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Journal of Drug Targeting Volume 21, 2013 - Issue 8
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Research Article

Intranasal delivery of cyclobenzaprine hydrochloride-loaded thiolated chitosan nanoparticles for pain relief

Deepa PatelTIFAC CORE IN NDDS, Pharmacy Department, Faculty of Technology and Engineering, Kalabhavan, The Maharaja Sayajirao University of Baroda Vadodara, GujaratIndia
,
Sachin NaikTIFAC CORE IN NDDS, Pharmacy Department, Faculty of Technology and Engineering, Kalabhavan, The Maharaja Sayajirao University of Baroda Vadodara, GujaratIndia
,
Krishna ChuttaniInstitute of Nuclear Medicine and Allied Sciences Timarpur, DelhiIndia
,
Rashi MathurInstitute of Nuclear Medicine and Allied Sciences Timarpur, DelhiIndia
,
Anil K. MishraInstitute of Nuclear Medicine and Allied Sciences Timarpur, DelhiIndia
&
Ambikanandan MisraTIFAC CORE IN NDDS, Pharmacy Department, Faculty of Technology and Engineering, Kalabhavan, The Maharaja Sayajirao University of Baroda Vadodara, GujaratIndiaCorrespondence[email protected]
Pages 759-769 | Received 05 Mar 2013, Accepted 16 Jun 2013, Published online: 24 Jul 2013

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Ankit Javia & Hetal Thakkar. (2017) Intranasal delivery of tapentadol hydrochloride–loaded chitosan nanoparticles: formulation, characterisation and its in vivo evaluation. Journal of Microencapsulation 34:7, pages 644-658.
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Siji Lv, Peng Quan, Wei Wang & Liang Fang. (2016) Two steps modification for improvement of cyclobenzaprine transdermal delivery: releasing from patch and penetrating through skin. Drug Development and Industrial Pharmacy 42:12, pages 2070-2077.
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Articles from other publishers (23)

