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José Teixeira, Catarina Oliveira, Fernando Cagide, Ricardo Amorim, Jorge Garrido, Fernanda Borges & Paulo J. Oliveira. (2018) Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 567-576.
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Ana I. Duarte, Izabela Sadowska-Bartosz, Agnieszka Karkucinska-Wieckowska, Magdalena Lebiedzinska-Arciszewska, Carlos M. Palmeira, Anabela P. Rolo, Yaschar Kabiri, Barbara Zavan, Paolo Pinton, Fernanda Borges, Hans Zischka, John G. Jones, Grzegorz Bartosz, Paulo J. Oliveira & Mariusz R. Wieckowski. 2023. Aging. Aging
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Yang Zhang, Juntao Wang, Shuwen Lei, Yixin Hu & Lei Fu. (2022) Utilization of mitochondrial-targeted small molecules in protecting stored platelets against storage lesions. European Journal of Medicinal Chemistry Reports 6, pages 100070.
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Cláudia M. Deus, José Teixeira, Nuno Raimundo, Paolo Tucci, Fernanda Borges, Luciano Saso & Paulo J. Oliveira. (2022) Modulation of cellular redox environment as a novel therapeutic strategy for Parkinson's disease. European Journal of Clinical Investigation 52:10.
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Carlos Fernandes, Fernando Cagide, Jorge Simões, Carlos Pita, Eurico Pereira, Afonso J. C. Videira, Pedro Soares, José F. S. Duarte, António M. S. Santos, Paulo J. Oliveira, Fernanda Borges & Filomena S. G. Silva. (2022) Targeting Hydroxybenzoic Acids to Mitochondria as a Strategy to Delay Skin Ageing: An In Vitro Approach. Molecules 27:19, pages 6183.
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Dominik Arbon, Kateřina Ženíšková, Karolína Šubrtová, Jan Mach, Jan Štursa, Marta Machado, Farnaz Zahedifard, Tereza Leštinová, Carolina Hierro-Yap, Jiri Neuzil, Petr Volf, Markus Ganter, Martin Zoltner, Alena Zíková, Lukáš Werner & Robert Sutak. (2022) Repurposing of MitoTam: Novel Anti-Cancer Drug Candidate Exhibits Potent Activity against Major Protozoan and Fungal Pathogens. Antimicrobial Agents and Chemotherapy 66:8.
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Elianne P. Bulthuis, Claudia Einer, Felix Distelmaier, Laszlo Groh, Sjenet E. van Emst - de Vries, Els van de Westerlo, Melissa van de Wal, Jori Wagenaars, Richard J. Rodenburg, Jan A.M. Smeitink, Niels P. Riksen, Peter H.G.M. Willems, Merel J.W. Adjobo-Hermans, Hans Zischka & Werner J.H. Koopman. (2022) The decylTPP mitochondria-targeting moiety lowers electron transport chain supercomplex levels in primary human skin fibroblasts. Free Radical Biology and Medicine 188, pages 434-446.
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Mariana Castelôa, Beatriz Moreira-Pinto, Sofia Benfeito, Fernanda Borges, Bruno M. Fonseca & Irene Rebelo. (2022) In Vitro Effects of Mitochondria-Targeted Antioxidants in a Small-Cell Carcinoma of the Ovary of Hypercalcemic Type and in Type 1 and Type 2 Endometrial Cancer. Biomedicines 10:4, pages 800.
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Carlos Fernandes, Afonso J. C. Videira, Caroline D. Veloso, Sofia Benfeito, Pedro Soares, João D. Martins, Beatriz Gonçalves, José F. S. Duarte, António M. S. Santos, Paulo J. Oliveira, Fernanda Borges, José Teixeira & Filomena S. G. Silva. (2021) Cytotoxicity and Mitochondrial Effects of Phenolic and Quinone-Based Mitochondria-Targeted and Untargeted Antioxidants on Human Neuronal and Hepatic Cell Lines: A Comparative Analysis. Biomolecules 11:11, pages 1605.
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Daniel Chavarria, Ophelie Da Silva, Sofia Benfeito, Sandra Barreiro, Jorge Garrido, Fernando Cagide, Pedro Soares, Fernando Remião, Xavier Brazzolotto, Florian Nachon, Paulo J. Oliveira, José Dias & Fernanda Borges. (2021) Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases. Antioxidants 10:2, pages 329.
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Merly de Armas-Ricard, Enrique Ruiz-Reyes & Oney Ramírez-Rodríguez. (2019) Caffeates and Caffeamides: Synthetic Methodologies and Their Antioxidant Properties. International Journal of Medicinal Chemistry 2019, pages 1-15.
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Lucia Biasutto, Andrea Mattarei, Martina La Spina, Michele Azzolini, Sofia Parrasia, Ildikò Szabò & Mario Zoratti. (2019) Strategies to target bioactive molecules to subcellular compartments. Focus on natural compounds. European Journal of Medicinal Chemistry 181, pages 111557.
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Nirmala Koju, Abdoh Taleb, Jifang Zhou, Ge Lv, Jie Yang, Xian Cao, Hui Lei & Qilong Ding. (2019) Pharmacological strategies to lower crosstalk between nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and mitochondria. Biomedicine & Pharmacotherapy 111, pages 1478-1498.
