Advanced search
Publication Cover
Journal of Drug Targeting Volume 23, 2015 - Issue 9
Submit an article Journal homepage
478
Views
47
CrossRef citations to date
0
Altmetric
Original Article

Traumatic brain injury opens blood–brain barrier to stealth liposomes via an enhanced permeability and retention (EPR)-like effect

Ben J. BoydDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia, ;ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia, Correspondence[email protected]
,
Adam GalleAustralian Centre for Blood Diseases, Monash University Alfred Hospital, Melbourne, VIC, Australia, ;Molecular Neurotrauma and Haemostasis, Central Clinical School, Monash University, VIC, Australia,
,
Maria DaglasAustralian Centre for Blood Diseases, Monash University Alfred Hospital, Melbourne, VIC, Australia, ;Molecular Neurotrauma and Haemostasis, Central Clinical School, Monash University, VIC, Australia,
,
Jeffrey V. RosenfeldDepartment of Surgery, Monash University Alfred Hospital, Melbourne, VIC, Australia, ;F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA, and ;Monash Institute of Medical Engineering, Monash University, Melbourne, VIC, Australia
&
Robert MedcalfAustralian Centre for Blood Diseases, Monash University Alfred Hospital, Melbourne, VIC, Australia, ;Molecular Neurotrauma and Haemostasis, Central Clinical School, Monash University, VIC, Australia, Correspondence[email protected]
Pages 847-853 | Received 09 Jan 2015, Accepted 21 Mar 2015, Published online: 16 Jun 2015

Citations (47)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Feng Lin, Yixuan Liu, Wenqi Luo, Shuhan Liu, Yiming Wang, Rui Gu, Wanguo Liu & Chunsheng Xiao. (2022) Minocycline-Loaded Poly(α-Lipoic Acid)–Methylprednisolone Prodrug Nanoparticles for the Combined Anti-Inflammatory Treatment of Spinal Cord Injury. International Journal of Nanomedicine 17, pages 91-104.
Read now
Andrea Perrelli, Parisa Fatehbasharzad, Valerio Benedetti, Chiara Ferraris, Marco Fontanella, Elisa De Luca, Mauro Moglianetti, Luigi Battaglia & Saverio Francesco Retta. (2021) Towards precision nanomedicine for cerebrovascular diseases with emphasis on Cerebral Cavernous Malformation (CCM). Expert Opinion on Drug Delivery 18:7, pages 849-876.
Read now
Po-Wah So, Antigoni Ekonomou, Kim Galley, Leigh Brody, Meliz Sahuri-Arisoylu, Ivan Rattray, Diana Cash & Jimmy D Bell. (2019) Intraperitoneal delivery of acetate-encapsulated liposomal nanoparticles for neuroprotection of the penumbra in a rat model of ischemic stroke. International Journal of Nanomedicine 14, pages 1979-1991.
Read now
Mostafa Heidari Majd, Abolfazl Akbarzadeh & Azam Sargazi. (2017) Evaluation of host–guest system to enhance the tamoxifen efficiency . Artificial Cells, Nanomedicine, and Biotechnology 45:3, pages 441-447.
Read now

Articles from other publishers (43)

Xingshuang Song, Yizhi Zhang, Ziyan Tang & Lina Du. (2024) Advantages of nanocarriers for basic research in the field of traumatic brain injury. Neural Regeneration Research 19:2, pages 237-245.
Crossref
Mohammad Amin Rajizadeh, Sina Motamedy, Yousof Mir, Faezeh Akhgarandouz, Mohammad Hadi Nematollahi & Akram Nezhadi. (2023) A comprehensive and updated review on the applications of vesicular drug delivery systems in treatment of brain disorders: A shelter against storms. Journal of Drug Delivery Science and Technology 89, pages 105011.
Crossref
Shristi Arya, Deepankar Bahuguna, Gopal Bajad, Soham Loharkar, Pawan Devangan, Dharmendra Kumar Khatri, Shashi Bala Singh & Jitender Madan. (2023) Colloidal therapeutics in the management of traumatic brain injury: Portray of biomarkers and drug-targets, preclinical and clinical pieces of evidence and future prospects. Colloids and Surfaces B: Biointerfaces 230, pages 113509.
