Advanced search
Publication Cover
Free Radical Research Volume 46, 2012 - Issue 11
Submit an article Journal homepage
236
Views
33
CrossRef citations to date
0
Altmetric
Research Article

In vitro antioxidant capacity and antigenotoxic properties of protoporphyrin and structurally related tetrapyrroles

Christine MölzerDepartment of Nutritional Sciences, Emerging Field Oxidative Stress and DNA Stability, Faculty of Life Sciences, University of Vienna, Vienna, Austria
,
Hedwig HuberDepartment of Nutritional Sciences, Emerging Field Oxidative Stress and DNA Stability, Faculty of Life Sciences, University of Vienna, Vienna, Austria
,
Andrea SteyrerDepartment of Nutritional Sciences, Emerging Field Oxidative Stress and DNA Stability, Faculty of Life Sciences, University of Vienna, Vienna, Austria
,
Gesa ZieselDepartment of Nutritional Sciences, Emerging Field Oxidative Stress and DNA Stability, Faculty of Life Sciences, University of Vienna, Vienna, Austria
,
Anita ErtlDepartment of Nutritional Sciences, Emerging Field Oxidative Stress and DNA Stability, Faculty of Life Sciences, University of Vienna, Vienna, Austria
,
Admira PlavoticDepartment of Nutritional Sciences, Emerging Field Oxidative Stress and DNA Stability, Faculty of Life Sciences, University of Vienna, Vienna, Austria
,
Marlies WallnerDepartment of Nutritional Sciences, Emerging Field Oxidative Stress and DNA Stability, Faculty of Life Sciences, University of Vienna, Vienna, Austria
,
Andrew Cameron BulmerHeart Foundation Research Centre, Griffith Health Institute, Griffith University (Gold Coast Campus), Southport QLD, Australia
&
Karl-Heinz WagnerDepartment of Nutritional Sciences, Emerging Field Oxidative Stress and DNA Stability, Faculty of Life Sciences, University of Vienna, Vienna, Austria;Heart Foundation Research Centre, Griffith Health Institute, Griffith University (Gold Coast Campus), Southport QLD, AustraliaCorrespondence[email protected]
 show all
Pages 1369-1377 | Received 01 Mar 2012, Accepted 19 Jul 2012, Published online: 17 Sep 2012

Citations (33)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Jana Novotná, Iryna Goncharova & Marie Urbanová. (2014) Guanosine assemblies: newly used matrices for chiroptical studies on biliverdin. Supramolecular Chemistry 26:1, pages 7-14.
Read now

Articles from other publishers (32)

Agnes Draxler, Amelie Blaschke, Jessica Binar, Maria Weber, Michael Haslacher, Viktoria Bartak, Laura Bragagna, George Mare, Lina Maqboul, Rebecca Klapp, Theresa Herzog, Marton Széll, Agnese Petrera, Brenda Laky, Karl-Heinz Wagner & Rainer Thell. (2023) Age-related influence on DNA damage, proteomic inflammatory markers and oxidative stress in hospitalized COVID-19 patients compared to healthy controls. Redox Biology 67, pages 102914.
Crossref
Alessandro Allegra, Santino Caserta, Sara Genovese, Giovanni Pioggia & Sebastiano Gangemi. (2023) Gender Differences in Oxidative Stress in Relation to Cancer Susceptibility and Survival. Antioxidants 12:6, pages 1255.
Crossref
Nathan C. Charlton, Maxim Mastyugin, Béla Török & Marianna Török. (2023) Structural Features of Small Molecule Antioxidants and Strategic Modifications to Improve Potential Bioactivity. Molecules 28:3, pages 1057.
Crossref
Bo Hee Choi, Mi-Ri Kim, Yu Na Jung, Smee Kang & Jungil Hong. (2022) Interfering with Color Response by Porphyrin-Related Compounds in the MTT Tetrazolium-Based Colorimetric Assay. International Journal of Molecular Sciences 24:1, pages 562.
