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Review Article

Regulation of DNA glycosylases and their role in limiting disease

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Pages 460-478 | Received 15 Nov 2011, Accepted 05 Jan 2012, Published online: 06 Feb 2012

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Marcus S. Cooke. (2012) Special issue on DNA oxidation: Mechanisms, measurement and consequences. Free Radical Research 46:4, pages 365-366.
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L. Tanner, A. B. Single, R. K. V. Bhongir, M. Heusel, T. Mohanty, C. A. Q. Karlsson, L. Pan, C-M. Clausson, J. Bergwik, K. Wang, C. K. Andersson, R. M. Oommen, J. S. Erjefält, J. Malmström, O. Wallner, I. Boldogh, T. Helleday, C. Kalderén & A. Egesten. (2023) Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis in a murine lung fibrosis model. Nature Communications 14:1.
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Alexandra N. Karmanova, Nikita A. Nikulin & Andrei A. Zimin. (2022) Structural organization, evolution, and distribution of viral pyrimidine dimer-DNA glycosylases. Biophysical Reviews 14:4, pages 923-932.
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Sai Santosh Babu Komakula, Bhavya Blaze, Hong Ye, Agnieszka Dobrzyn & Harini Sampath. (2021) A Novel Role for the DNA Repair Enzyme 8-Oxoguanine DNA Glycosylase in Adipogenesis. International Journal of Molecular Sciences 22:3, pages 1152.
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Fabienne Hans, Muge Senarisoy, Chandini Bhaskar Naidu & Joanna Timmins. (2020) Focus on DNA Glycosylases—A Set of Tightly Regulated Enzymes with a High Potential as Anticancer Drug Targets. International Journal of Molecular Sciences 21:23, pages 9226.
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Ostiane D’Augustin, Sébastien Huet, Anna Campalans & Juan Pablo Radicella. (2020) Lost in the Crowd: How Does Human 8-Oxoguanine DNA Glycosylase 1 (OGG1) Find 8-Oxoguanine in the Genome?. International Journal of Molecular Sciences 21:21, pages 8360.
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Rajwinder Kaur, Dylan J. Nikkel & Stacey D. Wetmore. (2020) Computational studies of DNA repair: Insights into the function of monofunctional DNA glycosylases in the base excision repair pathway. WIREs Computational Molecular Science 10:5.
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Mrinal Srivastava, Dan Su, Huimin Zhang, Zhen Chen, Mengfan Tang, Litong Nie & Junjie Chen. (2020) HMCES safeguards replication from oxidative stress and ensures error‐free repair . EMBO reports 21:6.
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Irina G. Minko, Vladimir L. Vartanian, Naoto N. Tozaki, Erdem Coskun, Sanem Hosbas Coskun, Pawel Jaruga, Jongchan Yeo, Sheila S. David, Michael P. Stone, Martin Egli, Miral Dizdaroglu, Amanda K. McCullough & R. Stephen Lloyd. (2020) Recognition of DNA adducts by edited and unedited forms of DNA glycosylase NEIL1. DNA Repair 85, pages 102741.
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William A. BeardJulie K. HortonRajendra PrasadSamuel H. Wilson. (2019) Eukaryotic Base Excision Repair: New Approaches Shine Light on Mechanism. Annual Review of Biochemistry 88:1, pages 137-162.
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Priyanka Sharma & Harini Sampath. (2019) Mitochondrial DNA Integrity: Role in Health and Disease. Cells 8:2, pages 100.
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Sai Santosh Babu Komakula, Jana Tumova, Deeptha Kumaraswamy, Natalie Burchat, Vladimir Vartanian, Hong Ye, Agnieszka Dobrzyn, R. Stephen Lloyd & Harini Sampath. (2018) The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue. Scientific Reports 8:1.
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Vladimir Vartanian, Jana Tumova, Pawel Dobrzyn, Agnieszka Dobrzyn, Yusaku Nakabeppu, R. Stephen Lloyd & Harini Sampath. (2017) 8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle. PLOS ONE 12:7, pages e0181687.