Crossref
Miranda D. Diaz, Rebecca M. Kandell, Jason R. Wu, Alexander Chen, Karen L. Christman & Ester J. Kwon. (2023) Infusible Extracellular Matrix Biomaterial Promotes Vascular Integrity and Modulates the Inflammatory Response in Acute Traumatic Brain Injury. Advanced Healthcare Materials.
Crossref
Julia A. Kudryashev, Marianne I. Madias, Rebecca M. Kandell, Queenie X. Lin & Ester J. Kwon. (2023) An Activity‐Based Nanosensor for Minimally‐Invasive Measurement of Protease Activity in Traumatic Brain Injury. Advanced Functional Materials 33:28.
Crossref
Jason R. Wu, Yazmin Hernandez, Katelyn F. Miyasaki & Ester J. Kwon. (2023) Engineered nanomaterials that exploit blood-brain barrier dysfunction for delivery to the brain. Advanced Drug Delivery Reviews 197, pages 114820.
Crossref
Aria W. Tarudji, Hunter A. Miller, Evan T. Curtis, Christopher L. Porter, Gary L. Madsen & Forrest M. Kievit. (2023) Sex-based differences of antioxidant enzyme nanoparticle effects following traumatic brain injury. Journal of Controlled Release 355, pages 149-159.
Crossref
Weiquan Gong, Tianhui Zhang, Mingxue Che, Yongjie Wang, Chuanyu He, Lidi Liu, Zhenshan Lv, Chunsheng Xiao, Hao Wang & Shaokun Zhang. (2023) Recent advances in nanomaterials for the treatment of spinal cord injury. Materials Today Bio 18, pages 100524.
Crossref
Lauren E. Waggoner, Katelyn F. Miyasaki & Ester J. Kwon. (2023) Analysis of PEG-lipid anchor length on lipid nanoparticle pharmacokinetics and activity in a mouse model of traumatic brain injury. Biomaterials Science.
Crossref
Lauren E. Waggoner, Jinyoung Kang, Jonathan M. Zuidema, Sanahan Vijayakumar, Alan A. Hurtado, Michael J. Sailor & Ester J. Kwon. (2022) Porous Silicon Nanoparticles Targeted to the Extracellular Matrix for Therapeutic Protein Delivery in Traumatic Brain Injury. Bioconjugate Chemistry 33:9, pages 1685-1697.
Crossref
Hau C. Kwaan. (2022) The Role of Fibrinolytic System in Health and Disease. International Journal of Molecular Sciences 23:9, pages 5262.
Crossref
Mayumi Ikeda-Imafuku, Lily Li-Wen Wang, Danika Rodrigues, Suyog Shaha, Zongmin Zhao & Samir Mitragotri. (2022) Strategies to improve the EPR effect: A mechanistic perspective and clinical translation. Journal of Controlled Release 345, pages 512-536.
Crossref
Igor Khalin, Nagappanpillai Adarsh, Martina Schifferer, Antonia Wehn, Bernhard Groschup, Thomas Misgeld, Andrey Klymchenko & Nikolaus Plesnila. (2022) Size‐Selective Transfer of Lipid Nanoparticle‐Based Drug Carriers Across the Blood Brain Barrier Via Vascular Occlusions Following Traumatic Brain Injury. Small 18:18, pages 2200302.
Crossref
He Shen, Caixia Fan, Zhifeng You, Zhifeng Xiao, Yannan Zhao & Jianwu Dai. (2021) Advances in Biomaterial‐Based Spinal Cord Injury Repair. Advanced Functional Materials 32:13.
Crossref
Hazal Ezgi Gültekin, Ezgi Oner, Miray İlhan & Merve Karpuz. 2022. Applications of Nanovesicular Drug Delivery. Applications of Nanovesicular Drug Delivery 115 148 .
Hunter A. Miller & Forrest M. Kievit. 2022. Engineering Biomaterials for Neural Applications. Engineering Biomaterials for Neural Applications 307 350 .