Crossref
Libor Vítek. 2022. Carbon Monoxide in Drug Discovery. Carbon Monoxide in Drug Discovery 175 194 .
Nazlisadat Seyed Khoei, Karl-Heinz Wagner, Robert Carreras-Torres, Marc J. Gunter, Neil Murphy & Heinz Freisling. (2021) Associations between Prediagnostic Circulating Bilirubin Levels and Risk of Gastrointestinal Cancers in the UK Biobank. Cancers 13:11, pages 2749.
Crossref
Nazlisadat Seyed Khoei, Mazda Jenab, Neil Murphy, Barbara L. Banbury, Robert Carreras-Torres, Vivian Viallon, Tilman Kühn, Bas Bueno-de-Mesquita, Krasimira Aleksandrova, Amanda J. Cross, Elisabete Weiderpass, Magdalena Stepien, Andrew Bulmer, Anne Tjønneland, Marie-Christine Boutron-Ruault, Gianluca Severi, Franck Carbonnel, Verena Katzke, Heiner Boeing, Manuela M. Bergmann, Antonia Trichopoulou, Anna Karakatsani, Georgia Martimianaki, Domenico Palli, Giovanna Tagliabue, Salvatore Panico, Rosario Tumino, Carlotta Sacerdote, Guri Skeie, Susana Merino, Catalina Bonet, Miguel Rodríguez-Barranco, Leire Gil, Maria-Dolores Chirlaque, Eva Ardanaz, Robin Myte, Johan Hultdin, Aurora Perez-Cornago, Dagfinn Aune, Konstantinos K. Tsilidis, Demetrius Albanes, John A. Baron, Sonja I. Berndt, Stéphane Bézieau, Hermann Brenner, Peter T. Campbell, Graham Casey, Andrew T. Chan, Jenny Chang-Claude, Stephen J. Chanock, Michelle Cotterchio, Steven Gallinger, Stephen B. Gruber, Robert W. Haile, Jochen Hampe, Michael Hoffmeister, John L. Hopper, Li Hsu, Jeroen R. Huyghe, Mark A. Jenkins, Amit D. Joshi, Ellen Kampman, Susanna C. Larsson, Loic Le Marchand, Christopher I. Li, Li Li, Annika Lindblom, Noralane M. Lindor, Vicente Martín, Victor Moreno, Polly A. Newcomb, Kenneth Offit, Shuji Ogino, Patrick S. Parfrey, Paul D. P. Pharoah, Gad Rennert, Lori C. Sakoda, Clemens Schafmayer, Stephanie L. Schmit, Robert E. Schoen, Martha L. Slattery, Stephen N. Thibodeau, Cornelia M. Ulrich, Franzel J. B. van Duijnhoven, Korbinian Weigl, Stephanie J. Weinstein, Emily White, Alicja Wolk, Michael O. Woods, Anna H. Wu, Xuehong Zhang, Pietro Ferrari, Gabriele Anton, Annette Peters, Ulrike Peters, Marc J. Gunter, Karl-Heinz Wagner & Heinz Freisling. (2020) Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses. BMC Medicine 18:1.
Crossref
E. Jiménez, E. Pimentel, M.P. Cruces & A. Amaya-Chávez. (2020) Radioprotective effect of chloropyllin, protoporphyrin-IX and bilirubin compared with amifostine® in Drosophila melanogaster. Environmental Toxicology and Pharmacology 80, pages 103464.
Crossref
Nazlisadat Seyed Khoei, Gabriele Anton, Annette Peters, Heinz Freisling & Karl-Heinz Wagner. (2020) The Association between Serum Bilirubin Levels and Colorectal Cancer Risk: Results from the Prospective Cooperative Health Research in the Region of Augsburg (KORA) Study in Germany. Antioxidants 9:10, pages 908.
