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Research Article

Protective effect of Homer 1a against hydrogen peroxide-induced oxidative stress in PC12 cells

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Pages 766-776 | Received 10 Dec 2011, Accepted 19 Mar 2012, Published online: 10 Apr 2012

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Eui-Baek Byun, Woo-Young Park, Woo Sik Kim, Ha-Yeon Song, Nak-Yun Sung & Eui-Hong Byun. (2018) Neuroprotective effect of Capsicum annuum var. abbreviatum against hydrogen peroxide-induced oxidative stress in HT22 hippocampus cells. Bioscience, Biotechnology, and Biochemistry 82:12, pages 2149-2157.
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Articles from other publishers (39)

Xiu-Quan Wu, Ning Su, Zhou Fei & Fei Fei. (2022) Homer signaling pathways as effective therapeutic targets for ischemic and traumatic brain injuries and retinal lesions. Neural Regeneration Research 17:7, pages 1454.
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Ying Tang, Yingqin Li, Guangyin Yu, Zemin Ling, Ke Zhong, Prince L. M. Zilundu, Wenfu Li, Rao Fu & Li-Hua Zhou. (2020) MicroRNA-137-3p Protects PC12 Cells Against Oxidative Stress by Downregulation of Calpain-2 and nNOS. Cellular and Molecular Neurobiology 41:6, pages 1373-1387.
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Hironao Nakayama, Masako Nakahara, Erina Matsugi, Midori Soda, Tomoka Hattori, Koki Hara, Ayuki Usami, Chiaki Kusumoto, Shigeki Higashiyama & Kiyoyuki Kitaichi. (2020) Protective Effect of Ferulic Acid against Hydrogen Peroxide Induced Apoptosis in PC12 Cells. Molecules 26:1, pages 90.
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Li-Min Zhang, Rong-Rong Zhen, Chao Gu, Tian-Li Zhang, Yue Li, Miao Jin, Bing Hu & Hong-Mei An. (2020) RETRACTED ARTICLE: Chinese medicine Di-Huang-Yi-Zhi protects PC12 cells from H2O2-induced apoptosis by regulating ROS-ASK1-JNK/p38 MAPK signaling. BMC Complementary Medicine and Therapies 20:1.
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Tao Chen, Jie Zhu, Yu-Hai Wang & Chun-Hua Hang. (2020) Arc silence aggravates traumatic neuronal injury via mGluR1-mediated ER stress and necroptosis. Cell Death & Disease 11:1.
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Lin Huang, Weiwei Jiang, Lijuan Zhu, Chaoyang Ma, Zhaoping Ou, Chenxi Luo, Jing Wu, Lixin Wen, Zhuliang Tan & Jine Yi. (2020) γ-Oryzanol suppresses cell apoptosis by inhibiting reactive oxygen species-mediated mitochondrial signaling pathway in H2O2-stimulated L02 cells. Biomedicine & Pharmacotherapy 121, pages 109554.
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Yang Niu, Xiang Xia, PeiWen Song, Huang Fang, FuLong Dong, Hui Tao, Chao Yang & CaiLiang Shen. (2019) Bone mesenchymal stem cell‐conditioned medium attenuates the effect of oxidative stress injury on NSCs by inhibiting the Notch1 signaling pathway. Cell Biology International 43:11, pages 1267-1275.
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Jialiang Wei, Xiuquan Wu, Peng Luo, Kangyi Yue, Yang Yu, Jingnan Pu, Lei Zhang, Shuhui Dai, Donghui Han & Zhou Fei. (2019) Homer1a Attenuates Endoplasmic Reticulum Stress-Induced Mitochondrial Stress After Ischemic Reperfusion Injury by Inhibiting the PERK Pathway. Frontiers in Cellular Neuroscience 13.
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Hua Li, Xuhui Li, Wei Luo & Xiaolong Zhu. (2019) (Z)-7,4′-Dimethoxy-6-hydroxy-aurone-4-O-β-glucopyranoside exerts neuroprotective effects in vitro and anxiolytic activity in vivo. NeuroReport 30:4, pages 280-287.
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Jie Yang, Tingting Huo, Xu Zhang, Jie Ma, Yulin Wang, Faqin Dong & Jianjun Deng. (2017) Oxidative stress and cell cycle arrest induced by short-term exposure to dustfall PM2.5 in A549 cells. Environmental Science and Pollution Research 25:23, pages 22408-22419.
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Jingjing Jia, Ting Zhang, Jieshan Chi, Xiaoma Liu, Jingjing Sun, Qizhi Xie, Sijia Peng, Changyan Li & Li Yi. (2018) Neuroprotective Effect of CeO2@PAA-LXW7 Against H2O2-Induced Cytotoxicity in NGF-Differentiated PC12 Cells. Neurochemical Research 43:7, pages 1439-1453.