Rebecca M. Kandell, Julia A. Kudryashev & Ester J. Kwon. (2021) Targeting the Extracellular Matrix in Traumatic Brain Injury Increases Signal Generation from an Activity-Based Nanosensor. ACS Nano 15:12, pages 20504-20516.
Crossref
Badrul Alam Bony, Aria W. Tarudji, Hunter A. Miller, Saiprasad Gowrikumar, Sourav Roy, Evan T. Curtis, Connor C. Gee, Alex Vecchio, Punita Dhawan & Forrest M. Kievit. (2021) Claudin-1-Targeted Nanoparticles for Delivery to Aging-Induced Alterations in the Blood–Brain Barrier. ACS Nano 15:11, pages 18520-18531.
Crossref
Tianhui Zhang, Feng Lin, Wanguo Liu, Yixuan Liu, Zhihui Guo, Chunsheng Xiao, Xiuli Zhuang & Xuesi Chen. (2021) Reactive oxide species-scavenging lipid-polymer nanoparticles for neuroprotection after spinal cord injury. Applied Materials Today 24, pages 101109.
Crossref
Lauren E. Waggoner, Marianne I. Madias, Alan A. Hurtado & Ester J. Kwon. (2021) Pharmacokinetic Analysis of Peptide-Modified Nanoparticles with Engineered Physicochemical Properties in a Mouse Model of Traumatic Brain Injury. The AAPS Journal 23:5.
Crossref
Liang Han & Chen Jiang. (2021) Evolution of blood–brain barrier in brain diseases and related systemic nanoscale brain-targeting drug delivery strategies. Acta Pharmaceutica Sinica B 11:8, pages 2306-2325.
Crossref
Chiad Onyeje & Erin Lavik. (2021) Highlighting the usage of polymeric nanoparticles for the treatment of traumatic brain injury: A review study. Neurochemistry International 147, pages 105048.
Crossref
Rebecca M. Kandell, Lauren E. Waggoner & Ester J. Kwon. (2020) Nanomedicine for Acute Brain Injuries: Insight from Decades of Cancer Nanomedicine. Molecular Pharmaceutics 18:2, pages 522-538.
Crossref
Agustín J. Montivero, Marisa S. Ghersi, Johanna Catalán-Figueroa, María Lina Formica, Nahuel Camacho, Antonella F. Culasso, Claudia B. Hereñú, Santiago D. Palma & Mariela Fernanda Pérez. 2021. Psychiatry and Neuroscience Update. Psychiatry and Neuroscience Update 237 259 .
Chao Tao, Wenzhen Zhu, Jabed Iqbal, Chenjie Xu & Dong-An Wang. (2020) Stabilized albumin coatings on engineered xenografts for attenuation of acute immune and inflammatory responses. Journal of Materials Chemistry B 8:28, pages 6080-6091.
Crossref
Badrul Alam Bony, Hunter A. Miller, Aria W. Tarudji, Connor C. Gee, Anandakumar Sarella, Michael G. Nichols & Forrest M. Kievit. (2020) Ultrasmall Mixed Eu–Gd Oxide Nanoparticles for Multimodal Fluorescence and Magnetic Resonance Imaging of Passive Accumulation and Retention in TBI. ACS Omega 5:26, pages 16220-16227.
Crossref
Yi Zhang, Yulong Ou, Jia Guo & Xiaojia Huang. (2019) Retracted: Ultrasound‐triggered breast tumor sonodynamic therapy through hematoporphyrin monomethyl ether‐loaded liposome. Journal of Biomedical Materials Research Part B: Applied Biomaterials 108:3, pages 948-957.
Crossref
Julia A. Kudryashev, Lauren E. Waggoner, Hope T. Leng, Nicholas H. Mininni & Ester J. Kwon. (2020) An Activity-Based Nanosensor for Traumatic Brain Injury. ACS Sensors 5:3, pages 686-692.