Crossref
Matthieu Million, Nicholas Armstrong, Saber Khelaifia, Elodie Guilhot, Magali Richez, Jean-Christophe Lagier, Gregory Dubourg, Eric Chabriere & Didier Raoult. (2020) The Antioxidants Glutathione, Ascorbic Acid and Uric Acid Maintain Butyrate Production by Human Gut Clostridia in The Presence of Oxygen In Vitro. Scientific Reports 10:1.
Crossref
Michael W. Butler, Ellen M. Armour, Jennifer A. Minnick, Marissa L. Rossi, Sydney F. Schock, Scott E. Berger & Justin K. Hines. (2020) Effects of stress-induced increases of corticosterone on circulating triglyceride levels, biliverdin concentration, and heme oxygenase expression. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 240, pages 110608.
Crossref
Evan Noel Pennell, Karl-Heinz Wagner, Sapha Mosawy & Andrew Cameron Bulmer. (2019) Acute bilirubin ditaurate exposure attenuates ex vivo platelet reactive oxygen species production, granule exocytosis and activation. Redox Biology 26, pages 101250.
Crossref
Jon Y. Takemoto, Cheng‐Wei T. Chang, Dong Chen & Garrett Hinton. (2019) Heme‐Derived Bilins. Israel Journal of Chemistry 59:5, pages 378-386.
Crossref
Ryan G. Shiels, Josif Vidimce, Andrew G. Pearson, Ben Matthews, Karl-Heinz Wagner, Andrew R. Battle, Harry Sakellaris & Andrew C. Bulmer. (2019) Unprecedented Microbial Conversion of Biliverdin into Bilirubin-10-sulfonate. Scientific Reports 9:1.
Crossref
Jessica L. Baylor & Michael W. Butler. (2019) Immune challenge-induced oxidative damage may be mitigated by biliverdin. Journal of Experimental Biology.
Crossref
Andrew C. Bulmer, Bhavisha Bakrania, Eugene F. Du Toit, Ai-Ching Boon, Paul J. Clark, Lawrie W. Powell, Karl-Heinz Wagner & John P. Headrick. (2018) Bilirubin acts as a multipotent guardian of cardiovascular integrity: more than just a radical idea. American Journal of Physiology-Heart and Circulatory Physiology 315:3, pages H429-H447.
Crossref
Melissa P. Homsher, Michael T. Astor, Justin K. Hines & Michael W. Butler. (2018) Immune challenges decrease biliverdin concentration in the spleen of northern Bobwhite quail, Colinus virginianus. Journal of Comparative Physiology B 188:3, pages 505-515.
Crossref
Sonia Blanco-Ameijeiras, Claudia Cosio & Christel S. Hassler. (2017) Long-Term Acclimation to Iron Limitation Reveals New Insights in Metabolism Regulation of Synechococcus sp. PCC7002. Frontiers in Marine Science 4.
Crossref
Michael W. Butler, Samantha C. Bociulis, Aaron R. Little, Jennifer A. Minnick, Nathan J. Ritter, Michael E. Rockman, Marissa L. Rossi & Justin K. Hines. (2017) Quantifying biliverdin in liver and spleen samples from multiple avian species. The Auk 134:1, pages 11-21.
Crossref
Ester Gonzalez-Sanchez, Maria J. Perez, Nikolaj S. Nytofte, Oscar Briz, Maria J. Monte, Elisa Lozano, Maria A. Serrano & Jose J.G. Marin. (2016) Protective role of biliverdin against bile acid-induced oxidative stress in liver cells. Free Radical Biology and Medicine 97, pages 466-477.
Crossref
Michael W. Butler & Haleigh S. Waite. (2016) Eggshell biliverdin concentration does not sufficiently predict eggshell coloration. Journal of Avian Biology 47:4, pages 491-499.