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Manuel Fuentes, Ramiro Araya-Maturana, Iván Palomo & Eduardo Fuentes. (2018) Platelet mitochondrial dysfunction and mitochondria-targeted quinone-and hydroquinone-derivatives: Review on new strategy of antiplatelet activity. Biochemical Pharmacology 156, pages 215-222.
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Andrey Voronkov & Dmitry Pozdnyakov. (2018) Endothelotropic Activity of 4-Hydroxy-3,5-Di-Tret-Butylcinnamic Acid in the Conditions of Experimental Cerebral Ischemia. Research Results in Pharmacology 4:2, pages 1-10.
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José A. Ribeiro, Sofia Benfeito, Fernando Cagide, José Teixeira, Paulo J. Oliveira, Fernanda Borges, António F. Silva & Carlos M. Pereira. (2018) Electrochemical Behavior of a Mitochondria-Targeted Antioxidant at an Interface between Two Immiscible Electrolyte Solutions: An Alternative Approach to Study Lipophilicity. Analytical Chemistry 90:13, pages 7989-7996.
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Catarina Oliveira, Fernando Cagide, José Teixeira, Ricardo Amorim, Lisa Sequeira, Francesco Mesiti, Tiago Silva, Jorge Garrido, Fernando Remião, Santiago Vilar, Eugenio Uriarte, Paulo J. Oliveira & Fernanda Borges. (2018) Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors. Frontiers in Chemistry 6.
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José Teixeira, Cláudia M. Deus, Fernanda Borges & Paulo J. Oliveira. (2018) Mitochondria: Targeting mitochondrial reactive oxygen species with mitochondriotropic polyphenolic-based antioxidants. The International Journal of Biochemistry & Cell Biology 97, pages 98-103.
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José Teixeira, Ricardo Amorim, Katia Santos, Pedro Soares, Sandipan Datta, Gino A. Cortopassi, Teresa L. Serafim, Vilma A. Sardão, Jorge Garrido, Fernanda Borges & Paulo J. Oliveira. (2018) Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative. Toxicology 393, pages 123-139.
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Ricardo Amorim, Sofia Benfeito, José Teixeira, Fernando Cagide, Paulo J. Oliveira & Fernanda Borges. 2018. Mitochondrial Biology and Experimental Therapeutics. Mitochondrial Biology and Experimental Therapeutics
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José Teixeira, Catarina Oliveira, Ricardo Amorim, Fernando Cagide, Jorge Garrido, José A. Ribeiro, Carlos M. Pereira, António F. Silva, Paula B. Andrade, Paulo J. Oliveira & Fernanda Borges. (2017) Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondria. Scientific Reports 7:1.
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Abdulsalam A.M. Alkhaldi, Jan Martinek, Brian Panicucci, Christophe Dardonville, Alena Zíková & Harry P. de Koning. (2016) Trypanocidal action of bisphosphonium salts through a mitochondrial target in bloodstream form Trypanosoma brucei. International Journal for Parasitology: Drugs and Drug Resistance 6:1, pages 23-34.
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Daniel Chavarria, Tiago Silva, Daniel Martins, Joana Bravo, Teresa Summavielle, Jorge Garrido & Fernanda Borges. (2015) Exploring cinnamic acid scaffold: development of promising neuroprotective lipophilic antioxidants. MedChemComm 6:6, pages 1043-1053.
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José Teixeira, Pedro Soares, Sofia Benfeito, Michael P. Murphy, Paulo J. Oliveira & Fernanda Borges. 2015. Mitochondrial Medicine. Mitochondrial Medicine
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Brian D. Fink, Judith A. Herlein, Deng Fu Guo, Chaitanya Kulkarni, Benjamin J. Weidemann, Liping Yu, Justin L. Grobe, Kamal Rahmouni, Robert J. Kerns & William I. Sivitz. (2014) A Mitochondrial-Targeted Coenzyme Q Analog Prevents Weight Gain and Ameliorates Hepatic Dysfunction in High-Fat–Fed Mice. Journal of Pharmacology and Experimental Therapeutics 351:3, pages 699-708.
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Sofia Benfeito, Catarina Oliveira, Pedro Soares, Carlos Fernandes, Tiago Silva, José Teixeira & Fernanda Borges. (2013) Antioxidant therapy: Still in search of the ‘magic bullet’. Mitochondrion 13:5, pages 427-435.
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M.W. Anders. (2013) Exploiting endobiotic metabolic pathways to target xenobiotic antioxidants to mitochondria. Mitochondrion 13:5, pages 454-463.
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José Teixeira, Tiago Silva, Sofia Benfeito, Alexandra Gaspar, E. Manuela Garrido, Jorge Garrido & Fernanda Borges. (2013) Exploring nature profits: Development of novel and potent lipophilic antioxidants based on galloyl–cinnamic hybrids. European Journal of Medicinal Chemistry 62, pages 289-296.
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Frederick A VillamenaAmlan Das & Kevin M Nash. (2012) Potential implication of the chemical properties and bioactivity of nitrone spin traps for therapeutics. Future Medicinal Chemistry 4:9, pages 1171-1207.
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