Crossref
Aruna Sharma, Dafin F. Muresanu, Ala Nozari, José Vicente Lafuente, Seaab Sahib, Z. Ryan Tian, Anca D. Buzoianu, Ranjana Patnaik, Lars Wiklund & Hari Shanker Sharma. 2020. Neuropharmacology of Neuroprotection. Neuropharmacology of Neuroprotection 157 231 .
Hari Shanker Sharma, Seaab Sahib, Z. Ryan Tian, Dafin F. Muresanu, Ala Nozari, José Vicente Lafuente, Lars Wiklund & Aruna Sharma. 2020. Neuropharmacology of Neuroprotection. Neuropharmacology of Neuroprotection 233 283 .
Aria W. Tarudji & Forrest M. Kievit. 2020. Nanoparticles for Biomedical Applications. Nanoparticles for Biomedical Applications 19 36 .
Benjamin J Umlauf & Eric V Shusta. (2019) Exploiting BBB disruption for the delivery of nanocarriers to the diseased CNS. Current Opinion in Biotechnology 60, pages 146-152.
Crossref
Hunter A. Miller, Alexander W. Magsam, Aria W. Tarudji, Svetlana Romanova, Laura Weber, Connor C. Gee, Gary L. Madsen, Tatiana K. Bronich & Forrest M. Kievit. (2019) Evaluating differential nanoparticle accumulation and retention kinetics in a mouse model of traumatic brain injury via Ktrans mapping with MRI. Scientific Reports 9:1.
Crossref
Badrul Alam Bony & Forrest M. Kievit. (2019) A Role for Nanoparticles in Treating Traumatic Brain Injury. Pharmaceutics 11:9, pages 473.
Crossref
Ping Song, Chuanxu Yang, Jesper Skovhus Thomsen, Frederik Dagnæs-Hansen, Maria Jakobsen, Annemarie Brüel, Bent Deleuran & Jørgen Kjems. (2019) Lipidoid-siRNA Nanoparticle-Mediated IL-1β Gene Silencing for Systemic Arthritis Therapy in a Mouse Model. Molecular Therapy 27:8, pages 1424-1435.
Crossref
Dasom Yoo, Alexander W. Magsam, Abby M. Kelly, Patrick S. Stayton, Forrest M. Kievit & Anthony J. Convertine. (2017) Core-Cross-Linked Nanoparticles Reduce Neuroinflammation and Improve Outcome in a Mouse Model of Traumatic Brain Injury. ACS Nano 11:9, pages 8600-8611.
Crossref
Ronald Sahyouni, Paula Gutierrez, Eric Gold, Richard T Robertson & Brian J Cummings. (2017) Effects of concussion on the blood–brain barrier in humans and rodents. Journal of Concussion 1, pages 205970021668451.
Crossref
Alexander V. Kabanov & Elena V. Batrakova. 2017. Neuroimmune Pharmacology. Neuroimmune Pharmacology 847 868 .
Guido Frosina. (2016) Advances in drug delivery to high grade gliomas. Brain Pathology 26:6, pages 689-700.
Crossref
Annabelle Fülöp, Denis A. Sammour, Katrin Erich, Johanna von Gerichten, Peter van Hoogevest, Roger Sandhoff & Carsten Hopf. (2016) Molecular imaging of brain localization of liposomes in mice using MALDI mass spectrometry. Scientific Reports 6:1.
Crossref
Julia Xu, Menko Ypma, Peter A. Chiarelli, Joshua Park, Richard G. Ellenbogen, Patrick S. Stayton, Pierre D. Mourad, Donghoon Lee, Anthony J. Convertine & Forrest M. Kievit. (2016) Theranostic Oxygen Reactive Polymers for Treatment of Traumatic Brain Injury. Advanced Functional Materials 26:23, pages 4124-4133.
Crossref
Amit Ranjan Maity & David Stepensky. 2016. Intracellular Delivery III. Intracellular Delivery III 341 362 .
Rajat Sandhir, Aarti Yadav, Aditya Sunkaria & Nitin Singhal. (2015) Nano-antioxidants: An emerging strategy for intervention against neurodegenerative conditions. Neurochemistry International 89, pages 209-226.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.