Crossref
Christine Mölzer, Marlies Wallner, Carina Kern, Anela Tosevska, Ursula Schwarz, Rene Zadnikar, Daniel Doberer, Rodrig Marculescu & Karl-Heinz Wagner. (2016) Features of an altered AMPK metabolic pathway in Gilbert’s Syndrome, and its role in metabolic health. Scientific Reports 6:1.
Crossref
Bhavisha Bakrania, Eugene F. Du Toit, Karl-Heinz Wagner, John P. Headrick & Andrew C. Bulmer. (2016) Pre- or post-ischemic bilirubin ditaurate treatment reduces oxidative tissue damage and improves cardiac function. International Journal of Cardiology 202, pages 27-33.
Crossref
Michael W. Butler & Russell A. Ligon. (2015) Interactions between Biliverdin, Oxidative Damage, and Spleen Morphology after Simulated Aggressive Encounters in Veiled Chameleons. PLOS ONE 10:9, pages e0138007.
Crossref
Karl-Heinz Wagner, Marlies Wallner, Christine Mölzer, Silvia Gazzin, Andrew Cameron Bulmer, Claudio Tiribelli & Libor Vitek. (2015) Looking to the horizon: the role of bilirubin in the development and prevention of age-related chronic diseases. Clinical Science 129:1, pages 1-25.
Crossref
Andrea W.U. Busch & Beronda L. Montgomery. (2015) Interdependence of tetrapyrrole metabolism, the generation of oxidative stress and the mitigative oxidative stress response. Redox Biology 4, pages 260-271.
Crossref
Kavita Bisht, Barbara Wegiel, Jens Tampe, Oliver Neubauer, Karl-Heinz Wagner, Leo E. Otterbein & Andrew C. Bulmer. (2014) Biliverdin modulates the expression of C5aR in response to endotoxin in part via mTOR signaling. Biochemical and Biophysical Research Communications 449:1, pages 94-99.
Crossref
Barbara WegielZsuzsanna NemethMatheus Correa-CostaAndrew C. BulmerLeo E. Otterbein. (2014) Heme Oxygenase-1: A Metabolic Nike. Antioxidants & Redox Signaling 20:11, pages 1709-1722.
Crossref
J Zheng, D A Nagda, S A Lajud, S Kumar, A Mouchli, O Bezpalko, B W O'MalleyJrJr & D Li. (2014) Biliverdin’s regulation of reactive oxygen species signalling leads to potent inhibition of proliferative and angiogenic pathways in head and neck cancer. British Journal of Cancer 110:8, pages 2116-2122.
Crossref
Christine Mölzer, Hedwig Huber, Andrea Steyrer, Gesa V. Ziesel, Marlies Wallner, Iryna Goncharova, Sergey Orlov, Marie Urbanová, Charles E. Ahlfors, Libor Vítek, Andrew C. Bulmer & Karl-Heinz Wagner. (2013) Interaction between TNFone and tetrapyrroles may account for their anti-genotoxic effects — a novel mechanism for DNA-protection. Journal of Porphyrins and Phthalocyanines 17:12, pages 1157-1166.
Crossref
Christine Mölzer, Hedwig Huber, Andrea Steyrer, Gesa V. Ziesel, Marlies Wallner, Hung T. Hong, Joanne T. Blanchfield, Andrew C. Bulmer & Karl-Heinz Wagner. (2013) Bilirubin and Related Tetrapyrroles Inhibit Food-Borne Mutagenesis: A Mechanism for Antigenotoxic Action against a Model Epoxide. Journal of Natural Products 76:10, pages 1958-1965.
Crossref
Christine Mölzer, Barbara Pfleger, Elisabeth Putz, Antonia Roßmann, Ursula Schwarz, Marlies Wallner, Andrew C. Bulmer & Karl-Heinz Wagner. (2013) In vitro DNA-damaging effects of intestinal and related tetrapyrroles in human cancer cells. Experimental Cell Research 319:4, pages 536-545.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.