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Endothelium
Journal of Endothelial Cell Research
Volume 8, 2001 - Issue 1
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Original Article

Activation of Endothelial Cell Mitogen Activated Protein Kinase ERK1/2 by Extracellular HIV-1 Tat Protein

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Pages 65-74 | Received 06 Jun 2000, Published online: 13 Jul 2009

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Jessica L. Reynolds, Supriya D. Mahajan, Ravikunar Aalinkeel, B. Nair, Donald E. Sykes & Stanley A. Schwartz. (2009) Proteomic Analyses of the Effects of Drugs of Abuse on Monocyte-Derived Mature Dendritic Cells. Immunological Investigations 38:6, pages 526-550.
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Leslie Crews, Margaret R Lentz, R Gilberto González, Howard S Fox & Eliezer Masliah. (2008) Neuronal injury in simian immunodeficiency virus and other animal models of neuroAIDS. Journal of Neurovirology 14:4, pages 327-339.
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Prue A. Hill, Michael Desmond & Robyn G. Langham. (2008) An unusual glomerulopathy in a man with HIV infection on HAART. Pathology 40:3, pages 308-310.
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Roger G Ptak. (2002) HIV-1 regulatory proteins: targets for novel drug development. Expert Opinion on Investigational Drugs 11:8, pages 1099-1115.
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Articles from other publishers (26)

