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Clinical and Experimental Hypertension Volume 37, 2015 - Issue 5
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Original Articles

YM155, a selective survivin inhibitor, reverses chronic hypoxic pulmonary hypertension in rats via upregulating voltage-gated potassium channels

Zaiwen FanDepartment of Respiratory Medicine, General Hospital of PLA Air Force, Beijing, China,
,
Bo LiuDepartment of Respiratory Medicine, General Hospital of PLA Air Force, Beijing, China, ;Graduate Student Ministry of Education, Hebei North University, Zhangjiakou, China,
,
Shuai ZhangDepartment of Respiratory Medicine, General Hospital of PLA Air Force, Beijing, China, ;Graduate Student Ministry of Education, Hebei North University, Zhangjiakou, China,
,
Huiguo LiuDepartment of Respiratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, and
,
Yang LiInstitute of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, China
,
Dong WangDepartment of Respiratory Medicine, General Hospital of PLA Air Force, Beijing, China,
,
Ying LiuDepartment of Respiratory Medicine, General Hospital of PLA Air Force, Beijing, China,
,
Jian LiDepartment of Respiratory Medicine, General Hospital of PLA Air Force, Beijing, China,
,
Ning WangDepartment of Respiratory Medicine, General Hospital of PLA Air Force, Beijing, China,
,
Yi LiuDepartment of Respiratory Medicine, General Hospital of PLA Air Force, Beijing, China,
&
Bo ZhangDepartment of Respiratory Medicine, General Hospital of PLA Air Force, Beijing, China, Correspondence[email protected]
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Pages 381-387 | Received 10 Jul 2014, Accepted 20 Oct 2014, Published online: 09 Apr 2015

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Bingbing Ye, Xiaofei Peng, Danyan Su, Dongli Liu, Yanyun Huang, Yuqin Huang & Yusheng Pang. (2022) Effects of YM155 on the proliferation and apoptosis of pulmonary artery smooth muscle cells in a rat model of high pulmonary blood flow-induced pulmonary arterial hypertension. Clinical and Experimental Hypertension 44:5, pages 470-479.
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Ahmad Beik, Hamid Najafipour, Siyavash Joukar, Soodeh Rajabi, Maryam Iranpour & Zeinab Kordestani. (2021) Perillyl alcohol suppresses monocrotaline-induced pulmonary arterial hypertension in rats via anti-remodeling, anti-oxidant, and anti-inflammatory effects. Clinical and Experimental Hypertension 43:3, pages 270-280.
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Articles from other publishers (14)

