2017) Dihydroergotamine mesylate-loaded dissolving microneedle patch made of polyvinylpyrrolidone for management of acute migraine therapy. Journal of Controlled Release 268, pages 159-165.
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Sung-Hyun Baek, Ju-Hyung Shin & Yeu-Chun Kim. (2017) Drug-coated microneedles for rapid and painless local anesthesia. Biomedical Microdevices 19:1.
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Rubi Mahato. 2017. Emerging Nanotechnologies for Diagnostics, Drug Delivery and Medical Devices. Emerging Nanotechnologies for Diagnostics, Drug Delivery and Medical Devices 331 353 .
O. Olatunji & D.B. Das. 2015. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Yunzhe Ma & Harvinder S. Gill. (2014) Coating Solid Dispersions on Microneedles via a Molten Dip‐Coating Method: Development and In Vitro Evaluation for Transdermal Delivery of a Water‐Insoluble Drug. Journal of Pharmaceutical Sciences 103:11, pages 3621-3630.
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Atul Nayak, Diganta B. Das & Goran T. Vladisavljević. (2013) Microneedle-Assisted Permeation of Lidocaine Carboxymethylcellulose with Gelatine Co-polymer Hydrogel. Pharmaceutical Research 31:5, pages 1170-1184.
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