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Research Article

Silibinin induced-autophagic and apoptotic death is associated with an increase in reactive oxygen and nitrogen species in HeLa cells

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Pages 1307-1324 | Received 09 May 2011, Accepted 23 Aug 2011, Published online: 21 Oct 2011

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Read on this site (5)

Yang Yu, Lan-fang Li, Jing Tao, Xiao-mian Zhou & Cheng Xu. (2019) Silibinin induced apoptosis of human epidermal cancer A431 cells by promoting mitochondrial NOS. Free Radical Research 53:7, pages 714-726.
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Yang Yu, Si-Miao Fan, Yuan-Chao Ye, Shin-ichi Tashiro, Satoshi Onodera & Takashi Ikejima. (2012) The tyrphostin AG1478 augments oridonin-induced A431 cell apoptosis by blockage of JNK MAPK and enhancement of oxidative stress. Free Radical Research 46:11, pages 1393-1405.
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Yang Yu, Si Miao Fan, Su Juan Yuan, Shin-Ichi Tashiro, Satoshi Onodera & Takashi Ikejima. (2012) Nitric oxide (•NO) generation but not ROS plays a major role in silibinin-induced autophagic and apoptotic death in human epidermoid carcinoma A431 cells. Free Radical Research 46:11, pages 1346-1360.
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Linghe Zang, Hao He, Yuanchao Ye, Weiwei Liu, Simiao Fan, Shin-Ichi Tashiro, Satoshi Onodera & Takashi Ikejima. (2012) Nitric oxide augments oridonin-induced efferocytosis by human histocytic lymphoma U937 cells via autophagy and the NF-κB-COX-2-IL-1β pathway. Free Radical Research 46:10, pages 1207-1219.
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Simiao Fan, Yang Yu, Min Qi, Zhongdong Sun, Lihua Li, Guodong Yao, Shin-Ichi Tashiro, Satoshi Onodera & Takashi Ikejima. (2012) P53-mediated GSH depletion enhanced the cytotoxicity of NO in silibinin-treated human cervical carcinoma HeLa cells. Free Radical Research 46:9, pages 1082-1092.
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