Isabel Blanco, Maribel Marquina, Olga Tura-Ceide, Elisabet Ferrer, Ana M. Ramírez, Manuel Lopez-Meseguer, Maria Callejo, Francisco Perez-Vizcaino, Victor Ivo Peinado & Joan Albert Barberà. (2023) Survivin inhibition with YM155 ameliorates experimental pulmonary arterial hypertension. Frontiers in Pharmacology 14.
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Guo Chen, Shuang Chen, Xingpeng Di, Shengyin He, Yugao Liu, Rui Qu, Yi Luo, Yuebai Liu & Luo Yang. (2022) Survivin knockdown alleviates pathological hydrostatic pressure-induced bladder smooth muscle cell dysfunction and BOO-induced bladder remodeling via autophagy. Frontiers in Cell and Developmental Biology 10.
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Rui Wang, Jingjing Xu, Jinbo Wu, Shunheng Gao & Zhiping Wang. (2021) Angiotensin‑converting enzyme 2 alleviates pulmonary artery hypertension through inhibition of focal adhesion kinase expression. Experimental and Therapeutic Medicine 22:4.
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Simin Yan, Thomas C. Resta & Nikki L. Jernigan. (2020) Vasoconstrictor Mechanisms in Chronic Hypoxia-Induced Pulmonary Hypertension: Role of Oxidant Signaling. Antioxidants 9:10, pages 999.
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Shanshan Song, Aleksandra Babicheva, Tengteng Zhao, Ramon J. Ayon, Marisela Rodriguez, Shamin Rahimi, Francesca Balistrieri, Angela Harrington, John Y.-J. Shyy, Patricia A. Thistlethwaite, Ayako Makino & Jason X.-J. Yuan. (2020) Notch enhances Ca 2+ entry by activating calcium-sensing receptors and inhibiting voltage-gated K + channels . American Journal of Physiology-Cell Physiology 318:5, pages C954-C968.
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Aleksandra Babicheva, Ramon J. Ayon, Tengteng Zhao, Jose F. Ek Vitorin, Nicole M. Pohl, Aya Yamamura, Hisao Yamamura, Brooke A. Quinton, Manqing Ba, Linda Wu, Keeley S. Ravellette, Shamin Rahimi, Francesca Balistrieri, Angela Harrington, Rebecca R. Vanderpool, Patricia A. Thistlethwaite, Ayako Makino & Jason X.-J. Yuan. (2020) MicroRNA-mediated downregulation of K + channels in pulmonary arterial hypertension . American Journal of Physiology-Lung Cellular and Molecular Physiology 318:1, pages L10-L26.
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Muhammed Fatih Dogan, Oguzhan Yildiz, Seyfullah Oktay Arslan & Kemal Gokhan Ulusoy. (2019) Potassium channels in vascular smooth muscle: a pathophysiological and pharmacological perspective. Fundamental & Clinical Pharmacology 33:5, pages 504-523.
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Djuro Kosanovic, Simon Maximilian Platzek, Aleksandar Petrovic, Akylbek Sydykov, Abdirashit Maripov, Argen Mamazhakypov, Meerim Sartmyrzaeva, Kubatbek Muratali Uulu, Meerim Cholponbaeva, Aidana Toktosunova, Nazgul Omurzakova, Melis Duishobaev, Christina Vroom, Oleg Pak, Norbert Weissmann, Hossein Ardeschir Ghofrani, Akpay Sarybaev & Ralph Theo Schermuly. (2019) Circulating Apoptotic Signals During Acute and Chronic Exposure to High Altitude in Kyrgyz Population. Frontiers in Physiology 10.
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Yorka Muñoz, Andrea C. Paula-Lima & Marco T. Núñez. (2018) Reactive oxygen species released from astrocytes treated with amyloid beta oligomers elicit neuronal calcium signals that decrease phospho-Ser727-STAT3 nuclear content. Free Radical Biology and Medicine 117, pages 132-144.
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G. Gravina, C. Wasén, M.J. Garcia-Bonete, M. Turkkila, M.C. Erlandsson, S. Töyrä Silfverswärd, M. Brisslert, R. Pullerits, K.M. Andersson, G. Katona & M.I. Bokarewa. (2017) Survivin in autoimmune diseases. Autoimmunity Reviews 16:8, pages 845-855.
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Olivier Boucherat, Geraldine Vitry, Isabelle Trinh, Roxane Paulin, Steeve Provencher & Sebastien Bonnet. (2017) The cancer theory of pulmonary arterial hypertension. Pulmonary Circulation 7:2, pages 285-299.
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Yasunobu Hayabuchi. (2016) The Action of Smooth Muscle Cell Potassium Channels in the Pathology of Pulmonary Arterial Hypertension. Pediatric Cardiology 38:1, pages 1-14.
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Yasunobu Hayabuchi. (2016) Potassium Channels in Pulmonary Arterial Hypertension. Pediatric Cardiology and Cardiac Surgery 32:3, pages 189-198.
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Olivier Boucherat, Sophie Chabot, Fabrice Antigny, Frédéric Perros, Steeve Provencher & Sébastien Bonnet. (2015) Potassium channels in pulmonary arterial hypertension. European Respiratory Journal 46:4, pages 1167-1177.
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