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Journal of Drug Targeting Volume 22, 2014 - Issue 4
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Original Article

Improvement of solubility and targetability of radioiodinated hypericin by using sodium cholate based solvent in rat models of necrosis

Yun Jia Department of Natural Medicinal Chemistry, China Pharmaceutical UniversityNanjing, Jiangsu ProvinceP.R. China;b Laboratory of Translational Medicine, Jiangsu Province Academy of Traditional Chinese MedicineNanjing, Jiangsu ProvinceP.R. China
,
Ying Zhanc Zhongda Hospital of Southeast UniversityNanjing, Jiangsu ProvinceP.R. China
,
Cuihua Jiangb Laboratory of Translational Medicine, Jiangsu Province Academy of Traditional Chinese MedicineNanjing, Jiangsu ProvinceP.R. China
,
Xiao Jiangb Laboratory of Translational Medicine, Jiangsu Province Academy of Traditional Chinese MedicineNanjing, Jiangsu ProvinceP.R. China
,
Meng Gaob Laboratory of Translational Medicine, Jiangsu Province Academy of Traditional Chinese MedicineNanjing, Jiangsu ProvinceP.R. China
,
Wei Liud Department of Nuclear Medicine, The First Affiliated Hospital of Nanjing Medical UniversityNanjing, Jiangsu ProvinceP.R. China
,
Yue Lib Laboratory of Translational Medicine, Jiangsu Province Academy of Traditional Chinese MedicineNanjing, Jiangsu ProvinceP.R. China
,
Junhu Wanga Department of Natural Medicinal Chemistry, China Pharmaceutical UniversityNanjing, Jiangsu ProvinceP.R. China;b Laboratory of Translational Medicine, Jiangsu Province Academy of Traditional Chinese MedicineNanjing, Jiangsu ProvinceP.R. China
,
Qingqing Wanga Department of Natural Medicinal Chemistry, China Pharmaceutical UniversityNanjing, Jiangsu ProvinceP.R. China;b Laboratory of Translational Medicine, Jiangsu Province Academy of Traditional Chinese MedicineNanjing, Jiangsu ProvinceP.R. China
,
Marlein Miranda Conae KU Leuven, Faculty of MedicineHerestraat, LeuvenBelgium
,
Nan Yaoa Department of Natural Medicinal Chemistry, China Pharmaceutical UniversityNanjing, Jiangsu ProvinceP.R. China
,
Xiaoning Wangb Laboratory of Translational Medicine, Jiangsu Province Academy of Traditional Chinese MedicineNanjing, Jiangsu ProvinceP.R. China
,
Zhijun Fangb Laboratory of Translational Medicine, Jiangsu Province Academy of Traditional Chinese MedicineNanjing, Jiangsu ProvinceP.R. China
,
Zhiqi Yina Department of Natural Medicinal Chemistry, China Pharmaceutical UniversityNanjing, Jiangsu ProvinceP.R. ChinaCorrespondence[email protected]
,
Jian Zhangb Laboratory of Translational Medicine, Jiangsu Province Academy of Traditional Chinese MedicineNanjing, Jiangsu ProvinceP.R. ChinaCorrespondence[email protected]
,
Ziping Sunf Shandong Academy of Medical SciencesJinan, ShandongP.R. China
&
Yicheng Nib Laboratory of Translational Medicine, Jiangsu Province Academy of Traditional Chinese MedicineNanjing, Jiangsu ProvinceP.R. China;e KU Leuven, Faculty of MedicineHerestraat, LeuvenBelgium
 show all
Pages 304-312 | Received 30 Aug 2013, Accepted 18 Nov 2013, Published online: 13 Dec 2013

Citations (14)

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Read on this site (4)

Dongjian Zhang, Qiaomei Jin, Yicheng Ni & Jian Zhang. (2020) Discovery of necrosis avidity of rhein and its applications in necrosis imaging. Journal of Drug Targeting 28:9, pages 904-912.
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Yue Li, Xuejiao Liu, Dongjian Zhang, Bin Lou, Fei Peng, Xiaoning Wang, Xin Shan, Cuihua Jiang, Meng Gao, Ziping Sun, Yicheng Ni, Dejian Huang & Jian Zhang. (2015) Evaluation of a metalloporphyrin (THPPMnCl) for necrosis-affinity in rat models of necrosis. Journal of Drug Targeting 23:10, pages 926-935.
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Marlein Miranda Cona, Yuanbo Feng, Jian Zhang, Yue Li, Alfons Verbruggen, Raymond Oyen & Yicheng Ni. (2015) Sodium cholate, a solubilizing agent for the necrosis avid radioiodinated hypericin in rabbits with acute myocardial infarction. Drug Delivery 22:3, pages 427-435.
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Dongjian Zhang, Dejian Huang, Yun Ji, Cuihua Jiang, Yue Li, Meng Gao, Nan Yao, Xuejiao Liu, Haibo Shao, Su Jing, Yicheng Ni, Zhiqi Yin & Jian Zhang. (2015) Experimental evaluation of radioiodinated sennoside B as a necrosis-avid tracer agent. Journal of Drug Targeting 23:2, pages 180-190.
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Articles from other publishers (10)