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Xiuquan Wu, Peng Luo, Wei Rao, Shuhui Dai, Lei Zhang, Wenke Ma, Jingnan Pu, Yang Yu, Jiu Wang & Zhou Fei. (2018) Homer1a Attenuates Hydrogen Peroxide-Induced Oxidative Damage in HT-22 Cells through AMPK-Dependent Autophagy. Frontiers in Neuroscience 12.
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Dong-Yang Chen, Fan Yang & Yu-Qun Lin. (2016) Neuroprotective constituent from the seeds of Alpinia katsumadai Hayata. Phytochemistry Letters 18, pages 59-63.
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Wei Rao, Cheng Peng, Lei Zhang, Ning Su, Kai Wang, Hao Hui, Shu-hui Dai, Yue-fan Yang, Peng Luo & Zhou Fei. (2016) Homer1a attenuates glutamate-induced oxidative injury in HT-22 cells through regulation of store-operated calcium entry. Scientific Reports 6:1.
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Chong-Un Cheong, Ching-Sheng Yeh, Yi-Wen Hsieh, Ying-Ray Lee, Mei-Ying Lin, Chung-Yi Chen & Chien-Hsing Lee. (2016) Protective Effects of Costunolide against Hydrogen Peroxide-Induced Injury in PC12 Cells. Molecules 21:7, pages 898.
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Jin Huang, Chi Zhou, Jun He, Zheng Hu, Wen-chao Guan & Sheng-hong Liu. (2016) Protective effect of reduced glutathione C60 derivative against hydrogen peroxide-induced apoptosis in HEK 293T cells. Journal of Huazhong University of Science and Technology [Medical Sciences] 36:3, pages 356-363.
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Dexin Kong, Yantao Han, Chunbo Wang, Xuehong Chen, Qixiao Jiang, Qiaoyun Wang & Zhiwu Han. (2016) Cytoprotective Effects of Oleanolic Acid in Human Umbilical Vascular Endothelial Cells is Mediated Via UCP2/ROS/Cytochrome C/AIF Pathway. Journal of Cardiovascular Pharmacology 67:4, pages 344-350.
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Silvia Fossati, Patrizia Giannoni, Maria E. Solesio, Sarah L. Cocklin, Erwin Cabrera, Jorge Ghiso & Agueda Rostagno. (2016) The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain. Neurobiology of Disease 86, pages 29-40.
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Fei Fei, Juan Li, Wei Rao, Wenbo Liu, Xiaoyan Chen, Ning Su, Yusheng Wang & Zhou Fei. (2015) Upregulation of Homer1a Promoted Retinal Ganglion Cell Survival After Retinal Ischemia and Reperfusion via Interacting with Erk Pathway. Cellular and Molecular Neurobiology 35:7, pages 1039-1048.
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Y Wang, W Rao, C Zhang, C Zhang, M-d Liu, F Han, L-b Yao, H Han, P Luo, N Su & Z Fei. (2015) Scaffolding protein Homer1a protects against NMDA-induced neuronal injury. Cell Death & Disease 6:8, pages e1843-e1843.
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Yan-Zhi Wu, Fang Qiao, Guo-Wei Xu, Jie Zhao, Jun-Fang Teng, Chun Li & Wen-Jing Deng. (2015) Neuroprotective metabolites from the endophytic fungus Penicillium citrinum of the mangrove Bruguiera gymnorrhiza. Phytochemistry Letters 12, pages 148-152.
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Dong-Feng Guan, Peng-Yu Ren, Wei Hu & Yue-Lin Zhang. (2014) The mGluR5 Positive Allosteric Modulator CDPPB Inhibits SO2-Induced Protein Radical Formation and Mitochondrial Dysfunction Through Activation of Akt in Mouse Hippocampal HT22 Cells. Cellular and Molecular Neurobiology 35:4, pages 573-583.
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FENGSHAN XIE, WEIWEI CAI, YANLING LIU, YUE LI, BIN DU, LEI FENG & LIYING QIU. (2015) Vaccarin attenuates the human EA.hy926 endothelial cell oxidative stress injury through inhibition of Notch signaling. International Journal of Molecular Medicine 35:1, pages 135-142.
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Shu-Hui Dai, Tao Chen, Yu-Hai Wang, Jie Zhu, Peng Luo, Wei Rao, Yue-Fan Yang, Zhou Fei & Xiao-Fan Jiang. (2014) Sirt3 Protects Cortical Neurons against Oxidative Stress via Regulating Mitochondrial Ca2+ and Mitochondrial Biogenesis. International Journal of Molecular Sciences 15:8, pages 14591-14609.
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Miao-Miao Lv, Yong-Chun Cheng, Zhi-Bin Xiao, Mei-Yan Sun, Peng-Cheng Ren & Xu-De Sun. (2014) Down-regulation of Homer1b/c attenuates group I metabotropic glutamate receptors dependent Ca2+ signaling through regulating endoplasmic reticulum Ca2+ release in PC12 cells. Biochemical and Biophysical Research Communications 450:4, pages 1568-1574.