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Ki Cheon Kim, Madduma Hewage Susara Ruwan Kumara, Kyoung Ah Kang, Mei Jing Piao, Min Chang Oh, Yea Seong Ryu, Jin Oh Jo, Young Sun Mok, Jennifer H. Shin, Yeunsoo Park, Seong Bong Kim, Suk Jae Yoo & Jin Won Hyun. (2017) Exposure of keratinocytes to non-thermal dielectric barrier discharge plasma increases the level of 8-oxoguanine via inhibition of its repair enzyme. Molecular Medicine Reports 16:5, pages 6870-6875.
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K. B. Gutzkow, N. Duale, T. Danielsen, H. von Stedingk, S. Shahzadi, C. Instanes, A.-K. Olsen, I.-L. Steffensen, T. Hofer, M. Törnqvist, G. Brunborg & B. Lindeman. (2016) Enhanced susceptibility of obese mice to glycidamide-induced sperm chromatin damage without increased oxidative stress. Andrology 4:6, pages 1102-1114.
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Aishwarya Prakash, Vy Bao Cao & Sylvie Doublié. (2016) Phosphorylation Sites Identified in the NEIL1 DNA Glycosylase Are Potential Targets for the JNK1 Kinase. PLOS ONE 11:8, pages e0157860.
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Vinodkumar B. PillaiSamik BinduWill Sharp, Yong Hu Fang, Gene Kim, Madhu Gupta, Sadhana SamantMahesh P. Gupta. (2016) Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice. American Journal of Physiology-Heart and Circulatory Physiology 310:8, pages H962-H972.
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Prasad T. Reddy, Pawel Jaruga, Bryant C. Nelson, Mark S. Lowenthal, Ann-Sofie Jemth, Olga Loseva, Erdem Coskun, Thomas Helleday & Miral Dizdaroglu. 2016. Isotope Labeling of Biomolecules - Applications. Isotope Labeling of Biomolecules - Applications 305 332 .
Miral Dizdaroglu. (2015) Oxidatively induced DNA damage and its repair in cancer. Mutation Research/Reviews in Mutation Research 763, pages 212-245.
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B. M. Brenerman, J. L. Illuzzi & D. M. Wilson. (2014) Base excision repair capacity in informing healthspan. Carcinogenesis 35:12, pages 2643-2652.
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Harini Sampath. (2014) Oxidative DNA damage in disease-Insights gained from base excision repair glycosylase-deficient mouse models. Environmental and Molecular Mutagenesis 55:9, pages 689-703.
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Susan S. Wallace. (2014) Base excision repair: A critical player in many games. DNA Repair 19, pages 14-26.
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Mengxia LiDavid M. WilsonIIIIII. (2014) Human Apurinic/Apyrimidinic Endonuclease 1. Antioxidants & Redox Signaling 20:4, pages 678-707.
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Aishwarya Prakash, Brittany L. Carroll, Joann B. Sweasy, Susan S. Wallace & Sylvie Doublié. (2014) Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: Activity, structure, and the effect of editing. DNA Repair 14, pages 17-26.
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Gabriella Cavallini, Alessio Donati, Biagio Capasso, Michele Fella, Vincenzo Leone, Gaetano Pezzella, Giorgio Cosimo Romano, Angelo Vagali & Ettore Bergamini. (2013) Effects of stimulation of autophagy on the urinary excretion of biomarkers of the oxidative status. Aging Clinical and Experimental Research 26:1, pages 13-18.
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Aaron C. Jacobs, Marcus J. Calkins, Ajit Jadhav, Dorjbal Dorjsuren, David Maloney, Anton Simeonov, Pawel Jaruga, Miral Dizdaroglu, Amanda K. McCullough & R. Stephen Lloyd. (2013) Inhibition of DNA Glycosylases via Small Molecule Purine Analogs. PLoS ONE 8:12, pages e81667.
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Vasily V. Grinev, Tatsiana V. Ramanouskaya & Sergey V. Gloushen. (2013) Multidimensional control of cell structural robustness. Cell Biology International 37:10, pages 1023-1037.
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Harini Sampath, Vladimir Vartanian, M. Rick Rollins, Kunihiko Sakumi, Yusaku Nakabeppu & R. Stephen Lloyd. (2012) 8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Increases Susceptibility to Obesity and Metabolic Dysfunction. PLoS ONE 7:12, pages e51697.
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Dora Il'yasova, Peter Scarbrough & Ivan Spasojevic. (2012) Urinary biomarkers of oxidative status. Clinica Chimica Acta 413:19-20, pages 1446-1453.
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