Sushmita VishwakarmaNaveen GuptaNeeraj SharmaDharmendra S. RajputAnkita Shukla. (2023) Formulation and Evaluation of Mucoadhesive In-situ Nasal Gel of Tramadol Hydrochloride. Research Journal of Pharmaceutical Dosage Forms and Technology, pages 131-137.
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Nausaba MoazzamNaveen GuptaNeeraj SharmaDharmendra S. RajputAnkita Shukla. (2023) Design, Development and Formulation of Mucoadhesive In-situ Nasal Gel of Meperidine Hydrochloride. Research Journal of Pharmaceutical Dosage Forms and Technology, pages 102-108.
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Vanshita Singh, Akash Garg, Rajeev Sharma & Hitesh Kumar Dewangan. (2023) Recent Advances of Nanotechnology in Brain Targeting. Current Nanoscience 19:3, pages 350-361.
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Yogesh Garg, Deepak N. Kapoor, Abhishek K. Sharma & Amit Bhatia. (2022) Drug Delivery Systems and Strategies to Overcome the Barriers of Brain. Current Pharmaceutical Design 28:8, pages 619-641.
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Robert A. Yokel. (2021) Direct nose to the brain nanomedicine delivery presents a formidable challenge. WIREs Nanomedicine and Nanobiotechnology 14:2.
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Shin Hyuk Yoo, Hae-Won Kim & Jun Hee Lee. (2022) Restoration of olfactory dysfunctions by nanomaterials and stem cells-based therapies: Current status and future perspectives. Journal of Tissue Engineering 13, pages 204173142210834.
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David Lee & Tamara Minko. (2021) Nanotherapeutics for Nose-to-Brain Drug Delivery: An Approach to Bypass the Blood Brain Barrier. Pharmaceutics 13:12, pages 2049.
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R. Majumder, T. Pal, A. Basumallick & Chitrangada Das Mukhopadhyay. (2021) Functionalized carbon nano onion as a novel drug delivery system for brain targeting. Journal of Drug Delivery Science and Technology 63, pages 102414.
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Shiv Bahadur & Kamla Pathak. 2021. Direct Nose-to-Brain Drug Delivery. Direct Nose-to-Brain Drug Delivery 187 207 .
Ravindra V. Badhe & Sonali S. Nipate. 2020. Bioadhesives in Drug Delivery. Bioadhesives in Drug Delivery 259 305 .
Doddy Denise Ojeda-Hernández, Alejandro A. Canales-Aguirre, Jorge Matias-Guiu, Ulises Gomez-Pinedo & Juan C. Mateos-Díaz. (2020) Potential of Chitosan and Its Derivatives for Biomedical Applications in the Central Nervous System. Frontiers in Bioengineering and Biotechnology 8.
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Ramin Ansari, Seyed Mahdi Sadati, Negin Mozafari, Hajar Ashrafi & Amir Azadi. (2020) Carbohydrate polymer-based nanoparticle application in drug delivery for CNS-related disorders. European Polymer Journal 128, pages 109607.
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S Kumbham, V. Ghate & S. A. Lewis. (2019) APPROACHES FOR THE DELIVERY OF SKELETAL MUSCLE RELAXANTS: A REVIEW. INDIAN DRUGS 56:07, pages 7-15.
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Vassilis Bourganis, Olga Kammona, Aleck Alexopoulos & Costas Kiparissides. (2018) Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics. European Journal of Pharmaceutics and Biopharmaceutics 128, pages 337-362.
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Fabio Sonvico, Adryana Clementino, Francesca Buttini, Gaia Colombo, Silvia Pescina, Silvia Stanisçuaski Guterres, Adriana Raffin Pohlmann & Sara Nicoli. (2018) Surface-Modified Nanocarriers for Nose-to-Brain Delivery: From Bioadhesion to Targeting. Pharmaceutics 10:1, pages 34.
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Patrícia C. Pires & Adriana O. Santos. (2018) Nanosystems in nose-to-brain drug delivery: A review of non-clinical brain targeting studies. Journal of Controlled Release 270, pages 89-100.
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Siji Lv, Peng Quan, Xiaochang Liu & Liang Fang. (2016) Effect of backing films on the transdermal delivery of cyclobenzaprine patch. Asian Journal of Pharmaceutical Sciences 11:6, pages 780-783.
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Marcella Mauro, Matteo Crosera, Massimo Bovenzi, Gianpiero Adami & Francesca Larese Filon. (2016) Pilot study on in vitro silver nanoparticles permeation through meningeal membrane. Colloids and Surfaces B: Biointerfaces 146, pages 245-249.
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B. Bernocchi, R. Carpentier, I. Lantier, C. Ducournau, I. Dimier-Poisson & D. Betbeder. (2016) Mechanisms allowing protein delivery in nasal mucosa using NPL nanoparticles. Journal of Controlled Release 232, pages 42-50.
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Giovanna Rassu, Elena Soddu, Massimo Cossu, Elisabetta Gavini, Paolo Giunchedi & Alessandro Dalpiaz. (2016) Particulate formulations based on chitosan for nose-to-brain delivery of drugs. A review. Journal of Drug Delivery Science and Technology 32, pages 77-87.
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Ya-Han Li, Ching-Yi Cheng, Nan-Kai Wang, Hsin-Yuan Tan, Yueh-Ju Tsai, Ching-Hsi Hsiao, David Hui-Kang Ma & Lung-Kun Yeh. (2015) Characterization of the modified chitosan membrane cross-linked with genipin for the cultured corneal epithelial cells. Colloids and Surfaces B: Biointerfaces 126, pages 237-244.
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Chenxi Li, Chunyan Li, Zheshuo Liu, Qiuhong Li, Xueying Yan, Yu Liu & Weiyue Lu. (2014) Enhancement in bioavailability of ketorolac tromethamine via intranasal in situ hydrogel based on poloxamer 407 and carrageenan. International Journal of Pharmaceutics 474:1-2, pages 123-133.
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Luca Casettari & Lisbeth Illum. (2014) Chitosan in nasal delivery systems for therapeutic drugs. Journal of Controlled Release 190, pages 189-200.
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