Chiara Urbinati, Maria Milanesi, Nicola Lauro, Cinzia Bertelli, Guido David, Pasqualina D’Ursi, Marco Rusnati & Paola Chiodelli. (2021) HIV-1 Tat and Heparan Sulfate Proteoglycans Orchestrate the Setup of in Cis and in Trans Cell-Surface Interactions Functional to Lymphocyte Trans-Endothelial Migration. Molecules 26:24, pages 7488.
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Morteza Ghasemnejad-Berenji & Sarvin Pashapour. (2021) SARS-CoV-2 and the Possible Role of Raf/MEK/ERK Pathway in Viral Survival: Is This a Potential Therapeutic Strategy for COVID-19?. Pharmacology 106:1-2, pages 119-122.
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Ram Kumar, Nitin Khandelwal, Riyesh Thachamvally, Bhupendra Nath Tripathi, Sanjay Barua, Sudhir Kumar Kashyap, Sunil Maherchandani & Naveen Kumar. (2018) Role of MAPK/MNK1 signaling in virus replication. Virus Research 253, pages 48-61.
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Manman Dai, Min Feng, Ming Liao & Weisheng Cao. (2017) Inhibition of ERK/MAPK suppresses avian leukosis virus subgroup A and B replication. Microbial Pathogenesis 102, pages 29-35.
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Jason J Paris, Amanda N Carey, Christopher F Shay, Stacey M Gomes, Johnny J He & Jay P McLaughlin. (2013) Effects of Conditional Central Expression of HIV-1 Tat Protein to Potentiate Cocaine-Mediated Psychostimulation and Reward Among Male Mice. Neuropsychopharmacology 39:2, pages 380-388.
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Paola Chiodelli, Chiara Urbinati, Stefania Mitola, Elena Tanghetti & Marco Rusnati. (2012) Sialic Acid Associated with α v β 3 Integrin Mediates HIV-1 Tat Protein Interaction and Endothelial Cell Proangiogenic Activation . Journal of Biological Chemistry 287:24, pages 20456-20466.
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Chiara UrbinatiCosetta RavelliElena TanghettiMirella BelleriEdoardo GiacopuzziEugenio MontiMarco PrestaMarco Rusnati. (2012) Substrate-Immobilized HIV-1 Tat Drives VEGFR2/α v β 3 –Integrin Complex Formation and Polarization in Endothelial Cells . Arteriosclerosis, Thrombosis, and Vascular Biology 32:5.
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Amanda N. Carey, Elizabeth I. Sypek, Harminder D. Singh, Marc J. Kaufman & Jay P. McLaughlin. (2012) Expression of HIV-Tat protein is associated with learning and memory deficits in the mouse. Behavioural Brain Research 229:1, pages 48-56.
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Slava Rom, Marco Pacifici, Giovanni Passiatore, Susanna Aprea, Agnieszka Waligorska, Luis Del Valle & Francesca Peruzzi. (2011) HIV-1 Tat binds to SH3 domains: Cellular and viral outcome of Tat/Grb2 interaction. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1813:10, pages 1836-1844.
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Jijing Shi, Xiaolin Qin, Lin Zhao, Gongze Wang & Chaoqi Liu. (2011) Human immunodeficiency virus type 1 Tat induces B7-H1 expression via ERK/MAPK signaling pathway. Cellular Immunology 271:2, pages 280-285.
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Antonella Bugatti, Paola Chiodelli, Joseph Rosenbluh, Abraham Loyter & Marco Rusnati. (2010) BSA conjugates bearing multiple copies of the basic domain of HIV-1 Tat: Prototype for the development of multitarget inhibitors of extracellular Tat. Antiviral Research 87:1, pages 30-39.
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Suraiya Rasheed, Jasper S Yan, Adil Hussain & Bruce Lai. (2009) Proteomic characterization of HIV-modulated membrane receptors, kinases and signaling proteins involved in novel angiogenic pathways. Journal of Translational Medicine 7:1.
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Leslie Crews, Christina Patrick, Cristian Achim, Ian Everall & Eliezer Masliah. (2009) Molecular Pathology of Neuro-AIDS (CNS-HIV). International Journal of Molecular Sciences 10:3, pages 1045-1063.
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Stephan Pleschka. (2008) RNA viruses and the mitogenic Raf/MEK/ERK signal transduction cascade. bchm 389:10, pages 1273-1282.
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Cong-Xiao Lu, Jing Li, Yong-Xu Sun, Xin Qi, Qing-Juan Wang, Xian-Liang Xin & Mei-Yu Geng. (2007) Sulfated polymannuroguluronate, a novel anti-AIDS drug candidate, inhibits HIV-1 Tat-induced angiogenesis in Kaposi's sarcoma cells. Biochemical Pharmacology 74:9, pages 1330-1339.
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Massimo Mariotti, Sara Castiglioni & Jeanette A.M. Maier. (2006) Expression analysis and modulation by HIV‐Tat of the tyrosine phosphatase HD‐PTP. Journal of Cellular Biochemistry 98:2, pages 301-308.
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Bin Hui, Wei Xia, Jing Li, Limei Wang, Jing Ai & Meiyu Geng. (2006) Sulfated polymannuroguluronate, a novel anti-acquired immune deficiency syndrome drug candidate, blocks neuroinflammatory signalling by targeting the transactivator of transcription (Tat) protein. Journal of Neurochemistry 97:2, pages 334-344.
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Elena Toschi, Ilaria Bacigalupo, Raffaele Strippoli, Chiara Chiozzini, Anna Cereseto, Mario Falchi, Filomena Nappi, Cecilia Sgadari, Giovanni Barillari, Fabrizio Mainiero & Barbara Ensoli. (2006) HIV-1 Tat Regulates Endothelial Cell Cycle Progression via Activation of the Ras/ERK MAPK Signaling Pathway. Molecular Biology of the Cell 17:4, pages 1985-1994.
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Christopher A. Williams, Debasis Mondal & Krishna C. Agrawal. (2016) The HIV-1 Tat Protein Enhances Megakaryocytic Commitment of K562 Cells by Facilitating CREB Transcription Factor Coactivation by CBP. Experimental Biology and Medicine 230:11, pages 872-884.
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Wen-Rou Wong, Yu-Yun Chen, Shun-Min Yang, Yin-Li Chen & Jim-Tong Horng. (2005) Phosphorylation of PI3K/Akt and MAPK/ERK in an early entry step of enterovirus 71. Life Sciences 78:1, pages 82-90.
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Ibolya E András, Hong Pu, Jing Tian, Mária A Deli, Avindra Nath, Bernhard Hennig & Michal Toborek. (2005) Signaling Mechanisms of HIV-1 Tat-Induced Alterations of Claudin-5 Expression in Brain Endothelial Cells. Journal of Cerebral Blood Flow & Metabolism 25:9, pages 1159-1170.
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Govinder Flora, Hong Pu, Yong Woo Lee, R. Ravikumar, Avindra Nath, Bernhard Hennig & Michal Toborek. (2005) Proinflammatory synergism of ethanol and HIV-1 Tat protein in brain tissue. Experimental Neurology 191:1, pages 2-12.
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Gunnar P.H. Dietz & Mathias Bähr. (2004) Delivery of bioactive molecules into the cell: the Trojan horse approach. Molecular and Cellular Neuroscience 27:2, pages 85-131.
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James E. Kirby. (2004) Anthrax Lethal Toxin Induces Human Endothelial Cell Apoptosis. Infection and Immunity 72:1, pages 430-439.
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Govinder Flora, Yong Woo Lee, Avindra Nath, Bernhard Hennig, William Maragos & Michal Toborek. (2003) Methamphetamine Potentiates HIV-1 Tat Protein-Mediated Activation of Redox-Sensitive Pathways in Discrete Regions of the Brain. Experimental Neurology 179:1, pages 60-70.
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Honglin Luo, Bobby Yanagawa, Jingchun Zhang, Zongshu Luo, Mary Zhang, Mitra Esfandiarei, Christopher Carthy, Janet E. Wilson, Decheng Yang & Bruce M. McManus. (2002) Coxsackievirus B3 Replication Is Reduced by Inhibition of the Extracellular Signal-Regulated Kinase (ERK) Signaling Pathway. Journal of Virology 76:7, pages 3365-3373.
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