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Ben Ru Xin, Jian Fang Liu, Jie Kang & Wing Ping Chan. (2014) (2R, 3S)-pinobanksin-3-cinnamate, a new flavonone from seeds of Alpinia galanga willd., presents in vitro neuroprotective effects. Molecular & Cellular Toxicology 10:2, pages 165-172.
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F. Fei, W. Rao, L. Zhang, B.-G. Chen, J. Li, Z. Fei & Z. Chen. (2014) Downregulation of Homer1b/c improves neuronal survival after traumatic neuronal injury. Neuroscience 267, pages 187-194.
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P Luo, T Chen, Y Zhao, L Zhang, Y Yang, W Liu, S Li, W Rao, S Dai, J Yang & Z Fei. (2014) Postsynaptic scaffold protein Homer 1a protects against traumatic brain injury via regulating group I metabotropic glutamate receptors. Cell Death & Disease 5:4, pages e1174-e1174.
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Xia Li, Wei Chen, Lei Zhang, Wen-bo Liu & Zhou Fei. (2013) Inhibition of Store-Operated Calcium Entry Attenuates MPP+-Induced Oxidative Stress via Preservation of Mitochondrial Function in PC12 Cells: Involvement of Homer1a. PLoS ONE 8:12, pages e83638.
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Peng Luo, Yuefan Yang, Wei Liu, Wei Rao, Huan Bian, Xin Li, Tao Chen, Mengdong Liu, Yongbo Zhao, Shuhui Dai, Xu Yan & Zhou Fei. (2013) Downregulation of postsynaptic density-95-interacting regulator of spine morphogenesis reduces glutamate-induced excitotoxicity by differentially regulating glutamate receptors in rat cortical neurons. FEBS Journal 280:23, pages 6114-6127.
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Tao Chen, Yue-fan Yang, Peng Luo, Wei Liu, Shu-hui Dai, Xin-rui Zheng, Zhou Fei & Xiao-fan Jiang. (2013) Homer1 knockdown protects dopamine neurons through regulating calcium homeostasis in an in vitro model of Parkinson's disease. Cellular Signalling 25:12, pages 2863-2870.
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Wei Rao, Lei Zhang, Ning Su, Kai Wang, Hao Hui, Li Wang, Tao Chen, Peng Luo, Yue-fan Yang, Zao-bin Liu & Zhou Fei. (2013) Blockade of SOCE protects HT22 cells from hydrogen peroxide-induced apoptosis. Biochemical and Biophysical Research Communications 441:2, pages 351-356.
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Carmelina Chiarello, Elena Bortoloso, Andrea Carpi, Sandra Furlan & Pompeo Volpe. (2013) Negative feedback regulation of Homer 1a on norepinephrine-dependent cardiac hypertrophy. Experimental Cell Research 319:12, pages 1804-1814.
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Weixun Duan, Yang Yang, Wei Yi, Juanjuan Yan, Zhenxin Liang, Ning Wang, Yue Li, Wensheng Chen, Shiqiang Yu, Zhenxiao Jin & Dinghua Yi. (2013) New Role of JAK2/STAT3 Signaling in Endothelial Cell Oxidative Stress Injury and Protective Effect of Melatonin. PLoS ONE 8:3, pages e57941.
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Yang Yang, Weixun Duan, Zhenxin Liang, Wei Yi, Juanjuan Yan, Ning Wang, Yue Li, Wensheng Chen, Shiqiang Yu, Zhenxiao Jin & Dinghua Yi. (2013) Curcumin attenuates endothelial cell oxidative stress injury through Notch signaling inhibition. Cellular Signalling 25:3, pages 615-629.
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Ravichandran Srividhya & Periandavan Kalaiselvi. (2012) Neuroprotective potential of epigallo catechin-3-gallate in PC-12 cells. Neurochemical Research 38:3, pages 486-493.
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Yongbo Zhao, Peng Luo, Qindong Guo, Sanzhong Li, Lei Zhang, Mingming Zhao, Haoxiang Xu, Yuefan Yang, Waisang Poon & Zhou Fei. (2012) Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo. Experimental Neurology 237:2, pages 489-498.
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Peng Luo, Yongbo Zhao, Dong Li, Tao Chen, Sanzhong Li, Xiaodong Chao, Wenbo Liu, Lei Zhang, Yan Qu, Xiaofan Jiang, Gang Lu, Waisang Poon & Zhou Fei. (2012) Protective effect of Homer 1a on tumor necrosis factor-α with cycloheximide-induced apoptosis is mediated by mitogen-activated protein kinase pathways. Apoptosis 17:9, pages 975-988.
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