Yue Li, Shuncong Wang, Xiao Jiang, Xiaoxiong Wang, Xiang Zhou, Liangrong Wan, Haitao Zhao, Zhaoli Zhou, LingJie Gao, Gang Huang, Yicheng Ni & Xiaoyan He. (2021) Preparation and validation of cyclodextrin-based excipients for radioiodinated hypericin applied in a targeted cancer radiotherapy. International Journal of Pharmaceutics 599, pages 120393.
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Marcus C. M. Stroet, Erik de Blois, Debra C. Stuurman, Corrina M. A. de Ridder, Joost Haeck, Yann Seimbille, Laura Mezzanotte, Marion de Jong, Clemens W. G. M. Löwik & Kranthi M. Panth. (2020) In Vivo Evaluation of Indium-111–Labeled 800CW as a Necrosis-Avid Contrast Agent. Molecular Imaging and Biology 22:5, pages 1333-1341.
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Aimi Zhang, Tianze Wu, Li Bian, Panli Li, Qiufang Liu, Dongjian Zhang, Qiaomei Jin, Jian Zhang, Gang Huang & Shaoli Song. (2019) Synthesis and Evaluation of Ga-68-Labeled Rhein for Early Assessment of Treatment-Induced Tumor Necrosis. Molecular Imaging and Biology 22:3, pages 515-525.
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Dongjian Zhang, Meng Gao, Qiaomei Jin, Yicheng Ni & Jian Zhang. (2019) Updated developments on molecular imaging and therapeutic strategies directed against necrosis. Acta Pharmaceutica Sinica B 9:3, pages 455-468.
Crossref
Anna A. Rybczynska, Hendrikus H. Boersma, Steven de Jong, Jourik A. Gietema, Walter Noordzij, Rudi A. J. O. Dierckx, Philip H. Elsinga & Aren van Waarde. (2018) Avenues to molecular imaging of dying cells: Focus on cancer. Medicinal Research Reviews 38:6, pages 1713-1768.
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Qiufang Liu, Yuyi Qian, Panli Li, Sihang Zhang, Zerong Wang, Jianjun Liu, Xiaoguang Sun, Michael Fulham, Dagan Feng, Zhigang Chen, Shaoli Song, Wei Lu & Gang Huang. (2018) The combined therapeutic effects of 131iodine-labeled multifunctional copper sulfide-loaded microspheres in treating breast cancer. Acta Pharmaceutica Sinica B 8:3, pages 371-380.
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Xinghua Duan, Zhiqi Yin, Cuihua Jiang, Qiaomei Jin, Dongjian Zhang, Ziping Sun, Wencai Ye & Jian Zhang. (2017) Radioiodinated hypericin disulfonic acid sodium salts as a DNA-binding probe for early imaging of necrotic myocardium. European Journal of Pharmaceutics and Biopharmaceutics 117, pages 151-159.
Crossref
Jindian Li, Jian Zhang, Shengwei Yang, Cuihua Jiang, DongJian Zhang, Qiaomei Jin, Qin Wang, Cong Wang, Yicheng Ni, Zhiqi Yin & Shaoli Song. (2015) Synthesis and Preclinical Evaluation of Radioiodinated Hypericin Dicarboxylic Acid as a Necrosis Avid Agent in Rat Models of Induced Hepatic, Muscular, and Myocardial Necroses. Molecular Pharmaceutics 13:1, pages 232-240.
Crossref
Yue Li, Cuihua Jiang, Xiao Jiang, Ziping Sun, Marlein Miranda Cona, Wei Liu, Jian Zhang & Yicheng Ni. (2015) Biliary and duodenal drainage for reducing the radiotoxic risk of antineoplastic 131 I-hypericin in rat models . Experimental Biology and Medicine 240:12, pages 1764-1773.
Crossref
Xiaojun Qi, Haibo Shao, Jian Zhang, Ziping Sun, Yicheng Ni & Ke Xu. (2014) Radiopharmaceutical study on Iodine-131-labelled hypericin in a canine model of hepatic RFA-induced coagulative necrosis. La radiologia medica 120:2, pages 213-221.
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